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Cardiac scar score

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https://www.readbyqxmd.com/read/29572087/utility-of-dual-source-computed-tomography-in-cardiac-resynchronization-therapy-direct-study
#1
Quynh A Truong, Jackie Szymonifka, Michael H Picard, Wai-Ee Thai, Bryan Wai, Jim W Cheung, E Kevin Heist, Udo Hoffmann, Jagmeet P Singh
BACKGROUND: Dual-source computed tomography (CT) can evaluate left ventricular (LV) dyssynchrony, myocardial scar and coronary venous anatomy in patients undergoing cardiac resynchronization therapy (CRT). OBJECTIVE: We aim to determine if dual-source CT predicts clinical CRT outcomes and reduces intra-procedural time. METHODS: In this prospective study, 54 patients scheduled for CRT (age 63±11, 74% male) underwent pre-procedural CT to assess their venous anatomy as well as CT-derived dyssynchrony metrics and myocardial scar...
March 20, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29447739/native-t1-and-ecv-of-noninfarcted-myocardium-and-outcome-in-patients-with-coronary-artery-disease
#2
Valentina O Puntmann, Gerry Carr-White, Andrew Jabbour, Chung-Yao Yu, Rolf Gebker, Sebastian Kelle, Andreas Rolf, Sabine Zitzmann, Elif Peker, Tommaso D'Angelo, Faraz Pathan, Elen, Silvia Valbuena, Rocio Hinojar, Christophe Arendt, Jagat Narula, Eva Herrmann, Andreas M Zeiher, Eike Nagel
BACKGROUND: Coronary artery disease (CAD) remains the major cause of cardiac morbidity and mortality worldwide, despite the advances in treatment with coronary revascularization and modern antiremodeling therapy. Risk stratification in CAD patients is primarily based on left ventricular volumes, ejection fraction (LVEF), risk scores, and the presence and extent of late gadolinium enhancement (LGE). The prognostic role of T1 mapping in noninfarcted myocardium in CAD patients has not yet been determined...
February 20, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29417419/summed-thickening-score-by-myocardial-perfusion-imaging-a-risk-factor-of-left-ventricular-remodeling-in-patients-with-myocardial-infarction
#3
Wei Yang, Feifei Zhang, Haipeng Tang, Xiaoliang Shao, Jianfeng Wang, Xiaosong Wang, Xiaonan Shao, Wenchong Xin, Ling Yang, Weihua Zhou, Yuetao Wang
BACKGROUND: Left ventricular (LV) remodeling has adverse effects on the prognosis of patients with myocardial infarction (MI). The aim of this study is to identify the risk factors of LV remodeling in MI patients by radionuclide myocardial imaging. METHODS AND RESULTS: This retrospective study consisted of 92 patients who had a history of definite prior MI on ECG and underwent both resting gated single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) and positron emission tomography (PET) myocardial metabolism imaging...
February 7, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29398688/late-gadolinium-enhancement-for-prediction-of-mutation-positive-hypertrophic-cardiomyopathy-on-the-basis-of-panel-wide-sequencing
#4
Ryota Teramoto, Noboru Fujino, Tetsuo Konno, Akihiro Nomura, Yoji Nagata, Toyonobu Tsuda, Hayato Tada, Kenji Sakata, Masakazu Yamagishi, Kenshi Hayashi, Masa-Aki Kawashiri
BACKGROUND: Cardiac magnetic resonance (CMR) with late gadolinium enhancement (LGE) revealed a substantial variation in the extent of myocardial scarring, a pathological hallmark of hypertrophic cardiomyopathy (HCM). However, few data exist regarding the relationship between the presence of gene mutations and the extent of LGE. Therefore, we aimed to investigate whether variations in the extent of LGE in HCM patients can be explained by the presence or absence of disease-causing mutations...
February 3, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29203081/semi-automated-qrs-score-as-a-predictor-of-survival-in-crt-treated-patients-with-strict-left-bundle-branch-block
#5
C Reitan, U Chaudhry, B Atwater, J Jacobsson, J P Couderc, X Xia, J Carlson, P G Platonov, R Borgquist
BACKGROUND: Cardiac Resynchronization Therapy (CRT) is widely used for treating selected heart failure patients, but patients with myocardial scar respond worse to treatment. The Selvester QRS scoring system estimates myocardial scar burden using 12-lead ECG. This study's objective was to investigate the scores correlation to mortality in a CRT population. METHODS AND RESULTS: Data on consecutive CRT patients was collected. 401 patients with LBBB and available ECG data were included in the study...
November 15, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/29178893/3d-whole-heart-phase-sensitive-inversion-recovery-cmr-for-simultaneous-black-blood-late-gadolinium-enhancement-and-bright-blood-coronary-cmr-angiography
#6
Giulia Ginami, Radhouene Neji, Imran Rashid, Amedeo Chiribiri, Tevfik F Ismail, René M Botnar, Claudia Prieto
BACKGROUND: Phase sensitive inversion recovery (PSIR) applied to late gadolinium enhancement (LGE) imaging is widely used in clinical practice. However, conventional 2D PSIR LGE sequences provide sub-optimal contrast between scar tissue and blood pool, rendering the detection of subendocardial infarcts and scar segmentation challenging. Furthermore, the acquisition of a low flip angle reference image doubles the acquisition time without providing any additional diagnostic information...
November 27, 2017: Journal of Cardiovascular Magnetic Resonance
https://www.readbyqxmd.com/read/29066100/the-selvester-qrs-score-as-a-predictor-of-cardiac-events-in-nonischemic-dilated-cardiomyopathy
#7
Hiroaki Hiraiwa, Takahiro Okumura, Akinori Sawamura, Yuki Sugiura, Toru Kondo, Naoki Watanabe, Soichiro Aoki, Takeo Ichii, Katsuhide Kitagawa, Naoaki Kano, Kenji Fukaya, Kenji Furusawa, Ryota Morimoto, Kyosuke Takeshita, Yasuko K Bando, Toyoaki Murohara
BACKGROUND: Myocardial fibrosis is associated with poor prognosis in nonischemic dilated cardiomyopathy (NIDCM) patients. The Selvester QRS score on 12-lead electrocardiogram is associated with both the amount of myocardial scar and poor prognosis in myocardial infarction patients. However, its use in NIDCM patients is limited. We investigated the prognostic value of the QRS score and its association with collagen volume fraction (CVF) in NIDCM patients. METHODS: We enrolled 91 consecutive NIDCM patients (66 men, 53±13 years) without permanent pacemakers or cardiac resynchronization therapy devices...
October 20, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/28928157/alteration-of-cholinergic-anti-inflammatory-pathway-in-rat-with-ischemic-cardiomyopathy-modified-electrophysiological-function-of-heart
#8
Shu-Jie Wu, Yue-Chun Li, Zhe-Wei Shi, Zhong-Hao Lin, Zhi-Heng Rao, Si-Chao Tai, Mao-Ping Chu, Lei Li, Jia-Feng Lin
BACKGROUND: With chronic ischemia after myocardial infarction, the resulting scar tissue result in electrical and structural remodeling vulnerable to an arrhythmogenic substrate. The cholinergic anti-inflammatory pathway elicited by vagal nerve via α7 nicotinic acetylcholine receptors (α7-nAChR) can modulate local and systemic inflammatory responses. Here, we aimed to clarify a novel mechanism for the antiarrhythmogenic properties of vagal nerve during the ischemic cardiomyopathy (ICM)...
September 19, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28680841/hepatic-encephalopathy-in-liver-cirrhosis
#9
Herbert Djiambou-Nganjeu
Liver cirrhosis is a worldwide gastroenterological condition, characterized by a slow, progressive and irreversible replacement of liver cells by fibrous tissue (scar) that prevents liver function. This condition often leads to the development of other syndromes. Cardiac complications can be indicated through abnormal QTc interval and arrhythmias, thereby their analysis aids in the prevention of cardiovascular events. Most cirrhotic cases have abnormal laboratory values (bilirubin, albumin, AST, ALT, AST/ALT, INR) indicating the presence of concomitant infection, inflammation and coagulopathy...
March 2017: Journal of Translational Internal Medicine
https://www.readbyqxmd.com/read/28412420/stress-perfusion-cmr-in-patients-with-known-and-suspected-cad-prognostic-value-and-optimal-ischemic-threshold-for-revascularization
#10
Gabriella Vincenti, Pier Giorgio Masci, Pierre Monney, Tobias Rutz, Sarah Hugelshofer, Mirdita Gaxherri, Olivier Muller, Juan F Iglesias, Eric Eeckhout, Valentina Lorenzoni, Cyril Pellaton, Christophe Sierro, Juerg Schwitter
OBJECTIVES: This study sought to determine the ischemia threshold and additional prognostic factors that identify patients for safe deferral from revascularizations in a large cohort of all-comer patients with known or suspected coronary artery disease (CAD). BACKGROUND: Stress-perfusion cardiac magnetic resonance (CMR) is increasingly used in daily practice for ischemia detection. However, there is insufficient evidence about the ischemia burden that identifies patients who benefit from revascularization versus those with a good prognosis who receive drugs only...
May 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28382083/prognostic-implication-of-the-qrs-axis-and-its-association-with-myocardial-scarring-in-patients-with-left-bundle-branch-block
#11
Chan Soon Park, Myung-Jin Cha, Eue-Keun Choi, Seil Oh
BACKGROUND AND OBJECTIVES: Left bundle branch block (LBBB) with left axis deviation (LAD) has a worse prognosis than LBBB with a normal axis, and myocardial dysfunction has been suggested as a cause of left axis deviation. This study investigated the prognostic significance of the QRS axis in patients with LBBB and analyzed its relationship with the amount of myocardial scarring. SUBJECTS AND METHODS: A total of 829 patients were diagnosed with LBBB at Seoul National University Hospital from October 2004 to June 2014...
March 2017: Korean Circulation Journal
https://www.readbyqxmd.com/read/28274572/comparison-of-electrocardiography-markers-and-speckle-tracking-echocardiography-for-assessment-of-left-ventricular-myocardial-scar-burden-in-patients-with-previous-myocardial-infarction
#12
COMPARATIVE STUDY
Eirik Nestaas, Jhih-Yuan Shih, Marit K Smedsrud, Ola Gjesdal, Einar Hopp, Kristina H Haugaa, Thor Edvardsen
Myocardial scar burden is an important prognostic factor after myocardial infarction. This cohort study compared assessment of left ventricle scar burden between pathological Q waves on electrocardiography (ECG), Selvester multiparametric ECG scoring system for scar burden, and global longitudinal strain (GLS) by speckle-tracking echocardiography 6 months after myocardial infarction. The scar burden was defined by late gadolinium enhancement cardiac magnetic resonance as fraction of total left ventricle tissue...
May 1, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28272813/scared-for-the-scar-fearsome-impact-of-acute-cardiovascular-disease-on-perceived-kinesiophobia-fear-of-movement
#13
Natale D Brunetti, Antonio Guerra, Riccardo Ieva, Michele Correale, Francesco Santoro, Nicola Tarantino, Matteo Di Biase
BACKGROUND: To assess levels of kinesiophobia (fear of movement) in patients hospitalized for acute cardiovascular disease. HYPOTHESIS: Increased levels of kinesiophobia can be found in subjects hospitalized for acute cardiovascular disease. METHODS: Seventy-four consecutive patients admitted for acute coronary syndrome and 58 for acute heart failure were enrolled in the study and assessed by the Tampa Scale for the evaluation of kinesiophobia...
March 8, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28248005/evaluation-of-the-ecg-based-selvester-scoring-method-to-estimate-myocardial-scar-burden-and-predict-clinical-outcome-in-patients-with-left-bundle-branch-block-with-comparison-to-late-gadolinium-enhancement-cmr-imaging
#14
Uzma Chaudhry, Pyotr G Platonov, Robert Jablonowski, Jean-Philippe Couderc, Henrik Engblom, Xiajuang Xia, Björn Wieslander, Brett D Atwater, David G Strauss, Jesper Van der Pals, Martin Ugander, Marcus Carlsson, Rasmus Borgquist
BACKGROUND: Myocardial scar burden quantification is an emerging clinical parameter for risk stratification of sudden cardiac death and prediction of ventricular arrhythmias in patients with left ventricular dysfunction. We investigated the relationships among semiautomated Selvester score burden and late gadolinium enhancement-cardiovascular magnetic resonance (LGE-CMR) assessed scar burden and clinical outcome in patients with underlying heart failure, left bundle branch block (LBBB) and implantable cardioverter-defibrillator (ICD) treatment...
March 1, 2017: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/28143731/patient-body-image-self-esteem-and-cosmetic-results-of-minimally-invasive-robotic-cardiac-surgery
#15
RANDOMIZED CONTROLLED TRIAL
Taner İyigün, Mehmet Kaya, Sevil Özgül Gülbeyaz, Nurhan Fıstıkçı, Gözde Uyanık, Bilge Yılmaz, Burak Onan, Korhan Erkanlı
BACKGROUND: Patient-reported outcome measures reveal the quality of surgical care from the patient's perspective. We aimed to compare body image, self-esteem, hospital anxiety and depression, and cosmetic outcomes by using validated tools between patients undergoing robot-assisted surgery and those undergoing conventional open surgery. MATERIALS AND METHODS: This single-center, multidisciplinary, randomized, prospective study of 62 patients who underwent cardiac surgery was conducted at Hospital from May 2013 to January 2015...
March 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/27801994/clinical-evaluation-of-three-dimensional-late-enhancement-mri
#16
Konstantinos Bratis, Markus Henningsson, Chrisanthos Grigoratos, Matteo Dell' Omodarme, Konstantinos Chasapides, Rene Botnar, Eike Nagel
PURPOSE: To assess the diagnostic value of three-dimensional late enhancement (3D-LGE) for the detection of myocardial necrosis in a routine clinical setting. 3D-LGE has been proposed as a novel magnetic resonance (MR) technique for the accurate detection of myocardial scar in both the ventricles and atria. Its performance in clinical practice has been poorly examined. MATERIALS AND METHODS: Fifty-seven patients referred for cardiac MR examination including scar imaging were prospectively enrolled...
November 1, 2016: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/27659890/adverse-diastolic-remodeling-after-reperfused-st-elevation-myocardial-infarction-an-important-prognostic-indicator
#17
Tuan L Nguyen, Justin Phan, Jarred Hogan, Leia Hee, Daniel Moses, James Otton, Upul Premawardhana, Rohan Rajaratnam, Craig P Juergens, Hany Dimitri, John K French, David Richards, Liza Thomas
OBJECTIVES: We sought to determine the relationship of adverse diastolic remodeling (ie, worsening diastolic or persistent restrictive filling) with infarct scar characteristics, and to evaluate its prognostic value after ST-segment elevation myocardial infarction (STEMI). BACKGROUND: Severe diastolic dysfunction (restrictive filling) has known prognostic value post STEMI. However, ongoing left ventricular (LV) remodeling post STEMI may alter diastolic function even if less severe...
October 2016: American Heart Journal
https://www.readbyqxmd.com/read/27553101/prognostic-implications-of-left-ventricular-scar-determined-by-late-gadolinium-enhanced-cardiac-magnetic-resonance-in-patients-with-atrial-fibrillation
#18
Promporn Suksaranjit, Christopher J McGann, Nazem Akoum, Joseph Biskupiak, Gregory J Stoddard, Eugene G Kholmovski, Leenhapong Navaravong, Allen Rassa, Erik Bieging, Lowell Chang, Imran Haider, Nassir F Marrouche, Brent D Wilson
Left ventricular (LV) scar identified by late gadolinium enhanced (LGE) cardiac magnetic resonance (CMR) is associated with adverse outcomes in coronary artery disease and cardiomyopathies. We sought to determine the prognostic significance of LV-LGE in atrial fibrillation (AF). We studied 778 consecutive patients referred for radiofrequency ablation of AF who underwent CMR. Patients with coronary artery disease, previous myocardial infarction, or hypertrophic or dilated cardiomyopathy were excluded. The end points of interest were major adverse cardiac and cerebrovascular events (MACCE), defined as a composite of cardiovascular death, myocardial infarction, and ischemic stroke/transient ischemic attack...
October 1, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27397447/anesthetic-implications-of-subxiphoid-coronary-artery-bypass-surgery
#19
Murali Chakravarthy, Muralimanohar Veerappa, Vivek Jawali, Nischal Pandya, Jayaprakash Krishnamoorthy, Geetha Muniraju, Antony George, Jitumoni Baishya
BACKGROUND: Minimal invasive surgeries are carried out to benefit the patient with less pain, blood loss, mechanical ventilation and hospital stay; a smaller scar is not the aim. Minimal invasive cardiac surgeries are carried out via small sternotomy, small thoracotomy and via robotic arms. Subxiphoid route is a novel method and avoids sternotomy. AIM: This case series is an attempt to understand the anesthetic modifications required. Secondly, whether it is feasible to carry out subxiphoid coronary artery bypass surgery...
July 2016: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/27390960/electrocardiographic-measurement-of-infarct-size-compared-to-cardiac-mri-in-reperfused-first-time-st-segment-elevation-myocardial-infarction
#20
COMPARATIVE STUDY
Lewis E Holmes, Tuan L Nguyen, Leia Hee, James Otton, Daniel A Moses, John K French, Liza Thomas, David A B Richards, Craig P Juergens
BACKGROUND: Myocardial infarct size (IS) following ST-segment elevation myocardial infarction (STEMI) is an important prognostic factor. We assessed the Selvester 32-point QRS score from the 12-lead ECG for measurement of IS in STEMI patients receiving reperfusion therapy compared to cardiac magnetic resonance imaging (CMRI). Furthermore we sought to explore the impact of microvascular obstruction (MVO) on the scoring system, and determine factors contributing to discrepancies between CMRI IS and Selvester score...
October 1, 2016: International Journal of Cardiology
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