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https://www.readbyqxmd.com/read/28728089/volumetric-and-morphological-characteristics-of-the-hippocampus-are-associated-with-progression-to-schizophrenia-in-patients-with-first-episode-psychosis
#1
R Sauras, A Keymer, A Alonso-Solis, A Díaz, C Molins, F Nuñez, M Rabella, A Roldán, E Grasa, E Alvarez, M J Portella, I Corripio
BACKGROUND: Abnormalities in the hippocampus have been implicated in the pathophysiology of psychosis. However, it is still unclear whether certain abnormalities are a pre-existing vulnerability factor, a sign of disease progression or a consequence of environmental factors. We hypothesized that first-episode psychosis patients who progress to schizophrenia after one year of follow up will display greater volumetric and morphological changes from the very beginning of the disorder. METHODS: We studied the hippocampus of 41 patients with a first-episode psychosis and 41 matched healthy controls...
July 5, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28721722/pillar-5-arene-based-supramolecular-plasmonic-thin-films-for-label-free-quantitative-and-multiplex-sers-detection
#2
Verónica Montes García, Borja Gómez-González, Diego M Solís, Jose M Taboada, Norman Jiménez Otero, Jacobo de Uña-Álvarez, Fernando Obelleiro, Luis García-Río, Jorge Perez-Juste, Isabel Pastoriza-Santos
Novel plasmonic thin films based on electrostatic layer-by-layer (LbL) deposition of citrate-stabilized Au nanoparticles (NPs) and ammonium pillar[5]arene (AP[5]A) has been developed. The supramolecular-induced LbL assembly of the plasmonic nanoparticles yields to the formation of controlled hot-spots with uniform interparticle distances. At the same time this strategy allows to modulate the density and dimensions of the Au aggregates, and therefore the optical response, on the thin film with the number of AuNP-AP[5]A deposition cycles...
July 19, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28716300/the-effect-of-training-level-on-complications-after-free-flap-surgery-of-the-head-and-neck
#3
Jacob S Brady, Meghan M Crippen, Andrey Filimonov, Neil V Nadpara, Jean Anderson Eloy, Soly Baredes, Richard Chan Woo Park
OBJECTIVES: Analyze postoperative complications after free flap surgery based on PGY training level. METHODS: Data on free flap surgeries of the head and neck performed from 2005 to 2013 was collected from the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) database. Cases identifying the status of resident participation in the surgery and the PGY level were included. RESULTS: There were 582 cases with primary surgeon data available...
June 2, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28714508/gold-glyconanoparticles-coupled-to-listeriolysin-o-91-99-peptide-serve-as-adjuvant-therapy-against-melanoma
#4
R Calderon-Gonzalez, H Terán-Navarro, I García, M Marradi, D Salcines-Cuevas, S Yañez-Diaz, A Solis-Angulo, E Frande-Cabanes, M C Fariñas, A Garcia-Castaño, J Gomez-Roman, S Penades, F Rivera, J Freire, C Álvarez-Domínguez
Dendritic cell-based (DC-based) vaccines are promising immunotherapies for cancer. However, several factors, such as the lack of efficient targeted delivery and the sources and types of DCs, have limited the efficacy of DCs and their clinical potential. We propose an alternative nanotechnology-based vaccine platform with antibacterial prophylactic abilities that uses gold glyconanoparticles coupled to listeriolysin O 91-99 peptide (GNP-LLO91-99), which acts as a novel adjuvant for cancer therapy. GNP-LLO91-99, when used to vaccinate mice, exhibited dual antitumour activities, namely, the inhibition of tumour migration and growth and adjuvant activity for recruiting and activating DCs, including those from melanoma patients...
July 17, 2017: Nanoscale
https://www.readbyqxmd.com/read/28709956/activation-of-human-gonadotropin-releasing-hormone-receptor-promotes-down-regulation-of-arhgap18-and-regulates-the-cell-invasion-of-mda-mb-231%C3%A2-cells
#5
Arturo Aguilar-Rojas, Guadalupe Maya-Núñez, Maira Huerta-Reyes, Marco Allán Pérez-Solis, Raúl Silva-García, Nancy Guillén, Jean-Christophe Olivo-Marin
The Gonadotropin-Releasing Hormone Receptor (GnRHR) is expressed mainly in the gonadotrope membrane of the adenohypophysis and its natural ligand, the Gonadotropin-Releasing Hormone (GnRH), is produced in anterior hypothalamus. Furthermore, both molecules are also present in the membrane of cells derived from other reproductive tissues such as the breast, endometrium, ovary, and prostate, as well as in tumors derived from these tissues. The functions of GnRH receptor and its hormone in malignant cells have been related with the decrease of proliferation and the invasiveness of those tumors however, little is known about the molecules associated with the signaling pathways regulated by both molecules in malignant cells...
July 11, 2017: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/28709859/recurrent-cardiac-fibroelastoma-is-it-really-a-benign-tumor
#6
Belén Díaz-Antón, Ángel González Pinto, Francisco Javier Parra Jiménez, Gregorio Cuerpo Caballero, Francisco Pérez Rodríguez, Jorge Solís Martín
No abstract text is available yet for this article.
July 11, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28709855/subcutaneous-edema-in-juvenile-dermatomyositis
#7
Alfonso Ragnar Torres Jiménez, Eunice Solís-Vallejo, Adriana Ivonne Céspedes-Cruz, Magdalena Sánchez-Uribe
No abstract text is available yet for this article.
July 11, 2017: Reumatología Clinica
https://www.readbyqxmd.com/read/28709619/umbilicated-papules-on-the-elbows-of-a-woman-with-systemic-vasculitis
#8
C Lloret-Ruiz, N Barrado-Solís, E Quecedo-Estébanez
No abstract text is available yet for this article.
July 11, 2017: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/28708609/evaluation-of-nutrients-removal-no3-n-nh3-n-and-po4-p-with-chlorella-vulgaris-pseudomonas-putida-bacillus-cereus-and-a-consortium-of-these-microorganisms-in-the-treatment-of-wastewater-effluents
#9
Abril Gómez-Guzmán, Sergio Jiménez-Magaña, A Suggey Guerra-Rentería, César Gómez-Hermosillo, F Javier Parra-Rodríguez, Sergio Velázquez, Blanca Rosa Aguilar-Uscanga, Josue Solis-Pacheco, Orfil González-Reynoso
In this research removal of NH3-N, NO3-N and PO4-P nutrients from municipal wastewater was studied, using Chlorella vulgaris, Pseudomonas putida, Bacillus cereus and an artificial consortium of them. The objective is to analyze the performance of these microorganisms and their consortium, which has not been previously studied for nutrient removal in municipal wastewater. A model wastewater was prepared simulating the physicochemical characteristics found at the wastewater plant in Chapala, Mexico. Experiments were carried out without adding an external carbon source...
July 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28707727/in-vitro-renin-angiotensin-system-inhibition-and-in-vivo-antihypertensive-activity-of-peptide-fractions-from-lima-bean-phaseolus-lunatus-l
#10
Norma A Ciau-Solís, Juan J Acevedo-Fernández, David Betancur-Ancona
BACKGROUND: The renin-angiotensin system is key in the physiopathology of arterial hypertension because it converts angiotensin I, via angiotensin I-converting enzyme (ACE), into angiotensin II. In vitro analyses were done of the ACE-inhibitory and renin-inhibitory activities of peptide fractions isolated by enzymatic hydrolysis of Lima bean (Phaseolus lunatus) protein. Antihypertensive activity was confirmed in vivo using a rat model. RESULTS: Lima bean protein was hydrolyzed with one of two sequential enzymatic systems (pepsin-pancreatin or Alcalase®-Flavourzyme®)...
July 14, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28706533/inhibition-of-histone-h3k9-methylation-by-bix-01294-promotes-stress-induced-microspore-totipotency-and-enhances-embryogenesis-initiation
#11
Eduardo Berenguer, Ivett Bárány, María-Teresa Solís, Yolanda Pérez-Pérez, María C Risueño, Pilar S Testillano
Microspore embryogenesis is a process of cell reprogramming, totipotency acquisition and embryogenesis initiation, induced in vitro by stress treatments and widely used in plant breeding for rapid production of doubled-haploids, but its regulating mechanisms are still largely unknown. Increasing evidence has revealed epigenetic reprogramming during microspore embryogenesis, through DNA methylation, but less is known about the involvement of histone modifications. In this study, we have analyzed the dynamics and possible role of histone H3K9 methylation, a major repressive modification, as well as the effects on microspore embryogenesis initiation of BIX-01294, an inhibitor of histone methylation, tested for the first time in plants, in Brassica napus and Hordeum vulgare...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28699577/sphingobacteriumsoli-sp-nov-isolated-from-soil
#12
Yu-Song Fu, Firasat Hussain, Neeli Habib, Inam Ullah Khan, Xiao Chu, Yan-Qing Duan, Xiao-Yang Zhi, Xing Chen, Wen-Jun Li
A Gram-stain-negative, strictly aerobic, rod-shaped, non-motile, non-spore-forming bacterial strain, designated YIM X0211T, was isolated from a soil sample of Shiling County, Yunnan Province, south-west China. The new isolate was characterized taxonomically by using a polyphasic approach. The strain grew optimally at 30 °C, at pH 7.0 and with 0-3 % (w/v) NaCl. It was positive for catalase and oxidase but negative for H2S production. Comparative 16S rRNA gene sequence analysis showed that strain YIM X0211T fell within the cluster comprising Sphingobacterium species and clustered with Sphingobacterium mizutaii DSM 11724T (97...
July 12, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28699565/household-costs-of-dengue-illness-secondary-outcomes-from-a-randomised-controlled-trial-of-dengue-prevention-in-guerrero-state-mexico
#13
José Legorreta-Soberanis, Sergio Paredes-Solís, Arcadio Morales-Pérez, Elizabeth Nava-Aguilera, Felipe René Serrano-de Los Santos, Diana Lisseth Dimas-Garcia, Robert J Ledogar, Anne Cockcroft, Neil Andersson
BACKGROUND: Dengue is a serious public health problem with an important economic impact. This study used data from a cluster randomised controlled trial of community mobilisation for dengue prevention to estimate the household costs of treatment of dengue illness. It examined the economic impact of the trial intervention in the three coastal regions of Mexico's Guerrero State. METHODS: The 2010 baseline survey covered households in a random sample of 90 clusters in the coastal regions; the clusters were randomly allocated to intervention or control and re-surveyed in 2012...
May 30, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28699563/the-women-made-it-work-fuzzy-transitive-closure-of-the-results-chain-in-a-dengue-prevention-trial-in-mexico
#14
Neil Andersson, Mario Beauchamp, Elizabeth Nava-Aguilera, Sergio Paredes-Solís, Mateja Šajna
BACKGROUND: A modified theory of planned behaviour (acronym CASCADA) proposes that Conscious knowledge precedes a change in Attitude, which in turn precedes positive deviations from negative Subjective norms, intention to Change, perception of Agency to change, Discussion of possible action, and Action itself. We used this as a results chain to investigate gender-specific behaviour dynamics in chemical-free dengue prevention. METHODS: Secondary analysis of the Mexican arm of a cluster randomised controlled trial used household survey data on intermediate outcomes of dengue prevention behaviour...
May 30, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28699562/which-green-way-description-of-the-intervention-for-mobilising-against-aedes-aegypti-under-difficult-security-conditions-in-southern-mexico
#15
REVIEW
Arcadio Morales-Perez, Elizabeth Nava-Aguilera, José Legorreta-Soberanis, Sergio Paredes-Solís, Alejandro Balanzar-Martínez, Felipe René Serrano-de Los Santos, Claudia Erika Ríos-Rivera, Jaime García-Leyva, Robert J Ledogar, Anne Cockcroft, Neil Andersson
BACKGROUND: Community mobilisation for prevention requires engagement with and buy in from those communities. In the Mexico state of Guerrero, unprecedented social violence related to the narcotics trade has eroded most community structures. A recent randomised controlled trial in 90 coastal communities achieved sufficient mobilisation to reduce conventional vector density indicators, self-reported dengue illness and serologically proved dengue virus infection. METHODS: The Camino Verde intervention was a participatory research protocol promoting local discussion of baseline evidence and co-design of vector control solutions...
May 30, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28699560/dengue-occurrence-relations-and-serology-cross-sectional-analysis-of-results-from-the-guerrero-state-mexico-baseline-for-a-cluster-randomised-controlled-trial-of-community-mobilisation-for-dengue-prevention
#16
Elizabeth Nava-Aguilera, Arcadio Morales-Pérez, Alejandro Balanzar-Martínez, Ofelia Rodríguez-Ramírez, Abel Jiménez-Alejo, Miguel Flores-Moreno, David Gasga-Salinas, José Legorreta-Soberanis, Sergio Paredes-Solís, Pedro Antonio Morales-Nava, María de Lourdes Soto-Ríos, Robert J Ledogar, Joséfina Coloma, Eva Harris, Neil Andersson
BACKGROUND: The Mexican arm of the Camino Verde trial of community mobilisation for dengue prevention covered three coastal regions of Guerrero state: Acapulco, Costa Grande and Costa Chica. A baseline cross-sectional survey provided data for community mobilisation and for adapting the intervention design to concrete conditions in the intervention areas. METHODS: Trained field teams constructed community profiles in randomly selected clusters, based on observation and key informant interviews...
May 30, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28699559/aedes-aegypti-breeding-ecology-in-guerrero-cross-sectional-study-of-mosquito-breeding-sites-from-the-baseline-for-the-camino-verde-trial-in-mexico
#17
Arcadio Morales-Pérez, Elizabeth Nava-Aguilera, Alejandro Balanzar-Martínez, Antonio Juan Cortés-Guzmán, David Gasga-Salinas, Irma Esther Rodríguez-Ramos, Alba Meneses-Rentería, Sergio Paredes-Solís, José Legorreta-Soberanis, Felipe Gil Armendariz-Valle, Robert J Ledogar, Anne Cockcroft, Neil Andersson
BACKGROUND: Understanding the breeding patterns of Aedes aegypti in households and the factors associated with infestation are important for implementing vector control. The baseline survey of a cluster randomised controlled trial of community mobilisation for dengue prevention in Mexico and Nicaragua collected information about the containers that are the main breeding sites, identified possible actions to reduce breeding, and examined factors associated with household infestation. This paper describes findings from the Mexican arm of the baseline survey...
May 30, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28699554/coverage-and-beliefs-about-temephos-application-for-control-of-dengue-vectors-and-impact-of-a-community-based-prevention-intervention-secondary-analysis-from-the-camino-verde-trial-in-mexico
#18
José Legorreta-Soberanis, Sergio Paredes-Solís, Arcadio Morales-Pérez, Elizabeth Nava-Aguilera, Felipé René Serrano de Los Santos, Belén Madeline Sánchez-Gervacio, Robert J Ledogar, Anne Cockcroft, Neil Andersson
BACKGROUND: Temephos in domestic water containers remains a mainstay of Latin American government programmes for control of Aedes aegypti and associated illnesses, including dengue. There is little published evidence about coverage of routine temephos programmes. A cluster randomised controlled trial of community mobilisation in Mexico and Nicaragua reduced vector indices, dengue infection, and clinical dengue cases. Secondary analysis from the Mexican arm of the trial examined temephos coverage and beliefs, and the impact of the trial on these outcomes...
May 30, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28699552/assessing-the-effects-of-interventions-for-aedes-aegypti-control-systematic-review-and-meta-analysis-of-cluster-randomised-controlled-trials
#19
Víctor Alvarado-Castro, Sergio Paredes-Solís, Elizabeth Nava-Aguilera, Arcadio Morales-Pérez, Lidia Alarcón-Morales, Norma Alejandra Balderas-Vargas, Neil Andersson
BACKGROUND: The Aedes aegypti mosquito is the vector for dengue fever, yellow fever, chikungunya, and zika viruses. Inadequate vector control has contributed to persistence and increase of these diseases. This review assesses the evidence of effectiveness of different control measures in reducing Aedes aegypti proliferation, using standard entomological indices. METHODS: A systematic search of Medline, Ovid, BVS, LILACS, ARTEMISA, IMBIOMED and MEDIGRAPHIC databases identified cluster randomised controlled trials (CRCTs) of interventions to control Aedes aegypti published between January 2003 and October 2016...
May 30, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28699550/household-costs-for-personal-protection-against-mosquitoes-secondary-outcomes-from-a-randomised-controlled-trial-of-dengue-prevention-in-guerrero-state-mexico
#20
José Legorreta-Soberanis, Sergio Paredes-Solís, Arcadio Morales-Pérez, Elizabeth Nava-Aguilera, Felipe René Serrano-de Los Santos, Belén Madeline Sánchez-Gervacio, Robert J Ledogar, Anne Cockcroft, Neil Andersson
BACKGROUND: Dengue is a serious public health issue that affects households in endemic areas in terms of health and also economically, imposing costs for prevention and treatment of cases. The Camino Verde cluster-randomised controlled trial in Mexico and Nicaragua assessed the impact of evidence-based community engagement in dengue prevention. The Mexican arm of the trial was conducted in 90 randomly selected communities in three coastal regions of Guerrero State. This study reports an analysis of a secondary outcome of the trial: household use of and expenditure on anti-mosquito products...
May 30, 2017: BMC Public Health
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