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https://www.readbyqxmd.com/read/28806830/-the-size-and-proportion-of-the-interphalangeal-finger-joints-an%C3%A2-anatomic-study
#1
Christoph Faymonville, Thomas Gausepohl, Lars Peter Müller, Michael Hackl
Background This study aimed to evaluate the size of the joint surfaces of the proximal and distal interphalangeal finger joints. Material and Methods 117 proximal and distal interphalangeal joints of 30 formalin-fixed hands of body donors were included in this study. The size of the articular surface was determined for each joint. Results The mean size of the proximal joint surface of the distal interphalangeal joint is 56.1 mm(2); the distal joint surface averages 30.9 mm(2) (ratio: 1.8:1). The size of the proximal articular surface of the proximal interphalangeal joint is 92...
August 2017: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://www.readbyqxmd.com/read/28806736/unravelling-the-interplay-of-sphingolipids-and-tgf-%C3%AE-signaling-in-the-human-corneal-stroma
#2
Sarah E Nicholas, Tyler G Rowsey, Shrestha Priyadarsini, Nawajes A Mandal, Dimitrios Karamichos
PURPOSE: To delineate the role of Sphingolipids (SPLs) in the human cornea and their cross-talks with transforming growth factor beta (TGF-β) in order to develop novel, non-invasive therapies. METHODS: Human corneal fibroblasts (HCFs) were harvested from healthy donors, stimulated with Vitamin C to promote extracellular matrix assembly, treated with exogenous sphingosine-1-phosphate (S1P) or sphingosine kinase inhibitor 2 (SPHK I2) and isolated after 4 weeks for further analysis...
2017: PloS One
https://www.readbyqxmd.com/read/28806698/fluorescence-and-electron-paramagnetic-resonance-studies-of-norfloxacin-and-n-donor-mixed-ligand-ternary-copper-ii-complexes-stability-and-interaction-with-sds-micelles
#3
Gabriel S Vignoli Muniz, Jimmy Llontop Incio, Odivaldo C Alves, Klaus Krambrock, Letícia R Teixeira, Sonia R W Louro
The stability of ternary copper(II) complexes of a heterocyclic ligand, L (L being 2,2'-bipyridine (bipy) or 1,10-phenanthroline (phen)) and the fluorescent antibacterial agent norfloxacin (NFX) as the second ligand was studied at pH7.4 and different ionic strengths. Fluorescence quenching upon titration of NFX with the binary complexes allowed to obtain stability constants for NFX binding, Kb, as a function of ionic strength. The Kb values vary by more than two orders of magnitude when buffer concentration varies from 0...
August 5, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28806643/mixed-ligand-aroylhydrazone-and-n-donor-heterocyclic-lewis-base-cu-ii-complexes-as-potential-antiproliferative-agents
#4
Manas Sutradhar, Rajeshwari, Tannistha Roy Barman, Alexandra R Fernandes, Fabiana Paradinha, Catarina Roma-Rodrigues, M Fátima C Guedes da Silva, Armando J L Pombeiro
A series of four mixed ligand aroylhydrazone and N-donor heterocyclic Lewis base Cu(II) complexes [CuL(X)]2 [L refers to the dianionic form of (5-bromo-2-hydroxybenzylidene)-2-hydroxybenzohydrazide; X=pyrazine (Pz; 1), pyridine (Py; 2), imidazole (Imz; 3) and 3-pyridinecarbonitrile (3-PyCN; 4)] has been synthesized and characterized by elemental analysis, various spectroscopic techniques and X-ray crystallography (for 1, 2 and 4). The antiproliferative effect of complexes 1-4 was examined in 4 human tumor cell lines (ovarian carcinoma (A2780), colorectal carcinoma (HCT116), lung adenocarcinoma (A549) and breast adenocarcinoma (MCF7)) and in normal human primary Fibroblasts...
August 2, 2017: Journal of Inorganic Biochemistry
https://www.readbyqxmd.com/read/28806406/terminal-differentiation-of-t-cells-is-strongly-associated-with-cmv-infection-and-increased-in-hiv-positive-individuals-on-art-and-lifestyle-matched-controls
#5
Thijs Booiman, Ferdinand W Wit, Arginell F Girigorie, Irma Maurer, Davide De Francesco, Caroline A Sabin, Agnes M Harskamp, Maria Prins, Claudio Franceschi, Steven G Deeks, Alan Winston, Peter Reiss, Neeltje A Kootstra
HIV-1-positive individuals on successful antiretroviral therapy (ART) are reported to have higher rates of age-associated non-communicable comorbidities (AANCCs). HIV-associated immune dysfunction has been suggested to contribute to increased AANCC risk. Here we performed a cross-sectional immune phenotype analysis of T cells in ART-treated HIV-1-positive individuals with undetectable vireamia (HIV-positives) and HIV-1-negative individuals (HIV-negatives) over 45 years of age. In addition, two control groups were studied: HIV negative adults selected based on lifestyle and demographic factors (Co-morBidity in Relation to AIDS, or COBRA) and unselected age-matched donors from a blood bank...
2017: PloS One
https://www.readbyqxmd.com/read/28806376/classification-of-the-residual-cranial-defects-and-selection-of-reconstruction-materials
#6
Nanda Kishore Sahoo, Mohan Rangan N, Kapil Tomar, Sudarshan Bhat
The cranial defects are complex in nature and are due to various causes. Therefore, there is a need for a common term of reference to these defects. This requirement stood as a prime reason for proposing a classification system for cranial defects. The classification is based on 2 decades of experience in cranioplasty. This efficient and simple way of representation would fill the existing lacunae for a systematic communication on cranial defects. Over the ages the evolution of reconstruction and grafting had undergone a massive progress...
August 10, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28806291/revisiting-the-abdominal-donor-site-introducing-a-novel-nomenclature-for-autologous-breast-reconstruction
#7
Jason M Weissler, Frank P Albino, Martin J Carney, Liza C Wu
As abdominally-based free flaps for breast reconstruction continue to evolve, significant effort has been invested in minimizing donor-site morbidity. The impact on the donor-site remains a prevailing principle for breast reconstruction, and thus must be adequately reflected when classifying what is left behind following flap harvest. Although successful in describing the type of flap harvested, the existing nomenclature falls short of incorporating certain critical variables, such as degree of muscular preservation, fascial involvement, mesh implantation, and segmental nerve anatomy...
August 3, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28806059/bis-pyrene-doped-cationic-dipeptide-nanoparticles-for-two-photon-activated-photodynamic-therapy
#8
Bingbing Sun, Lei Wang, Qi Li, Ping-Ping He, Huiling Liu, Hao Wang, Yang Yang, Junbai Li
At present, one of main problems for photodynamic therapy (PDT) is how to improve the treatment depth. Two-photon activated (TPA) developed recently provide a possible solution for it. In this work, we report the energy-transferring assembled cationic dipeptide nanoparticles for two-photon activated photodynamic therapy (TPA-PDT). In the nanoparticles, the co-encapsulated two-photon fluorescent dye bis(pyrene) (BP) is an energy donor and a photosensitizer rose bengal (RB) is an acceptor based on an intraparticle fluorescence resonance energy transfer (FRET) mechanism...
August 14, 2017: Biomacromolecules
https://www.readbyqxmd.com/read/28805989/nitroxyl-donors-for-acute-heart-failure-promising-newcomers
#9
EDITORIAL
John Parissis, Vasiliki Bistola, Ignatios Ikonomidis, Filippos Triposkiadis
No abstract text is available yet for this article.
August 14, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28805985/willingness-to-pay-for-antiretroviral-drugs-among-hiv-and-aids-clients-in-south-east-nigeria
#10
Chinyere Mbachu, Chijioke Okoli, Obinna Onwujekwe, Fabian Enabulele
BACKGROUND: The current trend of withdrawal of donor support for HIV/AIDS treatment in Nigeria may require that the cost of antiretroviral drugs be borne in part by infected people and their families. OBJECTIVE: This study was conducted to determine the economic value for free antiretroviral drugs (ARVs) expressed by clients receiving treatment for HIV/AIDS in a tertiary hospital. STUDY METHOD: The contingent valuation method was used to elicit the values attached to free ARVs from people living with HIV/AIDS that were receiving care in a public tertiary hospital in south-east Nigeria...
August 14, 2017: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/28805866/low-spin-m-ii-l-2-and-m-iii-l-2-m-fe-and-co-complexes-of-tridentate-azo-containing-pyridine-pyrazine-amide-ligands-structures-properties-and-redox-potential-correlations
#11
Arunava Sengupta, Amit Rajput, Suman K Barman, Rabindranath Mukherjee
Using deprotonated forms of tridentate azo-containing pyridine-2-/pyrazine-2-carboxamide 2-[N-(2-phenylazo)carbamoyl]-pyridine/pyrazine, seven bis-ligand complexes of Fe(II)/Co(II) and Fe(III)/Co(III) have been synthesized. Molecular structures of six of them reveal that these six-coordinate complexes utilize all available donor sites of the ligands and assume M(II/III)N2(pyridine/pyrazine)N'2(amide)N''2(azo) coordination. Complexes of Fe(II) and Co(III) are diamagnetic and those of Fe(III) and Co(II) are paramagnetic (S = 1/2; room-temperature magnetic data and EPR spectra)...
August 14, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28805819/donor-qubits-in-silicon-electrical-control-of-nuclear-spins
#12
Andrea Morello
No abstract text is available yet for this article.
August 14, 2017: Nature Nanotechnology
https://www.readbyqxmd.com/read/28805818/all-electric-control-of-donor-nuclear-spin-qubits-in-silicon
#13
Anthony J Sigillito, Alexei M Tyryshkin, Thomas Schenkel, Andrew A Houck, Stephen A Lyon
The electronic and nuclear spin degrees of freedom of donor impurities in silicon form ultra-coherent two-level systems that are potentially useful for applications in quantum information and are intrinsically compatible with industrial semiconductor processing. However, because of their smaller gyromagnetic ratios, nuclear spins are more difficult to manipulate than electron spins and are often considered too slow for quantum information processing. Moreover, although alternating current magnetic fields are the most natural choice to drive spin transitions and implement quantum gates, they are difficult to confine spatially to the level of a single donor, thus requiring alternative approaches...
August 14, 2017: Nature Nanotechnology
https://www.readbyqxmd.com/read/28805803/bisphosphoglycerate-mutase-controls-serine-pathway-flux-via-3-phosphoglycerate
#14
Rob C Oslund, Xiaoyang Su, Michael Haugbro, Jung-Min Kee, Mark Esposito, Yael David, Boyuan Wang, Eva Ge, David H Perlman, Yibin Kang, Tom W Muir, Joshua D Rabinowitz
Lower glycolysis involves a series of reversible reactions, which interconvert intermediates that also feed anabolic pathways. 3-phosphoglycerate (3-PG) is an abundant lower glycolytic intermediate that feeds serine biosynthesis via the enzyme phosphoglycerate dehydrogenase, which is genomically amplified in several cancers. Phosphoglycerate mutase 1 (PGAM1) catalyzes the isomerization of 3-PG into the downstream glycolytic intermediate 2-phosphoglycerate (2-PG). PGAM1 needs to be histidine phosphorylated to become catalytically active...
August 7, 2017: Nature Chemical Biology
https://www.readbyqxmd.com/read/28805723/hitting-the-holy-grail-of-hematopoietic-cell-transplantation-with-naive-t-cell-depleted-allografts-graft-engineered-hematopoietic-stem-cell-transplant
#15
Riad El Fakih, Shahrukh K Hashmi
Hematopoietic cell transplant is a potentially curative procedure for many benign and malignant conditions. The efficacy of allogeneic transplant relies in part on the cytotoxicity of the conditioning regimen and the graft versus tumor effect mediated by alloreactive donor T cells; the same cells are also implicated in the development of graft versus host disease (GVHD). Selective identification and depletion of the T cells implicated in GVHD, while preserving the T cells responsible for graft versus tumor effect has been the focus of many research groups in the recent years...
August 14, 2017: Biomedicines
https://www.readbyqxmd.com/read/28805531/fabrication-and-characterization-of-the-porous-duck-s-feet-collagen-sponge-for-wound-healing-applications
#16
Md Tipu Sultan, Ju Yeon Jeong, Ye Bin Seo, Ok Joo Lee, Hyung Woo Ju, Hyun Jung Park, Young Jin Lee, Ji Seung Lee, Soon Hee Kim, Chan Hum Park
There are several artificial dermis commonly use to cover the wound and promote healing. The major goal of wound management is fast and scarless healing. However, there is no ideal skin substitute, that is effective to accelerate wound healing without scar formation. Artificial dermis substitute also has some drawbacks, such as high cost, insufficient available period and donor pathogen infection. To overcome these problems, we developed duck's feet collagen (DFC) sponge as artificial dermal substitutes for the treatment of full-thickness skin defects...
August 14, 2017: Journal of Biomaterials Science. Polymer Edition
https://www.readbyqxmd.com/read/28805478/production-of-platelet-rich-plasma-gel-from-elderly-patients-under-antithrombotic-drugs-perspectives-in-chronic-wounds-care
#17
M Velier, J Magalon, A Daumas, M Cassar, P Francois, A Ghazouane, C Philandrianos, B Bertrand, C Frere, D Bernot, P Villani, F Dignat George, F Sabatier
Platelet-Rich Plasma (PRP) is an autologous biological therapy obtained by centrifuging the patient's own blood to concentrate platelets. The addition of autologous thrombin and calcium chloride to PRP allows the production of a semi-solid form called PRP gel. PRP gel is increasingly used in a variety of tissue defects and predominantly in the management of non-healing chronic wounds. The topical application of PRP gel seems promising due to the capability of platelets to store and secrete growth factors (GF), fibrin and cytokines, which are essentials for wound healing...
August 14, 2017: Platelets
https://www.readbyqxmd.com/read/28805392/photoinduced-ultrafast-charge-transfer-and-charge-migration-in-small-gold-clusters-passivated-by-a-chromophoric-ligand
#18
Valérie Schwanen, Francoise Remacle
Since the development of attopulses, charge migration induced by short optical pulses has been extensively investigated. We report a computational purely electronic dynamical study of ultrafast few fs charge transfer and charge migration in realistic passivated stoichiometric Au11 and Au20 gold nanoclusters functionalized by a bipyridine ligand. We show that a net significant amount of electronic charge (0.1 to 0.4 |e| where |e| is the electron charge) is permanently transferred from the bipyridine chromophore to the gold cluster during the short 5-6 fs UV-VIS strong pulse...
August 14, 2017: Nano Letters
https://www.readbyqxmd.com/read/28805347/bioelectricity-electromicrobiology-and-sustainability
#19
Kenneth H Nealson
Electromicrobiology is the domain of those prokaryotes able to interact with charged electrodes, using them as electron donors and/or electron acceptors. This is performed via a process called extracellular electron transport, in which outer membrane cytochromes are used to oxidize and/or reduce otherwise unavailable insoluble electron acceptors. EET-capable bacteria can thus be used for a variety of purposes, ranging from small power sources, water reclamation, to pollution remediation and electrosynthesis...
August 14, 2017: Microbial Biotechnology
https://www.readbyqxmd.com/read/28805334/2016-european-conference-on-donor-health-and-management
#20
A Ramond, D J Roberts
No abstract text is available yet for this article.
August 2017: Transfusion Medicine
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