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https://www.readbyqxmd.com/read/29680695/microbiological-quality-and-antimicrobial-resistance-characterization-of-salmonella-spp-in-fresh-milk-value-chains-in-ghana
#1
Angela Parry-Hanson Kunadu, Mark Holmes, Eric L Miller, Andrew J Grant
Consumer perception of poor hygiene of fresh milk products is a major barrier to promotion of milk consumption as an intervention to alleviate the burden of malnutrition in Ghana. Fresh milk is retailed raw, boiled, or processed into unfermented cheese and spontaneously fermented products in unlicensed outlets. In this study, we have determined microbiological quality of informally retailed fresh milk products and characterized the genomic diversity and antimicrobial resistance (AMR) patterns of non-typhoidal Salmonella (NTS) in implicated products...
April 14, 2018: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/29670876/design-synthesis-and-evaluation-of-dihydrobenzo-cd-indole-6-sulfonamide-as-tnf-%C3%AE-inhibitors
#2
Xiaobing Deng, Xiaoling Zhang, Bo Tang, Hongbo Liu, Qi Shen, Ying Liu, Luhua Lai
Tumor necrosis factor-α (TNF-α) plays a pivotal role in inflammatory response. Dysregulation of TNF can lead to a variety of disastrous pathological effects, including auto-inflammatory diseases. Antibodies that directly targeting TNF-α have been proven effective in suppressing symptoms of these disorders. Compared to protein drugs, small molecule drugs are normally orally available and less expensive. Till now, peptide and small molecule TNF-α inhibitors are still in the early stage of development, and much more efforts should be made...
2018: Frontiers in Chemistry
https://www.readbyqxmd.com/read/29604320/examining-consumer-luxury-brand-related-behavior-intentions-in-a-social-media-context-the-moderating-role-of-hedonic-and-utilitarian-motivations
#3
David Martín-Consuegra, Estrella Díaz, Mar Gómez, Arturo Molina
Luxury brand marketers have recently turned their attention to customer-driven social media devoted to their brands. The key concepts of involvement, interaction and behavioral intention provide the theoretical foundation to investigate luxury brands. The purpose of this study is to test a model that analyzes the relationship among brand involvement, consumer-brand interaction and behavioral intention in the context of luxury brand-related activities on social media. Based on content value theory, the present research identifies the moderating role of utilitarian/hedonic motivations on the relationships proposed...
March 28, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29590349/uk-consumer-perceptions-of-a-novel-till-receipt-traffic-light-nutrition-system
#4
Matthew Cole, Hayden Peek, Daniel Cowen
Front-of-pack (FoP) traffic light nutrition labelling has been widely proposed as a tool to improve public health nutrition. Current evidence suggests that whilst consumers generally find them to be useful and an important source of information about a particular food or ingredient, this may have limited value in isolation when considering a person's overall nutritional intake. This study sought to examine UK consumers' use of existing FoP traffic light food labelling and ascertain public perception of a novel 'till-receipt' summary providing nutritional information about consumers entire shopping purchases...
March 26, 2018: Health Promotion International
https://www.readbyqxmd.com/read/29570893/comparison-of-dispensed-medications-and-forensic-toxicological-findings-to-assess-pharmacotherapy-in-the-swedish-population-2006-to-2013
#5
Jonas Forsman, Heidi Taipale, Thomas Masterman, Jari Tiihonen, Antti Tanskanen
PURPOSE: To investigate person-level agreement between medication exposure as predicted using the PRE2DUP (a prescription-based design to estimate continuous drug use) method and postmortem toxicological findings, in the Swedish population during the years 2006 to 2013. METHODS: Using the Swedish National Board of Forensic Medicine's toxicology database and the Swedish National Board of Health and Welfare's registries on causes of death, dispensed medications, and in-patient care, forensic-toxicological findings were compared with prescription-based estimates of drug use for 27 medications...
March 23, 2018: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/29564376/the-ratio-of-patient-body-mass-index-to-age-a-cost-effective-implant-selection-guideline-for-total-knee-arthroplasty
#6
Feroz A Osmani, Nicholas Bolz, Khalid Odeh, Craig Bearison, Ran Schwarzkopf, Richard Iorio
Background: We sought to develop an objective implant selection guideline based on the ratio of patient body mass index (BMI) to age in order to select implants preoperatively and reduce cost while maintaining quality. The BMI-to-age ratio can be used to distinguish patient demand and select those patients who may benefit from newer technology and higher cost implants and those who would do well with standard-demand implants. Methods: A retrospective analysis investigated the types of implants received by patients undergoing total knee arthroplasty from January 2012 to August 2014...
March 2018: Arthroplasty Today
https://www.readbyqxmd.com/read/29558696/exploring-the-influence-of-consumer-characteristics-on-veal-credence-and-experience-guarantee-purchasing-motivators
#7
H Resano, A M Olaizola, M Dominguez-Torreiro
In Europe, in the last decades, public administration has encouraged extensive livestock farming systems, usually related to high quality meat and the preservation of endangered local breeds. Nevertheless, its continuity in the near future should be based on adapting it to the market requirements. This paper investigates consumers' preferences heterogeneity towards veal attributes, as well as the linkage between a wide range of consumer traits and attributes that motivate purchasing of veal with unique characteristics...
March 5, 2018: Meat Science
https://www.readbyqxmd.com/read/29541764/us-national-trends-in-mortality-from-acute-myocardial-infarction-and-heart-failure-policy-success-or-failure
#8
Paula Chatterjee, Karen E Joynt Maddox
Importance: Hospitals in the United States have been subject to mandatory public reporting of mortality rates for acute myocardial infarction (AMI) and heart failure (HF) since 2007 and to value-based payment programs for these conditions since 2011. However, whether hospitals with initially poor baseline performance have improved relative to other hospitals under these programs, and whether patterns of improvement differ by condition, is unknown. Understanding trends within public reporting and value-based payment can inform future efforts in these areas...
March 14, 2018: JAMA Cardiology
https://www.readbyqxmd.com/read/29534061/socioeconomic-benefit-to-individuals-of-achieving-2020-targets-for-four-neglected-tropical-diseases-controlled-eliminated-by-innovative-and-intensified-disease-management-human-african-trypanosomiasis-leprosy-visceral-leishmaniasis-chagas-disease
#9
Edeltraud J Lenk, William K Redekop, Marianne Luyendijk, Christopher Fitzpatrick, Louis Niessen, Wilma A Stolk, Fabrizio Tediosi, Adriana J Rijnsburger, Roel Bakker, Jan A C Hontelez, Jan H Richardus, Julie Jacobson, Epke A Le Rutte, Sake J de Vlas, Johan L Severens
BACKGROUND: The control or elimination of neglected tropical diseases (NTDs) has targets defined by the WHO for 2020, reinforced by the 2012 London Declaration. We estimated the economic impact to individuals of meeting these targets for human African trypanosomiasis, leprosy, visceral leishmaniasis and Chagas disease, NTDs controlled or eliminated by innovative and intensified disease management (IDM). METHODS: A systematic literature review identified information on productivity loss and out-of-pocket payments (OPPs) related to these NTDs, which were combined with projections of the number of people suffering from each NTD, country and year for 2011-2020 and 2021-2030...
March 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29533318/patient-perceptions-of-servicescape-in-healthcare-a-systematic-review-of-the-literature
#10
Ilhan Sag, Ferhat Devrim Zengul, Amy Yarbrough Landry
Many hospitals are competing for survival in their service areas. Because of intense competition within markets, hospitals are developing strategies to differentiate themselves. One way to do so is to create a physical infrastructure and service environment that generate a positive impact on patient perceptions. The purpose of this study is to review the literature on servicescape (i.e., a total impression of a service encounter developed through the use of human senses) and its effects on service quality and patient outcomes in healthcare settings...
March 2018: Journal of Healthcare Management / American College of Healthcare Executives
https://www.readbyqxmd.com/read/29521892/provider-reimbursement-following-the-affordable-care-act
#11
Brandon Bowling, David Newman, Craig White, Ashley Wood, Alberto Coustasse
Decreasing health care expenditures has been one of the main objectives of the Affordable Care Act. To achieve this goal, the Centers for Medicare and Medicaid Services (CMS) has been tasked with experimenting with provider reimbursement methods in an attempt to increase quality, while decreasing costs. The purpose of this research was to study the effects of the Affordable Care Act on physician reimbursement rates from CMS to determine the most cost-effective method of delivering health care services. The CMS has experimented with payment methods in an attempt to increase cost-effectiveness...
March 9, 2018: Health Care Manager
https://www.readbyqxmd.com/read/29519605/time-driven-activity-based-cost-comparison-of-prostate-cancer-brachytherapy-and-intensity-modulated-radiation-therapy
#12
Sunil W Dutta, Kristine Bauer-Nilsen, Jason C Sanders, Daniel M Trifiletti, Bruce Libby, Donna H Lash, Melody Lain, Deborah Christodoulou, Constance Hodge, Timothy N Showalter
PURPOSE: To evaluate the delivery cost of frequently used radiotherapy options offered to patients with intermediate- to high-risk prostate cancer using time-driven activity-based costing and compare the results with Medicare reimbursement and relative value units (RVUs). METHODS AND MATERIALS: Process maps were created to represent each step of prostate radiotherapy treatment at our institution. Salary data, equipment purchase costs, and consumable costs were factored into the cost analysis...
March 5, 2018: Brachytherapy
https://www.readbyqxmd.com/read/29503290/measuring-the-effect-of-social-determinants-on-patient-outcomes-a-systematic-literature-review
#13
Andrew J Knighton, Brad Stephenson, Lucy A Savitz
Given the movement towards value-based purchasing in the United States, health care leaders need methods to characterize and address the complex effect that social determinants have on health care outcomes. This systematic literature review was specifically designed to understand current research on the effect that patient material and social deprivation has on health care delivery outcomes and the potential benefit of clinical interventions designed to mediate this effect. A total of 310 studies were identified for review with 80 studies included in the final synthesis...
2018: Journal of Health Care for the Poor and Underserved
https://www.readbyqxmd.com/read/29501946/identification-of-pyrazolo-3-4-e-1-4-thiazepin-based-cyp51-inhibitors-as-potential-chagas-disease-therapeutic-alternative-in-vitro-and-in-vivo-evaluation-binding-mode-prediction-and-sar-exploration
#14
Ludmila Ferreira de Almeida Fiuza, Raiza Brandão Peres, Marianne Rocha Simões-Silva, Patricia Bernardino da Silva, Denise da Gama Jaen Batista, Cristiane França da Silva, Aline Nefertiti Silva da Gama, Tummala Rama Krishna Reddy, Maria de Nazaré Correia Soeiro
American trypanosomiasis or Chagas disease (CD) is a vector borne pathology caused by the parasite Trypanosoma cruzi (T. cruzi), which remains a serious global health problem. The current available treatment for CD is limited to two nitroderivatives with limited efficacy and several side effects. The rational design of ergosterol synthetic route inhibitors (e.g. CYP51 inhibitors) represents a promising strategy for fungi and trypanosomatids, exhibiting excellent anti-T.cruzi activity in pre-clinical assays...
February 23, 2018: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/29496604/comparison-of-two-front-of-package-nutrition-labeling-schemes-and-their-explanation-on-consumers-perception-of-product-healthfulness-and-food-choice
#15
Pamela J Lundeberg, Dan J Graham, Gina S Mohr
OBJECTIVE: Front-of-package (FOP) nutrition labels are increasingly used to present nutritional information to consumers. A variety of FOP nutrition schemes exist for presenting condensed nutrition information. The present study directly compared two symbolic FOP labeling systems -traffic light and star-based schemes - with specific regard to healthfulness perception and purchase intention for a variety of products. Additionally, this study investigated which method of message framing (gain, loss, gain + loss) would best enable individuals to effectively utilize the FOP labels...
February 26, 2018: Appetite
https://www.readbyqxmd.com/read/29477389/an-overview-of-value-perspective-and-decision-context-a-health-economics-approach-an-ispor-special-task-force-report-2
#16
Louis P Garrison, Mark V Pauly, Richard J Willke, Peter J Neumann
The second section of our Special Task Force builds on the discussion of value and perspective in the previous article of the report by 1) defining a health economics approach to the concept of value in health care systems; 2) discussing the relationship of value to perspective and decision context, that is, how recently proposed value frameworks vary by the types of decisions being made and by the stakeholders involved; 3) describing the patient perspective on value because the patient is a key stakeholder, but one also wearing the hat of a health insurance purchaser; and 4) discussing how value is relevant in the market-based US system of mixed private and public insurance, and differs from its use in single-payer systems...
February 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/29473803/messy-but-fair-the-aca-s-hospital-value-based-purchasing-program-and-the-notice-and-comment-process
#17
Janus Pan
The Centers for Medicare and Medicaid Services (CMS) promulgated a new Medicare program called the Value-Based Purchasing Program (VBPP) as part of the 2010 Affordable Care Act (ACA). Like many other regulatory agencies, CMS used the Notice-and-Comment process to issue proposed rules, solicit public comments, and then publish final rules. Conventional literature suggests that CMS should disproportionately favor business interests during the Notice-and-Comment process, mainly due to the business interests' greater resources and capacity to draft well-reasoned comments...
July 2017: Journal of Legal Medicine
https://www.readbyqxmd.com/read/29471742/does-missed-care-in-isolated-rural-hospitals-matter
#18
Jessica G Smith
Missed care is associated with adverse outcomes such as patient falls and decreased nurse job satisfaction. Although studied in populations of interest such as neonates, children, and heart failure patients, there are no studies about missed care in rural hospitals. Reducing care omissions in rural hospitals might help improve rural patient outcomes and ensure that rural hospitals can remain open in an era of hospital reimbursement dependent on care outcomes, such as through value-based purchasing. Understanding the extent of missed nursing care and its implications for rural populations might provide crucial information to alert rural hospital administrators and nurses about the incidence and influence of missed care on health outcomes...
February 1, 2018: Western Journal of Nursing Research
https://www.readbyqxmd.com/read/29450402/modeling-the-consumer-s-perception-of-experiential-marketing-in-the-romanian-private-ophthalmologic-services
#19
Consuela-Mădălina Gheorghe, Iuliana-Raluca Gheorghe, Victor Lorin Purcărea
Introduction. The importance of experience in marketing grew, as the concept itself is very personal and difficult to measure. Experience turns out to be complicated but once placed in a context it gets significant features. As the health care competitive environment increases, marketers are looking for new and effective methods of engaging consumers by using experiential marketing strategies. Moreover, little is known about the consumers' perceptions related to ophthalmologic services. Aim. The objective of this paper was to measure the consumer's perception of experiential marketing in the Romanian private ophthalmologic services by using structural equation modeling...
July 2017: Romanian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29444679/understanding-perceived-availability-and-importance-of-tobacco-control-interventions-to-inform-european-adoption-of-a-uk-economic-model-a-cross-sectional-study
#20
Puttarin Kulchaitanaroaj, Zoltán Kaló, Robert West, Kei Long Cheung, Silvia Evers, Zoltán Vokó, Mickael Hiligsmann, Hein de Vries, Lesley Owen, Marta Trapero-Bertran, Reiner Leidl, Subhash Pokhrel
BACKGROUND: The evidence on the extent to which stakeholders in different European countries agree with availability and importance of tobacco-control interventions is limited. This study assessed and compared stakeholders' views from five European countries and compared the perceived ranking of interventions with evidence-based ranking using cost-effectiveness data. METHODS: An interview survey (face-to-face, by phone or Skype) was conducted between April and July 2014 with five categories of stakeholders - decision makers, service purchasers, service providers, evidence generators and health promotion advocates - from Germany, Hungary, the Netherlands, Spain, and the United Kingdom...
February 14, 2018: BMC Health Services Research
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