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cardiac sarcoidosis

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https://www.readbyqxmd.com/read/29141071/usefulness-of-total-12-lead-qrs-voltage-as-a-clue-to-diagnosis-of-patients-with-cardiac-sarcoidosis-severe-enough-to-warrant-orthotopic-heart-transplant
#1
William C Roberts, Tiffany M Becker, Shelley A Hall
Importance: Severe heart failure caused by cardiac sarcoidosis is difficult to diagnosis without biopsy. Objective: To assess whether total electrocardiographic 12-lead QRS voltage may be a clue to diagnosis. Design, Setting, Participants: Case-series study with cases collected at Baylor University Medical Center at Dallas, Dallas, Texas, from January 13, 2005, to January 24, 2017. The clinical records of 16 patients with severe heart failure caused by cardiac sarcoidosis were studied...
November 15, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/29126258/treatment-of-intramural-ventricular-tachycardia-in-cardiac-sarcoidosis-with-transcoronary-ethanol-ablation
#2
Steven M Markowitz, Robert M Minutello, Luke K Kim, James E Ip, George Thomas, Bruce B Lerman
No abstract text is available yet for this article.
November 4, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29121750/novel-ecg-parameters-are-strongly-associated-with-inflammatory-18-f-fdg-pet-findings-in-patients-with-suspected-cardiac-sarcoidosis
#3
Kalle Sipilä, Heikki Tuominen, Atte Haarala, Antti Tikkakoski, Mika Kähönen, Kjell Nikus
BACKGROUND: (18)F-Fluorodeoxyglucose (FDG) positron emission tomography (PET) is a feasible method to investigate the inflammatory activity of the myocardium in cardiac sarcoidosis. However, PET is costly and not as widely available as standard electrocardiogram (ECG). Current ECG findings related to cardiac sarcoidosis are highly non-specific. In this study, our aim was to determine whether novel ECG parameters are associated with pathological PET findings in patients with suspected cardiac sarcoidosis...
December 15, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29094295/patient-page-sarcoidosis-imaging
#4
John P Bois, Panithaya Chareonthaitawee
Optimizing our imaging capabilities for patients with cardiac sarcoidosis is critical as it has diagnostic, prognostic, and therapeutic implications. (18)FDG PET/CT has the highest sensitivity for the detection of CS but requires specific dietary preparation that is difficult for patients to follow which may lead to ineffective suppression of physiologic (18)FDG uptake. This may result in inconclusive scan results in up to 30% of patients undergoing (18)FDG PET/CT imaging for CS. Therefore, it is imperative that we relay to our patients the importance of dietary preparation for CS PET imaging and then provide simple, easy to follow instructions for them...
November 1, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29073361/high-risk-sarcoidosis-current-concepts-and-research-imperatives
#5
William H Sauer, Barney J Stern, Robert Baughman, Daniel A Culver, Walter Royal
Sarcoidosis is a disease with heterogeneous manifestations and outcomes, varying in part based on organ involvement. Specifically, sarcoidosis patients at risk for poor outcomes include individuals with treatment-resistant pulmonary sarcoidosis, including fibrotic pulmonary disease and pulmonary hypertension, as well as those with cardiac, neurologic and multi-organ disease. The limited but available data relating to these high-risk sarcoidosis patients, defined as those patients with presentations requiring medical intervention to avoid progressive disability or premature death, was evaluated as part of the National Heart Lung and Blood Institute's (NHLBI) workshop to improve understanding of these disease manifestations...
October 26, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29066387/clinical-course-of-sarcoidosis-in-world-trade-center-exposed-firefighters
#6
Kerry M Hena, Jennifer Yip, Nadia Jaber, David Goldfarb, Kelly Fullam, Krystal Cleven, William Moir, Rachel Zeig-Owens, Mayris P Webber, Daniel M Spevack, Marc A Judson, Lisa Maier, Andrew Krumerman, Anthony Aizer, Simon D Spivack, Jessica Berman, Thomas K Aldrich, David J Prezant
BACKGROUND: Sarcoidosis is believed to represent a genetically primed, abnormal immune response to an antigen exposure or inflammatory trigger, with both genetic and environmental factors playing a role in disease onset and phenotypic expression. In a population of firefighters with post-World Trade Center (WTC) 9/11/2001 (9/11) sarcoidosis, we have a unique opportunity to describe the clinical course of incident sarcoidosis during the 15 years' postexposure and, on average, 8 years following diagnosis...
October 21, 2017: Chest
https://www.readbyqxmd.com/read/29061522/prognostic-value-of-fluorine-18-fluoro-2-deoxyglucose-positron-emission-computed-tomography-in-patients-with-unexplained-atrioventricular-block
#7
Tamiruddin A Danwade, Soumen Devidutta, Abhijeet B Shelke, Daljeet Kaur Saggu, Sachin D Yalagudri, Chennapragada Sridevi, Nallamala Krishna Reddy, Calambur Narasimhan
BACKGROUND: The cause of atrioventricular conduction block (AVB) remains unexplained in a significant number of patients. Granulomatous myocarditis (GM) is an uncommon but important cause of AVB. Fluorine-18 fluoro-2-deoxyglucose positron emission computed tomography (18-FDG PET) scan has emerged as a sensitive tool for diagnosing GM. OBJECTIVES: The objective of this study was to evaluate the prognostic value of 18-FDG PET scan in patients with unexplained AVB...
October 20, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29052526/cardiac-magnetic-resonance-imaging-indeterminate-negative-cardiac-sarcoidosis-revealed-by-18-f-fluorodeoxyglucose-positron-emission-tomography-two-case-reports-and-a-review-of-the-literature
#8
S C Sasson, R Russo, T Chung, G Chu, I Hunyor, J Williamson, A Murad, A Kane, S Riminton, S Limaye
BACKGROUND: Sarcoidosis is an inflammatory disorder of immune dysregulation characterized by non-caseating granulomas that can affect any organ. Cardiac sarcoidosis is an under-recognized entity that has a heterogeneous presentation and may occur independently or with any severity of systemic disease. Diagnosing cardiac sarcoidosis remains problematic with endomyocardial biopsies associated with a high risk of complications. Several diagnostic algorithms are currently available that rely on histopathology or clinical and radiological measures...
October 20, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29051345/reply-utilizing-and-interpreting-fdg-pet-ct-images-in-patients-referred-for-assessment-of-cardiac-sarcoidosis-the-devil-is-in-the-details
#9
David Birnie, Hiroshi Ohira, Rob Beanlands
No abstract text is available yet for this article.
October 19, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29051269/management-and-long-term-outcomes-of-sarcoidosis-associated-pulmonary-hypertension
#10
Athénaïs Boucly, Vincent Cottin, Hilario Nunes, Xavier Jaïs, Abdelatif Tazi, Grégoire Prévôt, Martine Reynaud-Gaubert, Claire Dromer, Catherine Viacroze, Delphine Horeau-Langlard, Christophe Pison, Emmanuel Bergot, Julie Traclet, Jason Weatherald, Gérald Simonneau, Dominique Valeyre, David Montani, Marc Humbert, Olivier Sitbon, Laurent Savale
Studies reporting the effects of modern strategies with pulmonary arterial hypertension (PAH)-targeted therapies in sarcoidosis-associated pulmonary hypertension (S-APH) are limited.Clinical and haemodynamic data from newly diagnosed patients with severe S-APH (mean pulmonary artery pressure (mPAP) >35 mmHg or mPAP 25-35 mmHg with cardiac index <2.5 L·min(-1)·m(-2)) were collected from the French Pulmonary Hypertension Registry between 2004 and 2015.Data from 126 patients with severe S-APH were analysed (mean±sd age 57...
October 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/29048937/executive-summary-of-the-nhlbi-workshop-report-leveraging-current-scientific-advances-to-better-understand-sarcoidosis-variability-and-improve-outcomes
#11
Lisa A Maier, Elliott D Crouser, William J Martin, Jerry Eu
Sarcoidosis is a systemic granulomatous disease that primarily affects the lung; it is associated with significant disparities, more commonly impacting those in the prime of their lives, age 20-50, with a second peak after age 60, Blacks, and women. However, the burden of disease, the ability to diagnose and prognose organ involvement and course, as well as specific treatment and management options, and disease pathogenesis remain poorly understood. As a result, the National Heart Lung and Blood Institute (NHLBI) undertook a sarcoidosis workshop "Leveraging Current Scientific Advancements to Understand Sarcoidosis Variability and Improve Outcomes" to help address these issues by defining the scientific and clinical priorities to improve sarcoidosis care...
October 19, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/29043557/a-joint-procedural-position-statement-on-imaging-in-cardiac-sarcoidosis-from-the-cardiovascular-and-inflammation-infection-committees-of-the-european-association-of-nuclear-medicine-the-european-association-of-cardiovascular-imaging-and-the-american-society
#12
Riemer H J A Slart, Andor W J M Glaudemans, Patrizio Lancellotti, Fabien Hyafil, Ron Blankstein, Ronald G Schwartz, Wael A Jaber, Raymond Russell, Alessia Gimelli, François Rouzet, Marcus Hacker, Olivier Gheysens, Sven Plein, Edward J Miller, Sharmila Dorbala, Erwan Donal
No abstract text is available yet for this article.
October 17, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29036970/-update-on-the-diagnosis-and-management-of-cardiac-sarcoidosis
#13
Q Zhu, X Q Hu, S H Zhou
No abstract text is available yet for this article.
September 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/29035991/myocardial-perfusion-spect-and-cardiac-mr-correlative-imaging
#14
Ashley E Prosper, Patrick M Colletti
An institutional review board-approved retrospective review of 55 patients who received cardiac MRI within 1 year of myocardial SPECT was performed. Forty-nine demonstrated myocardial infarction by MRI. MRI and SPECT agreed in all but 1 case, where SPECT preceded MRI by 97 days. Three cases are presented here: 2 demonstrating congruent MRI and SPECT changes in a vascular distribution status post infarction and a third with a nonvascular pattern of abnormalities related to left ventricular aneurysm in cardiac sarcoidosis...
October 13, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29029004/right-ventricular-thickening-and-extensive-late-gadolinium-enhancement-in-a-patient-with-rare-case-of-isolated-cardiac-sarcoidosis-and-initially-negative-biopsy
#15
Laura Ueberham, Ingo Paetsch, Cosima Jahnke, Karin Klingel, Borislav Dinov
No abstract text is available yet for this article.
September 28, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29021864/sudden-failure-of-ventricular-pacing-and-recovery-in-a-patient-with-cardiac-sarcoidosis
#16
Yosuke Terui, Akihiro Nakamura, Hideaki Endo, Takahide Kadosaka, Takashi Nakata, Tasuku Watanabe, Kenjiro Sato, Masanori Kanazawa, Masateru Kondo, Tohru Takahashi, Eiji Nozaki
A 76-year-old woman with sarcoidosis who had an implantable pacemaker for complete atrioventricular block was admitted with syncope. Electrocardiogram revealed ventricular pacing failure, and a marked rise in the ventricular pacing threshold. (18)F-Fluorodeoxyglucose positron emission tomography (FDG-PET) indicated increased uptake of FDG in the ventricular septum. Three days after steroid therapy, the ventricular pacing threshold reverted to normal, and FDG-PET showed decreased FDG uptake in the ventricular septum...
October 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/29021100/the-value-of-endomyocardial-biopsy-in-diagnosis-and-guiding-therapy
#17
Tayyaba Khan, Dinesh Selvakumar, Siddharth Trivedi, Karan Rao, Mehmet Harapoz, Aravinda Thiagalingam, A Robert Denniss, Winny Varikatt
Endomyocardial biopsy (EMB) is a highly-specialised procedure that is associated with some controversy as to its diagnostic role due to its inconsistency in diagnosing a wide variety of cardiac diseases. Given the advances and sophistication in echocardiography and cardiac magnetic resonance imaging (MRI), the vast majority of cardiac diseases can be diagnosed by these non-invasive procedures. Under-sampling and the fact that biopsy site is limited to the right side of the interventricular septum further limits its value...
October 8, 2017: Pathology
https://www.readbyqxmd.com/read/28984894/a-joint-procedural-position-statement-on-imaging-in-cardiac-sarcoidosis-from-the-cardiovascular-and-inflammation-infection-committees-of-the-european-association-of-nuclear-medicine-the-european-association-of-cardiovascular-imaging-and-the-american-society
#18
(no author information available yet)
This joint position paper illustrates the role and the correct use of echocardiography, radionuclide imaging with 18F-fluorodeoxyglucose positron emission tomography, radionuclide myocardial perfusion imaging and cardiovascular magnetic resonance imaging for the evaluation and management of patients with known or suspected cardiac sarcoidosis. This position paper will aid in standardizing imaging for cardiac sarcoidosis and may facilitate clinical trials and pooling of multi-centre data on cardiac sarcoidosis...
October 1, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28967698/right-ventricular-involvement-and-the-extent-of-left-ventricular-enhancement-with-magnetic-resonance-predict-adverse-outcome-in-pulmonary-sarcoidosis
#19
Jan-Peter Smedema, Robert-Jan van Geuns, Joris Ector, Hein Heidbuchel, Gillian Ainslie, Harry J G M Crijns
AIMS: Cardiac involvement is the main determinant of poor outcomes in sarcoidosis. Right ventricular (RV) dysfunction and left ventricular (LV) late gadolinium enhancement (LGE) have been reported to be predictive of adverse outcome in non-ischaemic cardiomyopathies. The aim of our study was to determine whether delayed RV LGE with cardiovascular magnetic resonance would be predictive of adverse events in addition to LV LGE during the long-term follow-up of pulmonary sarcoidosis patients...
October 2, 2017: ESC Heart Failure
https://www.readbyqxmd.com/read/28956545/disseminated-mycobacterium-chimaera-infection-after-open-heart-surgery-in-an-italian-woman-a-case-report-and-a-review-of-the-literature
#20
Sheila Chiesi, Daniela Piacentini, Nicola Duccio Salerno, Dora Luise, Marta Peracchi, Ercole Concia, Angelo Cazzadori, Enrico Piovan, Massimiliano Lanzafame
We report the first Italian case of Mycobacterium chimaera disseminated infection in a patient with a history of cardiac surgery. The patient was initially diagnosed with sarcoidosis and started on immunosuppressive therapy. Ten months later she developed a vertebral osteomyelitis: M. chimaera was isolated from bone specimen. A review of the literature shows that M. chimaera infection occurs specifically in this population of patients, due to contamination of heater-cooler units used during cardiosurgery. Devices responsible for the transmission were produced by Sorin Group Deutschland...
September 1, 2017: Le Infezioni in Medicina
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