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Mild head injury

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https://www.readbyqxmd.com/read/28429236/the-course-of-headache-in-patients-with-moderate-to-severe-headache-due-to-mild-traumatic-brain-injury-a-retrospective-cross-sectional-study
#1
Chang-Ki Hong, Jin-Yang Joo, Yu Shik Shim, Sook Young Sim, Min A Kwon, Yong Bae Kim, Joonho Chung
BACKGROUND: Little is known about the long-term course of headache in patients with moderate-to-severe headache due to traumatic brain injury (TBI). We evaluated the course of headache in patients with moderate-to-severe headache due to mild TBI. METHODS: Since September 2009, patients with TBI prospectively rated their headache using a numeric rating scale (NRS). From the database containing 935 patients with TBI between September 2009 and December 2013, 259 patients were included according to following criteria: (1) newly onset moderate-to-severe headache (NRS ≥ 4) due to head trauma; (2) age ≥ 15 years; (3) Glasgow Coma Scale ≥ 13; (4) transient loss of consciousness ≤ 30 min; and (5) radiographic evaluation, such as computed tomography or magnetic resonance image...
December 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28417146/repeated-mild-traumatic-brain-injury-in-female-rats-increases-lipid-peroxidation-in-neurons
#2
Nathanael J Yates, Stephen Lydiard, Brooke Fehily, Gillian Weir, Aaron Chin, Carole A Bartlett, Jacqueline Alderson, Melinda Fitzgerald
Negative outcomes of mild traumatic brain injury (mTBI) can be exacerbated by repeated insult. Animal models of repeated closed-head mTBI provide the opportunity to define acute pathological mechanisms as the number of mTBI increases. Furthermore, little is known about the effects of mTBI impact site, and how this may affect brain function. We use a closed head, weight drop model of mTBI that allows head movement following impact, in adult female rats to determine the role of the number and location of mTBI on brain pathology and behaviour...
April 17, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28416072/-a-scandinavian-guideline-for-initial-management-of-minimal-mild-and-moderate-head-trauma-in-children
#3
Christina Rosenlund, Christina Engel Høi-Hansen, Kaare Engell Lundstrøm, Alfred Peter Born, Ole Pedersen, Ramona Åstrand
The Scandinavian Neurotrauma Committee has recently published an evidence- and consensus-based guideline for the management of minor and moderate head trauma in children. They aim is to select children for computed tomography (CT) scan, observation or early discharge, with the attempt to reduce the number of CT scans in children without missing any significant intracranial injury in need for treatment. A flow chart of the guidelines and a help sheet has been developed for clinical use. Suggestions for in-hospital observation and parental information are also presented...
April 3, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28415909/detecting-coached-neuropsychological-dysfunction-a-simulation-experiment-regarding-mild-traumatic-brain-injury
#4
Lily Lau, Michael R Basso, Eduardo Estevis, Ashley Miller, Douglas M Whiteside, Dennis Combs, Timothy J Arentsen
OBJECTIVE: Performance validity tests (PVTs) and symptom validity tests (SVTs) are often administered during neuropsychological evaluations. Examinees may be coached to avoid detection by measures of response validity. Relatively little research has evaluated whether graduated levels of coaching has differential effects upon PVT and SVT performance. Accordingly, the present experiment evaluated the effect of graduated levels of coaching upon the classification accuracy of commonly used PVTs and SVTs and the currently accepted criterion of failing two or more PVTs or SVTs...
April 18, 2017: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/28413696/prevalence-of-potential-sports-associated-risk-factors-in-swiss-amyotrophic-lateral-sclerosis-patients
#5
Nina Feddermann-Demont, Astrid Junge, Konrad P Weber, Michael Weller, Jiří Dvořák, Alexander A Tarnutzer
OBJECTIVES: Amyotrophic lateral sclerosis (ALS) has been reported to occur with increased incidence amongst physically active people. The role of extrinsic risk factors as physical activity, head trauma and drug/pesticide-exposure in the pathophysiology of ALS and especially in the context of practising sports remains controversial. MATERIALS AND METHODS: We retrospectively studied exposure to extrinsic factors in 92 ALS patients in the presymptomatic stage. Metabolic equivalents (METs) were calculated and the association of physical activity, drug intake, head trauma and participation in specific sports (football [soccer], ice hockey) with age at symptom-onset was evaluated...
April 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28410792/accuracy-of-pecarn-catch-and-chalice-head-injury-decision-rules-in-children-a-prospective-cohort-study
#6
Franz E Babl, Meredith L Borland, Natalie Phillips, Amit Kochar, Sarah Dalton, Mary McCaskill, John A Cheek, Yuri Gilhotra, Jeremy Furyk, Jocelyn Neutze, Mark D Lyttle, Silvia Bressan, Susan Donath, Charlotte Molesworth, Kim Jachno, Brenton Ward, Amanda Williams, Amy Baylis, Louise Crowe, Ed Oakley, Stuart R Dalziel
BACKGROUND: Clinical decision rules can help to determine the need for CT imaging in children with head injuries. We aimed to validate three clinical decision rules (PECARN, CATCH, and CHALICE) in a large sample of children. METHODS: In this prospective observational study, we included children and adolescents (aged <18 years) with head injuries of any severity who presented to the emergency departments of ten Australian and New Zealand hospitals. We assessed the diagnostic accuracy of PECARN (stratified into children aged <2 years and ≥2 years), CATCH, and CHALICE in predicting each rule-specific outcome measure (clinically important traumatic brain injury [TBI], need for neurological intervention, and clinically significant intracranial injury, respectively)...
April 11, 2017: Lancet
https://www.readbyqxmd.com/read/28404801/serum-neurofilament-light-as-a-biomarker-for-mild-traumatic-brain-injury-in-contact-sports
#7
Pashtun Shahim, Henrik Zetterberg, Yelverton Tegner, Kaj Blennow
OBJECTIVE: To evaluate whether the axonal protein neurofilament light (NFL) in serum is a sensitive biomarker to detect subtle brain injury or concussion in contact sports athletes. METHODS: Two prospective cohort studies involving (1) 14 Swedish amateur boxers who underwent fluid biomarker assessments at 7-10 days after bout and after 3 months of rest from boxing and (2) 35 Swedish professional hockey players who underwent blood biomarker assessment at 1, 12, 36, and 144 hours after concussion and when the players returned to play were performed...
April 12, 2017: Neurology
https://www.readbyqxmd.com/read/28398105/management-of-mild-traumatic-brain-injury-at-the-emergency-department-and-hospital-admission-in-europe-a-survey-of-71-neurotrauma-centers-participating-in-the-center-tbi-study
#8
Kelly A Foks, Maryse C Cnossen, Diederik W J Dippel, Andrew Maas, David Menon, Joukje van der Naalt, Ewout W Steyerberg, Hester Lingsma, Suzanne Polinder
Previous studies have indicated that there is no consensus about management of mild traumatic brain injury (mTBI) at the emergency department (ED) and during hospital admission. We aim to study variability between management policies for TBI patients at the ED and hospital ward across Europe. Centers participating in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study received questionnaires about different phases of TBI care. These questionnaires included 71 questions about TBI management at the ED and at the hospital ward...
April 11, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28395008/derivation-and-validation-of-a-serum-biomarker-panel-to-identify-infants-with-acute-intracranial-hemorrhage
#9
Rachel Pardes Berger, Brian J Pak, Mariya D Kolesnikova, Janet Fromkin, Richard Saladino, Bruce E Herman, Mary Clyde Pierce, David Englert, Paul T Smith, Patrick M Kochanek
Importance: Abusive head trauma is the leading cause of death from physical abuse. Missing the diagnosis of abusive head trauma, particularly in its mild form, is common and contributes to increased morbidity and mortality. Serum biomarkers may have potential as quantitative point-of-care screening tools to alert physicians to the possibility of intracranial hemorrhage. Objective: To identify and validate a set of biomarkers that could be the basis of a multivariable model to identify intracranial hemorrhage in well-appearing infants using the Ziplex System...
April 10, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28393708/minor-head-trauma-in-the-pediatric-emergency-department-decision-making-nodes
#10
Mario Mastrangelo, Fabio Midulla
BACKGROUND: Minor head trauma is one of the leading cause of access to pediatric emergency departments with only a limited quote of patients resulting in clinically relevant brain injuries. OBJECTIVES: The aim of this review is to guide physicians involved in the management of pediatric head trauma towards a correct clinical approach. METHODS: A Pubmed/Medline search was realized through different entries including "minor head trauma" or "mild head trauma", "minor head injury" or "mild head injury", "acute head trauma"...
April 4, 2017: Current Pediatric Reviews
https://www.readbyqxmd.com/read/28387644/medical-necessity-of-routine-admission-of-children-with-mild-traumatic-brain-injury-to-the-intensive-care-unit
#11
Jared D Ament, Krista N Greenan, Patrick Tertulien, Joseph M Galante, Daniel K Nishijima, Marike Zwienenberg
OBJECTIVE Approximately 475,000 children are treated for traumatic brain injury (TBI) in the US each year; most are classified as mild TBI (Glasgow Coma Scale [GCS] Score 13-15). Patients with positive findings on head CT, defined as either intracranial hemorrhage or skull fracture, regardless of severity, are often transferred to tertiary care centers for intensive care unit (ICU) monitoring. This practice creates a significant burden on the health care system. The purpose of this investigation was to derive a clinical decision rule (CDR) to determine which children can safely avoid ICU care...
April 7, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28387556/long-term-cognitive-and-neuropsychiatric-consequences-of-repetitive-concussion-and-head-impact-exposure
#12
Thomas McAllister, Michael McCrea
Initially, interest in sport-related concussion arose from the premise that the study of athletes engaged in sports associated with high rates of concussion could provide insight into the mechanisms, phenomenology, and recovery from mild traumatic brain injury. Over the last decade, concerns have focused on the possibility that, for some athletes, repetitive concussions may raise the long-term risk for cognitive decline, neurobehavioral changes, and neurodegenerative disease. First conceptualized as a discrete event with variable recovery trajectories, concussion is now viewed by some as a trigger of neurobiological events that may influence neurobehavioral function over the course of the life span...
March 2017: Journal of Athletic Training
https://www.readbyqxmd.com/read/28384927/inflammation-and-outcome-in-traumatic-brain-injury-does-gender-effect-on-survival-and-prognosis
#13
Taraneh Naghibi, Mina Mohajeri, Faramarz Dobakhti
INTRODUCTION: Traumatic Brain Injury (TBI) accounts for the majority of trauma deaths and there has been increased interest in the understanding the role of prognostic factors. C-Reactive Protein (CRP) level increases rapidly in response to trauma. AIM: Aim of the present study was to indicate the role of CRP as a predictor of outcome in TBI patients based on their gender category. MATERIALS AND METHODS: A prospective cohort study in a surgical Intensive Care Unit (ICU) in one of the Zanjan University of Medical Science hospital was designed...
February 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28381654/disorder-of-executive-function-of-the-brain-after-head-injury-and-mild-traumatic-brain-injury-neuroimaging-and-diagnostic-criteria-for-implementation-of-administrative-support-in-japan
#14
Jun Shinoda, Yoshitaka Asano
The diagnotic criteria for disorder of the executive function of the brain (DEFB) as a syndrome of sequela were administratively established (ad-DEFB) in Japan in 2006 to support disabled patients whose impairment, limited to cognition (memory, attention, execution, and behavior), emerges after organic brain injuries regardless of physical deficits. However, some patients suffering from traumatic brain injury (TBI) have been excluded from receiving medico-social services. In particular, this tendency is more prominent in patients with mild TBI because no lesions are apparent on conventional computed tomography (CT) or magnetic resonance imaging (MRI) in the chronic phase...
April 6, 2017: Neurologia Medico-chirurgica
https://www.readbyqxmd.com/read/28377252/impact-of-increased-football-field-width-on-player-high-speed-collision-rate
#15
Jacob R Joseph, Siri S Khalsa, Brandon W Smith, Paul Park
BACKGROUND: High-acceleration head impact is a known risk for mild traumatic brain injury (mTBI) based on studies using helmet accelerometry. In football, offensive and defensive players are at higher risk of mTBI due to increased speed of play. Other collision sport studies suggest that increased playing surface size may contribute to reductions in high-speed collisions. We hypothesized that wider football fields lead to a decreased rate of high-speed collisions. METHODS: Computer football game simulation was developed using MATLAB...
April 1, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28376701/mild-and-mild-to-moderate-traumatic-brain-injury-tbi-induced-significant-progressive-and-enduring-multiple-comorbidities
#16
Jiamei Hou, Rachel Nelson, Zachary Wilkie, Golam Mustafa, Shigeharu Tsuda, Floyd J Thompson, Prodip K Bose
Traumatic brain injury (TBI) can produce life-long disabilities including anxiety, cognitive, balance, and motor deficits. The experimental model of closed head TBI (cTBI) induced by weight drop / impact acceleration is known to produce hallmark TBI injuries. However, comprehensive long-term characterization of co-morbidities induced by graded mild to mild/moderate intensities using this experimental cTBI model has not been reported. The present study used two intensities of weight drop (1.0 m and 1.25 m/450 g) to produce cTBI in a rat model to investigate initial and long-term disability of four comorbidities: anxiety, cognitive, vestibulomotor, and spinal reflex that related to spasticity...
April 4, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28365744/normative-data-for-a-comprehensive-neuropsychological-test-battery-used-in-the-assessment-of-sports-related-concussion
#17
Victoria C Merritt, Jessica E Meyer, Margaret H Cadden, Cristina A F Roman, Dede M Ukueberuwa, Michael D Shapiro, Peter A Arnett
Objective: The use of normative data is a hallmark of the neuropsychological assessment process. Within the context of sports-related concussion, utilizing normative data is especially essential when individualized baseline data are unavailable for comparison. The primary purpose of this study was to establish normative data for a comprehensive neuropsychological test battery used in the assessment of sports-related concussion. A secondary aim was to provide normative data for pertinent demographic variables relevant to the assessment of college athletes, including sex, previous head injuries (PHI), and history of attention deficit hyperactivity disorder (ADHD)/learning disability (LD)...
March 1, 2017: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/28358277/evaluation-of-head-and-brain-injury-risk-functions-using-sub-injurious-human-volunteer-data
#18
Erin J Sanchez, Lee F Gabler, James S McGhee, Ardyn V Olszko, Valeta Carol Chancey, Jeff Crandall, Matthew B Panzer
Risk assessment models are developed to estimate the probability of brain injury during head impact using mechanical response variables such as head kinematics and brain tissue deformation. Existing injury risk functions have been developed using different datasets based on human volunteer and scaled animal injury responses to impact. However, many of these functions have not been independently evaluated with respect to laboratory-controlled human response data. In this study, the specificity of fourteen existing brain injury risk functions was assessed by evaluating their ability to correctly predict non-injurious response using previously conducted sled tests with well-instrumented human research volunteers...
March 30, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28347679/chronic-traumatic-encephalopathy-the-cellular-sequela-to-repetitive-brain-injury
#19
REVIEW
Alexander R Vile, Leigh Atkinson
This review aims to integrate current literature on the pathogenic mechanisms of Chronic Traumatic Encephalopathy (CTE) to create a multifactorial understanding of the disease. CTE is a progressive neurodegenerative disease, classed as a tauopathy, although it appears the pathogenic mechanisms are more complex than this. It affects those with a history of repetitive mild traumatic brain injury. Currently, there are no treatments for CTE and the disease can only be affirmatively diagnosed in post mortem. Understanding the pathogenesis of the disease will provide an avenue to explore possible treatment and diagnostic modalities...
March 24, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28343797/early-brain-edema-is-a-predictor-of-in-hospital-mortality-in-traumatic-brain-injury
#20
Brian Tucker, Jill Aston, Megan Dines, Elena Caraman, Marianne Yacyshyn, Mary McCarthy, James E Olson
BACKGROUND: Identifying patients who may progress to a poor clinical outcome will encourage earlier appropriate therapeutic interventions. Brain edema may contribute to secondary injury in traumatic brain injury (TBI) and thus, may be a useful prognostic indicator. OBJECTIVE: We determined whether the presence of brain edema on the initial computed tomography (CT) scan of TBI patients would predict poor in-hospital outcome. METHODS: We performed a retrospective review of all trauma patients with nonpenetrating head trauma at a Level I Trauma Center...
March 23, 2017: Journal of Emergency Medicine
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