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Cardiac scar score

Gabriella Vincenti, Pier Giorgio Masci, Pierre Monney, Tobias Rutz, Sarah Hugelshofer, Mirdita Gaxherri, Olivier Muller, Juan F Iglesias, Eric Eeckhout, Valentina Lorenzoni, Cyril Pellaton, Christophe Sierro, Juerg Schwitter
OBJECTIVES: This study sought to determine the ischemia threshold and additional prognostic factors that identify patients for safe deferral from revascularizations in a large cohort of all-comer patients with known or suspected coronary artery disease (CAD). BACKGROUND: Stress-perfusion cardiac magnetic resonance (CMR) is increasingly used in daily practice for ischemia detection. However, there is insufficient evidence about the ischemia burden that identifies patients who benefit from revascularization versus those with a good prognosis who receive drugs only...
April 10, 2017: JACC. Cardiovascular Imaging
Chan Soon Park, Myung-Jin Cha, Eue-Keun Choi, Seil Oh
BACKGROUND AND OBJECTIVES: Left bundle branch block (LBBB) with left axis deviation (LAD) has a worse prognosis than LBBB with a normal axis, and myocardial dysfunction has been suggested as a cause of left axis deviation. This study investigated the prognostic significance of the QRS axis in patients with LBBB and analyzed its relationship with the amount of myocardial scarring. SUBJECTS AND METHODS: A total of 829 patients were diagnosed with LBBB at Seoul National University Hospital from October 2004 to June 2014...
March 2017: Korean Circulation Journal
Eirik Nestaas, Jhih-Yuan Shih, Marit K Smedsrud, Ola Gjesdal, Einar Hopp, Kristina H Haugaa, Thor Edvardsen
Myocardial scar burden is an important prognostic factor after myocardial infarction. This cohort study compared assessment of left ventricle scar burden between pathological Q waves on electrocardiography (ECG), Selvester multiparametric ECG scoring system for scar burden, and global longitudinal strain (GLS) by speckle-tracking echocardiography 6 months after myocardial infarction. The scar burden was defined by late gadolinium enhancement cardiac magnetic resonance as fraction of total left ventricle tissue...
May 1, 2017: American Journal of Cardiology
Natale D Brunetti, Antonio Guerra, Riccardo Ieva, Michele Correale, Francesco Santoro, Nicola Tarantino, Matteo Di Biase
BACKGROUND: To assess levels of kinesiophobia (fear of movement) in patients hospitalized for acute cardiovascular disease. HYPOTHESIS: Increased levels of kinesiophobia can be found in subjects hospitalized for acute cardiovascular disease. METHODS: Seventy-four consecutive patients admitted for acute coronary syndrome and 58 for acute heart failure were enrolled in the study and assessed by the Tampa Scale for the evaluation of kinesiophobia...
March 8, 2017: Clinical Cardiology
Uzma Chaudhry, Pyotr G Platonov, Robert Jablonowski, Jean-Philippe Couderc, Henrik Engblom, Xiajuang Xia, Björn Wieslander, Brett D Atwater, David G Strauss, Jesper Van der Pals, Martin Ugander, Marcus Carlsson, Rasmus Borgquist
BACKGROUND: Myocardial scar burden quantification is an emerging clinical parameter for risk stratification of sudden cardiac death and prediction of ventricular arrhythmias in patients with left ventricular dysfunction. We investigated the relationships among semiautomated Selvester score burden and late gadolinium enhancement-cardiovascular magnetic resonance (LGE-CMR) assessed scar burden and clinical outcome in patients with underlying heart failure, left bundle branch block (LBBB) and implantable cardioverter-defibrillator (ICD) treatment...
March 1, 2017: Annals of Noninvasive Electrocardiology
Taner İyigün, Mehmet Kaya, Sevil Özgül Gülbeyaz, Nurhan Fıstıkçı, Gözde Uyanık, Bilge Yılmaz, Burak Onan, Korhan Erkanlı
BACKGROUND: Patient-reported outcome measures reveal the quality of surgical care from the patient's perspective. We aimed to compare body image, self-esteem, hospital anxiety and depression, and cosmetic outcomes by using validated tools between patients undergoing robot-assisted surgery and those undergoing conventional open surgery. MATERIALS AND METHODS: This single-center, multidisciplinary, randomized, prospective study of 62 patients who underwent cardiac surgery was conducted at Hospital from May 2013 to January 2015...
March 2017: International Journal of Surgery
Konstantinos Bratis, Markus Henningsson, Chrisanthos Grigoratos, Matteo Dell' Omodarme, Konstantinos Chasapides, Rene Botnar, Eike Nagel
PURPOSE: To assess the diagnostic value of three-dimensional late enhancement (3D-LGE) for the detection of myocardial necrosis in a routine clinical setting. 3D-LGE has been proposed as a novel magnetic resonance (MR) technique for the accurate detection of myocardial scar in both the ventricles and atria. Its performance in clinical practice has been poorly examined. MATERIALS AND METHODS: Fifty-seven patients referred for cardiac MR examination including scar imaging were prospectively enrolled...
November 1, 2016: Journal of Magnetic Resonance Imaging: JMRI
Tuan L Nguyen, Justin Phan, Jarred Hogan, Leia Hee, Daniel Moses, James Otton, Upul Premawardhana, Rohan Rajaratnam, Craig P Juergens, Hany Dimitri, John K French, David Richards, Liza Thomas
OBJECTIVES: We sought to determine the relationship of adverse diastolic remodeling (ie, worsening diastolic or persistent restrictive filling) with infarct scar characteristics, and to evaluate its prognostic value after ST-segment elevation myocardial infarction (STEMI). BACKGROUND: Severe diastolic dysfunction (restrictive filling) has known prognostic value post STEMI. However, ongoing left ventricular (LV) remodeling post STEMI may alter diastolic function even if less severe...
October 2016: American Heart Journal
Promporn Suksaranjit, Christopher J McGann, Nazem Akoum, Joseph Biskupiak, Gregory J Stoddard, Eugene G Kholmovski, Leenhapong Navaravong, Allen Rassa, Erik Bieging, Lowell Chang, Imran Haider, Nassir F Marrouche, Brent D Wilson
Left ventricular (LV) scar identified by late gadolinium enhanced (LGE) cardiac magnetic resonance (CMR) is associated with adverse outcomes in coronary artery disease and cardiomyopathies. We sought to determine the prognostic significance of LV-LGE in atrial fibrillation (AF). We studied 778 consecutive patients referred for radiofrequency ablation of AF who underwent CMR. Patients with coronary artery disease, previous myocardial infarction, or hypertrophic or dilated cardiomyopathy were excluded. The end points of interest were major adverse cardiac and cerebrovascular events (MACCE), defined as a composite of cardiovascular death, myocardial infarction, and ischemic stroke/transient ischemic attack...
October 1, 2016: American Journal of Cardiology
Murali Chakravarthy, Muralimanohar Veerappa, Vivek Jawali, Nischal Pandya, Jayaprakash Krishnamoorthy, Geetha Muniraju, Antony George, Jitumoni Baishya
BACKGROUND: Minimal invasive surgeries are carried out to benefit the patient with less pain, blood loss, mechanical ventilation and hospital stay; a smaller scar is not the aim. Minimal invasive cardiac surgeries are carried out via small sternotomy, small thoracotomy and via robotic arms. Subxiphoid route is a novel method and avoids sternotomy. AIM: This case series is an attempt to understand the anesthetic modifications required. Secondly, whether it is feasible to carry out subxiphoid coronary artery bypass surgery...
July 2016: Annals of Cardiac Anaesthesia
Lewis E Holmes, Tuan L Nguyen, Leia Hee, James Otton, Daniel A Moses, John K French, Liza Thomas, David A B Richards, Craig P Juergens
BACKGROUND: Myocardial infarct size (IS) following ST-segment elevation myocardial infarction (STEMI) is an important prognostic factor. We assessed the Selvester 32-point QRS score from the 12-lead ECG for measurement of IS in STEMI patients receiving reperfusion therapy compared to cardiac magnetic resonance imaging (CMRI). Furthermore we sought to explore the impact of microvascular obstruction (MVO) on the scoring system, and determine factors contributing to discrepancies between CMRI IS and Selvester score...
October 1, 2016: International Journal of Cardiology
Yuki Tanaka, Takashi Miyamoto, Yuji Naito, Shuichi Yoshitake, Akihiro Sasahara, Kagami Miyaji
BACKGROUND: We report a new, noninvasive Zip surgical skin closure device (ZipLine Medical, Campbell, CA). This device is considered to have good cosmetic outcomes after operations and reduces surgical time. In this study, skin closure using the Zip device was compared with subcuticular sutures and the usefulness and safety of this new device was evaluated. METHODS: This was a prospective, randomized study of 214 patients who underwent cardiac operations through a median sternotomy from June 2014 to December 2015...
October 2016: Annals of Thoracic Surgery
Tobias Reichlin, Roger Abächerli, Raphael Twerenbold, Michael Kühne, Beat Schaer, Christian Müller, Christian Sticherling, Stefan Osswald
The 12-lead electrocardiogram (ECG) is the most frequently used technology in clinical cardiology. It is critical for evidence-based management of patients with most cardiovascular conditions, including patients with acute myocardial infarction, suspected chronic cardiac ischaemia, cardiac arrhythmias, heart failure and implantable cardiac devices. In contrast to many other techniques in cardiology, the ECG is simple, small, mobile, universally available and cheap, and therefore particularly attractive. Standard ECG interpretation mainly relies on direct visual assessment...
2016: Swiss Medical Weekly
Rajiv G Menon, G Wilson Miller, Jean Jeudy, Sanjay Rajagopalan, Taehoon Shin
PURPOSE: To develop a three-dimensional, free-breathing, late gadolinium enhancement (3D FB-LGE) cardiovascular magnetic resonance (CMR) technique, and to compare it with clinically used two-dimensional breath-hold LGE (2D BH-LGE). METHODS: The proposed 3D FB-LGE method consisted of inversion preparation, inversion delay, fat saturation, outer volume suppression, one-dimensional projection navigators, and a segmented stack of spirals acquisition. The 3D FB-LGE and 2D BH-LGE scans were performed on 29 cardiac patients...
April 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
Sandra Hamada, Joerg Schroeder, Rainer Hoffmann, Ertunc Altiok, Andras Keszei, Mohammad Almalla, Andreas Napp, Nikolaus Marx, Michael Becker
BACKGROUND: Cardiac magnetic resonance imaging (CMR) has been established as a powerful tool for predicting mortality. However, its application is limited by availability and various contraindications. The aim of this study was to evaluate the predictive value of layer-specific myocardial deformation analysis as assessed by strain echocardiography for cardiac events in patients with chronic ischemic left ventricular dysfunction in comparison with CMR. METHODS: Three hundred ninety patients (mean age, 63 ± 4 years; 69% men; mean left ventricular ejection fraction [LVEF], 41 ± 7%) with chronic ischemic cardiomyopathy were prospectively enrolled and underwent strain echocardiography and CMR within 3 ± 1 days...
May 2016: Journal of the American Society of Echocardiography
Mohammed J Sheriff, Omar Mouline, Chijen Hsu, Stuart M Grieve, Michael K Wilson, Paul G Bannon, Michael P Vallely, Rajesh Puranik
BACKGROUND: The euroSCORE II is a widely used pre-coronary artery bypass graft surgery (CAGS) risk score, but its predictive power lacks the specificity to predict outcomes in high-risk patients (<LVEF 40%) due to changes in cardiac surgery case mix, revascularisation techniques and related outcomes in recent years. We investigated the utility of Cardiac Magnetic Resonance Imaging (CMRI) in predicting immediate and six-week outcomes after CAGS. METHODS: Fifty-two consecutive patients with high euroSCORE II (>16) and left ventricular (LV) dysfunction (<40%) based on 2D-echocardiography who underwent CAGS and in whom CMRI (1...
June 2016: Heart, Lung & Circulation
Nathan Mewton, David G Strauss, Patricia Rizzi, Richard L Verrier, Chia Ying Liu, Larisa G Tereshchenko, Bruce Nearing, Gustavo J Volpe, Francis E Marchlinski, John Moxley, Tony Killian, Katherine C Wu, Peter Spooner, João A C Lima
BACKGROUND: Increased QRS score and wide spatial QRS-T angle are independent predictors of cardiovascular mortality in the general population. Our main objective was to assess whether a QRS score ≥ 5 and/or QRS-T angle ≥ 105° enable screening of patients for myocardial scar features. METHODS: Seventy-seven patients of age ≤ 70 years with QRS score ≥ 5 and/or spatial QRS-T angle ≥ 105° as well as left ventricular ejection fraction (LVEF) >35% were enrolled in the study...
January 2016: Annals of Noninvasive Electrocardiology
Evrim B Turkbey, Marcelo S Nacif, Mengye Guo, Robyn L McClelland, Patricia B R P Teixeira, Diane E Bild, R Graham Barr, Steven Shea, Wendy Post, Gregory Burke, Matthew J Budoff, Aaron R Folsom, Chia-Ying Liu, João A Lima, David A Bluemke
IMPORTANCE: Myocardial scarring leads to cardiac dysfunction and poor prognosis. The prevalence of and factors associated with unrecognized myocardial infarction and scar have not been previously defined using contemporary methods in a multiethnic US population. OBJECTIVE: To determine prevalence of and factors associated with myocardial scar in middle- and older-aged individuals in the United States. DESIGN, SETTING, AND PARTICIPANTS: The Multi-Ethnic Study of Atherosclerosis (MESA) study is a population-based cohort in the United States...
November 10, 2015: JAMA: the Journal of the American Medical Association
Suzanne L Duce, Jonathan R Weir-McCall, Stephen J Gandy, Shona Z Matthew, Deirdre B Cassidy, Lynne McCormick, Petra Rauchhaus, Helen Looker, Helen M Colhoun, J Graeme Houston
BACKGROUND: Whole body cardiovascular MR (WB CVMR) combines whole body angiography and cardiac MR assessment. It is accepted that there is a high disease burden in patients with diabetes, however the quantification of the whole body atheroma burden in both arterial and cardiac disease has not been previously reported. In this study we compare the quantified atheroma burden in those individuals with and without diabetes by clinical cardiovascular disease (CVD) status. METHODS: 158 participants underwent WB CVMR, and were categorised into one of four groups: (1) type 2 diabetes mellitus (T2DM) with CVD; (2) T2DM without CVD; (3) CVD without T2DM; (4) healthy controls...
September 18, 2015: Cardiovascular Diabetology
Yoshihiro Sobue, Masahide Harada, Masayuki Koshikawa, Tomohide Ichikawa, Mayumi Yamamoto, Kentaro Okuda, Yasuchika Kato, Masayoshi Sarai, Eiichi Watanabe, Yukio Ozaki
BACKGROUND: Cardiac sarcoidosis (CS) generates myocardial scar and arrhythmogenic substrate. CS diagnosis according to the Japanese Ministry of Health and Welfare guidelines relies, among others, on cardiac magnetic resonance imaging with late gadolinium enhancement (CMR-LGE). However, access to CMR-LGE is limited. The electrocardiography-based Selvester QRS score has been validated for identifying myocardial scar in ischemic/nonischemic cardiomyopathy, but its efficacy has not been tested to evaluate CS...
December 2015: Heart Rhythm: the Official Journal of the Heart Rhythm Society
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