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https://www.readbyqxmd.com/read/29679897/the-role-of-eveningness-in-obsessive-compulsive-symptoms-cross-sectional-and-prospective-approaches
#1
Rebecca C Cox, Breanna Tuck, Bunmi O Olatunji
BACKGROUND: Eveningness may be defined as the tendency to be most active and alert during the evening. Previous research has linked eveningness with maladaptive psychological outcomes, and recent evidence has highlighted circadian dysregulation as a novel factor in psychopathology, including obsessive-compulsive disorder (OCD). However, limited research has examined the unique relationship between eveningness and OC symptoms. Two studies were conducted to thoroughly examine the links between eveningness and OC symptoms, while also considering the role of depression symptoms and sleep-related factors...
April 6, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29679896/treatment-as-usual-tau-as-a-control-condition-in-trials-of-cognitive-behavioural-based-psychotherapy-for-self-harm-impact-of-content-and-quality-on-outcomes-in-a-systematic-review
#2
REVIEW
Katrina Witt, Daniela Pache de Moraes, Tatiana Taylor Salisbury, Ella Aren S Man, David Gunnell, Philip Hazell, Ellen Townsend, Kees van Heeringen, Keith Hawton
BACKGROUND: Randomized controlled trials (RCTs) are the mainstay of evaluations of the efficacy of psychosocial interventions. In a recent Cochrane systematic review we analysed the efficacy of cognitive behavioural-based psychotherapies compared to treatment as usual (TAU) in adults who self-harm. In this study we examine the content and reporting quality of TAU in these trials and their relationship to outcomes. METHODS: Five electronic databases (CCDANCTR-Studies and References, CENTRAL, MEDLINE, EMBASE, and PsycINFO) were searched for RCTs, indexed between 1 January 1998 and 30 April 2015, of cognitive-behavioural interventions compared to TAU for adults following a recent (within six months) episode of self-harm...
April 4, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29679873/disentangling-the-mental-health-impact-of-childhood-abuse-and-neglect-a-replication-and-extension-study-in-a-brazilian-sample-of-high-risk-youth
#3
Irismar Reis de Oliveira, Ana Cristina Matos-Ragazzo, Yuning Zhang, Nina Maia Vasconcelos, Michella Lopes Velasquez, Daniela Reis, Monica Gonçalves Ribeiro, Marina Monzani da Rocha, Maria Conceição Rosario, Paul Stallard, Charlotte A M Cecil
Childhood maltreatment is a key predictor of mental health problems across the life span. Yet, how maltreatment types independently and jointly influence the risk for psychiatric problems remains unclear. The aim of the study was two-fold: first, to replicate recent findings regarding the impact of maltreatment types on youth psychiatric symptoms, based on a Brazilian sample of high-risk adolescents (n = 347; age range = 11-17 yrs), and second, to extend existing findings by examining whether this relationship is mediated by bullying victimization and/or perpetration...
April 18, 2018: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29679849/global-analysis-of-advanced-metastatic-breast-cancer-decade-report-2005-2015
#4
Fatima Cardoso, Danielle Spence, Shirley Mertz, Dian Corneliussen-James, Kimberly Sabelko, Julie Gralow, Maria-João Cardoso, Fedro Peccatori, Diego Paonessa, Ann Benares, Naomi Sakurai, Marc Beishon, Sarah-Jane Barker, Musa Mayer
Approximately 0.5 million people worldwide die from metastatic breast cancer (mBC) every year. This manuscript provides an overview on the status of mBC in several regions of the world, highlighting the gaps in care, resources, and support available for patients with mBC. Primary research was conducted in 2015 and 2016, comprising four global qualitative and quantitative surveys of approximately 15,000 individuals in 34 countries. Secondary research was conducted using literature reviews of peer-reviewed publications, patient survey reports, and media or online articles...
April 18, 2018: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29679657/eleven-loci-with-new-reproducible-genetic-associations-with-allergic-disease-risk
#5
Manuel Ar Ferreira, Judith M Vonk, Hansjörg Baurecht, Ingo Marenholz, Chao Tian, Joshua D Hoffman, Quinta Helmer, Annika Tillander, Vilhelmina Ullemar, Yi Lu, Franz Rüschendorf, David A Hinds, Norbert Hübner, Stephan Weidinger, Patrik Ke Magnusson, Eric Jorgenson, Young-Ae Lee, Dorret I Boomsma, Robert Karlsson, Catarina Almqvist, Gerard H Koppelman, Lavinia Paternoster
BACKGROUND: A recent genome-wide association study (GWAS) identified 99 loci that contain genetic risk variants shared between asthma, hay fever and eczema. Many more risk loci shared between these common allergic diseases remain to be discovered, which could point to new therapeutic opportunities. OBJECTIVE: To identify novel risk loci shared between asthma, hay fever and eczema by applying a gene-based test of association to results from a published GWAS that included data from 360,838 individuals...
April 18, 2018: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29679617/retinopathy-of-prematurity-a-review-of-risk-factors-and-their-clinical-significance
#6
REVIEW
Sang Jin Kim, Alexander D Port, Ryan Swan, J Peter Campbell, R V Paul Chan, Michael F Chiang
Retinopathy of prematurity (ROP) is a retinal vasoproliferative disease that affects premature infants. Despite improvements in neonatal care and management guidelines, ROP remains a leading cause of childhood blindness worldwide. Current screening guidelines are primarily based on two risk factors: birth weight and gestational age; however, many investigators have suggested other risk factors, including maternal factors, prenatal and perinatal factors, demographics, medical interventions, comorbidities of prematurity, nutrition, and genetic factors...
April 19, 2018: Survey of Ophthalmology
https://www.readbyqxmd.com/read/29679604/outdoor-play-and-nature-connectedness-as-potential-correlates-of-internalized-mental-health-symptoms-among-canadian-adolescents
#7
Caroline Piccininni, Valerie Michaelson, Ian Janssen, William Pickett
Exposures to outdoor environments have great potential to be protective factors for the mental health of young people. In a national analysis of Canadian adolescents, we explored how such exposures, as well as self-perceptions of connectedness with nature, each related to the prevalence of recurrent psychosomatic symptoms. The data source for this cross-sectional study, consisting of a weighted sample of 29,784 students aged 11-15 years from 377 schools, was the 2013/2014 cycle of the Health Behaviour in School-aged Children (HBSC) study...
April 18, 2018: Preventive Medicine
https://www.readbyqxmd.com/read/29679573/circrna-expression-analysis-in-lung-adenocarcinoma-comparison-of-paired-fresh-frozen-and-formalin-fixed-paraffin-embedded-specimens
#8
Fan Zhang, Xing Zhao, Hongyan Dong, Jianzhen Xu
Circular RNA (circRNAs) is a novel class of endogenous non-coding RNAs which is widely involved in carcinogenesis. Archived formalin-fixed paraffin-embedded (FFPE) specimens represent valuable resources for cancer research. Currently there is a lack of systematic analysis on the feasibility of circRNAs expression analysis using FFPE samples. Here, we reported the first comparison study of circRNA expression from paired fresh frozen and FFPE specimens of lung adenocarcinoma. circRNAs expression of paired lung adenocarcinoma and adjacent normal samples, starting from either fresh frozen or FFPE materials, were analyzed via a high-throughput circRNA microarray...
April 18, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29679443/a-20-year-review-the-use-of-exception-from-informed-consent-and-waiver-of-informed-consent-in-emergency-research
#9
Lauren Klein, Johanna Moore, Michelle Biros
BACKGROUND: Due to the acuity and time sensitive needs of their clinical condition, patients presenting with certain emergent pathologies may lack capacity to provide meaningful prospective informed consent to participate in clinical research. For these reasons, these populations have often been excluded from research investigations. To mitigate this, regulations allowing Exception from Informed Consent (EFIC) (21 CFR 50.24) or Waiver of Informed Consent (WIC) (45 CFR 46.101) were developed in 1996...
April 21, 2018: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/29679414/rates-and-features-of-methamphetamine-related-presentations-to-emergency-departments-an-integrative-literature-review
#10
REVIEW
Rikki Jones, Cindy Woods, Kim Usher
AIMS AND OBJECTIVES: To review the clinical impact methamphetamine has on emergency departments (ED) by assessing the available research on the rates and features of methamphetamine-related presentations. BACKGROUND: Globally, methamphetamine availability, distribution and use has rapidly increased. As a result, the number of methamphetamine-related presentations to EDs has also increased. In this context, it is timely to review the rate and features of methamphetamine-related presentations to understand the impact of methamphetamine on EDs and facilitate the allocation of services, staff and resources...
April 20, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29679367/a-systematic-review-of-the-quality-of-reporting-of-simulation-studies-about-methods-for-the-analysis-of-complex-longitudinal-patient-reported-outcomes-data
#11
REVIEW
Aynslie M Hinds, Tolulope T Sajobi, Véronique Sebille, Richard Sawatzky, Lisa M Lix
PURPOSE: This study describes the characteristics and quality of reporting for published computer simulation studies about statistical methods to analyze complex longitudinal (i.e., repeated measures) patient-reported outcomes (PROs); we included methods for longitudinal latent variable measurement and growth models and response shift. METHODS: Scopus, PsycINFO, PubMed, EMBASE, and Social Science Citation Index were searched for English-language studies published between 1999 and 2016 using selected keywords...
April 20, 2018: Quality of Life Research
https://www.readbyqxmd.com/read/29679206/injury-prevention-and-return-to-play-strategies-in-elite-football-no-consent-between-players-and-team-coaches
#12
Oliver Loose, Leonard Achenbach, Birgit Fellner, Jennifer Lehmann, Petra Jansen, Michael Nerlich, Peter Angele, Werner Krutsch
INTRODUCTION: Injuries are a common problem in football. To improve prevention strategies, the players' (p) and coaches' (c) views need to be disclosed as they have a strong impact on return to play decisions. The aim of this study is to reveal current opinions with regard to injury prevention and return to play strategies to introduce new strategies in elite football. MATERIALS AND METHODS: In a retrospective data analysis of elite salaried football players (n = 486) and team coaches (n = 88), a detailed investigation by means of a standardized questionnaire was carried out...
April 20, 2018: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/29679192/the-disclosure-of-celebrity-major-depressive-disorder-diagnoses-in-hong-kong-its-effects-on-public-awareness-and-understanding-toward-the-illness
#13
Vivienne S Y Leung
This paper aims to examine consumer perception toward celebrity diagnoses of major depressive disorder (MDD) in Hong Kong and to provide insights into the effect of various factors on the persuasive effectiveness of MDD communication. A total of thirty-five interviews were conducted in April 2015. Interviewees in general are aware of celebrity MDD diagnoses, but they do not deem MDD as a threat to themselves. Hence, they are not motivated to learn more about the symptoms. Responses to celebrity MDD diagnoses are mixed...
April 21, 2018: Community Mental Health Journal
https://www.readbyqxmd.com/read/29679164/the-effect-of-a-school-based-intervention-on-physical-activity-and-well-being-a-non-randomised-controlled-trial-with-children-of-low-socio-economic-status
#14
Stephen Shannon, Deirdre Brennan, Donncha Hanna, Zoe Younger, Jessica Hassan, Gavin Breslin
BACKGROUND: Self-determination theory (SDT) has been used to predict children's physical activity and well-being. However, few school-based SDT intervention studies have been conducted, and no research exists with children of low socio-economic status (SES). Therefore, SDT-derived needs-supportive teaching techniques informed the design and analyses of the Healthy Choices Programme (HCP). The aim was to determine if the HCP could enhance moderate-to-vigorous physical activity (MVPA) and well-being among children of low SES through increasing autonomy-support, needs satisfaction and intrinsic motivation...
April 20, 2018: Sports Medicine—Open
https://www.readbyqxmd.com/read/29679132/-self-reported-vision-in-gerontological-health-services-research-and-practice-an-opening-plea
#15
REVIEW
J Köberlein-Neu, A Seifert, I Himmelsbach
The use of self-reported vision is an integral part of most population surveys and is primarily used for healthcare monitoring. Since the patient's assessment is not always consistent with the objectively measured clinical parameters, the majority of the literature looks critically at the adequacy of self-reported vision, particularly with respect to answering epidemiological questions; however, it is often misunderstood that self-reported vision measures far more than the directly derived information show...
April 20, 2018: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29679100/g-spotplasty-a-new-surgical-plastic-intervention-the-preliminary-study
#16
Adam Ostrzenski
BACKGROUND: Ostrzenski's G-pot anatomical structure discovery has been verified by the anatomy, histology, MRI in vivo, and electrovaginography in vivo studies. The objectives of this scientific-clinical investigation were to develop a new surgical reconstructive intervention (G-spotplasty); to determine the ability of G-spotplasty surgical implementation; to observe for potential complications; and to gather initial information on whether G-spotplasty improves female sexual activity, sexual behaviors, and sexual concerns...
April 20, 2018: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/29679097/quantitative-trait-loci-qtls-for-water-use-and-crop-production-traits-co-locate-with-major-qtl-for-tolerance-to-water-deficit-in-a-fine-mapping-population-of-pearl-millet-pennisetum-glaucum-l-r-br
#17
Murugesan Tharanya, Jana Kholova, Kaliamoorthy Sivasakthi, Deepmala Seghal, Charles Tom Hash, Basker Raj, Rakesh Kumar Srivastava, Rekha Baddam, Thiyagarajan Thirunalasundari, Rattan Yadav, Vincent Vadez
Four genetic regions associated with water use traits, measured at different levels of plant organization, and with agronomic traits were identified within a previously reported region for terminal water deficit adaptation on linkage group 2. Close linkages between these traits showed the value of phenotyping both for agronomic and secondary traits to better understand plant productive processes. Water saving traits are critical for water stress adaptation of pearl millet, whereas maximizing water use is key to the absence of stress...
April 21, 2018: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
https://www.readbyqxmd.com/read/29678991/measurement-properties-of-the-health-of-the-nation-outcome-scales-honos-family-of-measures-protocol-for-a-systematic-review
#18
Meredith G Harris, Claudia Sparti, Roman Scheurer, Tim Coombs, Jane Pirkis, Torleif Ruud, Steve Kisely, Ketil Hanssen-Bauer, Johan Siqveland, Philip M Burgess
INTRODUCTION: The Health of the Nation Outcome Scales (HoNOS) for adults, and equivalent measures for children and adolescents and older people, are widely used in clinical practice and research contexts to measure mental health and functional outcomes. Additional HoNOS measures have been developed for special populations and applications. Stakeholders require synthesised information about the measurement properties of these measures to assess whether they are fit for use with intended service settings and populations and to establish performance benchmarks...
April 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29678990/chemoattractant-receptor-homologous-molecule-expressed-on-th2-cells-crth2-antagonists-in-asthma-a-systematic-review-and-meta-analysis-protocol
#19
Wei Liu, Jie Min, Hongli Jiang, Bing Mao
INTRODUCTION: More than 20 orally bioavailable chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) antagonists have moved forward to clinical development in recent years for the treatment of asthma. However, evidence from individual randomised controlled trials (RCTs) has demonstrated inconsistent results in their efficacy and safety. METHODS AND ANALYSIS: PubMed/Medline, Embase, Web of Science, Cochrane Database of Systematic Reviews, Global Index Medicus, Cochrane Central Register of Controlled Trials and Scopus will be searched from inception to 30 December 2017 for eligible RCTs, with additional studies being identified by manual searches...
April 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29678973/involving-the-public-in-epidemiological-public-health-research-a-qualitative-study-of-public-and-stakeholder-involvement-in-evaluation-of-a-population-wide-natural-policy-experiment
#20
Rachel Anderson de Cuevas, Lotta Nylén, Bo Burström, Margaret Whitehead
BACKGROUND: Public involvement in research is considered good practice by European funders; however, evidence of its research impact is sparse, particularly in relation to large-scale epidemiological research. OBJECTIVES: To explore what difference public and stakeholder involvement made to the interpretation of findings from an evaluation of a natural policy experiment to influence the wider social determinants of health: 'Flexicurity'. SETTING: Stockholm County, Sweden...
April 20, 2018: BMJ Open
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