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Maíra Duarte Cardoso, Leila Soledade Lemos, Emily Moraes Roges, Jailson Fulgencio de Moura, Davi Castro Tavares, Carlos Alexandre R Matias, Dália Dos Prazeres Rodrigues, Salvatore Siciliano
AIMS: To perform a microbiological survey regarding the presence, prevalence and characterization of Aeromonas sp. and Vibrio sp. in debilitated wrecked marine birds recovered from the center-north coast of the state of Rio de Janeiro, Brazil. METHODS AND RESULTS: Swabs obtained from 116 alive and debilitated wrecked marine birds, comprising 19 species, from the study area were evaluated by biochemical methods. Antimicrobial susceptibility tests and pathogenicity gene screening were performed for bacterial strains of public health importance...
January 21, 2018: Journal of Applied Microbiology
Yasunobu Iwai, Keisuke Noda, Mizuho Yamazaki, Ayako Kato, Masaru Mezawa, Hideki Takai, Yohei Nakayama, Yorimasa Ogata
Follicular dendritic cell-secreted protein (FDC-SP) is a secreted protein expressed in follicular dendritic cells, periodontal ligament and junctional epithelium. To elucidate the transcriptional regulation of the human FDC-SP gene by tumor necrosis factor-α (TNF-α), we conducted real-time PCR, Western blotting, transient transfection analyses with chimeric constructs of the FDC-SP gene promoter linked to a luciferase reporter gene, gel mobility shift and chromatin immunoprecipitation assays using Ca9-22 gingival epithelial cells...
January 22, 2018: Genes to Cells: Devoted to Molecular & Cellular Mechanisms
Masatoshi Ohnishi, Tomoka Urasaki, Kyohei Egusa, Chihiro Kunobu, Tomoki Harada, Reika Shinkado, Hitomi Nishi, Shoji Maehara, Chinami Kitamura, Toshiyuki Hata, Kazuyoshi Ohashi, Hirotaka Shibuya, Atsuko Inoue
To elucidate the anti-inflammatory mechanism of Curcuma sp., we investigated whether dehydrocurdione, a sesquiterpene contained in Curcuma sp., induces heme oxygenase (HO)-1, an antioxidative enzyme, in RAW 264.7 macrophages. Dehydrocurdione was extracted from the rhizome of Curcuma sp., and its purity was verified by high performance liquid chromatography. Treatment with 10-100 μM dehydrocurdione transiently and concentration-dependently increased HO-1 mRNA and protein levels. Docking simulation suggested the presence of the Michael reaction between dehydrocurdione and Kelch-like ECH-associated protein (Keap)1 keeping nuclear factor-erythroid2-related-factor (Nrf)2, a transcription factor, in the cytoplasm...
January 22, 2018: Phytotherapy Research: PTR
Fang Yang, Pan Zhang, Xianli Shi, Kangxin Li, Minwei Wang, Yeqi Fu, Xinxin Yan, Jianxiong Hang, Guoqing Li
Present study was performed to identify the species of ascarids from macaw parrot, Ara chloroptera, in China. Total 6 ascarids (3 males and 3 females) were collected in the feces of 3 macaws at Guangzhou Zoo in Guangdong Province, China. Their morphological characteristics with dimensions were observed under a light microscope, and their genetic characters were analyzed with the partial 18S rDNA, ITS rDNA and nad4 gene sequences, respectively. Results showed that all worms have no interlabia but male worms have two alate spicules, well-developed precloacal sucker and a tail with ventrolateral caudal alae and 11 pairs of papillae...
January 16, 2018: Parasitology International
Theresa Louise-Bender Pape, Bridget Smith, Judith Babcock-Parziale, Charlesnika T Evans, Amy A Herrold, Kelly Phipps Maieritsch, Walter M High
OBJECTIVE: To comprehensively estimate the diagnostic accuracy and reliability of the Department of Veterans Affairs (VA) TBI Clinical Reminder Screen (TCRS). DESIGN: Cross-sectional, prospective, observational study using the Standards for Reporting of Diagnostic Accuracy (STARD) criteria. SETTING: Three VA Polytrauma Network Sites. PARTICIPANTS: 433 Operation Iraqi Freedom, Operation Enduring Freedom (OEF/OIF) Veterans...
January 17, 2018: Archives of Physical Medicine and Rehabilitation
Marie-Theres Vielberg, Verena C Bauer, Michael Groll
The 20S proteasome is a key player in eukaryotic and archaeal protein degradation, but its progenitor in eubacteria is unknown. Recently, the ancestral β-subunit protein (Anbu) was predicted to be the evolutionary precursor of the proteasome. We crystallised Anbu from Hyphomicrobium sp. strain MC1 in four different space groups and solved the structures by SAD-phasing and Patterson search calculation techniques. Our data reveal that Anbu adopts the classical fold of Ntn-hydrolases, but its oligomeric state differs from that of barrel-shaped proteases...
January 17, 2018: Journal of Molecular Biology
S Llamas-Velasco, A García-Redondo, A Herrero-San Martín, V Puertas Martín, M González-Sánchez, D A Pérez-Martínez, A Villarejo-Galende
We present a 86-year-old woman without relevant medical history and two brothers who died by dementia, who started at 55 years with depression and personality changes with ongoing worsening (>30 years) and functional decline. Screening dementia blood test and brain magnetic resonance imaging did not show results that pointed to a secondary cause. The patient met the diagnostic criteria for possible behavioral frontotemporal dementia with a slow progression (bvFTD-SP), suggesting a benign variant. A genetic study confirmed a C9ORF72 hexanucleotide expansion, making this the sixth case mentioned in the literature...
January 22, 2018: Neurocase
Siwen Niu, Qingmei Liu, Jin-Mei Xia, Chun-Lan Xie, Zhu-Hua Luo, Zongze Shao, Guang-Ming Liu, Xian-Wen Yang
To discover anti-food allergic components from deep-sea-derived microorganisms. A systematic chemical investigation was conducted on the Atlantic hydrothermal fungus Graphostroma sp. MCCC 3A00421. Consequently, nine new (1-9) and 19 known (10‒28) polyketides were isolated. The planar structures of the new compounds were elucidated mainly by detailed analysis of their NMR and HRESIMS data, while the absolute configurations were established using the modified Mosher's method in association with ECD spectra...
January 22, 2018: Journal of Agricultural and Food Chemistry
Xiangwei Cheng, Biao Zhou, Huazhang Liu, Chao Huo, Wanjing Ding
One new indolocarbazole alkaloid, 12-N-methyl-k252c, together with eight known indolocarbazoles were isolated from the rice solid fermentation of the marine-derived Streptomyces sp. A22. Their structures were elucidated on the basis of spectroscopic methods (UV, IR, HRESITOF MS, 1D NMR and 2D NMR). All of these compounds were evaluated for bromodomain-containing protein 4 (BRD4) inhibitory activities and cytotoxic activity assay, respectively. Compounds 4 and 5 showed moderate cytotoxic activity with an IC50 value of 3...
January 22, 2018: Natural Product Research
Guoping Ye, Meiling Su, Dingyu Zhu, Linyun Zhang, Wang Lin, Li Huang, Mingxia Wu
OBJECTIVE: To observe the effects of conventional western medication and joss stick moxibustion combined with pricking and cupping for herpes zoster in acute stage, and to explore its analgesic mechanism. METHODS: Seventy patients with acute herpes zoster were randomized into an observation group (33 cases after 2 dropping) and a control group (34 cases after 1 dropping). Patients in the observation group were treated with joss stick moxibustion combined with pricking and cupping at local ashi points for 7 times, once every other day...
December 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Yu Qin, Wei Yi, Shuxiong Lin, Chunfang Yang, Zemin Zhuang
OBJECTIVE: To compare the efficacy differences between abdominal acupuncture and western medication for diarrhea irritable bowel syndrome (IBS-D). METHODS: Sixty-one patients with IBS-D were randomly assigned into an acupuncture group (30 cases after 1 dropping) and a western medication group (28 cases after 2 dropping). Acupuncture was used at Yinqiguiyuan points [Zhongwan (CV 12), Xiawan (CV 10), Qihai (CV 6), Guanyuan (CV 4)], Fusiguan points [bilateral Huaroumen (ST 24), Wailing (ST 26)], Tiaopiqi point [bilateral Daheng (SP 15)], once every other day, 3 times a week...
December 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Xuesi Hou, Qingchen Zhou, Lei Wang, Lu Cheng, Jiping Zhao
To discuss the acupuncture and moxibustion thoughts of diagnosis and treatment for secondary dysmenorrhea of adenomyosis on the basis of disease location and pathogenesis. In clinic, we take the "principle, method, prescription, acupoint and technic" as the outline, paying attention to identify disease location and establishing the method of "promoting blood to remove stasis, regulating thoroughfare vessel and conception vessel" on the basis of the pathogenesis of "stasis obstructing uterus, disharmony of thoroughfare vessel and conception vessel"...
October 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Siyuan Xin, Zhixin Yang, Jianen Guo, Hongtong Lu, Pei Wang, Jia Pang, Huan Zhang
The acupoint effect of Sanyinjiao (SP 6) and Xuanzhong (GB 39) as well as the internal relation of Sanyinjiao (SP 6)-Xuanzhong (GB 39) were analyzed in this paper to explore the relationship between opposite acupoints and acupoint effect. It was found both Sanyinjiao (SP 6) and Xuanzhong (GB 39) had acupoint effects, and the two acupoints had close relationship in acupoint effects (specificity along meridian and specificity of acupoints), acupoint-meridian relationship (anatomical locations, meridians and organs, indications)...
October 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Xiaotong Li, Huanfang Xu, Yigong Fang, Jie Shang, Huisheng Yang, Xuelin Zhou, Minglong Zhang
OBJECTIVE: To investigate the effect and safety of acupuncture with regulating menstruation to promote pregnancy for diminished ovarian reverse (DOR). METHODS: According to prospective case series, 46 patients were observed and finally 40 cases were included. The acupoints were ① Baihui (GV 20), Shenting (GV 24), Guanyuan (CV 4) and bilateral Benshen (GB 13), Huangshu (KI 16), Dahe (KI 12), Luanchao (Extra), Zusanli (ST 36), Sanyinjiao (SP 6), Taixi (KI 3), Taichong (LR 3) and ② bilateral Shenshu (BL 23) and Ciliao (BL 32)...
October 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Shunji Wang, Gaxi Ye, Yu Zhang, Shuting Guan, Xiufen Liu, Wenjing Ren
OBJECTIVE: To compare the effects of flipping moxibustion of Hui medicine combined with western medication and simple western medication for rheumatoid arthritis with cold dampness bi syndrome. METHODS: Eighty patients were randomly assigned into an observation group and a control group, 40 cases in each group. Oral methotrexate (1 time a week) and sulfasalazine (twice a day except the day for methotrexate) were used in the two groups. Patients in the observation group were treated with flipping moxibustion of Hui medicine, twice a week...
October 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Yuxia Yang, Rong Xiang, Yanyan Liu, E Chang, Yanling Huo
OBJECTIVE: To explore the methods for the therapeutic effect improvement in the treatment of post-stroke urinary retention. METHODS: Sixty-three patients of post-stroke urinary retention were randomized into an observation group (32 cases) and a control group (31 cases). The routine clinical medication of neurology and basic rehabilitation were adopted in the two groups. Additionally, in the control group, the intermittent urinary catheterization and bladder function training were applied...
October 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Xiangbin Wang, Xuerong Xie, Meijin Hou, Xiaoling Wang, Jian Chen, Jiao Yu, Xiang Li
OBJECTIVE: To observe the kinetic change that reflects joint loading in different planes during stair climbing in knee osteoarthritis (KOA) after electroacupuncture (EA) by three-dimensional motion analysis, so as to provide reference for its biomechanical mechanism treated with acupuncture. METHODS: Forty KOA patients, in accordance with the random number table, were assigned into an observation group and a control group, 20 cases in each one and finally 18 cases completed...
October 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Juan Yang, Ying Liu, Jian Huang, Jinbang Xu, Xiumi You, Qiuping Lin, Junxin Zhang, Jingjing Dun, Shan Huang
OBJECTIVE: To explore the effect difference between acupuncture combined with Chinese medicine of artificial cycle therapy on the basis of western medication and simple western medication for polycystic ovarian syndrome (PCOS) of phlegm damp type with insulin resistance, and to explore its mechanism. METHODS: Sixty patients were randomly assigned into an observation group and a control group, 30 cases in each group. Patients of the control group began to take letrozole and metformin orally on the third menstrual day...
November 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Shangqing Li, Aiai Dong, Zhijun Hu, Xinzhi Zhu
In theory of TCM, the root cause of knee osteoarthritis (xibi) is the deficiency of liver and kidney, while the symptoms are involved with multiple damages of muscles, tendons and joints. The exogenous evil of wind, coldness, dampness and heat as well as the blood stasis usually block the meridians and collaterals, which cause the knee osteoarthritis. Professor JI Laixi selects acupoints based on syndrome differentiation, and treats both root cause and symptoms. He attaches importance to the ashi points, and takes pain as acupoints...
January 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
Meiren Chen, Rong Hu, Jian Lin, Yuhui Huang, Wanping Mao, Yuanying Wen, Gaole Dai
OBJECTIVE: To observe the effects among aconite cake-separated moxibustion, moxibustion and acupuncture for knee osteoarthritis (KOA) with kidney-marrow deficiency and to explore the feasibility of cake-separated moxibustion as a home remedy solution. METHODS: Ninety patients were randomized into an aconite cake-separated moxibustion group, a moxibustion group and an acupuncture group, 30 cases in each one. The acupoints in the three groups were Neixiyan (EX-LE 4), Dubi (ST 35) in the affected side, and bilateral Xuehai (SP 10), Liangqiu (ST 34), Heding (EX-LE 2), Shenshu (BL 23) and Zusanli (ST 36)...
January 12, 2018: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
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