Jeff M Smit, Silvia Rocchiccioli, Giovanni Signore, Elena Michelucci, Nicoletta Di Giorgi, Alexander R van Rosendael, Mohammed El Mahdiui, Danilo Neglia, Juhani Knuuti, Antti Saraste, Ronny R Buechel, Anna Teresinska, Maria N Pizzi, Albert Roque, Rosa Poddighe, Bart J Mertens, Chiara Caselli, Oberdan Parodi, Gualtiero Pelosi, Arthur J Scholte
AIMS: To date, no studies have investigated the association between lipid species and coronary plaque changes over time, quantitatively assessed by serial imaging. We aimed to prospectively determine the association between lipid species quantified by plasma lipidomic analysis, with coronary plaque changes according to composition assessed by quantitative serial analysis of coronary computed tomography angiography (CTA). METHODS AND RESULTS: Patients with suspected coronary artery disease (CAD) undergoing baseline coronary CTA were prospectively enrolled by 7 EU Centers in the SMARTool study and submitted to clinical, molecular and coronary CTA re-evaluation at follow-up (interscan period 6...
March 6, 2024: European Heart Journal Cardiovascular Imaging