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paranasal sinus cancer

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https://www.readbyqxmd.com/read/29909683/metastatic-endometrial-cancer-of-the-paranasal-sinuses
#1
A Bashyam, A Stewart, K Potter, I Bagwan, V S Sunkaraneni
Endometrial carcinoma is the fourth most common cancer affecting women in the UK. Its most frequent sites of spread are to the pelvic and para-aortic lymph nodes, vagina and peritoneum. We report a case of a 63-year-old woman with known endometrial cancer who presented with left facial swelling and eye displacement. Investigations revealed an expansile soft-tissue density mass arising within the bone, centred on the left zygoma, with exophytic extension into the left maxillary antrum, infratemporal fossa and inferiorly into the orbit...
June 18, 2018: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/29863554/surgical-treatment-of-maxillary-antrum-neoplasms
#2
Elham Hazeim Abdulkareem, Kamal Turki Aftan
Paranasal sinus cancers comprise about 0.3% of all cancers and 80% of these lesions arise in the maxillary sinus. A masquerading primary sinus tumour represents a therapeutic challenge as most patients with maxillary antrum cancer are diagnosed with advanced disease. However, distant metastases rarely occur. We examined the clinical outcome of patients with antrum neoplasms. Medical records were obtained for all patients diagnosed with a sinus malignancy between July 2009 and January 2014. During this period, 41 patients with maxillary tumours were treated, among which 9 patients received a maxillectomy...
May 31, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29755916/a-case-of-sinonasal-undifferentiated-carcinoma-with-brain-metastases
#3
Julianna Sienna, Nhu-Tram Nguyen, Julie Arsenault, Ian Hodson, Brandon Meyers
Sinonasal undifferentiated carcinoma (SNUC) is a rare aggressive neoplasm arising in the nasal cavity and paranasal sinuses. We report a unique case of an 80-year-old man who presented with a locally advanced SNUC involving the ethmoid, sphenoid, and maxillary sinuses and bilateral lymph nodes, clinical T4N2M0. Given his age and the initial extent of his primary tumour, he was treated with neoadjuvant chemotherapy followed by chemoradiation with a split course of 50 Gray (Gy) in 40 fractions delivered twice a day...
March 13, 2018: Curēus
https://www.readbyqxmd.com/read/29626308/patterns-of-treatment-failure-in-patients-with-sinonasal-mucosal-melanoma
#4
Moran Amit, Samantha Tam, Ahmed S Abdelmeguid, Michael E Kupferman, Shirley Y Su, Shaan M Raza, Franco DeMonte, Ehab Y Hanna
BACKGROUND: Head and neck mucosal melanoma is a locally aggressive tumor with a high recurrence rate. The paranasal sinuses and nasal cavity are the most common primary tumor sites. OBJECTIVE: The purpose of this retrospective study was to identify independent predictors of outcome in sinonasal mucosal melanoma (SNMM) and characterize the patterns of treatment failure. METHODS: This study included 198 patients with SNMM who had been treated at The University of Texas MD Anderson Cancer Center from 1 January 1991 through 31 December 2016...
June 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29607722/ethmoidal-metastasis-as-a-first-presentation-of-breast-cancer-a-case-report
#5
A Maity, E Maughan, S Vasani, G Alusi
Distant metastasis in advanced breast cancer is not uncommon; however, spread to the paranasal sinuses is extremely rare. We present a case of a woman who presented to our ophthalmology colleagues with worsening unilateral proptosis secondary to a tumour mass within her ethmoid sinuses. Biopsy of the ethmoid tumour showed adenocarcinoma of unknown origin. Whole-body positron emission computed tomography demonstrated a breast primary lesion. The patient was treated with palliative chemotherapy, and the patient remains well at this point...
April 1, 2018: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/29602585/trend-in-otolaryngological-surgeries-in-an-era-of-super-aging-descriptive-statistics-using-a-japanese-inpatient-database
#6
Sayaka Suzuki, Hideo Yasunaga, Hiroki Matsui, Kiyohide Fushimi, Tatsuya Yamasoba
OBJECTIVE: To reveal the age distribution and capture the longitudinal trend in otolaryngological surgeries performed in Japan, where society is rapidly aging. METHODS: Using the Diagnosis Procedure Combination database, we extracted data on patients who were hospitalized and underwent any type of otolaryngological surgery in departments of otolaryngology or head and neck surgery from fiscal year 2007 to fiscal year 2013. Type of surgery, patient's age, and fiscal year were compared...
March 27, 2018: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29559870/the-submental-island-flap-is-a-viable-reconstructive-option-for-a-variety-of-head-and-neck-ablative-defects
#7
Blair M Barton, Charles A Riley, Jason D Pou, Christian P Hasney, Brian A Moore
Background: The submental island flap (SIF) is a pedicled flap based upon the submental artery and vein. Its utility in reconstruction following ablative head and neck procedures has been applied to various subsites including skin, lip, buccal mucosa, retromolar trigone, parotidectomy defects, and tongue. We review our experience using the SIF for reconstruction following tumor ablation. Methods: This prospective case series with medical record review includes consecutive patients undergoing SIF reconstruction following ablative surgery for malignancy at a single tertiary care facility between November 2014 and November 2016...
2018: Ochsner Journal
https://www.readbyqxmd.com/read/29541239/-prr4-a-novel-downregulated-gene-in-laryngeal-cancer
#8
Seda Ekizoglu, Turgut Ulutin, Jalal Guliyev, Nur Buyru
Head and neck squamous cell carcinomas (HNSCC) are a diverse group of tumor types, including neoplasia of the paranasal sinuses, oral cavity, trachea, pharynx and larynx. Laryngeal cancer is the most common type of HNSCC. The proline-rich 4 (PRR4) protein is synthesized in the acinar cells of human lacrimal glands. Previous studies have demonstrated that PRR4 may function as an antimicrobial protein protecting the ocular surface and the oral cavity. In order to determine differentially expressed genes (DEGs) in laryngeal tumors, a GeneFishing Assay was performed; 27 DEGs were identified...
April 2018: Oncology Letters
https://www.readbyqxmd.com/read/29510615/paranasal-sinus-invasion-in-nasopharyngeal-carcinoma-after-intensity-modulated-radiotherapy
#9
Caineng Cao, Feng Jiang, Qifeng Jin, Ting Jin, Shuang Huang, Qiaoying Hu, Yuanyuan Chen, Yongfeng Piao, Yonghong Hua, Xinglai Feng, Xiaozhong Chen
Purpose: The aim of this study is to evaluate the prognostic significance of paranasal sinus invasion for nasopharyngeal carcinoma (NPC) and its suitable position in the T classification. Materials and Methods: The magnetic resonance imaging (MRI) scans of 695 patients with previously untreated, biopsy-proven, non-metastatic NPC that was treated with intensity-modulated radiotherapy (IMRT) were reviewed retrospectively. Results: The incidence of paranasal sinus invasion was 39...
February 26, 2018: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/29423230/review-of-carcinogenicity-of-hexavalent-chrome-and-proposal-of-revising-approval-standards-for-an-occupational-cancers-in-korea
#10
Jungwon Kim, Sangyun Seo, Yangho Kim, Dae Hwan Kim
Background: The objective of this study is to suggest revised recognition standards for occupational disease due to chromium (VI) by reflecting recent domestic and international research works and considering domestic exposure status with respect to target organs, exposure period, and cumulative exposure dose in relation to the chromium (VI)-induced occupational disease compensation. Methods: In this study, the reports published by major international institutions such as World Health Organization (WHO) International Agency for Research on Cancer (IARC) (2012), Occupational Safety and Health Administration (OSHA) (2006), National Institute for Occupational Safety and Health (NIOSH) (2013), American Conference of Governmental Industrial Hygienists (ACGIH) (2004), National Toxicology Program (NTP) (2014), and Agency for Toxic Substances and Disease Registry (ASTDR) (2012) were reviewed and the recent research works searched by PubMed were summarized...
2018: Annals of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29382992/osteosarcomas-of-the-head-and-neck-region-a-case-series-with-a-review-of-literature
#11
Arvind Krishnamurthy, Ravishankar Palaniappan
Background: Osteosarcomas of head and neck region have unique biology and exhibit a clinical behavior and natural history that is distinct from osteosarcomas of the trunk and extremities. Our understanding of this malignant bone tumor is largely based on data from single institutions or compiled from registries, and hence the clinical practice guidelines seem confusing and conflicting. Aims and Objectives: To analyze the demographic profile, disease characteristics and survival outcomes of osteosarcoma of head and neck region...
March 2018: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/29381961/rare-metastasis-to-paranasal-sinuses-from-triple-negative-breast-cancer-a-case-report-and-literature-review
#12
Jie Xiong, Jing Chen, Liduan Zheng, Shengli Yang, Guifang Zhao, Jing Cheng
RATIONALE: Breast cancer, the most common form of cancer among women, rarely metastases to the head and neck region. To date, there have been only 6 similar cases in the literature, and most patients in these reports had very poor prognosis. PATIENTS CONCERNS: We report a 61-year-old female presented pain and numbness on the right side of the face 5 years after being diagnosed with triple-negative breast cancer. DIAGNOSIS: Magnetic resonance imaging (MRI) revealed a tissue mass in the sphenoid sinus...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29371736/small-cell-neuroendocrine-carcinoma-of-nose-and-paranasal-sinuses-the-shaukat-khanum-memorial-cancer-hospital-experience-and-review-of-literature
#13
Muhammad Faisal, Irfan Haider, Mohammad Adeel, Omer Waqas, Raza Hussain, Arif Jamshed
Small cell neuroendocrine carcinoma (SCNEC) is a rare disease of nose and paranasal sinuses. In contrast to other regions SCNEC of this region has been reported to be recurrent and locally aggressive. No definite treatment has been established till date because of rarity of this disease. The purpose of this descriptive study is to present the series of 8 cases with SNEC of nose and paranasal sinuses. Retrospective review of 8 patients presenting with Small cell neuroendocrine carcinoma of nose and paranasal sinuses, from January, 2005 to December, 2014 treated at Shaukat Khanum Memorial Cancer Hospital & Research Centre, Lahore was performed to determine the clinical characteristics and outcome of this disease...
January 2018: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/29173756/proton-therapy-for-head-and-neck-cancers
#14
REVIEW
Pierre Blanchard, Gary Brandon Gunn, Alexander Lin, Robert L Foote, Nancy Y Lee, Steven J Frank
Because of its sharp lateral penumbra and steep distal fall-off, proton therapy offers dosimetric advantages over photon therapy. In head and neck cancer, proton therapy has been used for decades in the treatment of skull-base tumors. In recent years the use of proton therapy has been extended to numerous other disease sites, including nasopharynx, oropharynx, nasal cavity and paranasal sinuses, periorbital tumors, skin, and salivary gland, or to reirradiation. The aim of this review is to present the physical properties and dosimetric benefit of proton therapy over advanced photon therapy; to summarize the clinical benefit described for each disease site; and to discuss issues of patient selection and cost-effectiveness...
January 2018: Seminars in Radiation Oncology
https://www.readbyqxmd.com/read/29134827/serum-plasma-and-saliva-biomarkers-for-head-and-neck-cancer
#15
Lidia Maria Rebolho Batista Arantes, Ana Carolina De Carvalho, Matias Eliseo Melendez, André Lopes Carvalho
Head and neck squamous cell carcinoma (HNSCC) encompasses tumors arising from several locations (oral and nasal cavities, paranasal sinuses, salivary glands, pharynx, and larynx) and currently stands as the sixth most common cancer worldwide. The most important risk factors identified so far are tobacco and alcohol consumption, and, for a subgroup of HNSCCs, infection with high-risk types of human papillomavirus (HPV). Despite several improvements in the treatment of these tumors in the last decades, overall survival rates have only improved marginally, mainly due to the advanced clinical stage at diagnosis and the high rates of treatment failure associated with this late diagnosis...
January 2018: Expert Review of Molecular Diagnostics
https://www.readbyqxmd.com/read/29045018/patient-disease-and-treatment-factors-associated-with-overall-survival-in-esthesioneuroblastoma
#16
Ryan M Carey, Joseph Godovchik, Alan D Workman, Edward C Kuan, Arjun K Parasher, Jinbo Chen, James N Palmer, Nithin D Adappa, Jason G Newman, Jason A Brant
BACKGROUND: Esthesioneuroblastomas (ENB) are uncommon and data regarding outcomes are often limited to single-institution series. The National Cancer Database (NCDB), which contains outcomes information from treatment centers across the United States, represents an opportunity to evaluate outcomes for rare diseases such as ENB across multiple institutions. METHODS: The NCDB was queried for location codes corresponding to the nasal cavity and paranasal sinuses and the histology code for ENB...
December 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29044491/approaches-to-regional-lymph-node-metastasis-in-patients-with-head-and-neck-mucosal-melanoma
#17
Moran Amit, Samantha Tam, Ahmed S Abdelmeguid, Dianna B Roberts, Shaan M Raza, Shirley Y Su, Michael E Kupferman, Franco DeMonte, Ehab Y Hanna
BACKGROUND: Mucosal melanomas in the head and neck region are most often located in the nasal cavity and paranasal sinuses. To the authors' knowledge, the prognostic effects of lymph node metastasis in patients with sinonasal mucosal melanoma (SNMM) have not been established. Therefore, the objective of the current study was to determine the effects of lymph node metastasis on survival. METHODS: The current study included 198 patients with SNMM who had been treated between 1985 and 2016 at The University of Texas MD Anderson Cancer Center in Houston...
February 1, 2018: Cancer
https://www.readbyqxmd.com/read/28939074/predictors-of-survival-in-head-and-neck-mucosal-melanoma
#18
Matthew Q Schmidt, John David, Emi J Yoshida, Kevin Scher, Alain Mita, Stephen L Shiao, Allen S Ho, Zachary S Zumsteg
OBJECTIVES: To evaluate hospital-based data of head and neck mucosal melanoma patients in order to identify predictors of survival. MATERIALS AND METHODS: The National Cancer Data Base was used to identify 1368 patients with head and neck mucosal melanoma diagnosed between the years of 2004 and 2012. The Kaplan-Meier method was utilized to estimate overall survival, and multivariate Cox regression analyses were performed to assess the impact of covariates on survival after adjusting for confounding variables...
October 2017: Oral Oncology
https://www.readbyqxmd.com/read/28815617/disparities-in-sinonasal-squamous-cell-carcinoma-short-and-long-term-outcomes-analysis-from-the-national-cancer-database
#19
Ryan M Carey, Arjun K Parasher, Alan D Workman, Carol H Yan, Jordan T Glicksman, Jinbo Chen, James N Palmer, Nithin D Adappa, Jason G Newman, Jason A Brant
OBJECTIVES/HYPOTHESIS: To examine sociodemographic, hospital-specific, and disease-related characteristics in relation to outcomes in sinonasal squamous cell carcinoma (SCC). STUDY DESIGN: The National Cancer Database was queried for location codes corresponding to the nasal cavity and paranasal sinuses and histology codes representing SCC malignancy. Multivariate analyses were performed against short- and long-term outcomes (overall survival, days to discharge, 30-day readmission, and 30- and 90-day mortality)...
March 2018: Laryngoscope
https://www.readbyqxmd.com/read/28790865/survivorship-of-patients-with-head-and-neck-cancer-receiving-care-in-a-tertiary-health-facility-in-nigeria
#20
Vitalis C Okwor, Adeniyi F Fagbamigbe, Olufunmilayo I Fawole
BACKGROUND: Head and neck cancer (HNC) is a major clinical and public health concern worldwide which impairs the vital functions of life. The treatment of metastatic HNCs is mainly palliative. This study examined the survival patterns and treatment outcomes in patients with HNCs in a tertiary hospital in Nigeria. MATERIALS AND METHODS: A review of the case files and treatment cards of patients with histological diagnosis of HNCs seen between January 2002 and December 2011 at the Radiotherapy Department, University College Hospital, Ibadan, was conducted...
2017: Cancer Management and Research
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