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https://www.readbyqxmd.com/read/29444508/negative-aging-stereotypes-disrupt-both-the-selection-and-execution-of-strategies-in-older-adults
#1
Patrick Lemaire, Fleur Brun, Isabelle Régner
BACKGROUND: Age-based cognitive deficits are exacerbated by stereotype threat effects (i.e., the threat of being judged as cognitively incapable due to aging). We tested whether age-based stereotype threat effects can occur via impair- ing older adults' ability to select the best strategy and/or to execute strategies efficiently. METHODS: Older adults (age range: 64.3-89.5 years) were randomly assigned to a stereotype threat or control condition before taking an episodic memory task...
February 14, 2018: Gerontology
https://www.readbyqxmd.com/read/29442152/pediatric-contrast-enhanced-ultrasound-in-the-united-states-a-survey-by-the-contrast-enhanced-ultrasound-task-force-of-the-society-for-pediatric-radiology
#2
Susan J Back, Carolina Maya, Kassa Darge, Patricia T Acharya, Carol E Barnewolt, Jamie L Coleman, Jonathan R Dillman, Lynn Ansley Fordham, Misun Hwang, Annie Lim, M Beth McCarville, Marthe M Munden, Harriet J Paltiel, Frank M Volberg
BACKGROUND: The United States Food and Drug Administration (FDA) recently approved an ultrasound (US) contrast agent for intravenous and intravesical administration in children. OBJECTIVE: Survey the usage, interest in and barriers for contrast-enhanced US among pediatric radiologists. MATERIALS AND METHODS: The Contrast-Enhanced Ultrasound Task Force of the Society for Pediatric Radiology (SPR) surveyed the membership of the SPR in January 2017 regarding their current use and opinions about contrast-enhanced US in pediatrics...
February 13, 2018: Pediatric Radiology
https://www.readbyqxmd.com/read/29441812/associations-between-functional-biological-age-and-cognition-among-older-adults-in-rural-bangladesh-comparisons-with-chronological-age
#3
Ola Sternäng, Katie Palmer, Zarina N Kabir, Mohammed I Hasan, Åke Wahlin
OBJECTIVES: We constructed a functional biological age (fBioAge) indicator by using four functional variables: grip strength, forced expiratory lung volume, visual acuity, and hearing. Our aim was to compare how chronological age (ChronAge) and fBioAge are related to cognitive abilities in older adults. METHOD: We used data from the Poverty and Health in Aging project, Bangladesh. Participants ( N = 400) were 60+ years of age and diagnosed as nondemented. Examined cognitive abilities were four episodic memory measures (including recall and recognition), two verbal fluency indicators, two semantic knowledge, and two processing speed tasks...
February 1, 2018: Journal of Aging and Health
https://www.readbyqxmd.com/read/29441712/effectiveness-of-maintenance-therapy-of-lithium-vs-other-mood-stabilizers-in-monotherapy-and-in-combinations-a-systematic-review-of-evidence-from-observational-studies
#4
REVIEW
Lars Vedel Kessing, Michael Bauer, Willem A Nolen, Emanuel Severus, Guy M Goodwin, John Geddes
OBJECTIVES: For the first time to present a systematic review of observational studies on the efficiency of lithium monotherapy in comparison with other maintenance mood stabilizers in monotherapy and in combination. METHODS: As part of the International Society for Bipolar Disorders (ISBD) Task Force on Lithium Treatment, we undertook a systematic literature search of non-randomized controlled observational studies on (i) lithium monotherapy vs treatment with another maintenance mood stabilizer in monotherapy and (ii) lithium in combination with other mood stabilizers vs monotherapy...
February 14, 2018: Bipolar Disorders
https://www.readbyqxmd.com/read/29438911/biomechanical-assessment-of-dynamic-balance-specificity-of-different-balance-tests
#5
Steffen Ringhof, Thorsten Stein
Dynamic balance is vitally important for most sports and activities of daily living, so the assessment of dynamic stability has become an important issue. In consequence, a large number of balance tests have been developed. However, it is not yet known whether these tests (i) measure the same construct and (ii) can differentiate between athletes with different balance expertise. We therefore studied three common dynamic balance tests: one-leg jump landings, Posturomed perturbations and simulated forward falls...
February 10, 2018: Human Movement Science
https://www.readbyqxmd.com/read/29438568/haemodynamic-assessment-and-support-in-sepsis-and-septic-shock-in-resource-limited-settings
#6
David Misango, Rajyabardhan Pattnaik, Tim Baker, Martin W Dünser, Arjen M Dondorp, Marcus J Schultz
Background: Recommendations for haemodynamic assessment and support in sepsis and septic shock in resource-limited settings are largely lacking. Methods: A task force of six international experts in critical care medicine, all of them members of the Global Intensive Care Working Group of the European Society of Intensive Care Medicine and with extensive bedside experience in resource-limited intensive care units, reviewed the literature and provided recommendations regarding haemodynamic assessment and support, keeping aspects of efficacy and effectiveness, availability and feasibility and affordability and safety in mind...
February 9, 2018: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29436477/combat-related-foot-injuries-impact-on-gait-and-functional-outcome
#7
Loes G M de Kruijff, M Prins, A van der Krans, R Hoencamp, P van der Wurff
INTRODUCTION: Prior to deployment of the Netherlands Army Task Force Urozgan in Afghanistan, the Dutch Military and civilian healthcare systems had limited experience in treating blast injuries and their long-term consequences. This meant that guidelines for treatment and rehabilitation were lacking. The aim of this cohort study was to quantify kinematic and kinetic abnormalities in service members with foot injuries in relation to functional outcome using gait analysis. METHOD: In nine service members with combat-related talus, calcaneus and/or navicular bone (TCN) fractures and nine controls, gait parameters were measured using Gait Real-Time Analysis Interactive Lab system...
February 7, 2018: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/29435918/plp1-gene-variation-modulates-leftward-and-rightward-functional-hemispheric-asymmetries
#8
Sebastian Ocklenburg, Wanda M Gerding, Maximilian Raane, Larissa Arning, Erhan Genç, Jörg T Epplen, Onur Güntürkün, Christian Beste
Molecular neurobiological factors determining corpus callosum physiology and anatomy have been suggested to be one of the major factors determining functional hemispheric asymmetries. Recently, it was shown that allelic variations in two myelin-related genes, the proteolipid protein 1 gene PLP1 and the contactin 1 gene CNTN1, are associated with differences in interhemispheric integration. Here, we investigated whether three single nucleotide polymorphisms that were associated with interhemispheric integration via the corpus callosum in a previous study also are relevant for functional hemispheric asymmetries...
February 13, 2018: Molecular Neurobiology
https://www.readbyqxmd.com/read/29435786/standards-of-evidence-for-conducting-and-reporting-economic-evaluations-in-prevention-science
#9
D Max Crowley, Kenneth A Dodge, W Steven Barnett, Phaedra Corso, Sarah Duffy, Phillip Graham, Mark Greenberg, Ron Haskins, Laura Hill, Damon E Jones, Lynn A Karoly, Margaret R Kuklinski, Robert Plotnick
Over a decade ago, the Society for Prevention Research endorsed the first standards of evidence for research in preventive interventions. The growing recognition of the need to use limited resources to make sound investments in prevention led the Board of Directors to charge a new task force to set standards for research in analysis of the economic impact of preventive interventions. This article reports the findings of this group's deliberations, proposes standards for economic analyses, and identifies opportunities for future prevention science...
February 12, 2018: Prevention Science: the Official Journal of the Society for Prevention Research
https://www.readbyqxmd.com/read/29434523/allergic-sensitization-to-common-pets-cats-dogs-according-to-different-possible-modalities-of-exposure-an-italian-multicenter-study
#10
G Liccardi, L Calzetta, G Baldi, A Berra, L Billeri, M Caminati, P Capano, E Carpentieri, A Ciccarelli, M A Crivellaro, M Cutajar, M D'Amato, I Folletti, F Gani, D Gargano, D Giannattasio, M Giovannini, C Lombardi, M Lo Schiavo, F Madonna, M Maniscalco, A Meriggi, C Micucci, M Milanese, C Montera, G Paolocci, R Parente, A Pedicini, R Pio, F Puggioni, M Russo, A Salzillo, P Scavalli, N Scichilone, B Sposato, A Stanziola, G Steinhilber, A Vatrella, P Rogliani, G Passalacqua
Background: The query "are there animals at home?" is usually administered for collecting information on anamnesis. This modality to consider exposure to pet allergens constitutes a potential bias in epidemiological studies and in clinical practice. The aim of our study was to evaluate/quantify different modalities of exposure to cat/dog in inducing allergic sensitization. Methods: Thirty Italian Allergy units participated in this study. Each centre was required to collect the data of at least 20 consecutive outpatients sensitized to cat/dog allergens...
2018: Clinical and Molecular Allergy: CMA
https://www.readbyqxmd.com/read/29433963/pertuzumab-and-trastuzumab-with-or-without-metronomic-chemotherapy-for-older-patients-with-her2-positive-metastatic-breast-cancer-eortc-75111-10114-an-open-label-randomised-phase-2-trial-from-the-elderly-task-force-breast-cancer-group
#11
Hans Wildiers, Konstantinos Tryfonidis, Lissandra Dal Lago, Peter Vuylsteke, Giuseppe Curigliano, Simon Waters, Barbara Brouwers, Sevilay Altintas, Nathan Touati, Fatima Cardoso, Etienne Brain
BACKGROUND: Despite the high incidence of metastatic breast cancer and its related mortality in the elderly population, our knowledge about optimal treatment for older patients with cancer is far from adequate. We aimed to evaluate the efficacy of dual anti-HER2 treatment with or without metronomic chemotherapy in older patients with HER2-positive metastatic breast cancer. METHODS: We did a multicentre, open-label, randomised, phase 2 trial in 30 centres from eight countries in Europe, in patients with histologically proven, HER2-positive metastatic breast cancer, without previous chemotherapy for metastatic disease, who were 70 years or older, or 60 years or older with confirmed functional restrictions defined by protocol, and had a life expectancy of more than 12 weeks and a performance status according to WHO scale of 0-3...
February 9, 2018: Lancet Oncology
https://www.readbyqxmd.com/read/29433466/problem-drinking-among-flemish-students-beverage-type-early-drinking-onset-and-negative-personal-social-consequences
#12
Sara De Bruyn, Edwin Wouters, Koen Ponnet, Joris Van Damme, Lea Maes, Guido Van Hal
BACKGROUND: Although alcohol is socially accepted in most Western societies, studies are clear about its associated negative consequences, especially among university and college students. Studies on the relationship between alcohol-related consequences and both beverage type and drinking onset, however, are scarce, especially in a European context. The aim of this research was, therefore, twofold: (1) What is the relationship between beverage type and the negative consequences experienced by students? and (2) Are these consequences determined by early drinking onset? We will examine these questions within the context of a wide range of alcohol-related consequences...
February 12, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29432903/use-of-the-limbs-and-things-hysterectomy-model-to-describe-the-process-for-establishing-validity
#13
Christopher C DeStephano, Anita H Chen, Michael Heckman, Nicolette T Chimato, Paulami Guha, Mariana Espinal, Tri A Dinh
OBJECTIVE: Demonstrate the process for establishing or refuting validity for the Limbs and Things hysterectomy model. DESIGN: Prospective study using Kane's framework for establishing validity (Canadian Task Force Classification: II-2). SETTING: Laparoscopic hysterectomy (TLH) assessments completed in the operating room (OR) and simulation at three academic medical centers. PARTICIPANTS: OB/GYN residents (n=26 post-graduate year 3-4), a gynecologic oncology fellow (post-graduate year 5), and a gynecology oncology attending...
February 9, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29432902/anterior-focal-adenomyosis-and-bladder-deep-infiltrative-is-there-a-link
#14
Louis Marcellin, Pietro Santulli, Sara Bortolato, Cécile Morin, Anne Elodie Millisher, Bruno Borghese, Charles Chapron
STUDY OBJECTIVE: To evaluate the association between bladder deep infiltrating endometriosis (DIE) and anterior focal adenomyosis of the outer myometrium (aFAOM) diagnosed by preoperative magnetic resonance imaging (MRI). DESIGN: An observational, cross-sectional study using prospectively collected data (Canadian Task Force classification II-2). SETTING: Single university tertiary referral center. PATIENTS: All non-pregnant women less than 42-years-old who had undergone complete surgical exeresis of endometriotic lesions...
February 9, 2018: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29432374/development-of-an-outpatient-guideline-for-optimal-anticoagulation-bridging-in-patients-with-durable-mechanical-circulatory-support
#15
Amy A Levesque, Jessica M Rimsans, Katelyn W Sylvester, Erin N Lyons, Katie A Frankel, Lara L Coakley, Maryclare Hickey, Krystin A Montoya, Mandeep R Mehra, Michael M Givertz, Garrick C Stewart, Jean M Connors
Patients with durable mechanical circulatory support are at increased risk of thromboembolic and bleeding complications. Current guidelines recommend that these patients receive chronic anticoagulation with warfarin to maintain a target international normalized ratio (INR) as specified by device manufacturers. Limited data exist regarding management of subtherapeutic INRs in this setting. To standardize clinical practice at our institution, we assembled a multidisciplinary task force including members from various specialties to develop a guideline for managing subtherapeutic INRs that incorporates published data and expert opinion...
March 2018: Critical Pathways in Cardiology
https://www.readbyqxmd.com/read/29432323/changes-in-motor-coordination-induced-by-local-fatigue-during-a-sprint-cycling-task
#16
Niels-Peter Brøchner Nielsen, François Hug, Arnaud Guével, Floren Colloud, Julien Lardy, Sylvain Dorel
PURPOSE: This study investigated how muscle coordination is adjusted in response to a decrease in the force-generating capacity of one muscle group during a sprint cycling task. METHODS: Fifteen participants were tested during a sprint before and after a fatigue electromyostimulation protocol was conducted on the quadriceps of one leg. Motor coordination was assessed by measuring myoelectrical activity, pedal force and joint power. RESULTS: The decrease in force-generating capacity of the quadriceps (-28...
February 9, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29431571/cross-cultural-adaptation-of-the-physician-orders-for-life-sustaining-treatment-form-to-brazil
#17
Vania F S Mayoral, Fernanda B Fukushima, Aniela M Rodrigues, Raissa P Carvalho, Larissa P Carvalho, Leandro A F V Pinheiro, Bertha F Polegato, Marcos F Minicucci, Rick Bassett, Alvin H Moss, Karl E Steinberg, Edison I O Vidal
BACKGROUND: The Physician Orders for Life-Sustaining Treatment (POLST) paradigm is considered one of the most important strategies to respect patients' values at the end of life in the United States. The cross-cultural adaptation of POLST entailed several methodological considerations, which may be informative for international researchers who may also consider bringing POLST to their countries as a means to promote care at the end of life that is consistent with patients' preferences...
February 12, 2018: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/29431364/chronic-kidney-disease-detection-and-evaluation
#18
David Y Gaitonde, David L Cook, Ian M Rivera
Chronic kidney disease affects 47 million people in the United States and is associated with significant health care costs, morbidity, and mortality. Because this disease can silently progress to advanced stages, early detection is critical for initiating timely interventions. Multiple guidelines recommend at least annual screening with serum creatinine, urine albumin/creatinine ratio, and urinalysis for patients with risk factors, particularly diabetes mellitus, hypertension, and a history of cardiovascular disease...
December 15, 2017: American Family Physician
https://www.readbyqxmd.com/read/29426799/the-quick-sequential-organ-failure-assessment-qsofa-identifies-septic-patients-in-the-out-of-hospital-setting
#19
Paul Barbara, Christopher Graziano, William Caputo, Ilya Litvak, Dominick Battinelli, Barry Hahn
BACKGROUND: Recently a multispecialty, multinational task force convened to redefine the criteria for organ dysfunction, sepsis, severe sepsis, and septic shock. The study recommended the quick sequential organ failure assessment (qSOFA) score to identify sepsis patients. The qSOFA is felt to be the initial screen to prompt a more in-depth sepsis workup. This may be particularly true in resource-limited environments such as the prehospital arena. OBJECTIVES: The goal of this study was to identify whether emergency medical services (EMS) patients who met all three qSOFA criteria correlated with an emergency department (ED) identification of sepsis...
January 31, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29426038/effect-of-short-term-training-on-fine-motor-control-in-trigeminally-innervated-versus-spinally-innervated-muscles
#20
Hong Zhang, Abhishek Kumar, Xiaoping Luo, Krister Svensson, Mats Trulsson, Peter Svensson
We hypothesized that the trigeminally innervated jaw muscles and spinally innervated hand muscles would differ in the force control and muscle activity when similar fine motor training tasks are performed. Sixteen healthy volunteers performed six series (with ten trials each) of an oral fine motor task (OFMT) and a hand fine motor task (HFMT), in random order. The task was to hold-and-break a test material (5 cm spaghetti pasta) placed on the force transducer between either their anterior teeth (OFMT) or the thumb and the index finger (HFMT)...
February 6, 2018: Human Movement Science
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