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https://www.readbyqxmd.com/read/28077118/malat1-promoted-invasiveness-of-gastric-adenocarcinoma
#1
Na Keum Lee, Jung Hwa Lee, Cristina Ivan, Hui Ling, Xinna Zhang, Chan Hyuk Park, George A Calin, Sang Kil Lee
BACKGROUND: Gastric cancer is the second leading cause of cancer globally, and the mechanism of its pathogenesis is still largely unknown. Recently, non-coding RNAs have been recognized to promote metastasis in various cancers, including gastric cancer. METHODS: We found that metastasis associated lung adenocarcinoma transcript-1 (MALAT1) is upregulated in gastric cancer tissue compared to adjacent normal tissue, as determined by microarray and subsequent qRT-PCR, then investigated the impact of MALAT1 on apoptosis, cell proliferation, and the cell cycle to dissect the carcinogenesis of gastric cancer, and examined mechanisms of invasion and metastasis...
January 11, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28074980/-implications-of-chilean-legal-framework-in-teen-pregnancy-prevention-conflict-and-insecurity-in-health-professionals
#2
Carolina Luttges D, Carolina Leyton M, Ingrid Leal F, Paulina Troncoso E, Temístocles Molina G
BACKGROUND: Teenage pregnancy is a psychosocial and multifactorial problem described as a lack of exercise of rights in sexual and reproductive health. There are important aspects in the doctor-patient relationship and confidentiality that directly affect the continuity and quality of care. There are controversies in the laws relating to the provision of contraception and confidentiality, and those that protect the sexual indemnity, especially in adolescents under 14 years. AIM: To describe the implications of the legal framework for professional midwives in the care of adolescents younger than 14 years in sexual and reproductive health...
October 2016: Revista Médica de Chile
https://www.readbyqxmd.com/read/28073618/characteristics-of-adolescents-lacking-provider-recommended-human-papillomavirus-vaccination
#3
Melinda Krakow, Anna Beavis, Olivia Cosides, Anne F Rositch
PURPOSE: To characterize subgroups of teens in the United States for whom provider recommendation is less likely to impact human papillomavirus (HPV) vaccine initiation. METHODS: We analyzed provider-verified vaccination data from the Centers for Disease Control and Prevention's 2014 National Immunization Survey-Teen. Poisson regression models identified characteristics associated with the lack of HPV vaccine initiation among teens who received a provider recommendation (n = 12,742)...
January 7, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28073557/diatom-nitzschia-navis-varingica-bacillariophyceae-and-its-domoic-acid-production-from-the-mangrove-environments-of-malaysia
#4
Suh Nih Tan, Sing Tung Teng, Hong Chang Lim, Yuichi Kotaki, Stephen S Bates, Chui Pin Leaw, Po Teen Lim
The distribution of the toxic pennate diatom Nitzschia was investigated at four mangrove areas along the coastal brackish waters of Peninsular Malaysia. Eighty-two strains of N. navis-varingica were isolated and established, and their identity confirmed morphologically and molecularly. Frustule morphological characteristics of the strains examined are identical to previously identified N. navis-varingica, but with a sightly higher density of the number of areolae per 1μm (4-7 areolae). Both LSU and ITS rDNAs phylogenetic trees clustered all strains in the N...
December 2016: Harmful Algae
https://www.readbyqxmd.com/read/28073527/new-scenario-for-speciation-in-the-benthic-dinoflagellate-genus-coolia-dinophyceae
#5
Chui Pin Leaw, Toh Hii Tan, Hong Chang Lim, Sing Tung Teng, Hwa Lin Yong, Kirsty F Smith, Lesley Rhodes, Matthias Wolf, William C Holland, Mark W Vandersea, R Wayne Litaker, Patricia A Tester, Haifeng Gu, Gires Usup, Po Teen Lim
In this study, inter- and intraspecific genetic diversity within the marine harmful dinoflagellate genus Coolia Meunier was evaluated using isolates obtained from the tropics to subtropics in both Pacific and Atlantic Ocean basins. The aim was to assess the phylogeographic history of the genus and to clarify the validity of established species including Coolia malayensis. Phylogenetic analysis of the D1-D2 LSU rDNA sequences identified six major lineages (L1-L6) corresponding to the morphospecies Coolia malayensis (L1), C...
May 2016: Harmful Algae
https://www.readbyqxmd.com/read/28073499/physiological-and-transcriptional-responses-to-inorganic-nutrition-in-a-tropical-pacific-strain-of-alexandrium-minutum-implications-for-the-saxitoxin-genes-and-toxin-production
#6
Kieng Soon Hii, Po Teen Lim, Nyuk Fong Kon, Yoshinobu Takata, Gires Usup, Chui Pin Leaw
Saxitoxins (STXs) constitute a family of potent sodium channel blocking toxins, causative agents of paralytic shellfish poisoning (PSP), and are produced by several species of marine dinoflagellates and cyanobacteria. Two STX-core genes, sxtA and sxtG, have been well elucidated in Alexandrium but the expression of these genes under various nutritional modes in tropical species remains unclear. This study investigates the physiological responses of a tropical Pacific strain of Alexandrium minutum growing with nitrate or ammonium, and with various nitrogen to phosphorus (N:P) supply ratios...
June 2016: Harmful Algae
https://www.readbyqxmd.com/read/28069493/-just-wear-dark-underpants-mainly-learning-from-adolescents-and-young-adults-experiences-with-early-discontinuation-of-the-contraceptive-implant
#7
Britt Lunde, Lisa Littman, Samantha Stimmel, Rima Rana, Adam Jacobs, Carol R Horowitz
STUDY OBJECTIVE: Long acting reversible contraception, including the contraceptive implant, is recommended for teens and young women. However, some young women discontinue the implant early, and we seek to better understand their experiences. DESIGN: / Setting / Participants: We conducted interviews with 16 females ages 14 to 24 presenting for removal of the contraceptive implant within 6 months after placement at out-patient adolescent, family medicine and obstetrics and gynecology clinics...
January 6, 2017: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/28065571/exposure-to-ddt-and-diabetic-nephropathy-among-mexican-americans-in-the-1999-2004-national-health-and-nutrition-examination-survey
#8
Charles J Everett, Olivia M Thompson, Clara E Dismuke
Concentrations of the pesticide DDT (dichlorodiphenyltrichloroethane) and its metabolite DDE (dichlorodiphenyldichloroethylene), in the blood of Mexican Americans, were evaluated to determine their relationships with diabetes and diabetic nephropathy. The data were derived from the National Health and Nutrition Examination Survey (NHANES) 1999-2004 (unweighted N = 1,411, population estimate = 13,760,609). The sample included teens, 12-19 years old, which accounted for 19.8% of the data. The time of the study overlapped the banning of DDT in Mexico in the year 2000, and those participants born in Mexico were exposed to DDT before they immigrated to the US...
January 5, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28065206/iowa-gambling-task-performance-prospectively-predicts-changes-in-glycemic-control-among-adolescents-with-type-1-diabetes
#9
Yana Suchy, Tara L Queen, Bryce Huntbach, Deborah J Wiebe, Sara L Turner, Jonathan Butner, Caitlin S Kelly, Perrin C White, Mary Murray, Michael Swinyard, Cynthia A Berg
OBJECTIVES: Good glycemic control is an important goal of diabetes management. Late adolescents with type 1 diabetes (T1D) are at risk for poor glycemic control as they move into young adulthood. For a subset of these patients, this dysregulation is extreme, placing them at risk for life-threatening health complications and permanent cognitive declines. The present study examined whether deficiency in emotional decision making (as measured by the Iowa Gambling Task; IGT) among teens with T1D may represent a neurocognitive risk factor for subsequent glycemic dysregulation...
January 9, 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/28061921/bipolar-disorder-in-aviation-medicine
#10
Alpo Vuorio, Tanja Laukkala, Pooshan Navathe, Bruce Budowle, Robert Bor, Antti Sajantila
BACKGROUND: One of the most difficult challenges in aviation medicine is to diagnose, as early as possible, pilots with psychiatric disorders that may impair pilot performance and increase the risk of incidents and accidents. This diagnosis applies particularly to bipolar disorder (BD), where return to flying duty is not an option in the majority of cases. BD is a long-term mental disorder presenting remittent depressive, hypomanic, manic, or mixed episodes between low symptomatic or asymptomatic intermediate periods...
January 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28061392/association-of-environmental-indicators-with-teen-alcohol-use-and-problem-behavior-teens-observations-vs-objectively-measured-indicators
#11
Hilary F Byrnes, Brenda A Miller, Christopher N Morrison, Douglas J Wiebe, Marcie Woychik, Sarah E Wiehe
: Most prior studies use objectively measured data (e.g., census-based indicators) to assess contextual risks. However, teens' observations might be more important for their risk behavior. OBJECTIVES: 1) determine relationships between observed and objective indicators of contextual risks 2) determine relations of observed and objective indicators with teen alcohol use and problem behavior. Teens aged 14-16 (N=170) carried GPS-enabled smartphones for one month, with locations documented...
January 3, 2017: Health & Place
https://www.readbyqxmd.com/read/28058853/postpartum-adolescents-contraceptive-counselling-preferences
#12
Stephanie Sober, Judy A Shea, Allison G Shaber, Paul G Whittaker, Courtney A Schreiber
OBJECTIVES: The optimal approach for provision and timing of postpartum contraceptive counselling for adolescents has not been established. To reduce repeat pregnancies from current USA levels of nearly 20%, a better understanding is needed of postpartum adolescent females' preferences regarding contraceptive counselling and delivery. METHODS: Semi-structured interviews with 30 USA postpartum teens (97% Black) explored pregnancy prevention and contraceptive counselling...
January 6, 2017: European Journal of Contraception & Reproductive Health Care
https://www.readbyqxmd.com/read/28058851/postintervention-effects-of-click-city-%C3%A2-alcohol-on-changing-etiological-mechanisms-related-to-the-onset-of-heavy-drinking
#13
Judith S Gordon, Judy A Andrews, Sarah H Hampson, Barbara Gunn, Steven M Christiansen, Thomas Jacobs
INTRODUCTION: Alcohol consumption, including heavy drinking, is the fourth leading preventable cause of death in the United States. Youth who engage in heavy drinking are likely to experience a number of problems associated with their use. In 2015, U.S. prevalence of heavy drinking was 17% among 12th graders. These data suggest a clear need for conducting alcohol prevention activities among youth. METHOD: We designed the Click City(®): Alcohol program for 7th graders, with a booster in 8th grade...
January 1, 2017: Health Education & Behavior: the Official Publication of the Society for Public Health Education
https://www.readbyqxmd.com/read/28056541/a-randomized-trial-of-user-controlled-text-messaging-to-improve-asthma-outcomes
#14
Maria T Britto, Jennifer M Rohan, Cassandra M Dodds, Terri L Byczkowski
We enrolled 64 patients age 12 to 22 years with a diagnosis of poorly controlled persistent asthma in a 6-month longitudinal crossover study. During the 3 intervention months, participants created personalized text messages to be sent to their phones. Adherence was objectively monitored in 22 of the participants. The adolescent participants gave high ratings on the acceptability of the text messaging system. Asthma control improved from baseline to month 1 regardless of whether teens were in the texting or control group...
January 1, 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/28052706/research-brief
#15
Erin Schoenfelder, Connor McCabe, Aurora Fife, Lisa Herzig, Kym Ahrens
OBJECTIVE: Adolescents with ADHD are at risk of functional problems that may be mitigated by consistent ADHD treatment. This study pilots a brief intervention for adolescents with ADHD and their parents to increase treatment knowledge and family motivation to seek treatment. METHOD: The 3-hr curriculum was developed by a multidisciplinary team and included psychoeducation, goal setting, and motivational interviewing. Fifteen adolescents and 20 caregivers participated in the workshop, completed pre- and post-test assessments, and reported on acceptability...
January 1, 2017: Journal of Attention Disorders
https://www.readbyqxmd.com/read/28047841/tu-h-207a-04-how-patient-positioning-in-ct-affects-more-than-the-aec-image-noise-uniformity-and-ct-number-changes-as-a-function-of-positioning
#16
T Szczykutowicz, A Duplissis, D Miller
PURPOSE: Studies dealing with patient positioning in CT have mainly dealt with dose and image noise changes. For diagnosis, only dose decreases can negatively affect the diagnostic utility of the exam via an increase in image noise. However, a little studied consequence of poor positioning is CT number and noise uniformity changes. METHODS: An anthropomorphic phantom was imaged in 2 cm vertical steps between the highest and lowest couch positions. CT number and noise were measured using regions of interest (ROI) in the upper-thorax, mid-thorax, and abdomen...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28044048/dietary-supplements-and-young-teens-misinformation-and-access-provided-by-retailers
#17
Maguire Herriman, Laura Fletcher, Alexis Tchaconas, Andrew Adesman, Ruth Milanaik
BACKGROUND AND OBJECTIVE: Despite the American Academy of Pediatrics' recommendations against pediatric use of creatine and testosterone boosters, research suggests that many young teenagers take these dietary supplements. Our objective was to determine to what extent health food stores would recommend and/or sell creatine and testosterone boosters to a 15-year-old boy customer. METHODS: Research personnel posing as 15-year-old high school athletes seeking to increase muscle strength contacted 244 health food stores in the United States via telephone...
January 2, 2017: Pediatrics
https://www.readbyqxmd.com/read/28042174/reexamining-the-association-of-maternal-age-and-marital-status-at-first-birth-with-youth-educational-attainment
#18
Fenaba R Addo, Sharon Sassler, Kristi Williams
Using data from the linked Children and Young Adult sample (N = 2,865) of the NLSY79, we reexamined the association of maternal age and marital status at birth with youth high school completion, assessing multiple age categories and race/ethnic variations. Youth born to older teen mothers were no more likely to graduate from high school than those born to the youngest teen mothers. Although delaying childbirth to young adulthood (age 20-24) was associated with greater odds of children's high school completion compared to the earliest teen births, those born to young adult mothers were disadvantaged compared to those born to mothers age 25 or older...
October 2016: Journal of Marriage and the Family
https://www.readbyqxmd.com/read/28035863/healthy-sleep-in-teens
#19
(no author information available yet)
No abstract text is available yet for this article.
January 1, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28031378/cigarette-graphic-warning-labels-are-not-created-equal-they-can-increase-or-decrease-smokers-quit-intentions-relative-to-text-only-warnings
#20
Abigail T Evans, Ellen Peters, Abigail Shoben, Louise Meilleur, Elizabeth G Klein, Mary Kate Tompkins, Daniel Romer, Martin Tusler
INTRODUCTION: Cigarette graphic-warning labels elicit negative emotion. Research suggests negative emotion drives greater risk perceptions and quit intentions through multiple processes. The present research compares text-only warning effectiveness to that of graphic warnings eliciting more or less negative emotion. METHODS: Nationally representative online panels of 736 adult smokers and 469 teen smokers/vulnerable smokers were randomly assigned to view one of three warning types (text-only, text with low-emotion images, or text with high-emotion images) four times over two weeks...
December 28, 2016: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
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