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cardiac sarcoidosis

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https://www.readbyqxmd.com/read/29784492/electrocardiogram-and-imaging-an-integrated-approach-to-arrhythmogenic-cardiomyopathies
#1
REVIEW
Ketty Savino, Giuseppe Bagliani, Federico Crusco, Margherita Padeletti, Massimo Lombardi
Cardiovascular imaging has radically changed the management of patients with arrhythmogenic cardiomyopathies. This article focuses on the role of echocardiography and MRI in the diagnosis of these structural diseases. Cardiomyopathies with hypertrophic pattern (hypertrophic cardiomyopathy, restrictive cardiomyopathies, amyloidosis, Anderson-Fabry disease, and sarcoidosis), cardiomyopathies with dilated pattern, inflammatory cardiac diseases, and right ventricular arrhythmogenic cardiomyopathy are analyzed. Finally, anatomic predictors of arrhythmias and sudden cardiac death are discussed...
June 2018: Cardiac Electrophysiology Clinics
https://www.readbyqxmd.com/read/29721764/18-fdg-pet-in-a-patient-cohort-suspected-for-cardiac-sarcoidosis-right-ventricular-uptake-is-associated-with-pathological-uptake-in-mediastinal-lymph-nodes
#2
Heikki Tuominen, Atte Haarala, Antti Tikkakoski, Mika Kähönen, Kjell Nikus, Kalle Sipilä
INTRODUCTION: In up to 65% of cardiac sarcoidosis patients, the disease is confined to the heart. Diagnosing isolated cardiac sarcoidosis is challenging due to the low sensitivity of endomyocardial biopsy. If cardiac sarcoidosis is part of biopsy-confirmed systemic sarcoidosis, the diagnosis can be based on cardiac imaging studies. We compared the imaging features of patients with isolated cardiac FDG uptake on positron emission tomography with those who had findings indicative of systemic sarcoidosis...
May 2, 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29681578/spontaneous-reduction-in-abnormal-myocardial-uptake-of-fluorine-18-fluorodeoxygluose-in-a-patient-with-cardiac-sarcoidosis
#3
Fumio Terasaki, Shu-Ichi Fujita, Yumiko Kanzaki, Yoshinobu Hirose, Nobukazu Ishizaka
Fluorine-18 fluorodeoxygluose (18 F-FDG) positron emission tomography (PET) is a useful tool for evaluating disease activity in sarcoidosis including cardiac involvement. A 67-year-old patient who developed atrioventricular block requiring permanent pacemaker implantation was diagnosed with cardiac sarcoidosis. The patient did not undergo steroid or immunosuppressive therapy but underwent serial 18 F-FDG PET examination, which showed spontaneous reduction in the myocardial FDG uptake, indicating the remission of immune-inflammatory activity...
April 20, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29628471/a-case-of-a-cardiac-resynchronization-therapy-defibrillator-exhibiting-a-lower-and-alternately-variable-basic-rate
#4
Keigo Iwazaki, Toshiya Kojima, Takahide Murasawa, Jun Yokota, Hikaru Tanimoto, Jun Matsuda, Nobuaki Fukuma, Takumi Matsubara, Yu Shimizu, Gaku Oguri, Eriko Hasumi, Hitoshi Kubo, Kyungho Chang, Katsuhito Fujiu, Issei Komuro
A cardiac resynchronization therapy defibrillator (CRT-D) (Medtronic Inc. Protecta XT) was implanted in a 67-year-old man who had cardiac sarcoidosis with extremely low cardiac function. He had ventricular tachycardia which was controlled by catheter ablation, medication and pacing. The programmed mode was DDI, lower rate was 90 beats/minute, paced AV delay was 150 ms, and the noncompetitive atrial pacing (NCAP) function was programmed as 300 ms.After his admission for pneumonia and heart failure, we changed his DDI mode to a DDD mode because he had atrial tachycardia, which led to inadequate bi-ventricular pacing...
April 6, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29619923/clinical-presentation-management-and-prognosis-of-patients-with-cardiac-sarcoidosis
#5
Muzhda Ghanizada, Kasper Rossing, Henning Bundgaard, Finn Gustafsson
INTRODUCTION: The course and prognosis of cardiac sarcoidosis (CS) are sparsely described. The purpose of this study was to assess the clinical presentation, treatment response and prognosis for patients with CS. METHODS: This was a single-centre retrospective study of patients with CS from 2006 to 2016. A total of 197 patients with a sarcoidosis diagnosis were screened, and 17 patients (mean age 46.9 years, 59% men) were diagnosed with CS based on Japanese Ministry of Health and Welfare criteria; 53% were diagnosed by a positive MRI, 29% by endomyocardial biopsy...
April 2018: Danish Medical Journal
https://www.readbyqxmd.com/read/29613987/focal-myocardial-damage-in-cardiac-sarcoidosis-characterized-by-strain-analysis-on-magnetic-resonance-tagged-imaging-in-comparison-with-fluorodeoxyglucose-positron-emission-tomography-accumulation-and-magnetic-resonance-late-gadolinium-enhancement
#6
Yoshiaki Watanabe, Tatsuya Nishii, Shinsuke Shimoyama, Tatsuro Ito, Shumpei Mori, Atsushi K Kono, Satoru Takahashi, Ken-Ichi Hirata, Kazuro Sugimura
OBJECTIVE: The aims of this study were to characterize focal myocardial damage of cardiac sarcoidosis by strain analysis and to compare it with late gadolinium enhancement (LGE) and fluorodeoxyglucose (FDG) positron emission tomography. METHODS: We reviewed 208 segments from 13 cardiac sarcoidosis patients and measured the circumferential strain (Ecc) and the strain change per second (Ecc rate). The mean Ecc and Ecc rate values were compared between the FDG(+) and FDG(-), and the LGE(+) and LGE(-) segments using Welch's t test...
April 2, 2018: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/29610956/prognostic-role-of-serial-quantitative-evaluation-of-18-f-fluorodeoxyglucose-uptake-by-pet-ct-in-patients-with-cardiac-sarcoidosis-presenting-with-ventricular-tachycardia
#7
Daniele Muser, Pasquale Santangeli, Simon A Castro, Jackson J Liang, Andres Enriquez, Thomas J Werner, Gaetano Nucifora, Silvia Magnani, Tatsuya Hayashi, Erica S Zado, Fermin C Garcia, David J Callans, Sanjay Dixit, Benoit Desjardins, Francis E Marchlinski, Abass Alavi
BACKGROUND: Positron emission tomography (PET) with18 F-fluorodeoxyglucose (FDG) has shown to be useful in diagnosis, staging and monitoring of cardiac sarcoidosis (CS) but its interpretation is not standardized. OBJECTIVES: We sought to investigate the clinical impact of serial quantitative FDG uptake analysis in patients with CS presenting with ventricular tachycardia (VT) treated by catheter ablation (CA). METHODS: We followed 20 patients (51 ± 9 years, 70% males) with CS and VT who underwent CA, with 92 serial FDG-PET scans (3-10 per patient)...
April 2, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29601561/-cardiac-sarcoidosis-diagnostics-treatment-and-follow-up
#8
REVIEW
Maria Dudziak, Hanna Jankowska, Karolina Dorniak
Sarcoidosis is a generalised granulomatous disorder of unknown aetiology. Cardiac involvement may affect conduction system, myocardium, valvular apparatus and pericardium. Clinical spectrum ranges from asymptomatic involvement to sudden cardiac death. Patients with biopsy-proven extracardiac sarcoidosis should be screened for cardiac involvement (standard ECG, 24-hour Holter ECG, echocardiography) and in case of any abnormalities found on these tests, more advanced diagnostic methods should be used. Steroid treatment is still the mainstay of therapy in cardiac sarcoidosis...
March 27, 2018: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29566033/management-of-sudden-cardiac-death-in-cardiac-sarcoidosis-using-the-wearable-cardioverter-defibrillator
#9
Dirk Skowasch, Steven Ringquist, Georg Nickenig, René Andrié
BACKGROUND: Patients with cardiac sarcoidosis are at increased risk of ventricular tachycardia/fibrillation. OBJECTIVE: We tested the hypothesis that the wearable cardioverter defibrillator can be used to mitigate the risk of sudden cardiac death among cardiac sarcoidosis patients. METHODS: A retrospective review of the commercial database identified cardiac sarcoidosis patients who wore the wearable cardioverter defibrillator. Evidence for cardiac sarcoidosis diagnosis as well as demographic, co-morbidity and left ventricular ejection fraction were provided by patient clinical records...
2018: PloS One
https://www.readbyqxmd.com/read/29560563/diagnostic-value-of-quantitative-assessment-of-cardiac-18-f-fluoro-2-deoxyglucose-uptake-in-suspected-cardiac-sarcoidosis
#10
Adrien Lebasnier, Damien Legallois, Boris Bienvenu, Emmanuel Bergot, Cédric Desmonts, Gérard Zalcman, Denis Agostini, Alain Manrique
OBJECTIVE: The identification of cardiac sarcoidosis is challenging as there is no gold standard consensually admitted for its diagnosis. The aim of this study was to evaluate the diagnostic value of the assessment of cardiac dynamic18 F-fluoro-2-deoxyglucose positron emission tomography (18 F-FDG PET/CT) and net influx constant (Ki) in patients suspected of cardiac sarcoidosis. METHODS: Data obtained from 30 biopsy-proven sarcoidosis patients suspected of cardiac sarcoidosis who underwent a 50-min list-mode cardiac dynamic18 F-FDG PET/CT after a 24 h high-fat and low-carbohydrate diet were analyzed...
March 20, 2018: Annals of Nuclear Medicine
https://www.readbyqxmd.com/read/29557112/isolated-cardiac-sarcoidosis-presenting-with-stroke
#11
Masanari Kuwabara, Rieko Niitsu Ishimura, Sugao Ishiwata, Minoru Ohno
No abstract text is available yet for this article.
March 2018: Korean Circulation Journal
https://www.readbyqxmd.com/read/29538030/11c-4dst-pet-ct-imaging-of-cardiac-sarcoidosis-comparison-with-18f-fdg-and-cardiac-mri
#12
Masatoshi Hotta, Ryogo Minamimoto, Shuji Kubota, Toru Awaya, Yukio Hiroi
A 75-year-old woman with a history of sarcoidosis presenting with low cardiac output and complete right bundle-branch block underwent 4'-[methyl-C]-thiothymidine (4DST) PET/CT after cardiac MRI and FDG PET/CT for the evaluation of suspected cardiac sarcoidosis (CS) before treatment. Cardiac MRI revealed late gadolinium enhancement on the anterior-to-lateral and posterior wall, indicating CS. FDG uptake was shown on the anterior-to-lateral wall, but not on the posterior wall. In contrast, 4DST uptake was demonstrated on both anterior-to-lateral and posterior walls...
June 2018: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29524169/clinical-use-of-cardiac-pet-mri-current-state-of-the-art-and-potential-future-applications
#13
REVIEW
Patrick Krumm, Stefanie Mangold, Sergios Gatidis, Konstantin Nikolaou, Felix Nensa, Fabian Bamberg, Christian la Fougère
Combined PET/MRI is a novel imaging method integrating the advances of functional and morphological MR imaging with PET applications that include assessment of myocardial viability, perfusion, metabolism of inflammatory tissue and tumors, as well as amyloid deposition imaging. As such, PET/MRI is a promising tool to detect and characterize ischemic and non-ischemic cardiomyopathies. To date, the greatest benefit may be expected for diagnostic evaluation of systemic diseases and cardiac masses that remain unclear in cardiac MRI, as well as for clinical and scientific studies in the setting of ischemic cardiomyopathies...
May 2018: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/29519901/robotically-guided-left-ventricular-biopsy-to-diagnose-cardiac-sarcoidosis-a-multidisciplinary-innovation-leading-to-first-in-human-case
#14
Arvind Bhimaraj, Barry Trachtenberg, Miguel Valderrábano
No abstract text is available yet for this article.
March 2018: Circulation. Heart Failure
https://www.readbyqxmd.com/read/29519356/spectrum-of-restrictive-and-infiltrative-cardiomyopathies-part-2-of-a-2-part-series
#15
REVIEW
Naveen L Pereira, Martha Grogan, G William Dec
Restrictive cardiomyopathies are the least common form of heart muscle disease. They are characterized as infiltrative and noninfiltrative, storage diseases, and endomyocardial disorders. Genetic diseases commonly present during childhood or adolescence. However, a growing percentage of elderly patients with heart failure with preserved ejection fraction are being recognized as having forms of restrictive cardiomyopathy, particularly cardiac amyloidosis. Noninvasive evaluation has replaced endomyocardial biopsy in the diagnostic evaluation of most suspected etiologies...
March 13, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29519355/spectrum-of-restrictive-and-infiltrative-cardiomyopathies-part-1-of-a-2-part-series
#16
REVIEW
Naveen L Pereira, Martha Grogan, G William Dec
Restrictive cardiomyopathies are the least common form of heart muscle disease. They are characterized as infiltrative and noninfiltrative, storage diseases, and endomyocardial disorders. Genetic diseases commonly present during childhood or adolescence. However, a growing percentage of elderly patients with heart failure with preserved ejection fraction are being recognized as having forms of restrictive cardiomyopathy, particularly cardiac amyloidosis. Noninvasive evaluation has replaced endomyocardial biopsy in the diagnostic evaluation of most suspected etiologies...
March 13, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29511148/utility-of-left-ventricular-longitudinal-strain-in-the-diagnosis-and-treatment-monitoring-of-cardiac-sarcoidosis
#17
Waldemar Elikowski, Małgorzata Małek-Elikowska, Krzysztof Świerkocki, Dariusz Wróblewski, Andrzej Bolewski, Magdalena Janus
No abstract text is available yet for this article.
February 28, 2018: Polish Archives of Internal Medicine
https://www.readbyqxmd.com/read/29482029/a-contemporary-analysis-of-heart-transplantation-and-bridge-to-transplant-mechanical-circulatory-support-outcomes-in-cardiac-sarcoidosis
#18
Todd C Crawford, David R Okada, J Trent Magruder, Charles Fraser, Nishant Patel, Brian A Houston, Glenn J Whitman, Kaushik Mandal, Kenton J Zehr, Robert S Higgins, Edward S Chen, Hari Tandri, Edward K Kasper, Ryan J Tedford, Stuart D Russell, Nisha A Gilotra
BACKGROUND: Patients with end-stage cardiomyopathy due to cardiac sarcoidosis (CS) may be referred for mechanical circulatory support (MCS) and heart transplantation (HT). We describe outcomes of patients with CS undergoing HT, focusing on the use of MCS as a bridge to transplant (BTT). METHODS: Using the United Network for Organ Sharing Scientific Registry of Transplant Recipients, we identified all adult waitlisted patients and isolated HT recipients from 2006 to 2015...
March 1, 2018: Journal of Cardiac Failure
https://www.readbyqxmd.com/read/29460602/kardial-sarkoidose
#19
Jens Vikse, Stein Ørn, Bas Jeroen de Romijn, Ole Jacob Greve, Katrine Brække Norheim
Sarcoidosis is characterised by granulomatous inflammation in one or more organs, including the heart. Cardiac sarcoidosis generally has non-specific symptoms, and the disease is often diagnosed at a late stage. The condition is associated with cardiomyopathy and arrhythmia and may be fatal.
February 20, 2018: Tidsskrift for Den Norske Lægeforening: Tidsskrift for Praktisk Medicin, Ny Række
https://www.readbyqxmd.com/read/29423905/a-case-of-longitudinal-care-of-a-patient-with-cardiac-sarcoidosis
#20
Rayan Saab, Pradeep Bhambhvani, Ami E Iskandrian, Fadi G Hage
Cardiac sarcoidosis has long been an evasive diagnosis with a spectrum of clinical presentations that extend from asymptomatic to ventricular arrhythmias and sudden cardiac death. The diagnosis has traditionally relied on histology which suffers from the low sensitivity of endomyocardial biopsy due to the patchy nature of the disease in addition to its invasive nature. Due to significant advancements in imaging, it is now possible to accurately identify cardiac sarcoidosis using non-invasive imaging modalities even without histological confirmation...
April 2018: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
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