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https://www.readbyqxmd.com/read/28196758/evaluation-of-image-quality-of-coronary-artery-plaque-with-rapid-kvp-switching-dual-energy-ct
#1
Yasutoshi Ohta, Shinichiro Kitao, Tomomi Watanabe, Junichi Kishimoto, Kazuhiro Yamamoto, Toshihide Ogawa
We evaluated the virtual monochromatic imaging (VMI) energy levels that maximize image quality of each coronary plaque component in dual-energy computed tomography angiography in 495 coronary segments (45 for each energy level). Maximal signal-to-noise ratios were different for plaque, lumen, fat, and surrounding tissue (p<0.05). Maximal contrast-to-noise ratios were observed at 70keV for calcified plaque (CP), non-calcified plaque (NCP), and fat in comparison with the lumen (p<0.05), and 70keV and 120keV for NCP in comparison with fat (p=0...
February 1, 2017: Clinical Imaging
https://www.readbyqxmd.com/read/28176255/partial-volume-correction-for-improved-pet-quantification-in-18-f-naf-imaging-of-atherosclerotic-plaques
#2
Jacobo Cal-Gonzalez, Xiang Li, Daniel Heber, Ivo Rausch, Stephen C Moore, Klaus Schäfers, Marcus Hacker, Thomas Beyer
BACKGROUND: Accurate quantification of plaque imaging using (18)F-NaF PET requires partial volume correction (PVC). METHODS: PVC of PET data was implemented by the use of a local projection (LP) method. LP-based PVC was evaluated with an image quality (NEMA) and with a thorax phantom with "plaque-type" lesions of 18-36 mL. The validated PVC method was then applied to a cohort of 17 patients, each with at least one plaque in the carotid or ascending aortic arteries...
February 7, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28169175/in%C3%A2-vivo-coronary-lesion-differentiation-with-computed-tomography-angiography-and-intravascular-ultrasound-as-compared-to-optical-coherence-tomography
#3
Wouter G Wieringa, Chris P H Lexis, Erik Lipsic, Hindrik W van der Werf, Johannes G M Burgerhof, Vincent E Hagens, G Louis Bartels, Alexander Broersen, Remco A Schurer, Eng-Shiong Tan, Pim van der Harst, Ad F M van den Heuvel, Tineke P Willems, Gabija Pundziute
BACKGROUND: In vitro studies have shown the feasibility of coronary lesion grading with computed tomography angiography (CTA), intravascular ultrasound (IVUS) and optical coherence tomography (OCT) as compared to histology, whereas OCT had the highest discriminatory capacity. OBJECTIVE: We investigated the ability of CTA and IVUS to differentiate between early and advanced coronary lesions in vivo, OCT serving as standard of reference. METHODS: Multimodality imaging was prospectively performed in 30 NSTEMI patients...
January 22, 2017: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/28150055/numerical-modeling-of-nitinol-stent-oversizing-in-arteries-with-clinically-relevant-levels-of-peripheral-arterial-disease-the-influence-of-plaque-type-on-the-outcomes-of-endovascular-therapy
#4
Can Gökgöl, Nicolas Diehm, Philippe Büchler
Oversizing of the Nitinol stents in the femoro-popliteal arterial tract is commonly performed by clinicians and further encouraged by stent manufacturers. However, in spite of the procedure's supposed benefits of strong wall apposition and increased luminal gain, its effects on the mechanical behavior of arteries with peripheral arterial disease are not fully clear. In this study, finite element (FE) analyses of endovascular revascularization of an idealized artery with 70% stenosis and three different plaque types have been performed to examine the influence of Nitinol stent oversizing on the arterial stresses and acute lumen gain...
February 1, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28110570/-computer-tomography-examination-of-the-coronary-system-national-plaque-registry-and-database-hungary
#5
Zsolt Bagyura, Márton Kolossváry, Béla Merkely, Pál Maurovich-Horvat
INTRODUCTION AND AIM: Coronary computer tomography angiography is a unique non-invasive imaging technique with the capability to provide information regarding plaque quantity, burden and structure. A reliable registry is required to use the data of these examinations in research projects. The difficulty is that registries need double data entry simultaneously to the hospital information system. METHOD: Our registry solves this problem through a structured reporting tool, which generates clinical report and stores all data simultaneously...
January 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28065380/iterative-model-reconstruction-reduces-calcified-plaque-volume-in-coronary-ct-angiography
#6
Mihály Károlyi, Bálint Szilveszter, Márton Kolossváry, Richard A P Takx, Csilla Celeng, Andrea Bartykowszki, Ádám L Jermendy, Alexisz Panajotu, Júlia Karády, Rolf Raaijmakers, Walter Giepmans, Béla Merkely, Pál Maurovich-Horvat
OBJECTIVE: To assess the impact of iterative model reconstruction (IMR) on calcified plaque quantification as compared to filtered back projection reconstruction (FBP) and hybrid iterative reconstruction (HIR) in coronary computed tomography angiography (CTA). METHODS: Raw image data of 52 patients who underwent 256-slice CTA were reconstructed with IMR, HIR and FBP. We evaluated qualitative, quantitative image quality parameters and quantified calcified and partially calcified plaque volumes using automated software...
February 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28052860/increased-prevalence-of-coronary-plaque-in-patients-with-psoriatic-arthritis-without-prior-diagnosis-of-coronary-artery-disease
#7
Jiayun Shen, Ka-Tak Wong, Isaac T Cheng, Qing Shang, Edmund K Li, Priscilla Wong, Emily W Kun, Mei Yan Law, Ronald Yip, Isaac Yim, Shirley Ying, Martin Li, Tena K Li, Chun-Kwok Wong, Tracy Y Zhu, Jack Jock-Wai Lee, Mimi Chang, Alex Pui-Wai Lee, Lai-Shan Tam
OBJECTIVES: To evaluate coronary atherosclerosis in patients with psoriatic arthritis (PsA) and control subjects using coronary CT angiography (CCTA). METHODS: Ninety consecutive patients with PsA (male: 56(62.2%); 50.3±11.1 years) were recruited. 240 controls (male: 137(57.1%); 49.6±10.7 years) without known cardiovascular (CV) diseases who underwent CCTA due to chest pain and/or multiple CV risk factors were recruited for comparison. RESULTS: Patients with PsA and controls were matched in age, gender and traditional CV risk factors (all p>0...
January 4, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28048223/we-fg-207b-06-plaque-composition-measurement-with-dual-energy-computed-tomography
#8
C Wang, H Ding, S Malkasian, S Molloi
PURPOSE: To investigate the feasibility of characterizing arterial plaque composition in terms of water, lipid and protein or calcium using dual energy computed tomography. Characterization of plaque composition can potentially help distinguish vulnerable from stable plaques. METHODS: Simulations studies were performed by the CT simulator based on ASTRA tomography toolbox. The beam energy for dual energy images was selected to be 80 kVp and 135 kVp. The radiation dose and energy spectrum for the CT simulator were carefully calibrated with respect to a 320-slice CT scanner...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28025263/quantitative-plaque-features-from-coronary-computed-tomography-angiography-to-identify-regional-ischemia-by-myocardial-perfusion-imaging
#9
Mariana Diaz-Zamudio, Tobias A Fuchs, Piotr Slomka, Yuka Otaki, Reza Arsanjani, Heidi Gransar, Guido Germano, Daniel S Berman, Philipp A Kaufmann, Damini Dey
AIMS: We aimed to investigate whether quantitative plaque features measured from coronary CT angiography (CCTA) predict ischemia by myocardial perfusion SPECT imaging (MPI). METHODS AND RESULTS: Hundred and eighty-four consecutive patients (63% males) with suspected-coronary artery disease, undergoing hybrid CCTA, and attenuation corrected solid state (99m)Tc stress/rest MPI and single vessel ischemia were considered. Quantitative analysis of CCTA derived non-calcified plaque (NCP), low-density NCP [< 30 Hounsfield Units (HU)] (LDNCP), calcified and total plaque burdens (%, normalized to vessel volume), maximum diameter stenosis and contrast density difference (CD, maximum difference in HU/lumen area within lesion)...
December 26, 2016: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/27993385/association-of-tobacco-use-and-cessation-with-coronary-atherosclerosis
#10
Michael K Cheezum, Alexander Kim, Marcio S Bittencourt, David Kassop, Alexander Nissen, Dustin M Thomas, Binh Nguyen, Robert J Glynn, Nishant R Shah, Todd C Villines
BACKGROUND AND AIMS: The impact of tobacco use and cessation on atherogenesis remains unclear. We aimed to study the association of tobacco use and prior cessation with the presence, extent and severity of atherosclerosis on coronary computed tomographic angiography (CTA). METHODS: We examined 1798 consecutive symptomatic patients without known coronary artery disease (CAD) referred for CTA, stratified by smoking status (never, current [within 30 days], or former [>30 days before CTA])...
November 16, 2016: Atherosclerosis
https://www.readbyqxmd.com/read/27973332/limitations-of-oct-in-identifying-and-quantifying-lipid-components-an-in-vivo-comparison-study-with-ivus-nirs
#11
Luca Di Vito, Fabrizio Imola, Laura Gatto, Enrico Romagnoli, Ugo Limbruno, Valeria Marco, Andrea Picchi, Antonio Micari, Mario Albertucci, Francesco Prati
AIMS: We assessed the agreement between IVUS-NIRS and OCT to assess lipid plaques in patients with acute coronary syndromes or stable angina. In addition, the impact of both macrophages and calcifications was investigated. METHODS AND RESULTS: Forty-three patients undergoing both IVUS-NIRS and OCT assessment of the culprit and/or non culprit coronary lesions were enrolled. Cross-sections from lipid plaques, calcified plaques and normal appearing vessel tracts were identified and matched with the two imaging techniques...
December 15, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27899854/association-of-neutrophil-to-lymphocyte-ratio-with-the-severity-and-morphology-of-coronary-atherosclerotic-plaques-detected-by-multidetector-computerized-tomography
#12
Ahmet Hakan Ateş, Kudret Aytemir, Duygu Koçyiğit, Muhammed Ulvi Yalcin, Kadri Murat Gürses, Hikmet Yorgun, Uğur Canpolat, Tuncay Hazırolan, Necla Özer
BACKGROUND: Studies have demonstrated a consistent relationship between white blood cell (WBC) counts and coronary artery disease (CAD). The neutrophil/lymphocyte ratio (NLR) has been considered as a potential marker for identifying individuals under risk of CAD and associated events. In this study, we aimed to evaluate whether NLR was associated with the severity and morphology of coronary atherosclerotic plaques shown by multidetector computed tomography (MDCT). METHODS: Our study population consisted of 684 patients who underwent dual-source 64 slice MDCT for the assessment of CAD...
November 2016: Acta Cardiologica Sinica
https://www.readbyqxmd.com/read/27835741/plaque-progression-assessed-by-a-novel-semi-automated-quantitative-plaque-software-on-coronary-computed-tomography-angiography-between-diabetes-and-non-diabetes-patients-a-propensity-score-matching-study
#13
Rine Nakanishi, Indre Ceponiene, Kazuhiro Osawa, Yanting Luo, Mitsuru Kanisawa, Nichelle Megowan, Negin Nezarat, Sina Rahmani, Alexander Broersen, Pieter H Kitslaar, Christopher Dailing, Matthew J Budoff
BACKGROUND AND AIMS: We aimed at investigating whether diabetes is associated with progression in coronary plaque components. METHODS: We identified 142 study subjects undergoing serial coronary computed tomography angiography. The resulting propensity score was applied 1:1 to match diabetic patients to non-diabetic patients for clinical risk factors, prior coronary stenting, coronary artery calcium (CAC) score and the serial scan interval, resulting in the 71 diabetes and 71 non-diabetes patients...
December 2016: Atherosclerosis
https://www.readbyqxmd.com/read/27824692/long-term-marathon-running-is-associated-with-low-coronary-plaque-formation-in-women
#14
William O Roberts, Robert S Schwartz, Stacia Merkel Kraus, Jonathan G Schwartz, Gretchen Peichel, Ross F Garberich, John R Lesser, Stephen N Oesterle, Kelly K Wickstrom, Thomas Knickelbine, Kevin M Harris
INTRODUCTION: Marathon running is presumed to improve cardiovascular risk, but health benefits of high volume running are unknown. High resolution coronary computed tomography angiography (CCTA) and a cardiac risk factor assessment were completed in women with long term marathon running histories to compare to sedentary women with similar risk factors. METHODS: Women who had run at least one marathon per year for 10-25 years underwent CCTA, 12-lead ECG, blood pressure and heart rate measurement, lipid panel, and a demographic/health risk factor survey...
November 7, 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/27738787/integrated-non-invasive-approach-to-atherosclerosis-with-cardiac-ct-and-carotid-ultrasound-in-patients-with-suspected-coronary-artery-disease
#15
Ludovico La Grutta, Marta Marasà, Patrizia Toia, Daniele Ajello, Domenico Albano, Erica Maffei, Emanuele Grassedonio, Giuseppina Novo, Massimo Galia, Giuseppe Caruso, Salvatore Novo, Filippo Cademartiri, Massimo Midiri
OBJECTIVE: The aim of the study was to compare the atherosclerotic disease in the coronary and carotid arteries in patients who underwent non-invasive imaging for suspected stable coronary artery disease (CAD). MATERIALS AND METHODS: 107 patients (64 men, age 59 ± 12) with atypical chest pain underwent cardiac CT (CCT) and carotid ultrasound (US) on the same day. Severity (obstructive or not-obstructive disease), location, shape, and composition of atherosclerotic plaques in the two districts were evaluated...
January 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/27733980/comparison-of-coronary-plaque-coronary-artery-calcification-and-major-adverse-cardiac-events-in-chinese-outpatients-with-and-without-type-2-diabetes
#16
Lijie Zhu, Jingjing Liu, Chuanyu Gao, Wenli Zhao, Jing Que, Xianpei Wang, Datun Qi, Jun Liu, Wentao Xiao, Juanjuan Yan, Wentao Li, You Zhang, Honghui Yang
OBJECTIVE: Diabetes substantially increases the risk of cardiovascular disease (CAD) and is associated with an increased risk of CAD mortality. The purpose of this study was to investigate the differences in coronary artery plaque, coronary artery calcification (CAC) measured in outpatients with and without type 2 diabetes, and the occurrence rate of a major adverse cardiac event (MACE) throughout follow-up with the same patients. METHODS: Five hundred eighty-eight outpatients with suspected CAD comprising 208 diabetic and 380 non-diabetic patients were enrolled in this study...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27733727/epicardial-adipose-tissue-as-a-predictor-for-the-development-of-non-calcified-coronary-plaque
#17
Koichi Kaikita
No abstract text is available yet for this article.
October 12, 2016: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/27721862/association-of-neutrophil-lymphocyte-ratio-with-plaque-morphology-in-patients-with-asymptomatic-intermediate-carotid-artery-stenosis
#18
İsa Öner Yüksel, Erkan Köklü, Şakir Arslan, Göksel Çağırcı, Eylem Özaydın Göksu, Pınar Koç, Serkan Çay, Filiz Kızılırmak
BACKGROUND AND OBJECTIVES: Non-calcified carotid plaques are more unstable than calcified plaques, and they are associated with a higher risk of rupture, thromboembolism, and consequently, stroke. The purpose of the present study is to compare calcified and non-calcified plaques that cause intermediate carotid artery stenosis with respect to neutrophil/lymphocyte ratio (NLR). SUBJECTS AND METHODS: A total number of 139 asymptomatic patients with 50-70% stenosis of the carotid artery were included in this study...
September 2016: Korean Circulation Journal
https://www.readbyqxmd.com/read/27714714/evaluation-of-mean-platelet-volume-and-platelet-distribution-width-in-patients-with-asymptomatic-intermediate-carotid-artery-plaque
#19
Fatih Yılmaz, Erkan Köklü, Filiz Kizilirmak Yilmaz, Elif Sarıönder Gencer, Ahmet Şükrü Alparslan, Özlem Yıldırımtürk
BACKGROUND: Platelets play a significant role in the pathogenesis of atherosclerosis. In atherosclerotic plaques, the risk of plaque rupture is more crucial than the severity of the stenosis they cause. Non-calcified carotid artery plaques are more unstable than calcified plaques, and they are associated with a higher risk of rupture, thromboembolism, and consequently, stroke. AIM: The purpose of the present study is to compare calcified and non-calcified plaques that cause intermediate carotid artery stenosis, with respect to mean platelet volume (MPV) and platelet distribution width (PDW)...
2017: Kardiologia Polska
https://www.readbyqxmd.com/read/27677761/national-trends-among-radiologists-in-reporting-coronary-artery-calcium-in-non-gated-chest-computed-tomography
#20
Jacobo Kirsch, Felipe Martinez, David Lopez, Gian M Novaro, Craig R Asher
Coronary artery calcification (CAC) is a known risk factor for adverse outcomes in the general population and in patients with coronary artery disease. We performed a survey of United States radiologists to evaluate the trends in reporting the presence or absence of CAC on NCCT examinations. An 11 multiple-choice questionnaire was distributed to members of the American College of Radiology, and 530 members participated in the study. Eighty-seven percent of the analyzed group report the presence of CAC on standard CT scans of the chest, and approximately half them (52 %) use a qualitative modifier...
September 27, 2016: International Journal of Cardiovascular Imaging
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