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https://www.readbyqxmd.com/read/28329435/face-shield-design-against-blast-induced-head-injuries
#1
Long Bin Tan, Kwong Ming Tse, Yuan Hong Tan, Mohamad Ali Bin Sapingi, Vincent Beng Chye Tan, Heow Pueh Lee
Blast-induced traumatic brain injury (TBI) has been on the rise in recent years due to the increasing use of improvised explosive devices (IEDs) in conflict zones. Our study investigates the response of a helmeted human head subjected to a blast of 1 atm peak overpressure, for cases with and without a standard polycarbonate (PC) face shield and for face shields comprising of composite PC and aerogel materials and with lateral edge extension. The novel introduction of aerogel into the laminate face shield is explored and its wave-structure interaction mechanics and performance in blast mitigation is analysed...
March 22, 2017: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/28328632/use-of-processed-nerve-allografts-to-repair-nerve-injuries-greater-than-25-mm-in-the-hand
#2
Brian Rinker, Jozef Zoldos, Renata V Weber, Jason Ko, Wesley Thayer, Jeffrey Greenberg, Fraser J Leversedge, Bauback Safa, Gregory Buncke
Processed nerve allografts (PNAs) have been demonstrated to have improved clinical results compared with hollow conduits for reconstruction of digital nerve gaps less than 25 mm; however, the use of PNAs for longer gaps warrants further clinical investigation. Long nerve gaps have been traditionally hard to study because of low incidence. The advent of the RANGER registry, a large, institutional review board-approved, active database for PNA (Avance Nerve Graft; AxoGen, Inc, Alachua, FL) has allowed evaluation of lower incidence subsets...
March 21, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28323898/perfluorocarbon-reduces-cell-damage-from-blast-injury-by-inhibiting-signal-paths-of-nf-%C3%AE%C2%BAb-mapk-and-bcl-2-bax-signaling-pathway-in-a549-cells
#3
Zhaorui Zhang, Zhixin Liang, Huaidong Li, Chunsun Li, Zhen Yang, Yanqin Li, Danyang She, Lu Cao, Wenjie Wang, Changlin Liu, Liangan Chen
BACKGROUND AND OBJECTIVE: Blast lung injury is a common type of blast injury and has very high mortality. Therefore, research to identify medical therapies for blast injury is important. Perfluorocarbon (PFC) is used to improve gas exchange in diseased lungs and has anti-inflammatory functions in vitro and in vivo. The aim of this study was to determine whether PFC reduces damage to A549 cells caused by blast injury and to elucidate its possible mechanisms of action. STUDY DESIGN AND METHODS: A549 alveolar epithelial cells exposed to blast waves were treated with and without PFC...
2017: PloS One
https://www.readbyqxmd.com/read/28322622/central-nervous-system-changes-induced-by-underbody-blast-induced-hyperacceleration-an-in-vivo-diffusion-tensor-imaging-and-magnetic-resonance-spectroscopy-study
#4
Shiyu Tang, Su Xu, William L Fourney, Ulrich H Leiste, Julie L Proctor, Gary Fiskum, Rao P Gullapalli
Blast-related traumatic brain injury (bTBI) resulting from improvised explosive devices is the hallmark injury of recent wars, and affects many returning veterans who experienced either direct or indirect exposure. Many of these veterans have long-term neurocognitive symptoms. However, there is very little evidence to show whether blast-induced acceleration alone, in the absence of secondary impacts, can cause mild TBI. In this study, we examine the effect of under-vehicle blast-induced hyperacceleration (uBIH) of ∼1700 g on the biochemical and microstrucutral changes in the brain using diffusion tensor imaging (DTI) and magnetic resonance spectroscopy (MRS)...
March 21, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28293522/a-case-report-of-the-first-nonburn-related-military-trauma-victim-treated-with-spray-skin-regenerative-therapy-in-combination-with-a-dermal-regenerate-template
#5
Ian L Valerio, Daniel A Hammer, Juan L Rendon, Kerry P Latham, Mark E Fleming
Massive soft tissue and skin loss secondary to war-related traumas are among the most frequently encountered challenges in the care of wounded warriors. This case report outlines the first military nonburn-related trauma patient treated by a combination of regenerative modalities. Our case employs spray skin technology to an established dermal regenerate matrix. Our patient, a 29-year-old active duty male, suffered a combat blast trauma in 2010 while deployed. The patient's treatment course was complicated by a severe necrotizing fasciitis infection requiring over 100 surgical procedures for disease control and reconstruction...
December 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28292391/endovascular-treatment-of-carotid-internal-jugular-venous-fistula-in-a-bomb-blast-victim
#6
Tariq Ashraf, Navedullah Khan, K M Yousaf, Maha Zainab Z. Yaqub
Carotid-internal jugular venous fistula is one of the rarest presentations among victims of bomb blast injuries. Treatment of such fistula is open surgery with high mortality and morbidity. Endovascular treatment with covered stent seems to have an optimal result with low complications. We present a case report of a bomb blast victim having carotid-jugular venous fistula with hemodynamic compromise. The patient was successfully managed with endovascular graft stent. There was an optimal result with no immediate and long-term complications...
February 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28291503/regenerative-and-antibacterial-properties-of-acellular-fish-skin-grafts-and-human-amnion-chorion-membrane-implications-for-tissue-preservation-in-combat-casualty-care
#7
Skuli Magnusson, Baldur Tumi Baldursson, Hilmar Kjartansson, Ottar Rolfsson, Gudmundur Fertram Sigurjonsson
BACKGROUND: Improvised explosive devices and new directed energy weapons are changing warfare injuries from penetrating wounds to large surface area thermal and blast injuries. Acellular fish skin is used for tissue repair and during manufacturing subjected to gentle processing compared to biologic materials derived from mammals. This is due to the absence of viral and prion disease transmission risk, preserving natural structure and composition of the fish skin graft. OBJECTIVES: The aim of this study was to assess properties of acellular fish skin relevant for severe battlefield injuries and to compare those properties with those of dehydrated human amnion/chorion membrane...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28291478/blast-wave-dynamics-at-the-cornea-as-a-function-of-eye-protection-form-and-fit
#8
Steven T Williams, Thomas H Harding, J Keegan Statz, John S Martin
A shock tube and anthropomorphic headforms were used to investigate eye protection form and fit using eyewear on the Authorized Protective Eyewear List in primary ocular blast trauma experiments. Time pressure recordings were obtained from highly linear pressure sensors mounted at the cornea of instrumented headforms of different sizes. A custom shock tube produced highly reliable shock waves and pressure recordings were collected as a function of shock wave orientation and protective eyewear. Eyewear protection coefficients were calculated as a function of a new metric of eyewear fit...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28291466/development-of-a-portable-tool-for-screening-neuromotor-sequelae-from-repetitive-low-level-blast-exposure
#9
Christopher K Rhea, Nikita A Kuznetsov, Scott E Ross, Benjamin Long, Jason T Jakiela, Jason M Bailie, Matthew A Yanagi, F Jay Haran, W Geoffrey Wright, Rebecca K Robins, Paul D Sargent, Joshua L Duckworth
Blast exposure is a prevalent cause of mild traumatic brain injury (mTBI) in military personnel in combat. However, it is more common for a service member to be exposed to a low-level blast (LLB) that does not result in a clinically diagnosable mTBI. Recent research suggests that repetitive LLB exposure can result in symptomology similar to symptoms observed after mTBI. This manuscript reports on the use of an Android-based smartphone application (AccWalker app) to capture changes in neuromotor functioning after blast exposure...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28291460/validation-of-laboratory-animal-and-surrogate-human-models-in-primary-blast-injury-studies
#10
Namas Chandra, Aravind Sundaramurthy, Raj K Gupta
Blast-induced neurotrauma has affected more than 300,000 service members. It is important to understand the effect of single and repeated shock-blast wave exposures on the neuropsychological behavior of soldiers, to offer them better protection, diagnostics, and treatment. Preclinical animal models and helmet design studies on human surrogate models have relied on the use of compression gas-driven shock tubes. Traditional shock tubes are so simple that if not carefully designed and operated, the test results can easily introduce detrimental artifacts clouding the conclusions...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28291459/clinical-and-magnetic-resonance-spectroscopic-imaging-findings-in-veterans-with-blast-mild-traumatic-brain-injury-and-post-traumatic-stress-disorder
#11
Anthony P Kontos, Anne C Van Cott, Jodilyn Roberts, Jullie W Pan, Monique B Kelly, Jamie McAllister-Deitrick, Hoby P Hetherington
OBJECTIVES: To compare magnetic resonance spectroscopic imaging (MRSI) findings from the hippocampal regions of military veterans with blast-related mild traumatic brain injury (blast mTBI) and post-traumatic stress disorder (PTSD) to those with PTSD only; and to examine the relationship of MRSI findings to cognitive and neuromotor impairment. METHODS: 35 military veterans-23 with blast mTBI and PTSD (blast mTBI/PTSD) and 12 with PTSD only participated in the study...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28291451/prehospital-blood-transfusion-during-aeromedical-evacuation-of-trauma-patients-in-israel-the-idf-csar-experience
#12
Jacob Chen, Avi Benov, Roy Nadler, Daniel N Darlington, Andrew P Cap, Ari M Lipsky, Elon Glassberg
BACKGROUND: Data regarding the effect of prehospital blood administration to trauma patients during short-to-moderate time evacuations is scarce. The Israel Air Force Airborne Combat Search and Rescue is the only organization that deals with aeromedical evacuation for both military and civilian casualties in Israel and the only one with the ability to give blood in the prehospital setting. METHODS: Data on packed red blood cells (PRBCs) administration in the evacuation missions from January 2003 to June 2010 were analyzed and actual transfusion practice was compared to clinical practice guidelines (CPGs)...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28289914/firecracker-eye-exposure-experimental-study-and-simulation
#13
Chiara Clemente, Luca Esposito, Domenico Speranza, Nicola Bonora
Understanding the mechanisms of traumatic ocular injury is helpful to make accurate diagnoses before the symptoms emerge and to develop specific eye protection. The comprehension of the dynamics of primary blast injury mechanisms is a challenging issue. The question is whether the pressure wave propagation and reflection alone could cause ocular damage. To date, there are dissenting opinions and no conclusive evidence thereupon. A previous numerical investigation of blast trauma highlighted the dynamic effect of pressure propagation and its amplification by the geometry of the bony orbit, inducing a resonance cavity effect and a standing wave hazardous for eye tissues...
March 13, 2017: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/28280662/avoiding-facial-incisions-with-midface-free-tissue-transfer
#14
Mark W Stalder, Michael Sosin, Leo J Urbinelli, James L Mayo, Amir H Dorafshar, Hugo St Hilaire, Daniel E Borsuk, Eduardo D Rodriguez
BACKGROUND: We have adopted an intraoral microsurgical anastomosis to the facial vessels to eliminate the need for any visible facial incisions. METHODS: Cadaveric dissection was used to demonstrate accessibility of the facial artery and vein through an intraoral approach. Additionally, 5 patients underwent free tissue transfer for reconstruction of major defects of the midface through an intraoral, transmucosal approach, obviating the need for visible skin incisions...
February 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28277589/medical-missions-in-the-middle-east-an-orthopaedic-surgeon-s-experience-of-a-series-of-lower-extremity-cases
#15
Aiman Rifai, Todd P Pierce, Kimona Issa, Yasmine Rifai, Bartlomiej Szczech
Orthopaedic trauma accounts for a great deal of disability worldwide. There are many impoverished nations affected by war wherein victims suffer blast injuries associated with mines, missiles, high-powered gunshots, and bombings. One way to address this is through international medical missions sponsored by industrialized nations. It is imperative that practitioners have a basic understanding of the type of injuries that may be encountered in these nations impacted by war and conflict. Therefore, we described a small number of various lower extremity injuries seen by one orthopaedic surgeon during his volunteer medical mission to Jordan...
March 9, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/28275059/differences-in-post-injury-auditory-system-pathophysiology-after-mild-blast-and-non-blast-acute-acoustic-trauma
#16
Nicholas Race, Jesyin Lai, Riyi Shi, Edward L Bartlett
Hearing difficulties are the most commonly reported disabilities among veterans. Blast exposures during explosive events likely play a role, given their propensity to directly damage both peripheral (PAS) and central (CAS) auditory system components. Post-blast PAS pathophysiology has been well-documented in both clinical case reports and laboratory investigations. In contrast, blast-induced CAS dysfunction remains under-studied, but has been hypothesized to contribute to an array of common veteran behavioral complaints including learning, memory, communication, and emotional regulation...
March 8, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28270259/assessment-of-the-knowledge-of-blast-injuries-management-among-physicians-working-in-tripoli-hospitals-libya
#17
Abdulhakim M Oun, Elmokhtar M Hadida, Charles Stewart
Introduction No study on hospital staff preparedness for managing blast injuries has been conducted in Libya. The internal conflict in Libya since 2011 and the difficulties faced by the hospitals has highlighted the need for such studies. Hypothesis Physicians working in Tripoli (capital city Libya) hospitals are inadequately prepared for the management of blast injuries. METHODS: A survey was conducted in all 13 hospitals in Tripoli between June 2014 and May 2015 by using interviews based on a questionnaire consisting of 29 questions covering physicians' education related to blast injury, hospital management of mass casualties, and aspects of hospital preparedness for such incidents...
March 8, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/28269777/what-is-the-relationship-of-traumatic-brain-injury-to-dementia
#18
Mario F Mendez
There is a long history linking traumatic brain injury (TBI) with the development of dementia. Despite significant reservations, such as recall bias or concluding causality for TBI, a summary of recent research points to several conclusions on the TBI-dementia relationship. 1) Increasing severity of a single moderate-to-severe TBI increases the risk of subsequent Alzheimer's disease (AD), the most common type of dementia. 2) Repetitive, often subconcussive, mild TBIs increases the risk for chronic traumatic encephalopathy (CTE), a degenerative neuropathology...
March 2, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28264063/acute-death-of-astrocytes-in-blast-exposed-rat-organotypic-hippocampal-slice-cultures
#19
Anna P Miller, Alok S Shah, Brandy V Aperi, Shekar N Kurpad, Brian D Stemper, Aleksandra Glavaski-Joksimovic
Blast traumatic brain injury (bTBI) affects civilians, soldiers, and veterans worldwide and presents significant health concerns. The mechanisms of neurodegeneration following bTBI remain elusive and current therapies are largely ineffective. It is important to better characterize blast-evoked cellular changes and underlying mechanisms in order to develop more effective therapies. In the present study, our group utilized rat organotypic hippocampal slice cultures (OHCs) as an in vitro system to model bTBI. OHCs were exposed to either 138 ± 22 kPa (low) or 273 ± 23 kPa (high) overpressures using an open-ended helium-driven shock tube, or were assigned to sham control group...
2017: PloS One
https://www.readbyqxmd.com/read/28243574/5-year-imaging-sequelae-of-concussive-blast-injury-and-relation-to-early-clinical-outcome
#20
Christine L Mac Donald, Jason Barber, Jalal Andre, Nicole Evans, Chris Panks, Samantha Sun, Kody Zalewski, R Elizabeth Sanders, Nancy Temkin
Current imaging diagnostic techniques are often insensitive to the underlying pathological changes following mild traumatic brain injury (TBI) or concussion so much so that the explicit definition of these uncomplicated mild brain injuries includes the absence of radiological findings. In the US military, this is complicated by the natural tendency of service members to down play symptoms for fear of removal from their unit particularly in combat making it challenging for clinicians to definitively diagnose and determine course of treatment...
2017: NeuroImage: Clinical
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