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https://www.readbyqxmd.com/read/29691994/chemical-biochemical-preclinical-and-clinical-studies-of-ganoderma-lucidum-polysaccharide-as-an-approved-drug-for-treating-myopathy-and-other-diseases-in-china
#1
REVIEW
Pengjiao Zeng, Zhihua Guo, Xuan Zeng, Cui Hao, Yiran Zhang, Meng Zhang, Yong Liu, Hui Li, Juan Li, Lijuan Zhang
Ganoderma lucidum is an edible medicinal mushroom known as "Lingzhi" in China and "Reishi or Manetake" in Japan. It is a highly prized vitality-enhancing herb for more than 2000 years. G. lucidum polysaccharide (GLPS) has been identified as one of the major bioactive components and developed into a drug named "Ji 731 Injection" in China since 1973. The large-scale production of the drug began in 1985 and approved by the Chinese FDA as "Polysaccharidum of G. lucidum Karst Injection" (Ling Bao Duo Tang Zhu She Ye) in 2000, which is applied intramuscularly...
April 24, 2018: Journal of Cellular and Molecular Medicine
https://www.readbyqxmd.com/read/29691977/focal-species-candidates-for-pesticide-risk-assessment-in-european-rice-fields-a-literature-review
#2
REVIEW
Martin Vallon, Christian Dietzen, Silke Laucht, Jan-Dieter Ludwigs
An assessment of potential risks of pesticides on wildlife is required during the process of product registration within Europe, because of the importance of agricultural landscapes as wildlife habitats. Despite their peculiarity and their specific role as artificial wetlands, rice paddies are to date pooled with cereals in guidance documents on how to conduct risk assessments for birds and mammals in Europe. Hence, the focal species currently considered in risk assessments for rice paddies are those known from cereal fields and can therefore be expected to differ significantly from the species actually occurring in the wet environments of rice paddies...
April 25, 2018: Integrated Environmental Assessment and Management
https://www.readbyqxmd.com/read/29691962/gastrointestinal-symptoms-in-children-primary-care-and-specialist-interface
#3
REVIEW
Valeria Dipasquale, Domenico Corica, Simone M C Gramaglia, Simona Valenti, Claudio Romano
AIMS: Gastrointestinal symptoms and diseases represent one of the major reasons for paediatricians' requests for specialist consultations and hospital admissions. One fourth of annual medical consultations for children younger than 6 years can be attributed to gastrointestinal symptoms. High-quality guidelines have been validated worldwide to provide clinical recommendations and support healthcare providers' practice. Nevertheless, overall compliance to standards of care is unsatisfactory, and children with gastrointestinal symptoms frequently undergo expensive, useless specialist consultations and laboratory evaluations...
April 24, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29691957/very-long-term-outcome-of-schizophrenia
#4
REVIEW
Jan Volavka, Jan Vevera
PURPOSE: The principal aim is to review recent data concerning the very long-term outcome of schizophrenia and schizophrenia spectrum disorders. We examine factors that influence outcome, including therapeutic interventions. METHOD: PubMed and Scopus databases were searched for papers published between 2008 and 2017 reporting on prospective studies of schizophrenia or schizophrenia spectrum with a follow-up period ≥5 years with adequate outcome information. Additional publications were found in reference lists and authors' reference libraries...
April 24, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29691955/pharmacist-led-discharge-medication-counselling-a-scoping-review
#5
REVIEW
Aline F Bonetti, Wálleri C Reis, Natália Fracaro Lombardi, Antonio M Mendes, Harli Pasquini Netto, Inajara Rotta, Fernando Fernandez-Llimos, Roberto Pontarolo
RATIONALE, AIMS, AND OBJECTIVES: Discharge medication counselling has produced improved quality of care and health outcomes, especially by reducing medication errors and readmission rates, and improving medication adherence. However, no studies have assembled an evidence-based discharge counselling process for clinical pharmacists. Thus, the present study aims to map the components of the pharmacist-led discharge medication counselling process. METHODS: We performed a scoping review by searching electronic databases (Pubmed, Scopus, and DOAJ) and conducting a manual search to identify studies published up to July 2017...
April 24, 2018: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/29691950/adapting-evidence-based-clinical-practice-guidelines-at-university-teaching-hospitals-a-model-for-the-eastern-mediterranean-region
#6
Yasser S Amer, Hayfaa A Wahabi, Manal M Abou Elkheir, Ghada A Bawazeer, Shaikh M Iqbal, Maher A Titi, Aishah Ekhzaimy, Khalid A Alswat, Rasmieh A Alzeidan, Lubna A Al-Ansary
RATIONALE, AIMS, AND OBJECTIVES: Clinical practice guidelines (CPGs) are significant tools for evidence-based health care quality improvement. The CPG program at King Saud University was launched as a quality improvement program to fulfil the international accreditation standards. This program was a collaboration between the Research Chair for Evidence-Based Healthcare and Knowledge Translation and the Quality Management Department. This study aims to develop a fast-track method for adaptation of evidence-based CPGs and describe results of the program...
April 24, 2018: Journal of Evaluation in Clinical Practice
https://www.readbyqxmd.com/read/29691914/definitions-for-warning-signs-and-signs-of-severe-dengue-according-to-the-who-2009-classification-systematic-review-of-literature
#7
REVIEW
Mostafa Ebraheem Morra, Ahmed M A Altibi, Somia Iqtadar, Le Huu Nhat Minh, Sameh Samir Elawady, Asma Hallab, Abdelrahman Elshafay, Omer Abedlbagi Omer, Ahmed Iraqi, Purushottam Adhikari, Jonair Hussein Labib, Khaled Mosaad Elhusseiny, Ahmed Elgebaly, Sophie Yacoub, Le Thi Minh Huong, Kenji Hirayama, Nguyen Tien Huy
Since warning signs and signs of severe dengue are defined differently between studies, we conducted a systematic review on how researchers defined these signs. We conducted an electronic search in Scopus to identify relevant articles, using key words including dengue, "warning signs," "severe dengue," and "classification." A total of 491 articles were identified through this search strategy and were subsequently screened by 2 independent reviewers for definitions of any of the warning or severe signs in the 2009 WHO dengue classification...
April 24, 2018: Reviews in Medical Virology
https://www.readbyqxmd.com/read/29691880/early-postnatal-growth-and-neurodevelopment-in-children-born-moderately-preterm-or-small-for-gestational-age-at-term-a-systematic-review
#8
REVIEW
Marion Taine, Marie-Aline Charles, Jacques Beltrand, Jean Christophe Rozé, Juliane Léger, Jérémie Botton, Barbara Heude
BACKGROUND: Clinicians' interest in the long-term effects of early postnatal growth (EPG) is growing. There is compelling evidence linking rapid EPG with later cardiovascular risk, but its neurodevelopmental benefits still remain hypothetical in individuals born moderately preterm (MP) or small for gestational at term (SGAT). METHODS: The objective was to perform a systematic review of the relationship between EPG before age 3 years and neurodevelopmental outcome for individuals born MP (32-36 weeks' gestational age) or SGAT...
April 25, 2018: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/29691868/de-implementation-a-concept-analysis
#9
Michele J Upvall, Annette M Bourgault
AIM: The purpose of this concept analysis is to explore the meaning of de-implementation and provide a definition that can be used by researchers and clinicians to facilitate evidence-based practice. BACKGROUND: De-implementation is a relatively unknown process overshadowed by the novelty of introducing new ideas and techniques into practice. Few studies have addressed the challenge of de-implementation and the cognitive processes involved when terminating harmful or unnecessary practices...
April 25, 2018: Nursing Forum
https://www.readbyqxmd.com/read/29691835/rufinamide-add-on-therapy-for-refractory-epilepsy
#10
REVIEW
Mariangela Panebianco, Hemanshu Prabhakar, Anthony G Marson
BACKGROUND: Epilepsy is a central nervous system disorder (neurological disorder). Epileptic seizures are the result of excessive and abnormal cortical nerve cell electrical activity in the brain. Despite the development of more than 10 new antiepileptic drugs (AEDs) since the early 2000s, approximately a third of people with epilepsy remain resistant to pharmacotherapy, often requiring treatment with a combination of AEDs. In this review, we summarised the current evidence regarding rufinamide, a novel anticonvulsant medication, which, as a triazole derivative, is structurally unrelated to any other currently used anticonvulsant medication, when used as an add-on treatment for refractory epilepsy...
April 25, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29691754/the-effect-of-total-hip-arthroplasty-on-sports-and-work-participation-a-systematic-review-and-meta-analysis
#11
REVIEW
Alexander Hoorntje, Kim Y Janssen, Stefan B T Bolder, Koen L M Koenraadt, Joost G Daams, Leendert Blankevoort, Gino M M J Kerkhoffs, P Paul F M Kuijer
BACKGROUND: Total hip arthroplasty (THA) is a successful procedure to treat end-stage hip osteoarthritis. The procedure is increasingly performed in adults of working age, who often wish to return to sports (RTS) and return to work (RTW). However, a systematic overview of the evidence on RTS and RTW after THA is lacking. OBJECTIVES: Our aim was to systematically review (1) the extent to which patients RTS and RTW after THA, including (2) the time to RTS and RTW...
April 24, 2018: Sports Medicine
https://www.readbyqxmd.com/read/29691595/-environment-and-the-health-in-all-policies-approach-an-overview
#12
REVIEW
Hajo Zeeb, Henk Hilderink, Sarah Forberger
BACKGROUND: One quarter of the global disease burden could be avoided with management strategies for environmental risk factors such as air and water pollution, food contamination, injuries and poor road safety. Many decisions influencing health are made outside the health sector; thus, the joint consideration and implementation of health and environmental factors in the relevant policies are becoming increasingly important. MATERIALS AND METHODS: By means of a selective literature search, we identified important policy documents and selected research articles as a basis for the introduction and current discussion of the Health in All Policies (HiAP) approach...
April 24, 2018: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/29691587/usability-of-validated-sleep-assessment-questionnaires-in-patients-with-chronic-pruritus-an-interview-based-study
#13
Theresa Suilmann, Claudia Zeidler, Nani Osada, Claudia Riepe, Sonja Ständer
Impaired sleep due to nocturnal pruritus is a common symptom in patients with chronic pruritus. However, there is no standardized, simplified instrument for assessing sleep-related problems in patients with chronic pruritus. After a literature search, we conducted 50 interviews with patients with chronic pruritus and tested 12 items most frequently used in routine sleep questionnaires. Afterwards, 2 sleep assessment questionnaires (Pittsburgh Sleep Quality Index; Regensburg Insomnia Scale) were selected for use in 88 patients with chronic pruritus with sleep impairment due to pruritus...
April 24, 2018: Acta Dermato-venereologica
https://www.readbyqxmd.com/read/29691570/-outcome-of-one-visit-and-multiple-visit-root-canal-treatment-for-cracked-tooth-with-pulpitis-a-meta-analysis
#14
Wen Wang, Peng-Lai Wang, Ni-Na Xie, Cui Wu, Zong-Xiang Liu
PURPOSE: To compare the treatment effect between one-visit and multiple-visit endodontic treatment for cracked tooth with pulpitis. METHODS: The literatures published before 2016-06-01 regarding to one-visit and multiple-visit root canal treatment for cracked tooth with pulpitis were searched through MEDLINE, CNKI, VIP, Wanfang Database et al. Then the included studies were chosen according to the inclusion criteria. Collection of features, quality evaluation and analysis of treatment effect, follow-up results (half year/1 year) and postoperative pain of the included studies were analyzed using Stata/SE12...
December 2017: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
https://www.readbyqxmd.com/read/29691330/cortical-mechanisms-of-prioritizing-selection-for-rejection-in-visual-search
#15
Sarah E Donohue, Mandy V Bartsch, Hans-Jochen Heinze, Mircea A Schoenfeld, Jens-Max Hopf
In visual search, the more one knows about a target, the faster one can find it. Surprisingly, target identification is also faster with knowledge about distractor-features. The latter is paradoxical, as it implies that to avoid the selection of an item, the item must somehow be selected to some degree. This conundrum has been termed the 'ignoring paradox,' and, to date, little is known about how the brain resolves it. Here, in data from four experiments using neuromagnetic brain recordings in male and female humans, we provide evidence that this paradox is resolved by giving distracting information priority in cortical processing...
April 24, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29691308/context-dependency-of-in-flight-responses-by-manduca-sexta-moths-to-ambient-differences-in-relative-humidity
#16
Michael S Wolfin, Robert A Raguso, Goggy Davidowitz, Joaquin Goyret
The use of sensory information to control behavior usually involves the integration of sensory input from different modalities. This integration is affected by behavioral states and experience, and it is also sensitive to the spatiotemporal patterns of stimulation and other general contextual cues. Following the finding that hawkmoths can use relative humidity (RH) as a proxy for nectar content during close-range foraging, we evaluate here whether RH could be used during locomotive flight under two simulated contexts in a wind tunnel: 1) dispersion, and 2) search phase of the foraging behavior...
April 24, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29691216/the-usability-and-effectiveness-of-mobile-health-technology-based-lifestyle-and-medical-intervention-apps-supporting-health-care-during-pregnancy-systematic-review
#17
REVIEW
Sanne B Overdijkink, Adeline V Velu, Ageeth N Rosman, Monique Dm van Beukering, Marjolein Kok, Regine Pm Steegers-Theunissen
BACKGROUND: A growing number of mobile health (mHealth) technology-based apps are being developed for personal lifestyle and medical health care support, of which several apps are related to pregnancy. Evidence on usability and effectiveness is limited but crucial for successful implementation. OBJECTIVE: This study aimed to evaluate the usability, that is, feasibility and acceptability, as well as effectiveness of mHealth lifestyle and medical apps to support health care during pregnancy in high-income countries...
April 24, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29691214/mobile-health-initiatives-in-vietnam-scoping-study
#18
Jeffrey A Lam, Linh Thuy Dang, Ngoc Tran Phan, Hue Thi Trinh, Nguyen Cong Vu, Cuong Kieu Nguyen
BACKGROUND: Mobile health (mHealth) offers a promising solution to the multitude of challenges the Vietnamese health system faces, but there is a scarcity of published information on mHealth in Vietnam. OBJECTIVE: The objectives of this scoping study were (1) to summarize the extent, range, and nature of mHealth initiatives in Vietnam and (2) to examine the opportunities and threats of mHealth utilization in the Vietnamese context. METHODS: This scoping study systematically identified and extracted relevant information from 20 past and current mHealth initiatives in Vietnam...
April 24, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29691188/medicinal-plants-from-the-brazilian-amazonian-region-and-their-antileishmanial-activity-a-review
#19
REVIEW
Bruno José Martins Da Silva, Amanda Anastácia Pinto Hage, Edilene Oliveira Silva, Ana Paula Drummond Rodrigues
Leishmaniasis, a neglected disease caused by Leishmania protozoans, primarily affects people in tropical and subtropical areas. Chemotherapy based on the use of pentavalent antimonials, amphotericin B, paromomycin, miltefosine and liposomal amphotericin B is currently the only effective treatment. However, adverse effects, long-term treatment and the emergence of parasite resistance have led to the search for alternative treatments. Natural products used in traditional medicine provide an unlimited source of molecules for the identification of new drugs, and the Amazon region has abundant biodiversity that includes several species of plants and animals, providing a rich source of new products and compounds...
April 12, 2018: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/29690969/molecular-pathogenesis-of-chewable-tobacco
#20
Saeeda Baig, Zile Rubab, Wasfa Farooq
In Pakistan, extensive use of several precarious chewable tobacco formulations has made oral cancer the second leading malignancy. Selection of literature was done by a survey of studies published from 1990 to 2017 mainly, from PUBMED and few from other search engines, on naswar, gutka, areca nut and betel quid, which included published reviews, original articles and other data sources on chewable tobacco, its epidemiology, pathological implications, and psychological effects. These studies have revealed that the chemicals in these formulations bind and mutate DNA of oral mucosa through down regulating cellular repair pathways and upregulating genetic networks associated with pathogenesis...
May 2018: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
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