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https://www.readbyqxmd.com/read/28922753/effects-of-periodic-photoinhibitory-light-exposure-on-physiology-and-productivity-of-arabidopsis-plants-grown-under-low-light
#1
Yonglan Tian, Joanna Sacharz, Maxwell A Ware, Huayong Zhang, Alexander V Ruban
This work examined the long-term effects of periodic high light stress on photosynthesis, morphology, and productivity of low-light-acclimated Arabidopsis plants. Significant photoinhibition of Arabidopsis seedlings grown under low light (100 μmol photons m-2 s-1) was observed at the beginning of the high light treatment (three times a day for 30 min at 1800 μmol photons m-2 s-1). However, after 2 weeks of treatment, similar photosynthesis yields (Fv/Fm) to those of control plants were attained. The daily levels of photochemical quenching measured in the dark (qPd) indicated that the plants recovered from photoinhibition within several hours once transferred back to low light conditions, with complete recovery being achieved overnight...
July 10, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/28922372/reduction-of-organelle-motility-by-removal-of-potassium-and-other-solutes
#2
John W Murray, David Yin, Allan W Wolkoff
There are surprisingly few studies that describe how the composition of cell culture medium may affect the trafficking of organelles. Here we utilize time lapse multi-channel fluorescent imaging to show that short term exposure of Huh-7 cells to medium lacking potassium, sodium, or chloride strongly reduces but does not eliminate the characteristic back and forth and cell-traversing movement of fluorescent EGF (FL-EGF) containing organelles. We focused on potassium because of its relatively low abundance in media and serum and its energy requiring accumulation into cells...
2017: PloS One
https://www.readbyqxmd.com/read/28922279/translation-cross-cultural-adaptation-and-validation-of-the-farsi-version-of-nih-task-force-s-recommended-multidimensional-minimal-dataset-for-research-on-chronic-low-back-pain
#3
Pardis Noormohammadpour, Bahareh Tavana, Mohammad Ali Mansournia, Mehdi Zeinalizadeh, Babak Mirzashahi, Mohsen Rostami, Ramin Kordi
STUDY DESIGN: Translation and cultural adaptation of the National Institutes of Health (NIH) Task Force's minimal dataset. OBJECTIVE: The purpose of this study was to evaluate validity and reliability of the Farsi version of NIH Task Force's recommended multidimensional minimal dataset for research on chronic low back pain (CLBP). SUMMARY OF BACKGROUND DATA: Considering the high cost of CLBP and its increasing prevalence, NIH Pain Consortium developed research standards (including recommendations for definitions, a minimum dataset, and outcomes' report) for studies regarding CLBP...
September 15, 2017: Spine
https://www.readbyqxmd.com/read/28922049/magnitudes-of-muscle-activation-of-spine-stabilizers-in-healthy-adults-during-prone-on-elbow-planking-exercises-with-and-without-a-fitness-ball
#4
James W Youdas, Kendra C Coleman, Erin E Holstad, Stephanie D Long, Nicole L Veldkamp, John H Hollman
Prone planking exercises have been used by rehabilitation professionals to activate torso muscles in healthy persons and those with low back pain. The aim of this study was to compare the magnitude of electromyographic (EMG) muscle activation from 10 right-sided muscles as demonstrated by the percentage of maximum voluntary isometric contraction (%MVIC) during four planking procedures. Surface EMG activity was acquired from the following muscles: (1) iliocostalis lumborum (IL), (2) longissimus thoracis (LT), (3) lumbar multifidus (LM), (4) rectus abdominis (RA), (5) external oblique (EO), (6) internal oblique (IO), (7) serratus anterior (SA), (8) latissimus dorsi (LD), (9) hamstrings (HS), and (10) gluteus maximus (GM)...
September 18, 2017: Physiotherapy Theory and Practice
https://www.readbyqxmd.com/read/28921656/animal-models-for-studying-the-etiology-and-treatment-of-low-back-pain
#5
REVIEW
Changgui Shi, Sujun Qiu, Scott M Riester, Vaskar Das, Bingqian Zhu, Atiyayein A Wallace, Andre J van Wijnen, Fackson Mwale, James C Iatridis, Daisuke Sakai, Gina Votta-Velis, Wen Yuan, Hee-Jeong Im
Chronic low back pain is a major cause of disability and health care costs. Effective treatments are inadequate for many patients. Animal models are essential to further understanding of the pain mechanism and testing potential therapies. Currently, a number of preclinical models have been developed attempting to mimic aspects of clinical conditions that contribute to low back pain. This review focused on describing these animal models and the main behavioral tests for assessing pain in each model. Animal models of low back pain can be divided into the following five categories: discogenic low back pain, radicular back pain, facet joint osteoarthritis back pain, muscle-induced low back pain, and spontaneous occurring low back pain models...
September 18, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28920963/tuning-a-circular-p-n-junction-in-graphene-from-quantum-confinement-to-optical-guiding
#6
Yuhang Jiang, Jinhai Mao, Dean Moldovan, Massoud Ramezani Masir, Guohong Li, Kenji Watanabe, Takashi Taniguchi, Francois M Peeters, Eva Y Andrei
The photon-like propagation of the Dirac electrons in graphene, together with its record-high electronic mobility, can lead to applications based on ultrafast electronic response and low dissipation. However, the chiral nature of the charge carriers that is responsible for the high mobility also makes it difficult to control their motion and prevents electronic switching. Here, we show how to manipulate the charge carriers by using a circular p-n junction whose size can be continuously tuned from the nanometre to the micrometre scale...
September 18, 2017: Nature Nanotechnology
https://www.readbyqxmd.com/read/28920043/short-term-analgesic-effects-of-5-dextrose-epidural-injections-for-chronic-low-back-pain-a-randomized-controlled-trial
#7
Liza Maniquis-Smigel, Kenneth Dean Reeves, Howard Jeffrey Rosen, John Lyftogt, Cassie Graham-Coleman, An-Lin Cheng, David Rabago
BACKGROUND: Hypertonic dextrose injection (prolotherapy) is reported to reduce pain including non-surgical chronic low back pain (CLBP), and subcutaneous injection of 5% dextrose is reported to reduce neurogenic pain, hyperalgesia and allodynia. The mechanism in both cases is unclear, though a direct effect of dextrose on neurogenic pain has been proposed. This study assessed the short-term analgesic effects of epidural 5% dextrose injection compared with saline for non-surgical CLBP...
February 2017: Anesthesiology and Pain Medicine
https://www.readbyqxmd.com/read/28919811/response-to-duloxetine-in-chronic-low-back-pain-exploratory-post-hoc-analysis-of-a-japanese-phase-iii-randomized-study
#8
Toshinaga Tsuji, Naohiro Itoh, Mitsuhiro Ishida, Toshimitsu Ochiai, Shinichi Konno
PURPOSE: Duloxetine is efficacious for chronic low back pain (CLBP). This post hoc analysis of a Japanese randomized, placebo-controlled trial (ClinicalTrials.gov, NCT01855919) assessed whether patients with CLBP with early pain reduction or treatment-related adverse events of special interest (TR-AESIs; nausea, somnolence, constipation) have enhanced responses to duloxetine. PATIENTS AND METHODS: Patients (N = 456) with CLBP for ≥6 months and Brief Pain Inventory (BPI) average pain severity score of ≥4 were randomized (1:1) to duloxetine 60 mg/day or placebo for 14 weeks...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28919806/how-stable-are-quantitative-sensory-testing-measurements-over-time-report-on-10-week-reliability-and-agreement-of-results-in-healthy-volunteers
#9
Helen Nothnagel, Christian Puta, Thomas Lehmann, Philipp Baumbach, Martha B Menard, Brunhild Gabriel, Holger H W Gabriel, Thomas Weiss, Frauke Musial
BACKGROUND: Quantitative sensory testing (QST) is a diagnostic tool for the assessment of the somatosensory system. To establish QST as an outcome measure for clinical trials, the question of how similar the measurements are over time is crucial. Therefore, long-term reliability and limits of agreement of the standardized QST protocol of the German Research Network on Neuropathic Pain were tested. METHODS: QST on the lower back and hand dorsum (dominant hand) were assessed twice in 22 healthy volunteers (10 males and 12 females; mean age: 46...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28919156/chronic-low-back-pain-and-the-transdiagnostic-process-how-do-cognitive-and-emotional-dysregulations-contribute-to-the-intensity-of-risk-factors-and-pain
#10
M Le Borgne, A H Boudoukha, A Petit, Y Roquelaure
BACKGROUND AND AIMS: Based on a transdiagnostic approach, this study assesses the impact of cognitive and emotional processes (difficulties in emotional regulation, impulsiveness, rumination and somatosensory amplification) on the psychological risk factors of chronic low-back pain. METHODS: The study was carried out with 256 patients with chronic low-back pain. All the variables were assessed through a booklet of 10 validated questionnaires. Multiple regression analysis and moderation analysis were performed...
September 11, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/28919117/global-regional-and-national-incidence-prevalence-and-years-lived-with-disability-for-328-diseases-and-injuries-for-195-countries-1990-2016-a-systematic-analysis-for-the-global-burden-of-disease-study-2016
#11
(no author information available yet)
BACKGROUND: As mortality rates decline, life expectancy increases, and populations age, non-fatal outcomes of diseases and injuries are becoming a larger component of the global burden of disease. The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) provides a comprehensive assessment of prevalence, incidence, and years lived with disability (YLDs) for 328 causes in 195 countries and territories from 1990 to 2016. METHODS: We estimated prevalence and incidence for 328 diseases and injuries and 2982 sequelae, their non-fatal consequences...
September 16, 2017: Lancet
https://www.readbyqxmd.com/read/28919071/validation-of-the-retrieve-reverse-triage-events-criteria-for-same-day-return-of-non-st-elevation-acute-coronary-syndrome-patients-to-referring-non-pci-centres
#12
Sonya N Burgess, Vu Huynh Nguyen, James Xu, Yoshio Hinde, Anoop Dharmadmajan, Xavier Brennan, Karen Owen, Karen Lintern, Craig Juergens, Sidney Lo, Phong Nguyen, Krishna K Kadappu, John K French, Rohan Rajaratnam
BACKGROUND: There are continuing bed constraints in percutaneous coronary intervention centres (PCI) so efficient patient triage from referral hospitals is pivotal. To evaluate a strategy of PCI centre (PCIC) bed-sparing we examined return of patients to referral hospitals screened by the RETRIEVE (REverse TRIage EVEnts) criteria and validated its use as a tool for screening suitability for same day transfer of non-ST-elevation acute coronary syndrome (NSTEACS) patients post PCI to their referring non-PCI centre (NPCIC)...
August 19, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28918732/acupuncture-for-analgesia-in-the-emergency-department-a-multicentre-randomised-equivalence-and-non-inferiority-trial
#13
Marc M Cohen, De Villiers Smit, Nick Andrianopoulos, Michael Ben-Meir, David McD Taylor, Shefton J Parker, Chalie C Xue, Peter A Cameron
OBJECTIVES: This study aimed to assess analgesia provided by acupuncture, alone or in combination with pharmacotherapy, to patients presenting to emergency departments with acute low back pain, migraine or ankle sprain. DESIGN: A pragmatic, multicentre, randomised, assessor-blinded, equivalence and non-inferiority trial of analgesia, comparing acupuncture alone, acupuncture plus pharmacotherapy, and pharmacotherapy alone for alleviating pain in the emergency department...
June 19, 2017: Medical Journal of Australia
https://www.readbyqxmd.com/read/28918546/systemic-effects-of-repeated-intraocular-dexamethasone-intravitreal-implant-in-diabetic-patients-a-retrospective-study
#14
Alicia Valverde-Megías, Pilar Cifuentes-Canorea, Jorge Ruiz-Medrano, Pablo Peña-García, Alicia Megías-Fresno, Juan Donate-López, Julián García-Feijoo
INTRODUCTION: The objective of this study is to evaluate the influence of repeated intraocular dexamethasone implant (Ozurdex) injections on metabolic control in type 2 diabetic patients. METHODS: Retrospective study of 165 type 2 diabetic patients starting Ozurdex treatment who received no less than three consecutive injections. Glycated hemoglobin (HbA1c), serum creatinine, total cholesterol, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, and triglycerides (TGs) were evaluated during 15 months of follow-up after Ozurdex treatment onset...
September 16, 2017: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/28918003/relevance-of-adding-a-triangular-dynamic-cushion-on-a-traditional-chair-a-3d-analysis-of-seated-schoolchildren
#15
T Fettweis, M N Onkelinx, C Schwartz, C Demoulin, J L Croisier, M Vanderthommen
BACKGROUND: Low back pain is highly prevalent in the general population and is even reported as early as at primary school. A poor sitting position has been suggested as an etiologic factor. This study analysed, in primary schoolchildren, the influence of a triangular dynamic cushion that aims to help children maintain their physiological lumbar lordosis and to induce movement to reduce the static effect of the sitting position. METHODS: Thirty 8-year-old children took part in this study...
September 8, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28917523/medium-term-effects-of-kinesio-taping-in-patients-with-chronic-non-specific-low-back-pain-a-randomized-controlled-trial
#16
Amanda Costa Araujo, Patrícia do Carmo Silva Parreira, Luiz Carlos Hespanhol Junior, Tatiane Mota da Silva, Maurício Antônio da Luz Junior, Lucíola da Cunha Menezes Costa, Leonardo Oliveira Pena Costa
BACKGROUND: Kinesio taping is a commonly used intervention for patients with chronic low back pain. However, the medium term effects of kinesio taping in these patients are unknown. OBJECTIVE: To investigate the effectiveness of kinesio taping in patients with chronic low back pain after 6 months from randomization. METHODS: This was a randomized controlled trial with a 6 months follow up. One hundred and forty eight participants were randomly assigned to the experimental (kinesio taping with skin convolutions) or control (kinesio taping without convolutions-Sham Taping) group...
December 23, 2016: Physiotherapy
https://www.readbyqxmd.com/read/28917361/immediate-effects-of-pilates-based-therapeutic-exercise-on-postural-control-of-young-individuals-with-non-specific-low-back-pain-a-randomized-controlled-trial
#17
Susana Lopes, Christophe Correia, Gonçalo Félix, Mário Lopes, Ana Cruz, Fernando Ribeiro
OBJECTIVES: Low back pain affects the person's ability to keep balance, especially in challenging conditions. The purpose of this study was to determine the immediate effects of Pilates exercises on postural sway and dynamic balance of young individuals with non-specific low back pain. DESIGN: Controlled laboratory design. SETTINGS AND MAIN OUTCOME MEASURES: Forty-six participants with non-specific low back pain were randomized to a Pilates (n=23, 10 males; age: 21...
October 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28917154/neural-activation-in-stress-related-exhaustion-cross-sectional-observations-and-interventional-effects
#18
Hanna Malmberg Gavelin, Anna Stigsdotter Neely, Micael Andersson, Therese Eskilsson, Lisbeth Slunga Järvholm, Carl-Johan Boraxbekk
The primary purpose of this study was to investigate the association between burnout and neural activation during working memory processing in patients with stress-related exhaustion. Additionally, we investigated the neural effects of cognitive training as part of stress rehabilitation. Fifty-five patients with clinical diagnosis of exhaustion disorder were administered the n-back task during fMRI scanning at baseline. Ten patients completed a 12-week cognitive training intervention, as an addition to stress rehabilitation...
September 13, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28917134/the-development-of-the-dutch-version-of-the-fremantle-back-awareness-questionnaire
#19
Lotte Janssens, Nina Goossens, Benedict M Wand, Madelon Pijnenburg, Tinne Thys, Simon Brumagne
BACKGROUND: Disturbed body perception may play a role in the aetiology of chronic low back pain (LBP). The Fremantle Back Awareness Questionnaire (FreBAQ) is currently the only self-report questionnaire to assess back-specific body perception in individuals with LBP. OBJECTIVES: To perform a cross-cultural adaptation of the FreBAQ into Dutch. DESIGN: Psychometric study. METHODS: A Dutch version of the FreBAQ was generated through forward-backward translation, and was completed by 73 patients with LBP and 73 controls to assess discriminant validity...
September 7, 2017: Musculoskeletal Science & Practice
https://www.readbyqxmd.com/read/28915789/rapid-transcriptional-and-metabolic-regulation-of-the-deacclimation-process-in-cold-acclimated-arabidopsis-thaliana
#20
Majken Pagter, Jessica Alpers, Alexander Erban, Joachim Kopka, Ellen Zuther, Dirk K Hincha
BACKGROUND: During low temperature exposure, temperate plant species increase their freezing tolerance in a process termed cold acclimation. This is accompanied by dampened oscillations of circadian clock genes and disrupted oscillations of output genes and metabolites. During deacclimation in response to warm temperatures, cold acclimated plants lose freezing tolerance and resume growth and development. While considerable effort has been directed toward understanding the molecular and metabolic basis of cold acclimation, much less information is available about the regulation of deacclimation...
September 16, 2017: BMC Genomics
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