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Biodegradable polymer stent

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https://www.readbyqxmd.com/read/28109057/comparison-of-two-biodegradable-polymer-based-sirolimus-eluting-stents-with-varying-elution-and-absorption-kinetics-in-patients-with-acute-myocardial-infarction-a-subgroup-analysis-of-the-panda-iii-trial
#1
Changdong Guan, Bo Xu, Shubin Qiao, Lei Qin, Yi Li, Zhanquan Li, Yong Guo, Zhongwei Sun, Lei Song, Runlin Gao
BACKGROUND: Implantation of early-generation metallic drug-eluting stents (DES) in patients with acute myocardial infarction (AMI) is associated with poor vessel wall healing. Use of biodegradable polymer (BP) DES might improve safety outcomes; however, the impact of varying drug elution and polymer absorption kinetics of BP-DES on clinical outcomes in the AMI population is unknown. METHODS: This subgroup analysis of the randomized PANDA III trial included 732 patients (366 in each group) presenting with recent (<1 month) AMI...
January 21, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28105994/angiographic-outcomes-of-orsiro-biodegradable-polymer-sirolimus-eluting-stents-and-resolute-integrity-durable-polymer-zotarolimus-eluting-stents-results-of-the-orient-trial
#2
Si-Hyuck Kang, Woo-Young Chung, Joo Myung Lee, Jin-Joo Park, Chang-Hwan Yoon, Jung-Won Suh, Young-Seok Cho, Joon-Hyung Doh, Jin Man Cho, Jang-Whan Bae, Tae-Jin Youn, In-Ho Chae
AIMS: We performed a randomised controlled open-label non-inferiority trial to compare angiographic outcomes between the ultra-thin strut, biodegradable hybrid polymer Orsiro sirolimus-eluting stent (O-SES) and the durable biocompatible polymer Resolute Integrity zotarolimus-eluting stent (R-ZES). METHODS AND RESULTS: A total of 372 patients planned to undergo percutaneous coronary revascularisation were randomly assigned 2:1 to treatment with O-SES or R-ZES (250 and 122 patients, respectively)...
January 20, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28104206/randomized-multicenter-trial-investigating%C3%A2-angiographic-outcomes-of%C3%A2-hybrid-sirolimus-eluting-stents-with%C3%A2-biodegradable-polymer-compared-with%C3%A2-everolimus-eluting-stents-with-durable%C3%A2-polymer-in-chronic-total-occlusions-the-prison-iv-trial
#3
Koen Teeuwen, René J van der Schaaf, Tom Adriaenssens, Jacques J Koolen, Pieter C Smits, José P S Henriques, Paul H M J Vermeersch, R Melvyn Tjon Joe Gin, Bastiaan E Schölzel, Johannes C Kelder, Jan G P Tijssen, Pierfrancesco Agostoni, Maarten J Suttorp
OBJECTIVES: The aim of this study was to investigate the efficacy and safety of the hybrid ultrathin-strut sirolimus-eluting stent (SES) with biodegradable polymer compared with the thin-strut everolimus-eluting stent (EES) with durable polymer in successfully recanalized chronic total occlusions (CTOs). BACKGROUND: The introduction of drug-eluting stents revolutionized the treatment of CTOs. However, limited data are available on new-generation drug-eluting stents with biodegradable polymer in CTOs...
January 23, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28096181/long-term-8-10%C3%A2-years-outcomes-after-biodegradable-polymer-coated-biolimus-eluting-stent-implantation
#4
Masanobu Ohya, Shunsuke Kubo, Akimune Kuwayama, Katsuya Miura, Takenobu Shimada, Hidewo Amano, Yusuke Hyodo, Suguru Otsuru, Seiji Habara, Takeshi Tada, Hiroyuki Tanaka, Yasushi Fuku, Harumi Katoh, Tsuyoshi Goto, Kazushige Kadota
OBJECTIVE: Efficacy and safety data on biodegradable polymer-coated biolimus-eluting stent (BP-BES) are currently limited to 5 years. We evaluated longer term (8-10 years) clinical and angiographic outcomes after BP-BES implantation. METHODS: Between 2005 and 2008, 243 patients (301 lesions) underwent BP-BES implantation. The primary clinical outcome measure was defined as any target lesion revascularisation (TLR). Absolute serial angiographic studies without any concomitant TLR within 2 years after the procedure were performed in 55 patients (65 lesions) at postprocedure, mid-term (within 1 year), late term (between 1 and 2 years) and very late term (beyond 2 years)...
January 17, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28068065/sustained-nitric-oxide-release-from-a-tertiary-s-nitrosothiol-based-polyphosphazene-coating
#5
Alec Lutzke, Jesus B Tapia, Megan J Neufeld, Melissa M Reynolds
Nitric oxide (NO) occurs naturally in mammalian biochemistry as a critical signaling molecule and exhibits antithrombotic, antibacterial, and wound-healing properties. NO-forming biodegradable polymers have been utilized in the development of antithrombotic or antibacterial materials for biointerfacial applications, including tissue engineering and the fabrication of erodible coatings for medical devices such as stents. Use of such NO-forming polymers has frequently been constrained by short-term release or limited NO storage capacity and has led to the pursuit of new materials with improved NO release function...
January 9, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28017123/current-state-of-bioabsorbable-polymer-coated-drug-eluting-stents
#6
Akinapelli Absdhilash, Jack P Chen, Kristine Roy, Joseph Donnelly, Keith Dawkins, Barbara Huibregtse, Dongming Hou
Drug-eluting stents (DES) have been shown to significantly reduce clinical and angiographic restenosis compared to bare metal stents (BMS). The polymer coatings on DES elute antiproliferative drugs to inhibit intimal proliferation and prevent restenosis after stent implantation. Permanent polymers which do not degrade in vivo may increase the likelihood of stent-related delayed arterial healing or polymer hypersensitivity. In turn, these limitations may contribute to an increased risk of late clinical events...
December 22, 2016: Current Cardiology Reviews
https://www.readbyqxmd.com/read/27976797/comparable-vascular-response-of-a-new-generation-sirolimus-eluting-stents-when-compared-to-fluoropolymer-everolimus-eluting-stents-in-the-porcine-coronary-restenosis-model
#7
Piotr P Buszman, Magdalena J Michalak, Maciej Pruski, Carlos Fernandez, Michał Jelonek, Adam Janas, Claudine Savard, Beata Gwiazdowska-Nowotka, Aleksander Żurakowski, Wojciech Wojakowski, Paweł E Buszman, Krzysztof Milewski
BACKGROUND: Novel sirolimus eluting stents (SES) have shown non-inferior clinical outcomes when compared to everolimus eluting stents (EES), however only limited preclinical data have been published. Therefore, we evaluate vascular response of a new generation biodegradable polymer SES (BP-SES: Alex Plus, Balton) and fluoropolymer EES (EES: Xience Pro, Abbott) in the porcine coronary restenosis model. METHODS: A total of 40 stents were implanted with 120% overstretch in coronaries of 17 domestic swine: 16 BP-SES, 16 EES and 8 bare metal controls (BMS)...
2016: Cardiology Journal
https://www.readbyqxmd.com/read/27970269/tct-106-outcomes-after-revascularization-with-sirolimus-eluting-and-birolimus-eluting-stents-with-biodegradable-polymer-in-patients-with-acute-coronary-syndromes-from-the-sort-out-vii-trial
#8
Christian Oliver Fallesen, Evald Christiansen, Hans Erik Bøtker, Bent Raungaard, Michael Maeng, Anders Junker, Lars Jakobsen, Svend Eggert Jensen, Johnny Kahlert, Lisette Okkels Jensen
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27970227/tct-836-endothelial-cell-coverage-and-inflammation-comparing-cobra-polyzene-f-pzf-coated-stent-to-durable-fluoropolymer-and-biodegradable-polymer-drug-eluting-stents-in-a-rabbit-model
#9
Kazuyuki Yahagi, Frank Kolodgie, Daivid Cheng, Eduardo Acampado, Hiroyoshi Mori, Khaja Chinnakondepali, Maria Romero, Aloke Finn, Renu Virmani
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27970224/tct-835-endothelial-function-assessed-by-expression-of-adherens-junctions-and-inflammation-between-durable-and-biodegradable-polymer-drug-eluting-stents-in-the-rabbit-iliofemoral-model
#10
Kazuyuki Yahagi, Frank Kolodgie, Daivid Cheng, Eduardo Acampado, Liang Guo, Hiroyoshi Mori, Khaja Chinnakondepali, Maria Romero, Laura Perkins, Aloke Finn, Renu Virmani
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27970070/tct-69-a-randomized-comparison-of-the-second-generation-biodegradable-polymer-sirolimus-eluting-stent-excel-ii-and-the-first-generation-excel-i-stent-in-patients-with-de-novo-coronary-lesions-clinical-and-angiographic-outcomes-of-the-credit-ii-trial
#11
Yaling Han, Yuejin Yang, Bo Xu, Yong Sun, Zuyi Yuan, Haichang Wang, Jinghua Liu, Huiliang Liu, Genshan Ma, Geng Wang, Quanmin Jing, Xiaozeng Wang
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27970069/tct-70-final-5-year-results-from-the-compare-ii-trial-comparison-between-the-durable-polymer-coated-everolimus-eluting-xience-promus-stent-and-the-biodegradable-polymer-coated-biolimus-eluting-nobori-stent-in-all-comer-population
#12
Pieter Smits, Sjoerd H Hofma, Mario Togni, Peter den Heijer, Antonio Serra, Ton Slagboom, Ramiro Trillo, Mariano Valdes, Jose Vazquez, Vassilis Voudris
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969930/tct-561-long-term-vascular-response-to-permanent-polymer-everolimus-eluting-stent-vs-biodegradable-polymer-biolimus-eluting-stent-five-year-follow-up-optical-coherence-tomography-study
#13
Shoichi Kuramitsu, Shinjo Sonoda, Hiroyuki Jinnouchi, Yoshitaka Muraoka, Takenori Domei, Shinichi Shirai, Kenji Ando
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969853/tct-495-a-prospective-9-month-comparison-of-the-coronary-vasomotor-response-associated-with-a-biodegradable-polymer-sirolimus-eluting-stent-and-a-bare-metal-stent
#14
Rodrigo Souza, Adriano Barbosa, Marco Tulio Souza, Marcelo Parente, Bárbara Freitas Fiorin, Jose Marconi Almeida Sousa, Claudia Alves, Adriano Caixeta, Antonio Carlos Carvalho
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969852/tct-494-very-long-term-8-year-angiographic-and-clinical-outcomes-after-biodegradable-polymer-based-biolimus-eluting-stent-implantation
#15
Masanobu Ohya, Akimune Kuwayama, Katsuya Miura, Takenobu Shimada, Hidewo Amano, Shunsuke Kubo, Yusuke Hyodo, Suguru Otsuru, Seiji Habara, Takeshi Tada, Hiroyuki Tanaka, Yasushi Fuku, Tsuyoshi Goto, Kazushige Kadota
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969841/tct-485-a-study-of-safety-and-efficacy-of-biodegradable-polymer-coated-everolimus-eluting-coronary-stent-system-everoflex-at-intermediate-follow-up-in-real-world-scenario
#16
Rajasekhar Durgaprasad, Velam Vanajakshamma, A Vamsidhar, Latheef Kasala, Sreedhar Naik Kanavat, Pathakota Sudhakar Reddy
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969833/tct-476-a-randomized-comparison-of-novel-biodegradable-polymer-and-durable-polymer-coated-cobalt-chromium-sirolimus-eluting-stents-three-year-outcomes-of-the-i-love-it-2-trial
#17
Bo Xu, Changdong Guan, Quanmin Jing, Kai Xu, Yuejin Yang, Yaling Han
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969832/tct-473-a-randomized-comparison-of-biodegradable-polymer-and-permanent-polymer-coated-platinum-chromium-everolimus-eluting-coronary-stents-in-china-evolve-china-study
#18
Yaling Han, Yuejin Yang, Guosheng Fu, X I Su, Tiemin Jiang, Wenyue Pang, Jiyan Chen, Zuyi Yuan, Haichang Wang, Huiliang Liu, Mingdong Zhang, Rider Brito Filho
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969825/tct-468-acute-thrombogenicity-and-inflammation-in-response-to-a-durable%C3%A2-fluoropolymer-everolimus-eluting-stent-relative-to-a%C3%A2-contemporary-sirolimus-eluting-stent-with-an-abluminal-biodegradable-polymer-coating
#19
Sho Torii, Frank Kolodgie, Daivid Cheng, Eduardo Acampado, Kazuyuki Yahagi, Hiroyoshi Mori, Maria Romero, Laura Perkins, Syed Hossainy, Stephen Pacetti, Aloke Finn, Renu Virmani
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27969820/tct-462-efficacy-and-safety-of-biodegradable-polymer-everolimus-eluting-stents-versus-durable-polymer-biolimus-eluting-stents-a-direct-comparison-meta-analysis-of-8-476-patients-from-randomized-trials
#20
Chirag Bavishi, Saurav Chatterjee, Janine Pöss, Pedro Moreno
No abstract text is available yet for this article.
November 1, 2016: Journal of the American College of Cardiology
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