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https://www.readbyqxmd.com/read/28103413/parental-orders-and-the-rights-of-surrogate-mothers
#1
Nathan Hodson, Susan Bewley
Obstetricians need to be aware of potential legal changes which may impact the doctor-patient relationship in surrogacy cases. Presently, English law recognises the surrogate as the mother. After giving birth, she may hand over the baby. The commissioning couple then apply for Parental Orders and become legal parents if the conditions in the Surrogacy Arrangements Act 1985 are met. This article is protected by copyright. All rights reserved.
January 19, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28101779/randomized-controlled-trial-of-topical-emla-and-vapocoolant-spray-for-reducing-pain-during-wdpt-vaccination
#2
Navratan Kumar Gupta, Amit Upadhyay, Ajeet Kumar Dwivedi, Astha Agarwal, Vijay Jaiswal, Abhishek Singh
BACKGROUND: Intramuscular vaccination is among the most common source of iatrogenic pain in infants. Vapocoolant sprays are rapid-acting alternative to topical anesthetics. They provide transient anesthesia via evaporation induced skin cooling, and reduce pain due to vaccine injection in children and adults. The objective was to compare the synergistic analgesic effect of eutectic mixture of local anesthetics (EMLA) with breastfeeding (EB group) and vapocoolant spay with breastfeeding (VB group) to that of only breastfeeding (BO group) during whole cell diptheria, pertussis and tetanus (wDPT) vaccination...
January 19, 2017: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/28101619/-all-rounder-vitamin%C3%A2-d
#3
S Unholzer, A Rothmund, E Haen
BACKGROUND: Many indications are discussed for vitamin D substitution, such as osteoporosis, autoimmune diseases, cancer and psychiatric diseases. Also discussed is the fact that the majority of the German population suffer from a vitamin D deficiency. OBJECTIVE: Review of the study results for these individual diseases and a critical analysis of the currently established therapeutic reference range, which defines a vitamin D deficiency. MATERIAL AND METHODS: A literature search was carried out in the statements of the German Society for Nutrition, in scientific publications and journals...
January 18, 2017: Der Nervenarzt
https://www.readbyqxmd.com/read/28101502/pregnant-woman-with-atypical-hemolytic-uremic-syndrome-delivered-a-healthy-newborn-under-eculizumab-treatment
#4
Erol Demir, Halil Yazici, Yasemin Ozluk, Isin Kilicaslan, Aydin Turkmen
Pregnancy-associated thrombotic microangiopathy is a very rare condition; however, it significantly increases fetal or maternal morbidity and mortality. Pregnancy may trigger atypical hemolytic uremic syndrome (aHUS) or thrombotic thrombocytopenic purpura. The risk for pregnancy-associated aHUS is highest during the second pregnancy. The outcome is usually poor with 50-60% mortality; renal dysfunction and hypertension are the rule in those who survive the acute episode. After the development of complement regulation mechanisms and aHUS pathogenesis, eculizumab has been widely used as a first-line treatment in aHUS...
September 2016: Case Reports in Nephrology and Dialysis
https://www.readbyqxmd.com/read/28101432/atypical-hemolytic-uremic-syndrome-in-first-trimester-pregnancy-successfully-treated-with-eculizumab
#5
Gabriela Andries, Michael Karass, Srikanth Yandrapalli, Katherine Linder, Delong Liu, John Nelson, Rahul Pawar, Savneek Chugh
BACKGROUND: Atypical hemolytic uremic syndrome is a rare disorder which is known to cause acute thrombotic microangiopathy during pregnancy with poor maternal and fetal outcomes. Atypical hemolytic uremic syndrome is caused mostly by dysregulation of alternative complement pathway secondary to genetic mutations. Most of the cases reported have been in the post-partum period. We report a rare case of a patient who presents with thrombotic microangiopathy in the first trimester of her eleventh pregnancy and was successfully treated with eculizumab...
2017: Experimental Hematology & Oncology
https://www.readbyqxmd.com/read/28101156/clinical-and-microbiological-profile-of-babies-born-with-risk-of-neonatal-sepsis
#6
Bin Zhou, Xiao Liu, Jie-Bin Wu, Bao Jin, Yan-Yan Zhang
The aim of the present study was to evaluate the effects of antibiotics on the condition of babies born with risk of neonatal sepsis. From March, 2014 to February, 2015, 200 neonates born with risk factors of septicemia in the Neonatal Intensive Care Unit at Xuzhou Central Hospital, were enrolled in the present study. Venous blood samples were collected within 6 h of birth using aseptic technique. Part of the blood specimens were cultured using BACTEC PEDS PLUS/F Culture Vials. Subsequently, the subcultures were prepared from each presumptive positive vial and bacterial isolates were identified...
December 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28101037/successful-restoration-of-visual-acuity-with-an-extended-range-of-vision-intraocular-lens-after-multifocal-laser-ablation
#7
Sondra Black
As our baby boomer population is aging and developing cataracts, so are our post-LASIK patients. These patients underwent LASIK surgery as they wished to be spectacle-free and are hoping to remain so after intraocular lens (IOL) surgery. Unfortunately, very little information is available regarding the suitability of presbyopia correcting IOLs for post-LASIK patients. This case represents successful implantation of an extended range of vision IOL in a 59-year-old patient who underwent multifocal ablation excimer laser surgery 12 years before...
September 2016: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28100569/multiple-pregnancy-in-a-primigravida-with-uncorrected-pentalogy-of-fallot
#8
Pamela Partana, Jarrod Kah Hwee Tan, Ju Le Tan, Lay Kok Tan
Pentalogy of Fallot is a cyanotic congenital heart disease that has guarded prognosis without surgical intervention in infancy. Women with uncorrected defects rarely survive into childbearing age and pregnancy in this group is associated with a high rate of perinatal loss. Physiological cardiovascular changes in pregnancy can lead to maternal haemodynamic instability with subsequent adverse cardiac sequelae with or without fetal decompensation. Optimum management and pregnancy outcomes in mother with uncorrected Pentalogy of Fallot and twin pregnancy have not been described in the literature...
January 18, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28100563/effect-of-socioeconomic-disadvantage-remoteness-and-indigenous-status-on-hospital-usage-for-western-australian-preterm-infants-under-12%C3%A2-months-of-age-a-population-based-data-linkage-study
#9
Natalie A Strobel, Sue Peter, Kimberley E McAuley, Daniel R McAullay, Rhonda Marriott, Karen M Edmond
OBJECTIVES: Our primary objective was to determine the incidence of hospital admission and emergency department presentation in Indigenous and non-Indigenous preterm infants aged postdischarge from birth admission to 11 months in Western Australia. Secondary objectives were to assess incidence in the poorest infants from remote areas and to determine the primary causes of hospital usage in preterm infants. DESIGN: Prospective population-based linked data set. SETTING AND PARTICIPANTS: All preterm babies born in Western Australia during 2010 and 2011...
January 18, 2017: BMJ Open
https://www.readbyqxmd.com/read/28100403/concordance-between-women-s-self-reported-reasons-for-cesarean-delivery-and-hospital-discharge-records
#10
Laura B Attanasio, Katy B Kozhimannil, Sindhu K Srinivas, Kristen H Kjerulff
BACKGROUND: Women's self-reports of whether they had a cesarean delivery are nearly 100% accurate, but there is little extant research on how accurately women self-report reasons for cesarean delivery when asked to recall this information in the postpartum period. OBJECTIVE: We compared women's self-reported reasons for cesarean with their hospital discharge records and examined correlates of variability in agreement between sources. METHODS: Data are from the First Baby Study, a cohort of 3,006 women who gave birth to their first baby between 2009 and 2011...
January 16, 2017: Women's Health Issues: Official Publication of the Jacobs Institute of Women's Health
https://www.readbyqxmd.com/read/28100222/gestational-age-and-1-year-hospital-admission-or-mortality-a-nation-wide-population-based-study
#11
Silvia Iacobelli, Evelyne Combier, Adrien Roussot, Jonathan Cottenet, Jean-Bernard Gouyon, Catherine Quantin
BACKGROUND: Describe the 1-year hospitalization and in-hospital mortality rates, in infants born after 31 weeks of gestational age (GA). METHODS: This nation-wide population-based study used the French medico-administrative database to assess the following outcomes in singleton live-born infants (32-43 weeks) without congenital anomalies (year 2011): neonatal hospitalization (day of life 1 - 28), post-neonatal hospitalization (day of life 29 - 365), and 1-year in-hospital mortality rates...
January 18, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28100207/rate-and-associated-factors-of-non-retention-of-mother-baby-pairs-in-hiv-care-in-the-elimination-of-mother-to-child-transmission-programme-gulu-uganda-a-cohort-study
#12
Gerald Obai, Ruth Mubeezi, Fredrick Makumbi
BACKGROUND: Poor retention in HIV care of mother-baby pairs remains a public health challenge in the elimination of mother-to-child transmission (eMTCT) of HIV. We determined the rate of non-retention and time to non-retention of mother-baby pairs and associated factors in Gulu district, Northern Uganda. METHODS: Mother-baby pairs enrolled into the eMTCT programme at Gulu Regional Referral Hospital (GRRH) and Lacor Hospital (LH) were retrospectively followed for 18 months...
January 18, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28099980/challenges-faced-in-translating-the-benefits-of-surfactant-replacement-therapy-to-a-resource-limited-setting
#13
N Hamilton, Helen Trotman
Aim To determine the challenges, if any, in translating the benefits of surfactant replacement therapy (SRT) to a resource-limited setting. Method This was a retrospective descriptive study comparing the outcome of 75 cases who received surfactant and 69 controls who did not at the University Hospital of the West Indies during the period 2001 to 2011. Descriptive analyses were performed. Statistical significance was taken at the level p < 0.05. Results Only 13% of neonates with respiratory distress syndrome received surfactant therapy...
January 18, 2017: American Journal of Perinatology
https://www.readbyqxmd.com/read/28099558/the-mortality-rate-after-hospital-discharge-in-patients-with-myelomeningocele-decreased-after-implementation-of-mandatory-flour-fortification-with-folic-acid
#14
Renato Manganelli Salomão, Tatiana Protzenko Cervante, José Francisco Manganelli Salomão, Soniza Vieira Alves Leon
Objective: To evaluate the mandatory folic acid fortification of flour on mortality rates after the hospital discharge of children born with myelomeningocele, the most affected age group and the most frequent cause of death. Methods: A retrospective study of 383 children born with myelomeningocele from January 1990 to December 2013 in a high-fetal-risk reference hospital. Results: A total of 39 patients died (10.1%),of which 23 (6%) died after discharge...
January 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/28099269/bilateral-leg-replantation-in-a-3-month-old-baby-after-a-knee-level-crush-amputation-a-2-year-follow-up
#15
Kresimir Bulic, Anko Antabak, Anto Dujmovic, Hrvoje Kisic, Mia Lorencin
We present a case of a successful bilateral leg replantation in a 3-month-old baby after a knee-level crush amputation with the loss of both knee joints. The legs were replanted after 4 hours of warm and an additional 2.5 and 3.5 hours of cold ischemia time. Both legs show motor and sensory reinnervation, without additional procedures performed on the right leg, and after a nerve reconstruction with cadaveric allografts on the left leg. Both replanted legs exhibit excellent bony and soft tissue growth. Two years after the injury, the patient is progressing well with rehabilitation, with favourable odds of having knee reconstructions performed at a later age...
January 18, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28098911/diagnosis-for-choroideremia-in-a-large-chinese-pedigree-by-next%C3%A2-generation-sequencing-ngs-and-non%C3%A2-invasive-prenatal-testing-nipt
#16
Li Zhu, Jingliang Cheng, Boxu Zhou, Chunli Wei, Weichan Yang, Dong Jiang, Iqra Ijaz, Xiaojun Tan, Rui Chen, Junjiang Fu
To develop an effective strategy to isolate and use cell‑free fetal DNA (cffDNA) for the combined use of next‑generation sequencing (NGS) for diagnosing choroideremia and non‑invasive prenatal testing (NIPT) for Y chromosome determination, a large Chinese family with an X‑linked recessive disease, choroideremia, was recruited. Cell‑free DNA was extracted from maternal plasma, and SRY polymerase chain reaction amplification was performed using NIPT. Sanger sequencing was subsequently used for fetal amniotic fluid DNA verification...
January 13, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28095810/neonatal-screening-for-congenital-adrenal-hyperplasia-in-southern-brazil-a-population-based-study-with-108-409-infants
#17
Cristiane Kopacek, Simone Martins de Castro, Mayara Jorgens Prado, Claudia Maria Dornelles da Silva, Luciana Amorim Beltrão, Poli Mara Spritzer
BACKGROUND: Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder associated with inborn errors of steroid metabolism. 21-hydroxylase enzyme deficiency occurs in 90 to 95% of all cases of CAH, with accumulation of 17 hydroxyprogesterone (17-OHP). Early diagnosis of CAH based on newborn screening is possible before the development of symptoms and allows proper treatment, correct sex assignment, and reduced mortality rates. This study describes the results obtained in the first year of a public CAH screening program in the state of Rio Grande do Sul, Brazil...
January 17, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28095617/probing-forebrain-to-hindbrain-circuit-functions-in-xenopus
#18
REVIEW
Darcy B Kelley, Taffeta M Elliott, Ben J Evans, Ian C Hall, Elizabeth C Leininger, Heather J Rhodes, Ayako Yamaguchi, Erik Zornik
The vertebrate hindbrain includes neural circuits that govern essential functions including breathing, blood pressure and heart rate. Hindbrain circuits also participate in generating rhythmic motor patterns for vocalization. In most tetrapods, sound production is powered by expiration and the circuitry underlying vocalization and respiration must be linked. Perception and arousal are also linked; acoustic features of social communication sounds - e.g. a baby's cry - can drive autonomic responses. The close links between autonomic functions that are essential for life and vocal expression have been a major in vivo experimental challenge...
January 17, 2017: Genesis: the Journal of Genetics and Development
https://www.readbyqxmd.com/read/28095312/neural-correlates-of-babyish-adult-face-processing-in-men
#19
Hirokazu Doi, Minoru Morikawa, Nobuyuki Inadomi, Katsuhiko Aikawa, Masataka Uetani, Kazuyuki Shinohara
The morphological characteristics of an infant's face are collectively referred to as baby schema or babyishness. It has been well established that infant traits are implicitly projected, or overgeneralized, to adults with babyish facial features. However, few studies to date have investigated the neural underpinnings of such overgeneralization. In the present study, we addressed this issue by comparing neural activations elicited by baby-faced and mature-faced adult faces in men using fMRI. We found increased activations in clusters surrounding the bilateral insula, bilateral anterior cingulate cortex, and right inferior frontal gyrus, which have been previously linked to the processing of facial attractiveness and infant-related information...
January 14, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28094678/orthotic-treatment-of-positional-brachycephaly-associated-with-osteogenesis-imperfecta
#20
Carolina G Matarazzo, Gerd Schreen, Camilla D do Lago-Rizzardi, Maria Stella Peccin, Fernando Cg Pinto
Osteogenesis imperfecta is an inherited disorder of the connective tissue characterized primarily by fractures with no or small causal antecedents and extremely variable clinical presentation. The disorder requires a global and, therefore, multidisciplinary therapeutic approach that should aim, among other aspects, at the prevention and treatment of deformities resulting from osteogenesis imperfecta. Due to limitations related to bony deformities, it can be difficult to place these infants in a variety of positions that would help remediate skull deformities, so a cranial orthosis becomes the therapy of choice...
January 1, 2017: Prosthetics and Orthotics International
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