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https://www.readbyqxmd.com/read/29346633/intraoperative-epicardial-focal-pulmonary-venous-electrocardiography-in-patients-with-atrial-fibrillation
#1
Grzegorz Suwalski, Robert Emery, Jakub Mróz, Kamil Kaczejko, Leszek Gryszko, Andrzej Cwetsch, Andrzej Skrobowski
OBJECTIVES: In patients referred to off-pump coronary artery bypass grafting, pulmonary vein isolation (PVI) may be used for those with persistent atrial fibrillation (AF), an alternative to the Maze procedure. However, the success rate of PVI in persistent AF is limited. The study assesses the prognostic value of focal epicardial electrocardiography of the pulmonary veins (PVs) for surgical ablation results. METHODS: We mapped 140 PV in 35 cases undergoing off-pump coronary artery bypass grafting...
January 15, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29346276/comparison-of-the-response-of-male-balb-c-and-c57bl-6-mice-in-behavioral-tasks-to-evaluate-cognitive-function
#2
Yenela Garcia, Nashelly Esquivel
To evaluate several cognitive parameters during the execution of behavioral tasks assessing cognitive function in laboratory animals, the parameters are reported within a range. This situation entails that each laboratory must establish the conditions under which the behavioral task to evaluate the cognitive function can be carried out. C57BL/6 and BALB/c inbred strains are used more often in behavioral studies relating to anxiety, stress, fear and cognitive function. The aim of this work was to compare the behavioral response of mice of the strains BALB/c and C57BL/6 to evaluate memory and learning as cognitive functions...
January 18, 2018: Behavioral Sciences
https://www.readbyqxmd.com/read/29327638/hybrid-and-surgical-procedures-for-the-treatment-of-persistent-and-longstanding-persistent-atrial-fibrillation
#3
Jose M Sanchez, Ghannam Al-Dosari, Sherman Chu, Ramin Beygui, Tobias Deuse, Nitish Badhwar, Randall J Lee
Atrial fibrillation (AF) is the most common cardiac arrhythmia. The incidence of AF increases with age and is associated with increased stroke, heart failure and mortality. Persistent and long standing persistent AF is difficult to treat and often refractory to medical therapy and catheter ablation. Areas covered: This article reviews the historical development of the surgical Cox-MAZE procedure and current hybrid and minimally invasive surgical approaches for the treatment of persistent and long standing persistent AF...
January 12, 2018: Expert Review of Cardiovascular Therapy
https://www.readbyqxmd.com/read/29312724/long-term-results-of-radiofrequency-maze-procedure-for-persistent-atrial-fibrillation-with-concomitant-mitral-surgery
#4
Chia-Chen Wu, Jen-Ping Chang, Mien-Cheng Chen, Cheng-I Cheng, Wen-Jung Chung
Background: The radiofrequency (RF) maze procedure can effectively restore sinus rhythm in most patients with persistent atrial fibrillation (AF) and mitral disease. However, long-term results and predictors for late AF recurrence are still under investigation. Methods: From December 1995 to November 2011, 207 consecutive patients with persistent AF and mitral disease underwent RF maze procedure and concomitant mitral surgery. The mean age was 54±12.4 year-old...
December 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29287786/leptin-treatment-prevents-long-term-abnormalities-in-cognition-seizure-threshold-hippocampal-mossy-fiber-sprouting-and-znt3-cb-d28k-expression-in-a-rat-developmental-twist-seizure-model
#5
Hong Ni, Su-Hong Chen, Li-Li Li, Mei-Fang Jin
The mechanism of linking neonatal seizures with long-term brain damage is unclear, and there is no effective drug to block this long-term pathological process. Recently, the fat-derived hormone leptin has been appreciated for its neuroprotective function in neurodegenerative processes, although less is known about the effects of leptin on neonatal seizure-induced brain damage. Here, we developed a "twist" seizure model by coupling pilocarpine-induced neonatal status epilepticus (SE) with later exposure to penicillin to test whether leptin treatment immediately after neonatal SE would exert neuroprotective effects on cognition, seizure threshold and hippocampal mossy fiber sprouting, as well if leptin had any influence on the expression of zinc transporter 3 (ZnT3) and calcium homeostasis-related CB-D28k in the hippocampus...
December 26, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/29276917/-the-integrated-approach-to-improving-efficiency-and-safety-of-anticoagulation-therapy-in-patients-with-prosthetic-mitral-valve
#6
E V Gorbunova, R R Salakhov, Y N Odarenko, S E Mamchur
AIM: To assess advantages of integrated approach to improvement of efficiency and safety of warfarin therapy after heart valve replacement. MATERIALS AND METHODS: We included in this study 118 patients who had undergone simultaneous mitral valve replacement and maze procedure. Group 1 patients (n=37) underwent just sinus rhythm restoration, group 2 patients (n=54) underwent sinus rhythm restoration and participated in a patient education program, group 3 patients (n=27) underwent sinus rhythm restoration, participated in a patient education program, and were subjected to pharmacogenetic testing for warfarin sensitivity...
November 2017: Kardiologiia
https://www.readbyqxmd.com/read/29274913/oral-anticoagulation-may-not-be-necessary-for-patients-discharged-in-sinus-rhythm-after-the-cox-maze-iv-procedure
#7
Takashi Murashita, J Scott Rankin, Lawrence M Wei, Harold G Roberts, Mohamad A Alkhouli, Vinay Badhwar
OBJECTIVES: Oral anticoagulants have inherent risks. In the absence of clear evidence, anticoagulant use after surgical ablation for atrial fibrillation remains variable. This study examined patient outcomes with and without oral anticoagulants after successful surgical ablation. METHODS: From October 2011 to April 2016, 239 consecutive patients underwent biatrial Cox Maze IV operations for persistent atrial fibrillation. All patients received endocardial left atrial appendage obliteration...
December 6, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29250276/comparison-of-the-efficancy-and-complication-rates-of-the-hybrid-maze-complete-cox-maze-and-catheter-ablation-in-the-treatment-of-atrial-fibrillation
#8
Ivo K Genev, Lindsey A Tompkins, Manorama M Khare, Farhad Farokhi
Introduction: Atrial fibrillation is the most common cardiac arrhythmia in the United States. It has been associated with a reduction in patient quality of life and more serious complications such as stroke and heart failure. The aim of this study was to compare the efficacy of commonly performed invasive procedures in keeping patients in normal sinus rhythm. Methods and Results: A retrospective chart review was performed on all patients who underwent primary radiofrequency catheter ablation, the complete Cox-maze, or the hybrid maze at OSF Saint Anthony Medical Center between January 2010 and December 2013 (n=140)...
February 2017: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/29250237/resolution-of-av-block-after-ablation-for-atrial-fibrillation
#9
Matthew Glassy, Nayereh Pezeshkian, Yingbo Yang, Uma N Srivatsa
We report a case with complete atrioventricular block (AVB) present both during sinus rhythm and with atrial fibrillation (AF). He had declined pacemaker placement and opted for ablation for the symptomatic AF. He underwent staged hybrid approach with video-assisted thoracoscopic surgical maze (VATS) followed by endocardial ablation. VATS included ganglionic plexi cauterization. One month after the endocardial procedure, he had complete resolution of AF and AVB and remains so at 18 months follow up. We discuss possible abolition of vagal input for this improvement in AV conduction...
August 2017: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/29248960/predictors-of-the-need-for-pacemaker-implantation-after-the-cox-maze-iv-procedure-for-atrial-fibrillation
#10
Naoki Masaki, Shunsuke Kawamoto, Naotaka Motoyoshi, Osamu Adachi, Kiichiro Kumagai, Satoshi Kawatsu, Yukihiro Hayatsu, Shintaro Katahira, Katsuhiro Hosoyama, Masatoshi Akiyama, Yoshikatsu Saiki
PURPOSE: The Cox maze IV (CMIV) procedure is being used increasingly frequently for surgical ablation of atrial fibrillation (AF). This study aimed to identify the risk factors of the need for postoperative pacemaker implantation (PMI) after CMIV. METHODS: Preoperative, intraoperative, and postoperative data were retrospectively collected from 67 consecutive patients who underwent CMIV at our institution; 7 (10.4%) required PMI (as a treatment of brady AF or sick sinus syndrome)...
December 16, 2017: Surgery Today
https://www.readbyqxmd.com/read/29246544/long-term-outcome-following-concomitant-mitral-valve-surgery-and-cox-maze-procedure-for-atrial-fibrillation
#11
Niv Ad, Sari D Holmes, Paul S Massimiano, Anthony J Rongione, Lisa M Fornaresio
OBJECTIVE: Atrial fibrillation (AF) is associated with increased early and long-term morbidity/mortality following valve surgery. This study examined long-term influence of concomitant full Cox maze (CM) and mitral valve procedures on freedom from atrial arrhythmia and stroke. METHODS: This sample comprised patients who underwent CM with a mitral valve procedure (N = 473). Data on rhythm, medication status, and clinical events captured according to Heart Rhythm Society guidelines at 6, 9, 12, 18, and 24 months and yearly thereafter up to 7 years...
November 14, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29240895/surgical-ablation-for-atrial-fibrillation-in-mitral-valve-disease-impact-of-the-maze-procedure-authors-response
#12
Louise Bagge, Carina Blomström-Lundqvist
No abstract text is available yet for this article.
December 11, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29240882/surgical-ablation-for-atrial-fibrillation-in-mitral-valve-disease-impact-of-the-maze-procedure
#13
Ovidio A Garcia-Villarreal
No abstract text is available yet for this article.
December 11, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29240293/transvenous-pacemaker-implantation-after-the-bidirectional-glenn-operation-for-patients-with-complex-congenital-disease
#14
Danielle E Harake, Kevin M Shannon, Jamil A Aboulhosn, Jeremy P Moore
INTRODUCTION: The bidirectional Glenn operation for congenital heart disease produces anatomical constraints to conventional transvenous pacemaker implantation. An iliac approach, although not previously described in this population, is potentially a preferable alternative to a thoracotomy for epicardial pacing. METHODS AND RESULTS: A single-center retrospective review was performed for all patients that underwent transvenous pacemaker implantation following the bidirectional Glenn operation with partial biventricular repair...
December 14, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29237374/maze-antitoxin-of-toxin-antitoxin-system-and-fbpa-as-reliable-targets-to-eradication-of-neisseria-meningitidis
#15
Abbas Maleki, Sobhan Ghafourian, Iraj Pakzad, Behzad Badakhsh, Nourkhoda Sadeghifard
BACKGROUND: Neisseria meningitidis is ‎considered as a dangerous pathogen ‎threaten human health. Now a day, the new drug target is focused. Toxin antitoxin (TA) system recently identified as an antimicrobial drug target. Also, in N. meningitidis iron-uptake system could be an interesting target for drug discovery. METHODS: Therefore, in this study fbpA and mazE genes were chosen as new antimicrobial targets and treated with antisense peptide nucleic ‎acid (PNA)...
December 12, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/29214653/administrative-billing-codes-accurately-identified-occurrence-of-electrical-cardioversion-and-ablation-maze-procedures-in-a-prospective-cohort-study-of-atrial-fibrillation-patients
#16
Alexa N Ehlert, Susan R Heckbert, Kerri L Wiggins, Evan L Thacker
BACKGROUND: Administrative billing codes for electrical cardioversion and ablation/maze procedures may be useful for atrial fibrillation (AF) research if the codes are accurate relative to medical record documentation. HYPOTHESIS: Administrative billing codes accurately identify occurrence of electrical cardioversion and ablation/maze procedures in AF patients. METHODS: We studied adults ages 30 to 84 who experienced new-onset AF between October 2001 and December 2004 in Group Health Cooperative (acquired by Kaiser Permanente in 2017), an integrated healthcare system in Washington state and northern Idaho...
December 6, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/29165033/a-comparison-of-various-methods-of-blood-sampling-in-mice-and-rats-effects-on-animal-welfare
#17
V S Harikrishnan, Axel K Hansen, Klas Sp Abelson, Dorte B Sørensen
This study was conducted to investigate the effects of blood sampling on animal welfare in a total of 60 NTac:SD rats and 72 C57BL/6NTac mice of both sexes. Blood was sampled either by sublingual vein puncture, tail vein puncture or by retrobulbar plexus/sinus puncture under light isoflurane anaesthesia and, additionally, by facial vein puncture in mice. Non-punctured animals as well as isoflurane-anaesthetised animals were used as controls. Pre- and post-puncture sucrose intake (1.5% w/w) was measured in rats, and nest building scores were studied in mice for 24 h post-puncture...
January 1, 2017: Laboratory Animals
https://www.readbyqxmd.com/read/29146879/2-cl-mgv-1-ameliorates-apoptosis-in-the-thalamus-and-hippocampus-and-cognitive-deficits-after-cortical-infarct-in-rats
#18
Yicong Chen, Leo Veenman, Sukhdev Singh, Fubing Ouyang, Jiahui Liang, Weixian Huang, Ilan Marek, Jinsheng Zeng, Moshe Gavish
BACKGROUND AND PURPOSE: Focal cortical infarction causes neuronal apoptosis in the ipsilateral nonischemic thalamus and hippocampus, which is potentially associated with poststroke cognitive deficits. TSPO (translocator protein) is critical in regulating mitochondrial apoptosis pathways. We examined the effects of the novel TSPO ligand 2-(2-chlorophenyl) quinazolin-4-yl dimethylcarbamate (2-Cl-MGV-1) on poststroke cognitive deficits, neuronal mitochondrial apoptosis, and secondary damage in the ipsilateral thalamus and hippocampus after cortical infarction...
December 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29138143/minimally-invasive-stand-alone-cox-maze-procedure-for-persistent-and-long-standing-persistent-atrial-fibrillation-perioperative-safety-and-5-year-outcomes
#19
Niv Ad, Sari D Holmes, Ted Friehling
BACKGROUND: Rhythm control is challenging in patients with extended atrial fibrillation (AF) duration and persistent/long-standing persistent AF. Among surgical approaches to treat AF, the Cox maze procedure performed using alternative energy sources remains superior to other beating heart techniques. We examined permanence of safety and success for the on-pump, minimally invasive, stand-alone Cox maze procedure 5 years after surgery. METHODS AND RESULTS: Stand-alone, right 5 cm minithoracotomy, Cox maze III/IV procedure for nonparoxysmal AF was conducted in 133 patients (mean follow-up=65±34 months)...
November 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29102211/cox-maze-iv-procedure-is-effective-but-is-it-for-everybody
#20
EDITORIAL
G Hossein Almassi
No abstract text is available yet for this article.
October 5, 2017: Journal of Thoracic and Cardiovascular Surgery
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