Mildred López, Gabriela Huelgas, Mario Sánchez, Adalid Armenta, Angel Mendoza, José Daniel Lozada-Ramírez, Cecilia Anaya de Parrodi
We synthesized six new camphor-derived homochiral thioureas 1 - 6 , from commercially available (1 R )-(-)-camphorquinone. These new compounds 1 - 6 were evaluated as asymmetric organocatalysts in the stereoselective formation of glycosidic bonds, with 2,3,4,6-tetra- O -benzyl-D-glucopyranosyl and 2,3,4,6-tetra- O -benzyl-D-galactopyranosyl trichloroacetimidates as donors, and several alcohols as glycosyl acceptors, such as methanol, ethanol, 1-propanol, 1-butanol, 1-octanol, iso -propanol, tert -butanol, cyclohexanol, phenol, 1-naphtol, and 2-naphtol...
February 9, 2024: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry