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https://www.readbyqxmd.com/read/28432421/the-effect-of-nitric-oxide-synthase-inhibition-with-and-without-inhibition-of-prostaglandins-on-blood-flow-in-different-human-skeletal-muscles
#1
Ilkka Heinonen, Bengt Saltin, Ylva Hellsten, Kari K Kalliokoski
PURPOSE: Animal studies suggest that the inhibition of nitric oxide synthase (NOS) affects blood flow differently in different skeletal muscles according to their muscle fibre type composition (oxidative vs glycolytic). Quadriceps femoris (QF) muscle consists of four different muscle parts: vastus intermedius (VI), rectus femoris (RF), vastus medialis (VM), and vastus lateralis (VL) of which VI is located deep within the muscle group and is generally regarded to consist mostly of oxidative muscle fibres...
April 21, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28427422/differences-in-muscle-activity-and-temporal-step-parameters-between-lokomat-guided-walking-and-treadmill-walking-in-post-stroke-hemiparetic-patients-and-healthy-walkers
#2
Klaske van Kammen, Anne M Boonstra, Lucas H V van der Woude, Heleen A Reinders-Messelink, Rob den Otter
BACKGROUND: The Lokomat is a robotic exoskeleton that can be used to train gait function in hemiparetic stroke. To purposefully employ the Lokomat for training, it is important to understand (1) how Lokomat guided walking affects muscle activity following stroke and how these effects differ between patients and healthy walkers, (2) how abnormalities in the muscle activity of patients are modulated through Lokomat guided gait, and (3) how temporal step characteristics of patients were modulated during Lokomat guided walking...
April 20, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28427290/a-real-time-method-for-decoding-the-neural-drive-to-muscles-using-single-channel-intra-muscular-emg-recordings
#3
Saeed Karimimehr, Hamid Reza Marateb, Silvia Muceli, Marjan Mansourian, Miguel Angel Mañanas, Dario Farina
The neural command from motor neurons to muscles - sometimes referred to as the neural drive to muscle - can be identified by decomposition of electromyographic (EMG) signals. This approach can be used for inferring the voluntary commands in neural interfaces in patients with limb amputations. This paper proposes for the first time an innovative method for fully automatic and real-time intramuscular EMG (iEMG) decomposition. The method is based on online single-pass density-based clustering and adaptive classification of bivariate features, using the concept of potential measure...
March 20, 2017: International Journal of Neural Systems
https://www.readbyqxmd.com/read/28426509/log-transformed-emg-amplitude-power-output-relationship-single-leg-knee-extensor-versus-single-leg-cycle-ergometry
#4
Eric B Noble, Joshua M Pilarski, Harshal K Vora, Jorge M Zuniga, Moh H Malek
Comparing and contrasting motor unit recruitment and activation for the same muscles for multiple versus single-joint exercise may provide a better understanding of neuromuscular fatigue. The purpose of this study, therefore, is to compare the slope and y-intercept terms for the three superficial quadriceps femoris (vastus lateralis, rectus femoris, and vastus medialis) muscles derived from the log-transformed EMG amplitude-power output relationship between the single-leg knee-extensor ergometry and the single-leg cycle ergometry...
April 15, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28423987/reproducibility-of-upper-leg-emg-frequency-content-during-cycling
#5
Rodrigo Rico Bini, Camila Peter Hoefelmann, Vitor Pereira Costa, Fernando Diefenthaeler
Reproducibility of frequency content from surface electromyography (sEMG) signals has not been assessed and it is unknown if incremental load testing design could affect sEMG in cycling. The goals of this study were to assess the reproducibility of measures from sEMG frequency content between sessions and to compare these frequency components between a ramp and a step incremental cycling test. Eighteen cyclists performed four incremental load cycling tests to exhaustion. Two tests were performed using a step increment (load started at 100 W for 3 min followed by increments of 30 W every 3 min) and two were performed using a ramp increment (load started at 100 W for 1 min followed by increments of 30 W·min(-1))...
April 20, 2017: Journal of Sports Sciences
https://www.readbyqxmd.com/read/28422559/the-influence-of-ambulatory-aid-on-lower-extremity-muscle-activation-during-gait
#6
Michael Sanders, Anton E Bowden, Spencer Baker, Ryan Jensen, McKenzie Nichols
CONTEXT: Foot and ankle injuries are common, and often require a non-weight bearing period of immobilization for the involved leg. This non-weight bearing period usually results in muscle atrophy for the involved leg. There is a dearth of objective data describing muscle activation for different ambulatory aids that are used during the aforementioned non-weight bearing period. OBJECTIVE: To compare activation amplitudes for four leg muscles during (1) able-bodied gait and (2) ambulation involving three different ambulatory aids that can be used during the acute phase of foot and ankle injury care...
April 19, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28417049/morphometric-study-of-tensor-of-vastus-intermedius-in-south-indian-population
#7
Raveendranath Veeramani, Dhivyalakshmi Gnanasekaran
Tensor of vastus intermedius is a newly discovered muscle located between vastus lateralis and vastus intermedius. The purpose of this study was to investigate the detailed morphology of tensor of vastus intermedius, specifically to provide data pertaining to the attachments, innervations, variation in the types and its morphometry in South Indian population. The tensor of vastus intermedius was studied in thirty six cadaveric lower limbs using macrodissection techniques. The origin of the muscle was from upper part of intertrochanteric line and anterior part of greater trochanter of femur inserted to medial aspect of upper border of patella...
March 2017: Anatomy & Cell Biology
https://www.readbyqxmd.com/read/28416354/unilateral-jumps-in-different-directions-a-novel-assessment-of-soccer-associated-power
#8
Conall F Murtagh, Jos Vanrenterghem, Andrew O'Boyle, Ryland Morgans, Barry Drust, Robert M Erskine
OBJECTIVES: We aimed to determine whether countermovement jumps (CMJs; unilateral and bilateral) performed in different directions assessed independent lower-limb power qualities, and if unilateral CMJs would better differentiate between elite and non-elite soccer players than the bilateral vertical (BV) CMJ. DESIGN: Elite (n=23; age, 18.1±1.0years) and non-elite (n=20; age, 22.3±2.7years) soccer players performed three BV, unilateral vertical (UV), unilateral horizontal-forward (UH) and unilateral medial (UM) CMJs...
March 29, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28414877/accelerated-point-of-muscle-deoxygenation-during-the-20-m-shuttle-run-test
#9
Daisuke Kume, Akira Iguchi, Hiroshi Endoh
This study examined whether the point of accelerated deoxygenation of active muscle occurs during the 20-m shuttle run test (20mSRT) and, if so, whether it is associated with exercise performance in the test. Twenty-nine male subjects performed the 20mSRT, and concentration changes in oxyhaemoglobin (ΔOxy-Hb) and deoxyhaemoglobin (ΔDeoxy-Hb) in the m. vastus lateralis were measured using a portable near-infrared spectroscopy device. The difference between the relative concentration changes in ΔOxy-Hb and ΔDeoxy-Hb (Δ[Oxy-Hb - Deoxy-Hb]) was regarded as the muscle oxygenation index...
April 16, 2017: Clinical Physiology and Functional Imaging
https://www.readbyqxmd.com/read/28411486/the-effect-of-age-and-knee-osteoarthritis-on-muscle-activation-patterns-and-knee-joint-biomechanics-during-dual-belt-treadmill-gait
#10
Derek Rutherford, Matthew Baker, Ivan Wong, William Stanish
PURPOSE: To compare a group of individuals with moderate medial compartment knee osteoarthritis (OA) to both an age-matched asymptomatic group of older adults and younger adults to determine whether differences in knee joint muscle activation patterns and joint biomechanics exist during gait between these three groups. SCOPE: 20 young adults, 20 older adults, and 40 individuals with moderate knee OA were recruited. Using standardized procedures, surface electromyograms were recorded from the vastus lateralis and medialis, rectus femoris and the medial and lateral hamstrings...
April 7, 2017: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/28411009/skeletal-muscle-morphology-and-regulatory-signalling-in-endurance-trained-and-sedentary-individuals-the-influence-of-ageing
#11
U R Mikkelsen, J Agergaard, C Couppé, J F Grosset, A Karlsen, S P Magnusson, P Schjerling, M Kjaer, A L Mackey
Muscle mass in humans is inversely associated with circulating levels of inflammatory cytokines, but the interaction between ageing and training on muscle composition and the intra-muscular signalling behind inflammation and contractile protein synthesis and degradation is unknown. We studied 15 healthy life-long endurance runners, 12 age-matched untrained controls, 10 young trained and 12 young untrained individuals. Thigh muscle composition was investigated by magnetic resonance imaging (MRI), where non-contractile intramuscular tissue (NCIT) area (fat and connective tissue) was found to be greater in older but lower in trained individuals...
April 11, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28406926/high-resolution-respirometry-of-fine-needle-muscle-biopsies-in-pre-manifest-huntington-s-disease-expansion-mutation-carriers-shows-normal-mitochondrial-respiratory-function
#12
Eva Buck, Martina Zügel, Uwe Schumann, Tamara Merz, Anja M Gumpp, Anke Witting, Jürgen M Steinacker, G Bernhard Landwehrmeyer, Patrick Weydt, Enrico Calzia, Katrin S Lindenberg
Alterations in mitochondrial respiration are an important hallmark of Huntington's disease (HD), one of the most common monogenetic causes of neurodegeneration. The ubiquitous expression of the disease causing mutant huntingtin gene raises the prospect that mitochondrial respiratory deficits can be detected in skeletal muscle. While this tissue is readily accessible in humans, transgenic animal models offer the opportunity to cross-validate findings and allow for comparisons across organs, including the brain...
2017: PloS One
https://www.readbyqxmd.com/read/28398950/a-ketone-ester-drink-increases-postexercise-muscle-glycogen-synthesis-in-humans
#13
David A Holdsworth, Peter J Cox, Tom Kirk, Huw Stradling, Samuel G Impey, Kieran Clarke
INTRODUCTION: Physical endurance can be limited by muscle glycogen stores, in that glycogen depletion markedly reduces external work. During carbohydrate restriction, the liver synthesises the ketone bodies, D-β-hydroxybutyrate and acetoacetate, from fatty acids. In animals and in the presence of glucose, D-β-hydroxybutyrate promotes insulin secretion and increases glycogen synthesis. Here we determined whether a dietary ketone ester, combined with plentiful glucose, can increase post-exercise glycogen synthesis in human skeletal muscle...
April 10, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28398573/skeletal-muscle-pgc1%C3%AE-1-nucleosome-position-and-260nt-dna-methylation-determine-exercise-response-and-prevent-ectopic-lipid-accumulation-in-men
#14
Sudip Bajpeyi, Jeffrey D Covington, Erin M Taylor, Laura K Stewart, Jose E Galgani, Tara M Henagan
Endurance exercise has been shown to improve lipid oxidation and increase mitochondrial content in skeletal muscle: two features that have shown dependence on increased expression of the PPAR gamma co-activator 1 alpha (PGC1α). It is also hypothesized that exercise related alterations in PGC1α expression occur through epigenetic regulation of nucleosome positioning in association with differential DNA methylation status within the PCG1α promoter. Here we show that when primary human myotubes from obese, type 2 diabetics are exposed to lipolytic stimulus (PFI) in vitro, nucleosome occupancy surrounding the -260 nucleotide (nt) region, a known regulatory DNA methylation site, is reduced...
April 10, 2017: Endocrinology
https://www.readbyqxmd.com/read/28394829/electromyographical-comparison-of-muscle-activation-patterns-across-three-commonly-performed-kettlebell-exercises
#15
Brian C Lyons, Jerry J Mayo, W Steve Tucker, Ben Wax, Russell C Hendrix
The purpose of this study was to compare the muscle activation patterns of three different kettlebell (KB) exercises using electromyography (EMG). Fourteen resistance-trained subjects completed a one-arm swing (Swing), one-arm swing style snatch (Snatch), and a one-arm clean (Clean) using a self-selected 8-10 RM load for each exercise. Trial sessions consisted of subjects performing 5 repetitions of each kettlebell exercise. Mean EMG was used to assess the muscle activation of the biceps brachii (BB), anterior deltoid (AD), posterior deltoid (PD), erector spinae (ES), vastus lateralis (VL), biceps femoris (BF), contralateral external oblique (EO), and gluteus maximus (GM) during each lift using surface electrodes...
December 20, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28394459/ergogenic-properties-of-metformin-in-simulated-high-altitude
#16
Rebecca L Scalzo, Hunter L Paris, Scott E Binns, Janelle L Davis, Joseph W Beals, Christopher L Melby, Gary J Luckasen, Matthew S Hickey, Benjamin F Miller, Karyn L Hamilton, Christopher Bell
Metformin augments glucose/glycogen regulation and may acutely promote fatigue resistance during high-intensity exercise. In hypobaric environments, such as high altitude, the important contribution of carbohydrates to physiological function is accentuated as glucose/glycogen dependence is increased. Because hypoxia/hypobaria decreases insulin sensitivity, replenishing skeletal muscle glycogen in high altitude becomes challenging and subsequent physical performance may be compromised. We hypothesized that in conditions where glycogen repletion was critical to physical outcomes, metformin would attenuate hypoxia-mediated decrements in exercise performance...
April 10, 2017: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/28393459/lunhab-interactive-effects-of-a-10-day-sustained-exposure-to-hypoxia-and-bedrest-on-aerobic-exercise-capacity-in-male-lowlanders
#17
Michail E Keramidas, Igor B Mekjavic, Ola Eiken
The study examined the interactive effects of a 10-day exposure to hypoxia and bedrest on the whole body peak oxygen uptake (V˙O2 peak ) during maximal exercise, and on skeletal-muscle and cerebral oxygenation during submaximal exercise. Nine males underwent three 10-day confinements, in a Latin-square order: (i) a normoxic bedrest [NBR; partial pressure of inspired O2 (PI O2 ) = 134.2 ± 0.7 mmHg], (ii) a hypoxic bedrest (HBR; PI O2  = 102.9 ± 0.1 mmHg at day 1, 91.5 ± 1.2 mmHg at days 3-10), and (iii) a hypoxic ambulation (HAMB; PI O2 as in HBR)...
April 9, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/28385562/shoe-cushioning-reduces-impact-and-muscle-activation-during-landings-from-unexpected-but-not-self-initiated-drops
#18
Weijie Fu, Ying Fang, Yaodong Gu, Lingyan Huang, Li Li, Yu Liu
OBJECTIVES: To date, few rigorous scientific studies have been conducted to understand the impact mechanics and muscle activation characteristics of different landing tasks and the influence of shoe properties. The aim of this study was to examine the effects of shoe cushioning on impact biomechanics and muscular responses during drop landings. DESIGN: A single-blinded and randomized design. METHODS: Twelve male collegiate basketball players performed bipedal landings from self-initiated and unexpected drops (SIDL and UDL) from a 60-cm height wearing highly-cushioned basketball shoes (Bball) and less cushioned control shoes (CC)...
March 21, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28384286/t-t-homozygosity-of-the-tenascin-c-gene-polymorphism-rs2104772-negatively-influences-exercise-induced-angiogenesis
#19
Paola Valdivieso, Marco Toigo, Hans Hoppeler, Martin Flück
BACKGROUND: Mechanical stress, including blood pressure related factors, up-regulate expression of the pro-angiogenic extracellular matrix protein tenascin-C in skeletal muscle. We hypothesized that increased capillarization of skeletal muscle with the repeated augmentation in perfusion during endurance training is associated with blood vessel-related expression of tenascin-C and would be affected by the single-nucleotide polymorphism (SNP) rs2104772, which characterizes the non-synonymous exchange of thymidine (T)-to-adenosine (A) in the amino acid codon 1677 of tenascin-C...
2017: PloS One
https://www.readbyqxmd.com/read/28378501/acl-reconstruction-does-not-induce-further-gamma-loop-abnormalities-on-the-intact-side-of-the-qf-a-longitudinal-study
#20
Yu Konishi
This study aimed to investigate the effect of surgery on the gamma-loop of the quadriceps on the side with an intact knee in patients with ACL injuries. We compared longitudinally the response of alpha motor neurons to vibration stimulation of the quadriceps on the side with an intact knee before and after ACL reconstruction. To evaluate alpha motor neuron response, we measured the maximal knee extension strength and integrated electromyography of the vastus medialis, vastus lateralis, and rectus femoris. After obtaining pre-vibration data from each subject, vibration stimulation was applied to the infrapatellar tendon, and the same measurements were performed immediately after stimulation...
April 4, 2017: Scandinavian Journal of Medicine & Science in Sports
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