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https://www.readbyqxmd.com/read/28340134/primary-motor-cortex-organization-is-altered-in-persistent-patellofemoral-pain
#1
Maxine Te, Abrahão F Baptista, Lucy S Chipchase, Siobhan M Schabrun
Objective.:  Reorganization of the primary motor cortex (M1) may be a feature of persistent patellofemoral pain (PFP), but no studies have investigated M1 organization in this condition. Here we aimed to examine the organization of the M1 representation of the quadriceps muscles in people with PFP and healthy controls. Design.:  Using a cross-sectional design, the M1 representation of the rectus femoris, vastus lateralis, and vastus medialis was mapped using transcranial magnetic stimulation in 11 individuals with PFP and 11 controls...
March 14, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28336535/the-effects-of-short-work-versus-longer-work-periods-within-intermittent-exercise-on-v%C3%AC-o2p-kinetics-muscle-deoxygenation-and-energy-system-contribution
#2
Michael Christopher McCrudden, Daniel A Keir, Glen R Belfry
We examined the effects of inserting 3 s recovery periods during high-intensity cycling exercise at 25 s and 10 s intervals on pulmonary oxygen uptake (V̇O2p), muscle deoxygenation (HHb), associated kinetics (τ), and energy system contributions. Eleven men (24±3 years) completed two trials of three cycling protocols: an 8 min continuous protocol (CONT) and two, 8 min intermittent exercise protocols with work-to-rest periods of 25 s-to-3 s (25INT) and 10 s-to-3 s (10INT). Each protocol began with a step-transition from a 20 W baseline to a power output (PO) of 60% between lactate threshold and maximal V̇O2p (Δ60)...
March 23, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28336251/distal-extension-of-the-anterior-approach-to-the-hip-using-the-femoral-interbundle-technique-surgical-technique-and-case-series
#3
Stijn G M Ghijselings, Ronald Driesen, Jean-Pierre Simon, Kristoff Corten
BACKGROUND: The direct anterior approach (DAA) is becoming more popular as the standard surgical approach for primary total hip arthroplasty. However, it has been associated with an increased incidence of intraoperative femoral fractures in particular during the learning curve. Distal extension of the approach may be needed in case of intraoperative complications. The aim of the present study is to describe the distal extension of the DAA using the femoral interbundle technique. METHODS: A stepwise approach based on a cadaveric study to extend the DAA distally is presented...
February 24, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28329045/extensive-type-ii-muscle-fiber-atrophy-in-elderly-female-hip-fracture-patients
#4
Irene Fleur Kramer, Tim Snijders, Joey S J Smeets, Marika Leenders, Janneau van Kranenburg, Marcel den Hoed, Lex B Verdijk, Martijn Poeze, Luc J C van Loon
Background: Sarcopenia, or the loss of muscle mass and strength, is known to increase the risk for falls and (hip) fractures in older people. The objective of this study was to assess the skeletal muscle fiber characteristics in elderly female hip fracture patients. Method: Percutaneous needle biopsies were collected from the vastus lateralis muscle in 15 healthy young women (20 ± 0.4 years), 15 healthy elderly women (79 ± 1.7 years), and 15 elderly women with a fall-related hip fracture (82 ± 1...
January 20, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28325123/effect-of-stimulation-of-cold-receptors-with-menthol-on-emg-activity-of-quadriceps-muscle-during-low-load-contraction
#5
Tadayuki Tokunaga, Hitoshi Sugawara, Chigaya Tadano, Masuo Muro
PURPOSE: Facilitatory and inhibitory responses of spinal motor neurons are influenced by somatosensory input from the skin. The purpose of this study, employing electromyography, was to examine the neuromuscular changes that occur with menthol applied to the skin over the quadriceps muscle. METHODS: Forty-two healthy volunteers performed isometric knee extensions at 35% maximum voluntary contraction (MVC) in three groups (Adult Placebo, Adult Menthol, Older Adult Menthol)...
March 21, 2017: Somatosensory & Motor Research
https://www.readbyqxmd.com/read/28325029/noninvasive-eeg-correlates-of-overground-and-stair-walking
#6
Justin A Brantley, Trieu Phat Luu, Recep Ozdemir, Fangshi Zhu, Anna T Winslow, Helen Huang, Jose L Contreras-Vidal
Automated walking intention detection remains a challenge in lower-limb neuroprosthetic systems. Here, we assess the feasibility of extracting motor intent from scalp electroencephalography (EEG). First, we evaluated the corticomuscular coherence between central EEG electrodes (C1, Cz, C2) and muscles of the shank and thigh during walking on level ground and stairs. Second, we trained decoders to predict the linear envelope of the surface electromyogram (EMG). We observed significant EEG-led corticomuscular coupling between electrodes and sEMG (tibialis anterior) in the high delta (3-4 Hz) and low theta (4-5 Hz) frequency bands during level walking, indicating efferent signaling from the cortex to peripheral motor neurons...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324994/co-activation-periods-of-gastrocnemius-and-vastus-lateralis-during-walking-evaluated-by-surface-electromyography
#7
Alessandro Mengarelli, Annachiara Strazza, Agnese Sbrollini, Angela Agostinelli, Laura Burattini, Sandro Fioretti, Francesco Di Nardo
"In vivo" studies reported that the co-activation of gastrocnemius and quadriceps femoris (QF) muscles produces ACL strain values greater than those caused by an isolated activation of either muscle. Aim of this study was to assess the co-activation of gastrocnemius (lateral head, GL) and vastus lateralis (VL) in healthy and young adults during walking. To this purpose the Statistical Gait Analysis was performed, that allows a characterization of gait considering hundreds of strides belonging to the same walking trial...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324993/dynamic-knee-muscle-co-contraction-quantified-during-walking
#8
Annachiara Strazza, Alessandro Mengarelli, Valentina Agostini, Marco Knaflitz, Laura Burattini, Sandro Fioretti, Francesco Di Nardo
The purpose of the present study was the quantification of the co-activation patterns of the knee extensor and flexor muscles during walking at self-selected speed and cadence. To this aim, the Statistical Gait Analysis, a recent methodology providing a statistical characterization of gait, was performed on surface EMG signals from Vastus Lateralis (VL) and Medial Hamstrings (MH) in 14 healthy young adult subjects. Muscular co-contraction was assessed as the overlapping period between activation intervals of agonist and antagonist muscles...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28321925/effects-of-6-months-aerobic-interval-training-on-skeletal-muscle-metabolism-in-middle-aged-metabolic-syndrome-patients
#9
A Guadalupe-Grau, V E Fernández-Elías, J F Ortega, F Dela, J W Helge, R Mora Rodríguez
AIM: Aerobic interval training (AIT) improves the health of metabolic syndrome patients (MetS) more than moderate intensity continuous training. However, AIT has not been shown to reverse all metabolic syndrome risk factors, possibly due to the limited duration of the training programs. PURPOSE: To assess the effects of 6 months of AIT on cardio-metabolic health and muscle metabolism in middle aged MetS. METHODS: Eleven MetS (54.5 ± 0.7 yrs old) underwent 6 month of 3 days a week supervised AIT program on a cycle-ergometer...
March 21, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28314055/localization-of-muscle-damage-within-the-quadriceps-femoris-induced-by-different-types-of-eccentric-exercises
#10
Sumiaki Maeo, Akira Saito, Shun Otsuka, Xiyao Shan, Hiroaki Kanehisa, Yasuo Kawakami
This study examined localization of muscle damage within the quadriceps femoris induced by different types of eccentric exercises by using transverse relaxation time (T2 )-weighted magnetic resonance imaging (MRI). Thirty-three young males performed either of the following three exercises: single-joint eccentric contraction of the knee extensors (KE), eccentric squat (S), or downhill walking (DW) (n=11/exercise). KE and S consisted of 5-set × 10-lowering of 90% one-repetition maximum load. DW was performed for 60 min with -10% slope, 6 km/h velocity, and 20% body mass load carried...
March 17, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28292829/non-linear-modulation-of-cutaneous-reflexes-with-increasing-speed-of-locomotion-in-spinal-cats
#11
Marie-France Hurteau, Yann Thibaudier, Charline Dambreville, Anass Chraibi, Etienne Desrochers, Alessandro Telonio, Alain Frigon
Cutaneous reflexes are important for rapidly responding to perturbations, correcting limb trajectory and strengthening support. During locomotion, they are modulated by phase to generate functionally appropriate responses. The goal of the present study was to determine if cutaneous reflexes and their phase-dependent modulation are altered with increasing speed and whether this is accomplished at a spinal level. Four adult cats that recovered stable hindlimb locomotion following spinal transection were implanted with electrodes to chronically record hindlimb muscle activity and to electrically stimulate the superficial peroneal nerve to evoke cutaneous reflexes...
March 14, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28290972/malignant-hyperthermia-susceptibility-and-fitness-for-duty
#12
Michael A Lee, Erin B McGlinch, Maria C McGlinch, John F Capacchione
INTRODUCTION: Malignant hyperthermia (MH) is an inherited hypermetabolic condition characterized by uncontrolled calcium release from the sarcoplasmic reticulum of skeletal muscle, usually from exposure to inhaled general anesthetics and/or the depolarizing neuromuscular blocking agent succinylcholine. Multiple case reports now reveal that crises may be precipitated by environmental factors such as exercise or high ambient temperatures. Common signs of an MH crisis include life-threatening hyperthermia, metabolic acidosis, muscle rigidity, and tachycardia...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28290752/mri-based-assessment-of-lower-extremity-muscle-volumes-in-patients-before-and-after-acl-reconstruction
#13
Grant E Norte, Katherine R Knaus, Chris Kuenze, Geoffrey G Handsfield, Craig H Meyer, Silvia S Blemker, Joseph M Hart
CONTEXT: Study of muscle volumes in patients after anterior cruciate ligament (ACL) injury and reconstruction (ACL-R) is largely limited to cross-sectional assessment of the thigh musculature, which may inadequately describe post-traumatic and post-surgical muscle function. No studies have prospectively examined the influence of ACL injury and reconstruction on lower extremity muscle volumes. OBJECTIVE: Assess magnetic resonance imaging (MRI) derived lower extremity muscle volumes, and quantify quadriceps strength and activation in patients following ACL injury and reconstruction...
March 14, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28281651/sprint-interval-but-not-continuous-exercise-increases-pgc-1%C3%AE-protein-content-and-p53-phosphorylation-in-nuclear-fractions-of-human-skeletal-muscle
#14
Cesare Granata, Rodrigo S F Oliveira, Jonathan P Little, Kathrin Renner, David J Bishop
Sprint interval training has been reported to induce similar or greater mitochondrial adaptations to continuous training. However, there is limited knowledge about the effects of different exercise types on the early molecular events regulating mitochondrial biogenesis. Therefore, we compared the effects of continuous and sprint interval exercise on key regulatory proteins linked to mitochondrial biogenesis in subcellular fractions of human skeletal muscle. Nineteen men, performed either 24 min of moderate-intensity continuous cycling at 63% of WPeak (CE), or 4 × 30-s "all-out" cycling sprints (SIE)...
March 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28280974/post-absorptive-muscle-protein-turnover-affects-resistance-training-hypertrophy
#15
Paul T Reidy, Michael S Borack, Melissa M Markofski, Jared M Dickinson, Christopher S Fry, Rachel R Deer, Elena Volpi, Blake B Rasmussen
PURPOSE: Acute bouts of resistance exercise and subsequent training alters protein turnover in skeletal muscle. The mechanisms responsible for the changes in basal post-absorptive protein turnover and its impact on muscle hypertrophy following resistance exercise training are unknown. Our goal was to determine whether post-absorptive muscle protein turnover following 12 weeks of resistance exercise training (RET) plays a role in muscle hypertrophy. In addition, we were interested in determining potential molecular mechanisms responsible for altering post-training muscle protein turnover...
March 9, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28280662/avoiding-facial-incisions-with-midface-free-tissue-transfer
#16
Mark W Stalder, Michael Sosin, Leo J Urbinelli, James L Mayo, Amir H Dorafshar, Hugo St Hilaire, Daniel E Borsuk, Eduardo D Rodriguez
BACKGROUND: We have adopted an intraoral microsurgical anastomosis to the facial vessels to eliminate the need for any visible facial incisions. METHODS: Cadaveric dissection was used to demonstrate accessibility of the facial artery and vein through an intraoral approach. Additionally, 5 patients underwent free tissue transfer for reconstruction of major defects of the midface through an intraoral, transmucosal approach, obviating the need for visible skin incisions...
February 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28273102/age-related-differences-in-skeletal-muscle-microvascular-response-to-exercise-as-detected-by-contrast-enhanced-ultrasound-ceus
#17
Wulf Hildebrandt, Hans Schwarzbach, Anita Pardun, Lena Hannemann, Björn Bogs, Alexander M König, Andreas H Mahnken, Olaf Hildebrandt, Ulrich Koehler, Ralf Kinscherf
BACKGROUND: Aging involves reductions in exercise total limb blood flow and exercise capacity. We hypothesized that this may involve early age-related impairments of skeletal muscle microvascular responsiveness as previously reported for insulin but not for exercise stimuli in humans. METHODS: Using an isometric exercise model, we studied the effect of age on contrast-enhanced ultrasound (CEUS) parameters, i.e. microvascular blood volume (MBV), flow velocity (MFV) and blood flow (MBF) calculated from replenishment of Sonovue contrast-agent microbubbles after their destruction...
2017: PloS One
https://www.readbyqxmd.com/read/28272266/lack-of-activation-of-mitophagy-during-endurance-exercise-in-human
#18
Céline Schwalm, Louise Deldicque, Marc Francaux
PURPOSE: To determine whether fission and mitophagy are activated by acute endurance exercise in human skeletal muscle and to investigate if this activation is dependent upon the nutritional state. METHODS: Trained athletes (n = 7) cycled for 2 h at 70% VO2 peak in a fed or fasted state. Vastus lateralis muscle biopsies were obtained at baseline, before, immediately after and 1 h after exercise. Protein and mRNA markers for mitophagy, mitochondrial biogenesis, fission and fusion were analyzed using qRT-PCR and Western blot...
March 8, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28268272/postural-responses-after-utilization-of-a-computerized-biofeedback-based-intervention-aimed-at-improving-static-and-dynamic-balance-in-traumatic-brain-injury-a-case-study
#19
Rakesh Pilkar, Nibal Arzouni, Arvind Ramanujam, Kathleen Chervin, Karen J Nolan
Balance dysfunction is one of the most disabling aspects of Traumatic Brain Injury (TBI). Without rapid transmission and accurate perception of somatosensory inputs, the automatic postural responses required during standing may be delayed or absent after TBI which can lead to instability. Further, the sensitivity level to which environmental perturbations can be detected is also vital, as the central nervous system will only employ balance control strategies when it perceives a change in equilibrium. Such undetectable perturbations, however small they may be, can result in fatal falls, especially after TBI...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268051/distal-myopathy-with-adssl1-mutations-in-korean-patients
#20
Hyung Jun Park, Ha Young Shin, Sungjun Kim, Se Hoon Kim, Yunbeom Lee, Jung Hwan Lee, Ji-Man Hong, Seung Min Kim, Kee Duk Park, Byung-Ok Choi, Ji Hyun Lee, Young-Chul Choi
To understand the characteristics of ADSSL1 myopathy, we investigated the clinical manifestation in Korean patients with ADSSL1 mutations. We developed a targeted panel of 16 distal-myopathy genes and recruited a total of 12 patients with genetically undetermined distal myopathy. We found four (33%) with ADSSL1 mutations and one (8%) with GNE mutations. ADSSL1 mutations consisted of c.910G>A, c.1048delA and c.1220T>C mutations. Patients with ADSSL1 mutations demonstrated distal muscle weakness in adolescence, followed by quadriceps muscle weakness in the early 30s...
February 14, 2017: Neuromuscular Disorders: NMD
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