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Kensuke Asakura, Shunichi Yanai, Shotaro Nakamura, Keisuke Kawaski, Makoto Eizuka, Kazuyuki Ishida, Masaki Endo, Tamotsu Sugai, Kiyoshi Migita, Takayuki Matsumoto
RATIONALE: Familial Mediterranean fever (FMF) is the most common form of autoinflammatory disease. We report a rare case of FMF with gastrointestinal lesions mimicking Crohn disease. PATIENT CONCERNS: A 21-year-old Japanese man was referred to our institution, complaining of refractory diarrhea and weight loss of 14 kg during the past two years. He had presented with recurrent fever, abdominal pain, anal fistula and stomatitis. His father and one of his brothers had ulcerative colitis...
January 2018: Medicine (Baltimore)
Satoru Esumi, Yoichi Kawaski, Akihiko Nakamoto, Hidenori Sagara, Yutaka Gomita, Yoshihisa Kitamura, Toshiaki Sendo
A motivational deficit (the loss of pleasure or interest in previously rewarding stimuli) is one of the core symptoms of major depression, and valid models evaluating the motivational effects of drugs are needed. It was recently demonstrated that the priming stimulation effect in the runway model of intracranial self-stimulation (ICSS) can be used as a model system to study the motivational effects of drugs. However, the characteristics of this novel experimental model have not been fully clarified. In this study, we investigated the effects of nomifensine and imipramine in the runway ICCS model, forced swim tests, and locomotor activity tests to differentiate motivation from affective-like states...
November 15, 2013: European Journal of Pharmacology
Sv Reddy, Tj Forbes, K Chintala
No abstract text is available yet for this article.
April 2005: Images in Paediatric Cardiology
Abdul Gaffar Billoo, Saira Waqar Lone, Salman Siddiqui, Huba Atiq
Kawasaki disease, also known as mucocutaneous lymph node syndrome or infantile polyarteritis nodosa is an acute febrile vasculitis of unknown etiology with a predilection for coronary arteries and potential for aneurysm formation. In Incomplete Kawasaki disease, children with fever lack the sufficient number of criteria to fulfill the epidemiologic case definition and are diagnosed when coronary artery disease is detected. We present a case report of a one and a half years old girl who came with features of incomplete Kawasaki disease, high grade fever, irritability, history of conjunctivitis and cracking of lips...
January 2009: JPMA. the Journal of the Pakistan Medical Association
A Hashmi, C Lazzam, B W McCrindle, L N Benson
Coronary artery lesions can develop in Kawaski disease as a major complication, and result in aneurysm formation and stenosis. Reported is the evolution of important coronary artery stenosis in a pediatric patient managed with an endovascular stent.
March 1999: Catheterization and Cardiovascular Interventions
I Kawaski, K Lochner
No abstract text is available yet for this article.
November 1997: Cancer Causes & Control: CCC
M Bonno, E Azuma, T Nakano, M Higashikawa, H Kawaski, H Nishihara, M Obata, M Umemoto, H Sakatoku, Y Komada, M Ito, M Nagai, M Sakurai
A 4-year-old boy with Diamond-Blackfan anemia and a history of multiple transfusions underwent umbilical cord blood transplantation from his HLA-identical female sibling born by vaginal delivery at 38 weeks. The patient was prepared with busulfan, cyclophosphamide and antilymphocyte globulin. Methotrexate and cyclosporin A were given for the prophylaxis of GVHD. Regimen-related toxicity was not observed and successful engraftment occurred, including the erythroid series. No evidence of acute or chronic GVHD has been observed for 14 months after transplantation...
January 1997: Bone Marrow Transplantation
M Ema, T Itami, H Kawaski, S Kanoh
The teratogenicity of Tween 60 was studied in Wistar rats. Pregnant rats were given Tween 60 at a dose of 0, 0.1, 1.0 or 10% in the diet from day 7 to day 14 of pregnancy. Daily intakes of Tween 60 were 99 mg/kg for the 0.1% group, 960 mg/kg for the 1.0% group and 7693 mg/kg for the 10% group. No change induced by Tween 60 was detected in the number, sex ratio and body weight of live fetuses. External, skeletal and internal examinations of the fetuses revealed no evidence of teratogenesis. It could be concluded that Tween 60 has no harmful effects on the prenatal development of the rat offspring at doses employed in the present study...
1988: Drug and Chemical Toxicology
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