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Wei Zhang, Hong-ru Wu, Qiang-kun Liang, Yun-xia Li, Yan-yu Lu, Yao Long, Yao Zhu, Hong-fang Li
OBJECTIVE: To extract two kinds of phenols 4-hydroxy-3, 5-dimethoxy-4-(2-oxopropyl) cyclohexa-2, 5-dien-l-one and 6-methoxy-5,7-dihydroxy coumarin (named as I and H compounds respectively) from Ajania salicifolia and to investigate their antioxidation and cytotoxicity to tumors and explore their pro-apoptosis mechanism. METHODS: The antioxidant activities of two compounds were assessed by ABTS and DPPH radical-scavenging assays. Two compounds were evaluated for their cytotoxicity against human chronic myelogenous leukemia (K562) cells using the MIT assay...
September 2015: Chinese Journal of Applied Physiology
J L Moyano Calvo, E Blanco Palenciano, A Beato Moreno, M Gutiérrez González, A Pérez-Lanzac Lorca, A Samaniego Torres, J A Montaño, J Fernández Castiñeiras
INTRODUCTION: The natural history of the superficial carcinoma of bladder is characterized by his high rate of recurrence and by the aptitude to progress to higher stages. We are going to investigate the capacity of prediction for tumor recurrence of protein p53, antigen Ki-67, E Cadherin and Beta Catenin MATERIAL AND METHOD: 88 T1 tumors with a median of free time of disease of 36 months. 58% of the serie has received prophylactic treatment with BCG 81 mg. weekly for six weeks...
October 2006: Actas Urologicas Españolas
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