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Maze procedure

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https://www.readbyqxmd.com/read/29146879/2-cl-mgv-1-ameliorates-apoptosis-in-the-thalamus-and-hippocampus-and-cognitive-deficits-after-cortical-infarct-in-rats
#1
Yicong Chen, Leo Veenman, Sukhdev Singh, Fubing Ouyang, Jiahui Liang, Weixian Huang, Ilan Marek, Jinsheng Zeng, Moshe Gavish
BACKGROUND AND PURPOSE: Focal cortical infarction causes neuronal apoptosis in the ipsilateral nonischemic thalamus and hippocampus, which is potentially associated with poststroke cognitive deficits. TSPO (translocator protein) is critical in regulating mitochondrial apoptosis pathways. We examined the effects of the novel TSPO ligand 2-(2-chlorophenyl)quinazolin-4-yl dimethylcarbamate (2-Cl-MGV-1) on poststroke cognitive deficits, neuronal mitochondrial apoptosis, and secondary damage in the ipsilateral thalamus and hippocampus after cortical infarction...
November 16, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29138143/minimally-invasive-stand-alone-cox-maze-procedure-for-persistent-and-long-standing-persistent-atrial-fibrillation-perioperative-safety-and-5-year-outcomes
#2
Niv Ad, Sari D Holmes, Ted Friehling
BACKGROUND: Rhythm control is challenging in patients with extended atrial fibrillation (AF) duration and persistent/long-standing persistent AF. Among surgical approaches to treat AF, the Cox maze procedure performed using alternative energy sources remains superior to other beating heart techniques. We examined permanence of safety and success for the on-pump, minimally invasive, stand-alone Cox maze procedure 5 years after surgery. METHODS AND RESULTS: Stand-alone, right 5 cm minithoracotomy, Cox maze III/IV procedure for nonparoxysmal AF was conducted in 133 patients (mean follow-up=65±34 months)...
November 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29102211/cox-maze-iv-procedure-is-effective-but-is-it-for-everybody
#3
EDITORIAL
G Hossein Almassi
No abstract text is available yet for this article.
October 5, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29098009/maternal-sevoflurane-exposure-causes-abnormal-development-of-fetal-prefrontal-cortex-and-induces-cognitive-dysfunction-in-offspring
#4
Ruixue Song, Xiaomin Ling, Mengyuan Peng, Zhanggang Xue, Jing Cang, Fang Fang
Maternal sevoflurane exposure during pregnancy is associated with increased risk for behavioral deficits in offspring. Several studies indicated that neurogenesis abnormality may be responsible for the sevoflurane-induced neurotoxicity, but the concrete impact of sevoflurane on fetal brain development remains poorly understood. We aimed to investigate whether maternal sevoflurane exposure caused learning and memory impairment in offspring through inducing abnormal development of the fetal prefrontal cortex (PFC)...
2017: Stem Cells International
https://www.readbyqxmd.com/read/29080676/amygdaloid-involvement-in-the-defensive-behavior-of-mice-exposed-to-the-open-elevated-plus-maze
#5
Tatiani Sorregotti, Ana Cláudia Cipriano, Fábio Cardoso Cruz, Diego Cardozo Mascarenhas, Robert John Rodgers, Ricardo Luiz Nunes-de-Souza
Previous studies have shown that the exposure to an open elevated plus maze (oEPM, an EPM with all four open arms) elicits fear/anxiety-related responses in laboratory rodents. However, very little is known about the underlying neural substrates of these defensive behaviors. Accordingly, the present study investigated the effects of chemical inactivation of the amygdala [through local injection of cobalt chloride (CoCl2: a nonspecific synaptic blocker)] on the behavior of oEPM-exposed mice. In a second experiment, the pattern of activation of the basolateral (BLA) and central (CeA) nuclei of the amygdala was assessed through quantification of Fos protein expression in mice subjected to one of several behavioral manipulations...
October 31, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/29056264/performance-of-the-cox-maze-iv-procedure-is-associated-with-improved-long-term-survival-in-patients-with-atrial-fibrillation-undergoing-cardiac-surgery
#6
Farah N Musharbash, Matthew R Schill, Laurie A Sinn, Richard B Schuessler, Hersh S Maniar, Marc R Moon, Spencer J Melby, Ralph J Damiano
OBJECTIVE: Atrial fibrillation (AF) is associated with an increased mortality risk. The Cox-maze IV procedure (CM4) performed concomitantly with other cardiac procedures has been shown to be effective for restoring sinus rhythm. However, few data have been published on the late survival of patients undergoing a concomitant CM4. METHODS: Patients undergoing cardiac surgery were retrospectively reviewed from 2001 to 2016 (n = 10,859). Patients were stratified into 3 groups: patients with a history of AF receiving a concomitant CM4 (CM4; n = 438), patients with a history of AF unaddressed during surgery (Untreated AF; n = 1510), and patients without AF history (No AF; n = 8911)...
September 27, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29018340/impaired-spatial-memory-and-enhanced-habit-memory-in-a-rat-model-of-post-traumatic-stress-disorder
#7
Jarid Goodman, Christa K McIntyre
High levels of emotional arousal can impair spatial memory mediated by the hippocampus, and enhance stimulus-response (S-R) habit memory mediated by the dorsolateral striatum (DLS). The present study was conducted to determine whether these memory systems may be similarly affected in an animal model of post-traumatic stress disorder (PTSD). Sprague-Dawley rats were subjected to a "single-prolonged stress" (SPS) procedure and 1 week later received training in one of two distinct versions of the plus-maze: a hippocampus-dependent place learning task or a DLS-dependent response learning task...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28986731/successful-management-of-prolonged-venovenous-extracorporeal-membrane-oxygenation-in-an-octogenarian
#8
Masami Takagaki, Hiroki Yamaguchi, Shinichi Mitsuyama, Tasuku Kadowaki, Takeshi Ando
Venovenous extracorporeal membrane oxygenation is now an established treatment for acute respiratory distress syndrome. However, this treatment remains rare in octogenarians and is associated with poor outcomes. An 81-year-old man with a history of chronic obstructive pulmonary disease and heavy smoking underwent mitral and tricuspid valve repair and the Maze procedure for mitral and tricuspid regurgitation and paroxysmal atrial fibrillation. Although he was extubated the following day, his postoperative course was complicated with pneumonia followed by acute respiratory distress syndrome...
October 6, 2017: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/28982596/subsequent-maternal-separation-exacerbates-neurobehavioral-abnormalities-in-rats-neonatally-exposed-to-sevoflurane-anesthesia
#9
Jiaojiao Yang, Lingsha Ju, Min Jia, Hui Zhang, Xiaoru Sun, Muhuo Ji, Jianjun Yang, Anatoly E Martynyuk
Several recent studies suggest that in the human population, a routine, short anesthetic in otherwise healthy infants is void of neurodevelopmental insult. On the other hand, many human retrospective epidemiological studies report evidence of cognitive abnormalities in children after testing those who had different anesthesia-requiring procedures in early childhood. We tested in a rat model whether post-anesthesia stressful environmental factors can contribute to developmental abnormalities that were initiated by a relatively short exposure to sevoflurane, the most widely used anesthetic in pediatric anesthesia, whose polyvalent actions include enhancement of gamma-aminobutyric acid type A receptor (GABAAR) activity...
November 20, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28981441/assessment-of-the-antioxidant-thrombolytic-analgesic-anti-inflammatory-antidepressant-and-anxiolytic-activities-of-leaf-extracts-and-fractions-of-tetracera-sarmentosa-l-vahl
#10
Mir Muhammad Nasir Uddin, Mohammad Shah Hafez Kabir, Mahmud Hasan, Zobaer Al Mahmud, N M Mahmudul Alam Bhuiya, Farhan Ahmed, Md Rakibul Hasan, Mohammad Tanvir Hosen, Mohammad Shahin Alam
BACKGROUND: The plant under investigation (Tetracera sarmentosa) is a dicotyledonous flowering plant and belongs to the family Dilleniaceae. The goal of our investigation was to determine whether the leaf extracts of this plant held any significant medicinal properties. METHODS: Leaves of T. sarmentosa were extracted with pure ethanol (EETS) and methanol (METS), and then methanol extract fractioned with n-hexane (NHFMETS) and chloroform (CHFMETS). The extracts and fractions were tested for antioxidant activity, which was measured by using qualitative and quantitative procedures...
October 5, 2017: Journal of Basic and Clinical Physiology and Pharmacology
https://www.readbyqxmd.com/read/28977803/stimulation-of-anxiety-like-behavior-via-erk-pathway-by-competitive-serotonin-receptors-2a-and-1a-in-post-traumatic-stress-disordered-mice
#11
Mingjun Xiang, Yuting Jiang, Zhiying Hu, Yang Yang, Benson O A Botchway, Marong Fang
BACKGROUND/AIMS: Serotonin 5HT2A and 5HT1A receptors (5HT2AR, 5HT1AR) have the closest connection to anxiety-like behavior in post-traumatic stress disorder (PTSD). However, the underlying mechanism remains unclear. In this study, we explored the connection between 5HT2A and 5HT1A receptors and anxiety-like behavior. METHODS: In the PTSD animal model, mice were exposed to conditioned fear stress coupled with single-prolonged stress (CF+SPS). Post stress infliction and behavioral tests, of which include open field, freezing behavior and elevated plus maze tests were carried out to examine establishment of the proposed model...
October 6, 2017: Neuro-Signals
https://www.readbyqxmd.com/read/28974318/how-amazing-is-a-maze-procedure-in-the-obstructive-hypertrophic-cardiomyopathy-population
#12
EDITORIAL
Yuichi J Shimada, Shepard D Weiner, Hiroo Takayama
No abstract text is available yet for this article.
September 11, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28965725/a-prospective-randomized-trial-of-the-cut-and-sew-maze-procedure-in-patients-undergoing-surgery-for-rheumatic-mitral-valve-disease
#13
Huishan Wang, Jinsong Han, Zengwei Wang, Zongtao Yin, Zhigang Liu, Yan Jin, Hongguang Han
OBJECTIVE: To evaluate the safety and efficacy of the addition of the cut-and-sew Maze III procedure (CSM) for mitral valve replacement (MVR) in patients with atrial fibrillation (AF) associated with rheumatic mitral valve disease (RMVD). METHODS: A total of 130 patients with persistent or long-standing persistent AF associated with RMVD were assigned at random to either the CSM plus MVR (Maze III) group or MVR alone (non-Maze) group. The primary endpoint was a composite of freedom from stroke and death at 1 year...
September 5, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28954974/a-case-of-cerebral-embolism-with-a-large-thrombus-in-the-left-atrium-and-a-recurrence-of-thrombus-in-the-left-atrium-after-the-maze-procedure
#14
Masafumi Arakawa, Takashi Shimoyama, Noriko Matsumoto, Satoshi Suda, Jiro Kurita, Kazumi Kimura
A 67-year-old woman developed weakness of the entire left side of the body and disturbance of consciousness, and was admitted to our hospital. She had atrial fibrillation (AF) on arrival at the hospital. Diffusion weighted magnetic resonance imaging showed high intensity area in the right basal ganglia, and magnetic resonance angiography showed occlusion of the right internal carotid artery (ICA). Thrombolytic therapy with intravenous tissue plasminogen activator (IV tPA) was administered 225 minutes after onset, and endovascular procedure also performed...
October 27, 2017: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/28947201/concomitant-ablation-for-atrial-fibrillation-during-septal-myectomy-in-patients-with-hypertrophic-obstructive-cardiomyopathy
#15
Alexander V Bogachev-Prokophiev, Alexander V Afanasyev, Sergei I Zheleznev, Alexei N Pivkin, Michael S Fomenko, Ravil M Sharifulin, Alexander M Karaskov
OBJECTIVE: The appearance of atrial fibrillation is associated with significant clinical deterioration in patients with obstructive hypertrophic cardiomyopathy; therefore, maintenance of sinus rhythm is desirable. Guidelines and most articles have reported the results of catheter ablation and pharmacologic atrial fibrillation treatment; nevertheless, data regarding concomitant procedures during septal myectomy are limited. The aim of this study was to assess the outcomes of concomitant atrial fibrillation treatment in patients with obstructive hypertrophic cardiomyopathy...
September 1, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28944261/delayed-matching-to-place-task-in-a-dry-maze-to-measure-spatial-working-memory-in-mice
#16
Xi Feng, Karen Krukowski, Timothy Jopson, Susanna Rosi
The delayed-matching-to-place (DMP) dry maze test is a variant of DMP water maze (Steele and Morris, 1999; Faizi et al., 2012) which measures spatial working/episodic-like learning and memory that depends on both hippocampal and cortical functions (Wang and Morris, 2010; Euston et al., 2012). Using this test we can detect normal aging related spatial working memory decline, as well as trauma induced working memory deficits. Furthermore, we recently reported that fractionated whole brain irradiation does not affect working memory in mice (Feng et al...
July 5, 2017: Bio-protocol
https://www.readbyqxmd.com/read/28944180/surgical-management-of-atrial-fibrillation-at-the-time-of-septal-myectomy
#17
Eduard Quintana, James L Cox
Atrial fibrillation (AF) may appear during the natural clinical course of hypertrophic cardiomyopathy (HCM). It is regarded as a complication of HCM and is a marker of advanced disease. AF is more likely to occur in untreated, obstructive HCM. Unfortunately, this represents a turning point that puts patients at increased risk of further disability, stroke and death. The presence of obstruction is an indication to proceed with septal myectomy to improve or resolve symptoms by ameliorating diastolic dysfunction...
July 2017: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28916640/clinical-profile-and-consequences-of-atrial-fibrillation-in-hypertrophic-cardiomyopathy
#18
Ethan J Rowin, Anais Hausvater, Mark S Link, Patrick Abt, William Gionfriddo, Wendy Wang, Hassan Rastegar, N A Mark Estes, Martin S Maron, Barry J Maron
Background -Atrial fibrillation (AF), the most common sustained arrhythmia in hypertrophic cardiomyopathy (HCM), is capable of producing symptoms that impact quality of life and is associated with risk for embolic stroke. However, the influence of AF on clinical course and outcome in HCM remains incompletely resolved. Methods -Records were accessed of 1558 consecutive patients followed at the Tufts Medical Center Hypertrophic Cardiomyopathy Institute for 4.8 ± 3.4 years, from 2004 to 2014. Results -Of the 1558 HCM patients, 304 (20%) had episodes of AF, of which 226 (74%) were confined to symptomatic paroxysmal AF (PAF; average 5 ± 5; range 1 to > 20), while 78 (26%) developed permanent AF, preceded by 7 ± 6 PAF episodes...
September 15, 2017: Circulation
https://www.readbyqxmd.com/read/28914428/anhydroecgonine-methyl-ester-aeme-a-product-of-cocaine-pyrolysis-impairs-spatial-working-memory-and-induces-striatal-oxidative-stress-in-rats
#19
Elisa Fraga Gomes, Ingryd Fortes Souza Lipaus, Cleciane Waldetário Martins, Andrezza Menezes Araújo, Josidéia Barreto Mendonça, Fabrício Souza Pelição, Evandro Carlos Lebarch, Lívia Carla de Melo Rodrigues, Ester Miyuki Nakamura-Palacios
When burning crack cocaine, the pyrolysis of cocaine generates anhydroecgonine methyl ester (AEME). AEME has been shown to be highly neurotoxic but its effects on cognitive function and oxidative stress are still unknown. Thus, this study investigated the effects of AEME on spatial working memory and on parameters of oxidative stress in the prefrontal cortex, hippocampus, and striatum. First, 18 well-trained rats in 8-arm radial maze (8-RM) procedures received acute intracerebroventricular (icv) administration of AEME at doses of 10, 32, or 100 μg or saline (SAL) in a counterbalanced order and were tested 5 min later in 1-h delayed tasks in the 8-RM...
September 15, 2017: Neurotoxicity Research
https://www.readbyqxmd.com/read/28911267/the-behavioral-and-molecular-evaluation-of-effects-of-social-instability-stress-as-a-model-of-stress-related-disorders-in-adult-female-rats
#20
Marta Maria Nowacka-Chmielewska, Daniela Kasprowska-Liśkiewicz, Jarosław Jerzy Barski, Ewa Obuchowicz, Andrzej Małecki
The study aimed to test the hypotheses that chronic social instability stress (CSIS) alters behavioral and physiological parameters and expression of selected genes important for stress response and social behaviors. Adult female Sprague-Dawley rats were subjected to the 4-week CSIS procedure, which involves unpredictable rotation between phases of isolation and overcrowding. Behavioral analyses (Experiment 1) were performed on the same rats before and after CSIS (n = 16) and physiological and biochemical measurements (Experiment 2) were made on further control (CON; n = 7) and stressed groups (CSIS; n = 8)...
September 15, 2017: Stress: the International Journal on the Biology of Stress
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