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https://www.readbyqxmd.com/read/28065380/iterative-model-reconstruction-reduces-calcified-plaque-volume-in-coronary-ct-angiography
#1
Mihály Károlyi, Bálint Szilveszter, Márton Kolossváry, Richard A P Takx, Csilla Celeng, Andrea Bartykowszki, Ádám L Jermendy, Alexisz Panajotu, Júlia Karády, Rolf Raaijmakers, Walter Giepmans, Béla Merkely, Pál Maurovich-Horvat
OBJECTIVE: To assess the impact of iterative model reconstruction (IMR) on calcified plaque quantification as compared to filtered back projection reconstruction (FBP) and hybrid iterative reconstruction (HIR) in coronary computed tomography angiography (CTA). METHODS: Raw image data of 52 patients who underwent 256-slice CTA were reconstructed with IMR, HIR and FBP. We evaluated qualitative, quantitative image quality parameters and quantified calcified and partially calcified plaque volumes using automated software...
February 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28052860/increased-prevalence-of-coronary-plaque-in-patients-with-psoriatic-arthritis-without-prior-diagnosis-of-coronary-artery-disease
#2
Jiayun Shen, Ka-Tak Wong, Isaac T Cheng, Qing Shang, Edmund K Li, Priscilla Wong, Emily W Kun, Mei Yan Law, Ronald Yip, Isaac Yim, Shirley Ying, Martin Li, Tena K Li, Chun-Kwok Wong, Tracy Y Zhu, Jack Jock-Wai Lee, Mimi Chang, Alex Pui-Wai Lee, Lai-Shan Tam
OBJECTIVES: To evaluate coronary atherosclerosis in patients with psoriatic arthritis (PsA) and control subjects using coronary CT angiography (CCTA). METHODS: Ninety consecutive patients with PsA (male: 56(62.2%); 50.3±11.1 years) were recruited. 240 controls (male: 137(57.1%); 49.6±10.7 years) without known cardiovascular (CV) diseases who underwent CCTA due to chest pain and/or multiple CV risk factors were recruited for comparison. RESULTS: Patients with PsA and controls were matched in age, gender and traditional CV risk factors (all p>0...
January 4, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28048223/we-fg-207b-06-plaque-composition-measurement-with-dual-energy-computed-tomography
#3
C Wang, H Ding, S Malkasian, S Molloi
PURPOSE: To investigate the feasibility of characterizing arterial plaque composition in terms of water, lipid and protein or calcium using dual energy computed tomography. Characterization of plaque composition can potentially help distinguish vulnerable from stable plaques. METHODS: Simulations studies were performed by the CT simulator based on ASTRA tomography toolbox. The beam energy for dual energy images was selected to be 80 kVp and 135 kVp. The radiation dose and energy spectrum for the CT simulator were carefully calibrated with respect to a 320-slice CT scanner...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28025263/quantitative-plaque-features-from-coronary-computed-tomography-angiography-to-identify-regional-ischemia-by-myocardial-perfusion-imaging
#4
Mariana Diaz-Zamudio, Tobias A Fuchs, Piotr Slomka, Yuka Otaki, Reza Arsanjani, Heidi Gransar, Guido Germano, Daniel S Berman, Philipp A Kaufmann, Damini Dey
AIMS: We aimed to investigate whether quantitative plaque features measured from coronary CT angiography (CCTA) predict ischemia by myocardial perfusion SPECT imaging (MPI). METHODS AND RESULTS: Hundred and eighty-four consecutive patients (63% males) with suspected-coronary artery disease, undergoing hybrid CCTA, and attenuation corrected solid state (99m)Tc stress/rest MPI and single vessel ischemia were considered. Quantitative analysis of CCTA derived non-calcified plaque (NCP), low-density NCP [< 30 Hounsfield Units (HU)] (LDNCP), calcified and total plaque burdens (%, normalized to vessel volume), maximum diameter stenosis and contrast density difference (CD, maximum difference in HU/lumen area within lesion)...
December 26, 2016: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/27993385/association-of-tobacco-use-and-cessation-with-coronary-atherosclerosis
#5
Michael K Cheezum, Alexander Kim, Marcio S Bittencourt, David Kassop, Alexander Nissen, Dustin M Thomas, Binh Nguyen, Robert J Glynn, Nishant R Shah, Todd C Villines
BACKGROUND AND AIMS: The impact of tobacco use and cessation on atherogenesis remains unclear. We aimed to study the association of tobacco use and prior cessation with the presence, extent and severity of atherosclerosis on coronary computed tomographic angiography (CTA). METHODS: We examined 1798 consecutive symptomatic patients without known coronary artery disease (CAD) referred for CTA, stratified by smoking status (never, current [within 30 days], or former [>30 days before CTA])...
November 16, 2016: Atherosclerosis
https://www.readbyqxmd.com/read/27973332/limitations-of-oct-in-identifying-and-quantifying-lipid-components-an-in-vivo-comparison-study-with-ivus-nirs
#6
Luca Di Vito, Fabrizio Imola, Laura Gatto, Enrico Romagnoli, Ugo Limbruno, Valeria Marco, Andrea Picchi, Antonio Micari, Mario Albertucci, Francesco Prati
AIMS: We assessed the agreement between IVUS-NIRS and OCT to assess lipid plaques in patients with acute coronary syndromes or stable angina. In addition, the impact of both macrophages and calcifications was investigated. METHODS AND RESULTS: Forty-three patients undergoing both IVUS-NIRS and OCT assessment of the culprit and/or non culprit coronary lesions were enrolled. Cross-sections from lipid plaques, calcified plaques and normal appearing vessel tracts were identified and matched with the two imaging techniques...
December 15, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27899854/association-of-neutrophil-to-lymphocyte-ratio-with-the-severity-and-morphology-of-coronary-atherosclerotic-plaques-detected-by-multidetector-computerized-tomography
#7
Ahmet Hakan Ateş, Kudret Aytemir, Duygu Koçyiğit, Muhammed Ulvi Yalcin, Kadri Murat Gürses, Hikmet Yorgun, Uğur Canpolat, Tuncay Hazırolan, Necla Özer
BACKGROUND: Studies have demonstrated a consistent relationship between white blood cell (WBC) counts and coronary artery disease (CAD). The neutrophil/lymphocyte ratio (NLR) has been considered as a potential marker for identifying individuals under risk of CAD and associated events. In this study, we aimed to evaluate whether NLR was associated with the severity and morphology of coronary atherosclerotic plaques shown by multidetector computed tomography (MDCT). METHODS: Our study population consisted of 684 patients who underwent dual-source 64 slice MDCT for the assessment of CAD...
November 2016: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/27835741/plaque-progression-assessed-by-a-novel-semi-automated-quantitative-plaque-software-on-coronary-computed-tomography-angiography-between-diabetes-and-non-diabetes-patients-a-propensity-score-matching-study
#8
Rine Nakanishi, Indre Ceponiene, Kazuhiro Osawa, Yanting Luo, Mitsuru Kanisawa, Nichelle Megowan, Negin Nezarat, Sina Rahmani, Alexander Broersen, Pieter H Kitslaar, Christopher Dailing, Matthew J Budoff
BACKGROUND AND AIMS: We aimed at investigating whether diabetes is associated with progression in coronary plaque components. METHODS: We identified 142 study subjects undergoing serial coronary computed tomography angiography. The resulting propensity score was applied 1:1 to match diabetic patients to non-diabetic patients for clinical risk factors, prior coronary stenting, coronary artery calcium (CAC) score and the serial scan interval, resulting in the 71 diabetes and 71 non-diabetes patients...
December 2016: Atherosclerosis
https://www.readbyqxmd.com/read/27824692/long-term-marathon-running-is-associated-with-low-coronary-plaque-formation-in-women
#9
William O Roberts, Robert S Schwartz, Stacia Merkel Kraus, Jonathan G Schwartz, Gretchen Peichel, Ross F Garberich, John R Lesser, Stephen N Oesterle, Kelly K Wickstrom, Thomas Knickelbine, Kevin M Harris
INTRODUCTION: Marathon running is presumed to improve cardiovascular risk, but health benefits of high volume running are unknown. High resolution coronary computed tomography angiography (CCTA) and a cardiac risk factor assessment were completed in women with long term marathon running histories to compare to sedentary women with similar risk factors. METHODS: Women who had run at least one marathon per year for 10-25 years underwent CCTA, 12-lead ECG, blood pressure and heart rate measurement, lipid panel, and a demographic/health risk factor survey...
November 7, 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27738787/integrated-non-invasive-approach-to-atherosclerosis-with-cardiac-ct-and-carotid-ultrasound-in-patients-with-suspected-coronary-artery-disease
#10
Ludovico La Grutta, Marta Marasà, Patrizia Toia, Daniele Ajello, Domenico Albano, Erica Maffei, Emanuele Grassedonio, Giuseppina Novo, Massimo Galia, Giuseppe Caruso, Salvatore Novo, Filippo Cademartiri, Massimo Midiri
OBJECTIVE: The aim of the study was to compare the atherosclerotic disease in the coronary and carotid arteries in patients who underwent non-invasive imaging for suspected stable coronary artery disease (CAD). MATERIALS AND METHODS: 107 patients (64 men, age 59 ± 12) with atypical chest pain underwent cardiac CT (CCT) and carotid ultrasound (US) on the same day. Severity (obstructive or not-obstructive disease), location, shape, and composition of atherosclerotic plaques in the two districts were evaluated...
January 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/27733980/comparison-of-coronary-plaque-coronary-artery-calcification-and-major-adverse-cardiac-events-in-chinese-outpatients-with-and-without-type-2-diabetes
#11
Lijie Zhu, Jingjing Liu, Chuanyu Gao, Wenli Zhao, Jing Que, Xianpei Wang, Datun Qi, Jun Liu, Wentao Xiao, Juanjuan Yan, Wentao Li, You Zhang, Honghui Yang
OBJECTIVE: Diabetes substantially increases the risk of cardiovascular disease (CAD) and is associated with an increased risk of CAD mortality. The purpose of this study was to investigate the differences in coronary artery plaque, coronary artery calcification (CAC) measured in outpatients with and without type 2 diabetes, and the occurrence rate of a major adverse cardiac event (MACE) throughout follow-up with the same patients. METHODS: Five hundred eighty-eight outpatients with suspected CAD comprising 208 diabetic and 380 non-diabetic patients were enrolled in this study...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27733727/epicardial-adipose-tissue-as-a-predictor-for-the-development-of-non-calcified-coronary-plaque
#12
Koichi Kaikita
No abstract text is available yet for this article.
October 12, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27721862/association-of-neutrophil-lymphocyte-ratio-with-plaque-morphology-in-patients-with-asymptomatic-intermediate-carotid-artery-stenosis
#13
İsa Öner Yüksel, Erkan Köklü, Şakir Arslan, Göksel Çağırcı, Eylem Özaydın Göksu, Pınar Koç, Serkan Çay, Filiz Kızılırmak
BACKGROUND AND OBJECTIVES: Non-calcified carotid plaques are more unstable than calcified plaques, and they are associated with a higher risk of rupture, thromboembolism, and consequently, stroke. The purpose of the present study is to compare calcified and non-calcified plaques that cause intermediate carotid artery stenosis with respect to neutrophil/lymphocyte ratio (NLR). SUBJECTS AND METHODS: A total number of 139 asymptomatic patients with 50-70% stenosis of the carotid artery were included in this study...
September 2016: Korean Circulation Journal
https://www.readbyqxmd.com/read/27714714/evaluation-of-mean-platelet-volume-and-platelet-distribution-width-in-patients-with-asymptomatic-intermediate-carotid-artery-plaque
#14
Fatih Yılmaz, Erkan Köklü, Filiz Kizilirmak Yilmaz, Elif Sarıönder Gencer, Ahmet Şükrü Alparslan, Özlem Yıldırımtürk
BACKGROUND: Platelets play a significant role in the pathogenesis of atherosclerosis. In atherosclerotic plaques, the risk of plaque rupture is more crucial than the severity of stenosis they cause. Non-calcified carotid artery plaques are more unstable than calcified plaques, and they are associated with a higher risk of rupture, thromboembolism and consequently, stroke. AIM: Purpose of the present study is to compare calcified and non-calcified plaques that cause intermediate carotid artery stenosis with respect to mean platelet volume (MPV) and platelet distribution width (PDW)...
October 7, 2016: Kardiologia Polska
https://www.readbyqxmd.com/read/27677761/national-trends-among-radiologists-in-reporting-coronary-artery-calcium-in-non-gated-chest-computed-tomography
#15
Jacobo Kirsch, Felipe Martinez, David Lopez, Gian M Novaro, Craig R Asher
Coronary artery calcification (CAC) is a known risk factor for adverse outcomes in the general population and in patients with coronary artery disease. We performed a survey of United States radiologists to evaluate the trends in reporting the presence or absence of CAC on NCCT examinations. An 11 multiple-choice questionnaire was distributed to members of the American College of Radiology, and 530 members participated in the study. Eighty-seven percent of the analyzed group report the presence of CAC on standard CT scans of the chest, and approximately half them (52 %) use a qualitative modifier...
September 27, 2016: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/27633455/application-of-dual-source-ct-coronary-angiography-in-type-2-diabetic-patients-with-symptomatic-coronary-heart-disease
#16
Ci He, Peng Wang, Fei-Zhou Du, Zhi-Gang Yang
OBJECTIVE: To evaluate the epidemiological and morphological characteristics of coronary plaque in diabetic patients with symptomatic coronary heart disease (CHD) by dual-source computed tomography (DSCT). MATERIALS AND METHODS: From June 2013 to December 2014, 267 consecutive patients with type 2 diabetes mellitus were examined by DSCT. Plaque type, distribution, as well as extent and obstructive characteristics were determined for each segment. RESULTS: A total of 225 patients were included in the final study...
2017: Current Vascular Pharmacology
https://www.readbyqxmd.com/read/27619745/promising-but-still-a-matter-of-debate
#17
EDITORIAL
Yohei Sotomi, Patrick W Serruys
Several trials failed to demonstrate the efficacy of plaque modification device in patients with severely calcified coronary lesions. Safety and efficacy of the Diamondback 360® Coronary OAS have been demonstrated by the ORBIT II trial. The 2-year follow-up of the ORBIT II trial extends the favorable results previously shown at 30-day and 1-year follow-up. The single arm, non-randomized character of the trial with indirect historical comparison may restrict the results to hypothesis generating and entail further prospective randomized trials...
September 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27579325/coronary-plaque-characteristics-assessed-by-256-slice-coronary-ct-angiography-and-association-with-high-sensitivity-c-reactive-protein-in-symptomatic-patients-with-type-2-diabetes
#18
Jinling Zhang, Zhehao Lv, Deli Zhao, Lili Liu, Yong Wan, Tingting Fan, Huimin Li, Ying Guan, Bailu Liu, Qi Yang
Little is known regarding plaque distribution, composition, and the association with inflammation in type 2 diabetes mellitus (DM2). This study aimed to assess the relationship between coronary plaque subtypes and high-sensitivity C-reactive protein levels. Coronary CTA were performed in 98 symptomatic DM2 patients and 107 non-DM2 patients using a 256-slice CT. The extent and types of plaque as well as luminal narrowing were evaluated. Patients with DM2 were more likely to have significant stenosis (>50%) with calcified plaques in at least one coronary segment (p < 0...
2016: Journal of Diabetes Research
https://www.readbyqxmd.com/read/27544607/optical-coherence-tomography-assessment-of-incidence-morphological-characteristics-and-spontaneous-healing-course-of-edge-dissections-following-percutaneous-coronary-intervention-with-stent-implantation-in-patients-with-non-st-segment-elevation-myocardial-infarction
#19
Lisbeth Antonsen, Per Thayssen, Henrik Steen Hansen, Anders Junker, Karsten Tange Veien, Knud Nørregaard Hansen, Mikkel Hougaard, Lisette Okkels Jensen
BACKGROUND: Stenting-induced edge dissections (ED) can be assessed in detail by optical coherence tomography (OCT). This study sought to investigate the incidence, morphological characteristics, and spontaneous healing course of OCT-identified EDs following drug-eluting stent (DES) implantation in a non-ST segment elevation myocardial infarction (NSTEMI) patient-population. METHODS: Acute vessel wall injury at the 5-mm stent adjacent distal and proximal reference segments was assessed by post-procedure OCT and intravascular ultrasound (IVUS) in n=97 NSTEMI-patients (n=97 lesions)...
November 15, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27522574/prognostic-implications-of-coronary-ct-angiography-derived-quantitative-markers-for-the-prediction-of-major-adverse-cardiac-events
#20
Christian Tesche, Fabian Plank, Carlo N De Cecco, Taylor M Duguay, Moritz H Albrecht, Akos Varga-Szemes, Richard R Bayer, Junjie Yang, Isaac L Jacks, Bettina M Gramer, Ullrich Ebersberger, Ellen Hoffmann, Salvatore A Chiaramida, Gudrun Feuchtner, U Joseph Schoepf
OBJECTIVE: To evaluate quantitative markers derived from coronary CT angiography (coronary CTA) for the prediction of major adverse cardiac events (MACE). MATERIALS AND METHODS: Pooled data from two centers in the US and Europe were retrospectively analyzed. Forty-six patients (65.5 ± 8.1 years, 62% male) with suspected coronary artery disease (CAD) who had undergone dual-source CCTA and had experienced MACE within 12 months were included and compared to a Framingham risk score matched cohort (n = 46) without MACE...
November 2016: Journal of Cardiovascular Computed Tomography
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