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Program development and evaluation

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https://www.readbyqxmd.com/read/29223767/evaluation-of-a-national-pediatric-subinternship-curriculum-implemented-through-individual-learning-plans
#1
Linda R Tewksbury, Cristina Carter, Lyuba Konopasek, Sandra M Sanguino, Janice L Hanson
OBJECTIVE: The Council on Medical Student Education in Pediatrics and Association of Pediatric Program Directors developed a Pediatric Subinternship (CAPS) Curriculum for use with an individualized learning plan (ILP). The authors determined which learning objectives (LOs) pediatric subinterns selected when provided the CAPS Curriculum, summarized students' self-reported progress, and determined feasibility of ILPs in subinternship. METHODS: Students from 10 medical schools completed a standardized ILP during pediatric subinternship...
December 6, 2017: Academic Pediatrics
https://www.readbyqxmd.com/read/29223704/decellularized-heart-ecm-hydrogel-using-supercritical-carbon-dioxide-for-improved-angiogenesis
#2
Yoojin Seo, Youngmee Jung, Soo Hyun Kim
Initial angiogenesis within the first 3 days is critical for healing ischemic diseases such as myocardial infarction. Recently, decellularized extracellular matrix (dECM) has been reported to provide tissue-derived ECM components and can be used as a scaffold for cell delivery for angiogenesis in tissue engineering. Decellularization by various detergents such as sodium dodecyl sulfate (SDS) and triton X-100 can remove the cell nuclei in tissue organs. However, this leads to ECM structure denaturation, decreased presence of various ECM proteins and cytokines, and loss of mechanical properties...
December 6, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/29223624/implementation-of-the-alarm-distress-baby-scale-as-a-universal-screening-instrument-in-primary-care-feasibility-acceptability-and-predictors-of-professionals-adherence-to-guidelines
#3
Johanne Smith-Nielsen, Nicole Lønfeldt, Antoine Guedeney, Mette Skovgaard Væver
BACKGROUND: Infant socioemotional development is often held under informal surveillance, but a formal screening program is needed to ensure systematic identification of developmental risk. Even when screening programs exist, they are often ineffective because health care professionals do not adhere to screening guidelines, resulting in low screening prevalence rates. OBJECTIVES: To examine feasibility and acceptability of implementing universal screening for infant socioemotional problems with the Alarm Distress Baby Scale in primary care...
November 21, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29223325/cochrane-qualitative-and-implementation-methods-group-guidance-paper-3-methods-for-assessing-evidence-on-intervention-implementation
#4
Margaret Cargo, Janet Harris, Tomas Pantoja, Andrew Booth, Angela Harden, Karin Hannes, James Thomas, Kate Flemming, Ruth Garside, Jane Noyes
OBJECTIVE: This article provides reviewers with guidance on methods for identifying and processing evidence to understand intervention implementation. STUDY DESIGN AND SETTING: Strategies, tools and methods are applied to the systematic review process to illustrate how process and implementation can be addressed using quantitative, qualitative and other sources of evidence (i.e., descriptive textual, non-empirical). RESULTS: Reviewers can take steps to navigate the heterogeneity and level of uncertainty present in the concepts, measures and methods used to assess implementation...
December 6, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/29223142/designing-tyrosinase-sirnas-by-multiple-prediction-algorithms-and-evaluation-of-their-anti-melanogenic-effects
#5
Ok-Seon Kwon, Soo-Jung Kwon, Jin Sang Kim, Gunbong Lee, Han-Joo Maeng, Jeongmi Lee, Gwi Seo Hwang, Hyuk-Jin Cha, Kwang-Hoon Chun
Melanin is a pigment produced from tyrosine in melanocytes. Although melanin has a protective role against UVB radiation-induced damage, it is also associated with the development of melanoma and darker skin tone. Tyrosinase is a key enzyme in melanin synthesis, which regulates the rate-limiting step during conversion of tyrosine into DOPA and dopaquinone. To develop effective RNA interference therapeutics, we designed a melanin siRNA pool by applying multiple prediction programs to reduce human tyrosinase levels...
December 8, 2017: Biomolecules & Therapeutics
https://www.readbyqxmd.com/read/29221944/living-uterus-donation-and-transplantation-experience-of-interest-and-screening-in-a-single-center-in-the-united-states
#6
Liza Johannesson, Kristin Wallis, E Colin Koon, Gregory J Mckenna, Tiffany Anthony, Sara G Leffingwell, Goran B Klintmalm, Robert T Gunby, Giuliano Testa
BACKGROUND: Little is known about attitudes toward uterus donation and transplantation in society and the interest of the women the treatment is aimed to assist. OBJECTIVE: This study examined the interest of recipients and living donors in our uterus transplantation program; it describes the screening protocol we developed and the results of the screening and reports demographic data and characteristics of screened candidates. STUDY DESIGN: Initial screening and evaluation included physical examinations by a gynecologist and a transplant surgeon; psychological evaluation; imaging (x-ray, computed tomography, ultrasound); blood tests; immunological testing; viral, bacterial, and fungal testing; drug screen; hormonal testing; Pap smear; urinalysis; and electrocardiogram...
December 5, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29221802/inflammation-in-the-prediction-of-type-2-diabetes-and-hypertension-in-healthy-adults
#7
Ki-Chul Sung, Seungho Ryu, Joo-Wook Sung, Yong Bum Kim, Yu Sam Won, Dong Sik Cho, Sun H Kim, Alice Liu
BACKGROUND: While inflammation is associated with obesity and insulin resistance, their inter-relationships in the development of type 2 diabetes or hypertension are not clear. AIM OF THE STUDY: To evaluate inflammatory markers in prediction of type 2 diabetes and hypertension. METHODS: The study population of this retrospective cohort study consisted of individuals who participated in a comprehensive health screening program with measurement of white blood cell count and C-reactive protein from 2002-2010 (N = 96,606) in nondiabetic and normotensive Koreans...
December 5, 2017: Archives of Medical Research
https://www.readbyqxmd.com/read/29221765/advances-in-fetal-echocardiography
#8
REVIEW
Helena M Gardiner
The development of fetal echocardiography and success in prenatal cardiac screening programs over the past 30 years has been driven by technical innovation and influenced by the different approaches of the various specialties practicing it. Screening for congenital heart defects no longer focuses on examining a limited number of pregnant women thought to be at increased risk, but instead forms an integrated part of a high-quality anatomical ultrasound performed in the second trimester using the 'five-transverse view' protocol...
December 5, 2017: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29221541/the-global-health-nursing-imperative-using-competency-based-analysis-to-strengthen-accountability-for-population-focused-practice-education-and-research
#9
Barbara Joyce, Nancy Brown-Schott, Vicki Hicks, Regina Gina Johnson, Monica Harmon, Lucille Pilling
BACKGROUND: The Quad Council Competencies for Public Health Nurses are used to guide community and public health nursing course development in baccalaureate nursing programs. As clinical practice has expanded to global settings, the appropriateness of the 2011 Quad Council Public Health Nursing (PHN) Competencies to guide global clinical practice and evaluation was questioned. OBJECTIVE: To describe a comparison and analysis of three sets of competencies: PHN competencies, competencies for global health nurses, and interprofessional competencies for health professionals...
May 2017: Annals of Global Health
https://www.readbyqxmd.com/read/29221515/socioeconomic-disparities-in-the-prevalence-of-cardiometabolic-risk-factors-in-ghanaian-women
#10
Jeffrey Boakye, Danielle Mensah, Swati Sakhuja, Pauline E Jolly, Tomi Akinyemiju
BACKGROUND: Recent trends toward urbanization in developing countries like Ghana, coupled with nutritional transition and aging populations, have led to a rapid increase in the prevalence of noncommunicable diseases such as obesity, diabetes, and hypertension. The purpose of this study was to evaluate the association between socioeconomic status and cardiometabolic risk factors among women in Ghana. METHODS: Data for this analysis were obtained from Wave 1 of the Ghana Study of Global Aging and Health, conducted in 2007, and included women 18 years and older...
May 2017: Annals of Global Health
https://www.readbyqxmd.com/read/29220543/skin-cancer-prevention-campaign-in-childhood-survey-based-on-3-676-children-in-brazil
#11
Paulo Ricardo Criado, Jorge Ocampo-Garza, Anne Lise Dias, Walter Belda Junior, Nilton Di Chiachio, Aparecida Machado de Moraes, Meire Brasil Parada, Fátima de Oliveira Rabay, Octavio Moraes Junior, Renato Sau Rios, Cristiana Silveira da Silva, Francisco C S Ferreira, Samuel Henrique Mandeulbaum, Cidia Vasconcellos
BACKGROUND AND OBJECTIVES: Primary skin cancer prevention campaigns are essential and more effective among children, not only because of the importance of sun exposure effects during this period, but also because at this age is when individuals are developing behaviors. The Brazilian Society of Dermatology - Regional State of Sao Paulo developed and conducted, the program named "The Sun, Friend of Childhood", a school health education and disease prevention project for children and parents...
December 8, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29220291/emerging-targeted-and-immune-based-therapies-in-sarcoma
#12
Seth M Pollack, Matthew Ingham, Matthew B Spraker, Gary K Schwartz
Soft tissue and bone sarcomas are malignancies of mesenchymal origin, and more than 50 subtypes are defined. For most sarcomas, locally advanced or unresectable disease is still treated with cytotoxic chemotherapy. Recently, our understanding of subtype-specific cancer biology has expanded, and it has revealed distinct molecular alterations responsible for tumor initiation and progression. These findings have motivated the development of targeted therapies that are being evaluated in subtype-specific or biomarker-driven clinical trials...
December 8, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29219906/targeted-interventions-to-advance-a-culture-of-inquiry-at-a-large-multicampus-hospital-among-nurses
#13
Eileen J Carter, Reynaldo R Rivera, Kelly A Gallagher, Kenrick D Cato
OBJECTIVES: The aim of this study is to assist nurse leaders in developing innovative structures to foster a culture of inquiry among professional nurses. BACKGROUND: Critical to nurse's engagement in evidence-based practice (EBP) is a culture of inquiry, in which nurses critically evaluate patient care activities and actively review existing evidence to address identified clinical issues. A bundle of structural interventions was implemented across a large, multisite hospital to advance a culture of inquiry...
January 2018: Journal of Nursing Administration
https://www.readbyqxmd.com/read/29219905/systems-addressing-frail-elder-care-description-of-a-successful-model
#14
Lianna Zaven Ansryan, Harriet Udin Aronow, Jeff Edward Borenstein, Viola Mena, Flora Haus, Katherine Palmer, Ellen Chan, Jane W Swanson, Sharon Mass, Bradley Rosen, Glenn David Braunstein, Linda Burnes Bolton
OBJECTIVE: The aim of this article is to describe the Systems Addressing Frail Elder (SAFE) Care model, features of the interprofessional team and reengineered workflow, and details of the intervention. BACKGROUND: Older inpatients are vulnerable to adverse events related to frailty. SAFE Care, an interprofessional team-based program, was developed and evaluated in a cluster randomized controlled trial (C-RCT). Results found reduced length of stay and complications...
January 2018: Journal of Nursing Administration
https://www.readbyqxmd.com/read/29219894/crisis-management-simulation-establishing-a-dual-neurosurgery-and-anesthesia-training-experience
#15
Jeremy Ciporen, Haley Gillham, Michele Noles, Dawn Dillman, Mark Baskerville, Caleb Haley, Donn Spight, Ryan C Turner, Brandon P Lucke-Wold
BACKGROUND: Simulation training has been shown to be an effective teaching tool. Learner management of an intraoperative crisis such as a major cerebrovascular bleed requires effective teamwork, communication, and implementation of key skill sets at appropriate time points. This study establishes a first of a kind simulation experience in a neurosurgery/anesthesia resident (learners) team working together to manage an intraoperative crisis. METHODS: Using a cadaveric cavernous carotid injury perfusion model, 7 neurosurgery and 6 anesthesia learners, were trained on appropriate vascular injury management using an endonasal endoscopic technique...
January 2018: Journal of Neurosurgical Anesthesiology
https://www.readbyqxmd.com/read/29219305/brucellosis-improved-diagnostics-and-vaccine-insights-from-synthetic-glycans
#16
David R Bundle, John McGiven
Brucellosis is a serious zoonotic bacterial disease that is ranked by the World Health Organization among the top seven "neglected zoonoses" that threaten human health and cause poverty. It is a costly, highly contagious disease that affects ruminants, cattle, sheep, goats, and other productive animals such as pigs. Symptoms include abortions, infertility, decreased milk production, weight loss, and lameness. Brucellosis is also the most common bacterial disease that is transmitted from animals to humans, with approximately 500 000 new human cases each year...
December 8, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/29219167/quantitative-understanding-of-qtc-prolongation-and-gender-as-risk-factors-for-torsade-de-pointes
#17
Lars Johannesen, Christine Garnett, Man Luo, Shari Targum, Jens Stampe Sørensen, Nitin Mehrotra
Several risk factors for development of a potentially fatal ventricular arrhythmia, torsade de pointes, have been observed, including female gender. However, in most investigations, only few torsade events were included and/or rarely were postdose heart rate corrected QT (QTc) measurements included, as a surrogate of drug exposure. We developed a multivariate logistic regression model using data from 22,214 patients (33% women) with 84 torsade events (56% women) to evaluate the relationship between risk factors for torsade using data from four anti-arrhythmic drug development programs...
December 8, 2017: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29219132/assessment-of-the-performance-of-community-directed-treatment-with-ivermectin-strategy-for-the-control-and-elimination-of-onchocerciasis-in-edo-state-nigeria
#18
Amenze Oritsemofe Onowhakpor, Obehi Hilda Okojie, Victoria A Wagbatsoma
BACKGROUND: Community-directed treatment with ivermectin (CDTI) was developed in the mid 1990's as a solution for the control and elimination of onchocerciasis. It requires that ivermectin be administered continuously over a period of at least 14 years with community involvement before elimination can be achieved. OBJECTIVES: The objective of this study is to assess the performance of CDTI strategy for control and elimination of onchocerciasis in endemic Local Government areas of Edo State...
October 2017: Indian Journal of Public Health
https://www.readbyqxmd.com/read/29219131/status-of-early-childhood-education-under-integrated-child-development-services-scheme-in-bankura-municipality-west-bengal
#19
Sumana Samanta, Subhra Samujjwal Basu, Dibakar Haldar, Aditya Prasad Sarkar, Asit Baran Saren, Gautam Narayan Sarkar
BACKGROUND: Early childhood education (ECE) is an important service provided by Integrated Child Development Services (ICDS). It is largely responsible for developing school readiness in children. OBJECTIVE: The objective of this study is to assess ECE component of ICDS services through measurement of school readiness and find out other correlates. METHODS: A cross-sectional evaluation study was carried out among Anganwadi centers (AWCs) under Bankura Municipality, West Bengal, India from July to November 2015...
October 2017: Indian Journal of Public Health
https://www.readbyqxmd.com/read/29219002/relationship-between-personality-traits-generativity-and-life-satisfaction-in-individuals-attending-university-programs-for-seniors
#20
Ana Belen Navarro-Prados, Sara Serrate-Gonzalez, Jose-Manuel Muñoz-Rodríguez, Unai Díaz-Orueta
Personality traits of older adults and their contribution to life satisfaction and generative interest were assessed. A total of 342 older participants (66% women), mean age = 67.89 years old ( SD = 6.52, range = 55-84 years old), who attended the University of the Experience in Salamanca (Spain), were evaluated. Information on sociodemographic data, perceived health and activity, personality traits, generativity, and life satisfaction was collected using self-reported questionnaires. Results confirmed a relation between personality traits, life satisfaction, and generativity...
January 1, 2017: International Journal of Aging & Human Development
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