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Idiopathic sudden sensorineural hearing loss

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https://www.readbyqxmd.com/read/28423374/hyperbaric-oxygen-therapy-as-adjuvant-treatment-for-idiopathic-sudden-sensorineural-hearing-loss-after-failure-of-systemic-steroids
#1
Seiji Hosokawa, Ken-Ichi Sugiyama, Goro Takahashi, Yu-Ichi Hashimoto, Kumiko Hosokawa, Satoru Takebayashi, Hiroyuki Mineta
We evaluated the outcomes of and prognostic factors for idiopathic sudden sensorineural hearing loss (ISSNHL) treated with adjuvant hyperbaric oxygen therapy (HBOT). A retrospective review of clinical data was performed for 167 patients with ISSNHL who failed to respond to systemic steroids and were treated by adjuvant HBOT at Shizuoka Saiseikai General Hospital. We analysed the clinical outcomes, the averaged 5-frequency hearing level after systemic steroids, patient age, the interval between post-steroids and pre-HBOT, vertigo as a complication, the presence of diabetes mellitus, smoking history, and hypertension...
April 20, 2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/28417106/comparative-analysis-of-the-combined-therapeutic-effects-of-lipoprostaglandin-e1-on-sudden-idiopathic-sensorineural-hearing-loss
#2
Haeng Seon Shim, Joon Soo Kim, Myung Gu Kim
BACKGROUND AND OBJECTIVES: Viral and vascular disorders are considered to be a major cause of idiopathic sudden sensorineural hearing loss (ISSNHL). Lipoprostaglandin E1 (lipo-PGE1) has vasodilating activity and has been used to treat ISSNHL. The purpose of this study was to determine the specific therapeutic effects of lipo-PGE1 and compare them to other treatment modalities for ISSNHL. SUBJECTS AND METHODS: The study group had 1,052 patients diagnosed with ISSNHL...
April 2017: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/28417102/prognostic-factors-for-recovery-from-sudden-sensorineural-hearing-loss-a-retrospective-study
#3
Woo Seok Kang, Chan Joo Yang, Myungjoo Shim, Chan Il Song, Tae Su Kim, Hyun Woo Lim, Joong Ho Ahn, Hong Ju Park, Jong Woo Chung
BACKGROUND AND OBJECTIVES: This study aimed to investigate prognostic factors in patients with idiopathic sudden sensorineural hearing loss (ISSNHL). SUBJECTS AND METHODS: From January 2007 to December 2011, a retrospective chart review identified 494 consecutive patients with ISSNHL. Demographic, audiometric, and clinical data were analyzed using a logistic regression test. RESULTS: Hearing recovery from ISSNHL was significantly associated with factors such as age, duration from onset of symptoms to commencement of treatment, severity of the initial pure tone threshold, and the treatment method...
April 2017: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/28415914/sealing-of-the-round-and-oval-window-niches-with-triamcinolone-soaked-fascia-as-salvage-surgical-therapy-in-sudden-sensorineural-hearing-loss
#4
Benjamin Loader, Rudolf Seemann, Claudia Atteneder, Elisabeth Sterrer, Peter Franz, Claudia Lill
CONCLUSIONS: Triamcinolone-soaked fascia seems to show better hearing improvement when added to tympanotomy for sudden idiopathic sensorineural hearing loss (SSHL), compared to fascia round window occlusion without triamcinolone. OBJECTIVES: To analyse if adding triamcinolone to sealing the round and oval window niches with fascia results in improved audiological outcome for acute SNHL. METHODS: Fifty-three patients (27m:43 ± 12 years, 26f:45 ± 14 years) with acute SSHL ≥50dB over 3 frequencies, who failed primary therapy, underwent transcanal tympanotomy...
April 18, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28414276/studying-the-association-between-sudden-hearing-loss-and-dna-n-methyltransferase-1-dnmt1-genetic-polymorphism
#5
Kübra Şeker Yıldız, Kasım Durmuş, Gonca Dönmez, Serdal Arslan, Emine Elif Altuntaş
OBJECTIVE: The aim of the present study was to investigate whether there was any relationship between some DNA N-methyltransferase 1 (DNMT1) polymorphisms and susceptibility to idiopathic sudden sensorineural hearing loss (ISSHL) in ISSHL patients. MATERIAL AND METHODS: We investigated 90 patients diagnosed with ISSHL and a control group composed of 75 age- and gender-matched healthy individuals. DNA was extracted from the blood samples by phenol-chloroform method...
April 17, 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/28412992/acute-otitis-media-associated-bilateral-sudden-hearing-loss-case-report-and-literature-review
#6
A Smith, I Gutteridge, D Elliott, M Cronin
BACKGROUND: Sudden sensorineural hearing loss is a rare otological condition with potential for dire outcomes including permanent hearing loss. Although the majority of cases are deemed idiopathic, bilateral sudden sensorineural hearing loss represents a rare subset typically related to systemic conditions, with higher morbidity and mortality. A controversial association with acute otitis media has been reported, with few bilateral cases published in the literature. CASE REPORT: A very rare case of bilateral sudden sensorineural hearing loss associated with acute otitis media is described, with a review of the literature...
April 17, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28397567/framingham-risk-score-as-a-prognostic-predictor-of-sudden-sensorineural-hearing-loss-a-preliminary-study
#7
Young-Soo Chang, Ji Eun Choi, Jungmin Ahn, Nam-Gyu Ryu, Il Joon Moon, Sung Hwa Hong, Yang-Sun Cho, Won-Ho Chung
OBJECTIVES/HYPOTHESIS: Predicting the prognosis of idiopathic sudden sensorineural hearing loss (ISSHL) remains challenging. This investigation aimed to apply Framingham Risk Scores (FRS) to assess the combination of prognostic factors following ISSHL and investigate the predictive role of FRS in patients with multiple comorbidities including hypertension, diabetes, and hyperlipidemia. STUDY DESIGN: Retrospective study. METHODS: Twenty-one patients presenting with unilateral idiopathic sudden sensorineural hearing loss and multiple comorbidities were surveyed...
May 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28397037/assessment-of-balance-and-vestibular-functions-in-patients-with-idiopathic-sudden-sensorineural-hearing-loss
#8
Jia Liu, Ren-Hong Zhou, Bo Liu, Yang-Ming Leng, Jing-Jing Liu, Dong-Dong Liu, Su-Lin Zhang, Wei-Jia Kong
This study investigated the relationship among the severity of hearing impairment, vestibular function and balance function in patients with idiopathic sudden sensorineural hearing loss (ISSNHL). A total of 35 ISSNHL patients (including 21 patients with vertigo) were enrolled. All of the patients underwent audiometry, sensory organization test (SOT), caloric test, cervical vestibular-evoked myogenic potential (cVEMP) test and ocular vestibular-evoked myogenic potential (oVEMP) test. Significant relationship was found between vertigo and hearing loss grade (P=0...
April 2017: Journal of Huazhong University of Science and Technology. Medical Sciences
https://www.readbyqxmd.com/read/28394652/nationwide-epidemiological-survey-of-idiopathic-sudden-sensorineural-hearing-loss-in-japan
#9
Ryosuke Kitoh, Shin-Ya Nishio, Kaoru Ogawa, Sho Kanzaki, Naohito Hato, Michihiko Sone, Satoshi Fukuda, Akira Hara, Tetsuo Ikezono, Kotaro Ishikawa, Satoshi Iwasaki, Kimitaka Kaga, Seiji Kakehata, Atsushi Matsubara, Tatsuo Matsunaga, Takaaki Murata, Yasushi Naito, Takashi Nakagawa, Kazunori Nishizaki, Yoshihiro Noguchi, Hajime Sano, Hiroaki Sato, Mikio Suzuki, Hideo Shojaku, Haruo Takahashi, Hidehiko Takeda, Testuya Tono, Hiroshi Yamashita, Tatsuya Yamasoba, Shin-Ichi Usami
OBJECTIVES: Using a large-scale nationwide survey database, we investigated the epidemiological characteristics for idiopathic SSNHL in Japan. METHODS: The subjects for this analysis were patients registered in a Japanese multicentre database between April 2014 and March 2016. A total of 3419 idiopathic SSNHL patients were registered in the database, and the clinical characteristics of the idiopathic SSNHL patients were obtained. Several factors associated with the severity of hearing impairment and prognosis were then investigated...
April 10, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28376930/predictors-of-hearing-recovery-in-patients-with-severe-sudden-sensorineural-hearing-loss
#10
Daniel Weiss, Armin Julius Böcker, Mario Koopmann, Eleftherios Savvas, Matthias Borowski, Claudia Rudack
BACKGROUND: Sudden sensorineural hearing loss (SSHL) is a disease, which severely affects the patient's social and relational life. The underlying pathomechanisms have not been finally clarified yet and outcome is not predictable. METHODS: We conducted a retrospective study in order to identify parameters that influence hearing recovery. The data base contains results of basic otoneurological tests and clinical parameters of 198 patients with idiopathic SSHL of at least 60 dB in at least four frequencies, diagnosed and treated at the University Hospital of Münster, Germany, between 1999 and 2015...
April 4, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28366083/idiopathic-sudden-sensorineural-hearing-loss-and-acute-low-tone-sensorineural-hearing-loss-a-comparison-of-the-results-of-a-nationwide-epidemiological-survey-in-japan
#11
Tadao Yoshida, Michihiko Sone, Ryosuke Kitoh, Shin-Ya Nishio, Kaoru Ogawa, Sho Kanzaki, Naohito Hato, Satoshi Fukuda, Akira Hara, Tetsuo Ikezono, Kotaro Ishikawa, Satoshi Iwasaki, Kimitaka Kaga, Seiji Kakehata, Atsushi Matsubara, Tatsuo Matsunaga, Takaaki Murata, Yasushi Naito, Takashi Nakagawa, Kazunori Nishizaki, Yoshihiro Noguchi, Hajime Sano, Hiroaki Sato, Mikio Suzuki, Hideo Shojaku, Haruo Takahashi, Hidehiko Takeda, Testuya Tono, Hiroshi Yamashita, Tatsuya Yamasoba, Shin-Ichi Usami
OBJECTIVES: The aim of this study was to investigate the differences between idiopathic sudden sensorineural hearing loss (SSNHL), and acute low-tone sensorineural hearing loss (ALHL) using the results of a nationwide survey database in Japan and to analyze the variables associated with their clinical features and the severity of hearing impairment, treatment, and prognosis. METHODS: Participants were patients registered between April 2014 and March 2016 in a multicenter epidemiological survey database involving 30 university hospitals and medical centers across Japan...
April 1, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28366076/relationships-among-drinking-and-smoking-habits-history-of-diseases-body-mass-index-and-idiopathic-sudden-sensorineural-hearing-loss-in-japanese-patients
#12
Mitsumasa Umesawa, Gen Kobashi, Ryoshuke Kitoh, Shin-Ya Nishio, Kaoru Ogawa, Naohito Hato, Michihiko Sone, Satoshi Fukuda, Akira Hara, Tetsuo Ikezono, Kotaro Ishikawa, Satoshi Iwasaki, Kimitaka Kaga, Seiji Kakehata, Atsushi Matsubara, Tatsuo Matsunaga, Takaaki Murata, Yasushi Naito, Takashi Nakagawa, Kazunori Nishizaki, Yoshihiro Noguchi, Hajime Sano, Hiroaki Sato, Mikio Suzuki, Hideo Shojaku, Haruo Takahashi, Hidehiko Takeda, Tetsuya Tono, Hiroshi Yamashita, Tatsuya Yamasoba, Shin-Ichi Usami
OBJECTIVES: To present the cardiovascular risk factors in idiopathic sudden sensorineural hearing loss (SSNHL) patients enrolled in a nationwide epidemiological survey of hearing disorders in Japan. MATERIALS AND METHODS: We compiled the cardiovascular risk factors in 3073 idiopathic SSNHL subjects (1621 men and 1452 women) and compared their proportions with controls as part of the National Health and Nutrition Survey in Japan, 2014. The cardiovascular risk factors consisted of drinking and smoking habits, a history of five conditions related to cardiovascular disease and body mass index...
April 1, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28366034/prognostic-impact-of-gene-polymorphisms-in-patients-with-idiopathic-sudden-sensorineural-hearing-loss
#13
Ryosuke Kitoh, Shin-Ya Nishio, Shin-Ichi Usami
OBJECTIVE: To investigate whether genetic polymorphisms (single-nucleotide polymorphism [SNPs]) have a prognostic influence on hearing recovery after standardized corticosteroid therapy. METHODS: A total of 192 gene samples from idiopathic sudden sensorineural hearing loss (SSNHL) patients registered in the Intractable Inner Ear Disease Gene Bank were enrolled and, as the candidate genes, 16 SNPs from 13 genes were selected for this study. Fischer's exact test was used to compare allele frequencies in each SNP between the patients with good hearing recovery and patients with poor hearing recovery...
April 1, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28359220/the-effect-of-initial-treatment-on-hearing-prognosis-in-idiopathic-sudden-sensorineural-hearing-loss-a-nationwide-survey-in-japan
#14
Masahiro Okada, Naohito Hato, Shin-Ya Nishio, Ryosuke Kitoh, Kaoru Ogawa, Sho Kanzaki, Michihiko Sone, Satoshi Fukuda, Akira Hara, Tetsuo Ikezono, Kotaro Ishikawa, Satoshi Iwasaki, Kimitaka Kaga, Seiji Kakehata, Atsushi Matsubara, Tatsuo Matsunaga, Takaaki Murata, Yasushi Naito, Takashi Nakagawa, Kazunori Nishizaki, Yoshihiro Noguchi, Hajime Sano, Hiroaki Sato, Mikio Suzuki, Hideo Shojaku, Haruo Takahashi, Hidehiko Takeda, Tetsuya Tono, Hiroshi Yamashita, Tatsuya Yamasoba, Shin-Ichi Usami
OBJECTIVE: To investigate the hearing prognosis of idiopathic sudden sensorineural hearing loss (SSNHL) treated with different initial therapies. METHODS: Subjects consisted of patients diagnosed with idiopathic SSNHL within 7 days from onset and showing severe hearing loss (≥60 dB), who were registered in a Japanese multicenter database between April 2014 and March 2016. Subjects were divided into four groups according to initial therapy: (1) steroids, (2) steroids + Prostaglandins (PGs), (3) intratympanic steroids (ITS), and (4) no steroids...
March 31, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28290919/intratympanic-methylprednisolone-perfusion-as-a-salvage-treatment-for-profound-idiopathic-sudden-sensorineural-hearing-loss
#15
Y Dai, L Lu, J Hou, X Yang, H Li, Y Yang, W She
OBJECTIVE: This study aimed to examine the effectiveness of intratympanic methylprednisolone perfusion as salvage treatment for profound idiopathic sudden sensorineural hearing loss. METHODS: A retrospective clinical study of 97 patients with unilateral profound idiopathic sudden sensorineural hearing loss was performed. In all, 83 patients who received salvage intratympanic methylprednisolone perfusion plus conventional treatment (except for steroids) as the second-line therapy were assigned to the study group, while 14 patients who received conventional treatment alone were assigned to the comparison group...
May 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28286637/a-retrospective-study-of-the-clinical-characteristics-and-post-treatment-hearing-outcome-in-idiopathic-sudden-sensorineural-hearing-loss
#16
Purushothaman Ganesan, Purushothaman Pavanjur Kothandaraman, Simham Swapna, Vinaya Manchaiah
The purpose of this retrospective study was to analyze the clinical characteristics and document hearing recovery in patients with idiopathic sudden sensorineural hearing loss (ISSNHL). 122 patients diagnosed with unilateral ISSNHL, from March 2009 to December 2014, were treated with oral steroids and pentoxifylline. Hearing change was evaluated by comparing pre-treatment and post-treatment pure-tone average (PTA) (500, 1K, and 2K Hz), and categorized into complete, partial, and no recovery of hearing. T-test, Wilcoxon Signed Rank test and Regression analysis were employed to analyze the statistical significance...
February 1, 2017: Audiology Research
https://www.readbyqxmd.com/read/28261890/ozone-prevents-cochlear-damage-from-ischemia-reperfusion-injury-in-guinea-pigs
#17
Merih Onal, Cagdas Elsurer, Nebil Selimoglu, Mustafa Yilmaz, Ender Erdogan, Jale Bengi Celik, Oznur Kal, Ozkan Onal
The cochlea is an end organ, which is metabolically dependent on a nutrient and oxygen supply to maintain its normal physiological function. Cochlear ischemia and reperfusion (IR) injury is considered one of the most important causes of human idiopathic sudden sensorineural hearing loss. The aim of the present study was to study the efficacy of ozone therapy against cochlear damage caused by IR injury and to investigate the potential clinical use of this treatment for sudden deafness. Twenty-eight guinea pigs were randomized into four groups...
March 5, 2017: Artificial Organs
https://www.readbyqxmd.com/read/28224621/laboratory-assessment-of-sudden-sensorineural-hearing-loss-a-case-control-study
#18
Tommaso Fasano, Thelma A Pertinhez, Lorenzo Tribi, Daniela Lasagni, Annalisa Pilia, Luigi Vecchia, Roberto Baricchi, Giovanni Bianchin
OBJECTIVES/HYPOTHESIS: Sudden sensorineural hearing loss (SSHL) is an otologic emergency that affects five to 30 subjects per 100,000/year. The cause of SSHL remains unknown or uncertain in 70% to 90% of cases, and treatment decisions are usually made without knowing the etiology. STUDY DESIGN: Prospective case-control study. METHODS: One hundred thirty-one idiopathic SSHL patients were recruited from January 2014 to June 2015 in concordance with the Statements of Clinical Practice Guideline and divided into groups according to the disease severity...
February 22, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28177591/insulin-effect-on-hearing-recovery-in-idiopathic-sudden-sensorineural-hearing-loss-retrospective-study-of-145-patients
#19
O H Ryu, J R Chao, M G Choi, C Kim, J-G Suh, Y Y Kim, C H Park, H-J Kim, J H Lee
No abstract text is available yet for this article.
February 8, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28159388/correlation-between-auditory-brainstem-response-and-hearing-prognosis-in-idiopathic-sudden-sensorineural-hearing-loss-patients
#20
Hung-Che Lin, Yu-Ching Chou, Chih-Hung Wang, Li-Wen Hung, Cheng-Ping Shih, Bor-Hwang Kang, Wen-Ying Yeh, Hsin-Chien Chen
OBJECTIVE: To investigate the latency and amplitude of auditory brainstem response (ABR) and hearing prognosis in patients with idiopathic sudden sensorineural hearing loss (ISSNHL). METHODS: Patients with ISSNHL were classified into four different recovery groups. All patients' clinical and demographic features were analyzed. Two-channel ABRs were collected in response to click stimuli at 90dB nHL. ABR amplitudes for wave I and ABR latency for waves I, III, and V were analyzed...
January 31, 2017: Auris, Nasus, Larynx
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