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Peritoneal Dialysis, CAPD vs APD

Bengt Rippe, Carl M Öberg
♦ Background: A modified version of automated peritoneal dialysis (APD) using not only variable dwell times but also variable fill volumes has been tested against conventional APD (cAPD) with fixed dwell volumes in a randomized controlled clinical study. The results have indicated that the modified schedule for APD, denoted adapted APD (aAPD), can lead to improved small solute clearances, and, above all, a markedly increased sodium removal (NaR). To theoretically test these results, we have modeled aAPD vs cAPD in computer simulations using the 3-pore model (TPM)...
February 4, 2016: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
Ricardo L M Losso, Gisele R Minhoto, Miguel C Riella
Sleep disorders for patients on dialysis are significant causes of a poorer quality of life and increased morbidity and mortality. No study has evaluated patients undergoing automated peritoneal dialysis (APD) to assess their sleep disorders compared to hemodialysis (HD) and continuous ambulatory peritoneal dialysis (CAPD). A total of 166 clinically stable patients who had been on dialysis for at least 3 months were randomly selected for the study and divided into HD, CAPD or APD. Socio-demographic, clinical and laboratory parameters and self-administered questionnaires were collected for the investigation of insomnia, restless legs syndrome (RLS), bruxism, rapid eye movement sleep behavior disorder, excessive daytime sleepiness (EDS), obstructive sleep apnea syndrome (OSAS), sleepwalking, sleep hygiene, depression and anxiety...
February 2015: International Urology and Nephrology
J Pedro Teixeira, Sara A Combs, Isaac Teitelbaum
Due to ongoing limitations in the availability and timeliness of kidney transplantation, most patients with end-stage renal disease (ESRD) require some form of dialysis during their lifetime. Worldwide, ESRD patients most commonly receive hemodialysis (HD) or one of two forms of peritoneal dialysis (PD), continuous ambulatory PD (CAPD) or automated PD (APD). In this review, we analyze the data available from the last several decades on overall survival associated with HD as compared to PD as well as with CAPD compared to APD...
January 2015: Clinical Nephrology
Nuh Ataş, Yasemin Erten, Gülay Ulusal Okyay, Salih Inal, Salih Topal, Kürşad Öneç, Ahmet Akyel, Bülent Çelik, Yusuf Tavil, Musa Bali, Turgay Arınsoy
Hypertension, non-dipper blood pressure (BP) pattern and decrease in daily urine output have been associated with left ventricular hypertrophy (LVH) in peritoneal dialysis (PD) patients. However, there is lack of data regarding the impact of different PD regimens on these factors. We aimed to investigate the impact of circadian rhythm of BP on LVH in end-stage renal disease patients using automated peritoneal dialysis (APD) or continuous ambulatory peritoneal dialysis (CAPD) modalities. Twenty APD (7 men, 13 women) and 28 CAPD (16 men, 12 women) patients were included into the study...
June 2014: Therapeutic Apheresis and Dialysis
Sunny Eloot, Raymond Vanholder, Clement Dequidt, Wim Van Biesen
UNLABELLED:AIM: In this study, we investigated, and this for the different classes of uremic toxins, whether increasing dialysate volume by shifting from continuous ambulatory peritoneal dialysis (CAPD) to higher volume automated peritoneal dialysis (APD) increases total solute clearance. ♦ METHODS: Patients on peritoneal dialysis were randomized in a cross-over design to one 24-hour session of first a CAPD regimen (3*2 L of Physioneal 1...
July 2015: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
César Remón-Rodríguez, Pedro Quirós-Ganga, José Portolés-Pérez, Carmina Gómez-Roldán, Alfonso Miguel-Carrasco, Mercè Borràs-Sans, Ana Rodríguez-Carmona, Miguel Pérez-Fontán, J Emilio Sánchez-Álvarez, Carmen Rodríguez Suárez
INTRODUCTION AND OBJECTIVES: There is currently no registry that gives a complete and overall view of the peritoneal dialysis (PD) situation in Spain. However, a report on PD in Spain was developed for various conferences and meetings over several years from data provided by each registry in the autonomous communities and regions. The main objective of this study is to analyse this data in aggregate and comparatively to obtain a representative sample of the Spanish population on PD in recent years, in order that analysis and results in terms of demographic data, penetration of the technique, geographical differences, incidence and prevalence, technical aspects, intermediate indicators, comorbidity, and outcomes such as patient and technique survival may be extrapolated to the whole country...
2014: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
Chan Ho Kim, Hyung Jung Oh, Mi Jung Lee, Young Eun Kwon, Yung Ly Kim, Ki Heon Nam, Kyoung Sook Park, Seong Yeong An, Kwang Il Ko, Hyang Mo Koo, Fa Mee Doh, Seung Hyeok Han, Tae-Hyun Yoo, Beom Seok Kim, Shin-Wook Kang, Kyu Hun Choi
PURPOSE: The effect of different peritoneal dialysis (PD) modalities on the decline in residual renal function (RRF) is unclear due to inconsistencies among studies. In particular, the effect of automated peritoneal dialysis (APD) modalities [continuous cyclic peritoneal dialysis (CCPD) and nightly intermittent peritoneal dialysis (NIPD)] on RRF has not been examined in a large cohort. MATERIALS AND METHODS: We conducted a single-center retrospective study to investigate the association between PD modalities and decline in RRF in 142 incident PD patients [34 on CCPD, 36 on NIPD, and 72 on continuous ambulatory peritoneal dialysis (CAPD)]...
January 2014: Yonsei Medical Journal
Laura Cortés-Sanabria, Carlos A Paredes-Ceseña, Rebeca M Herrera-Llamas, Yolanda Cruz-Bueno, Herman Soto-Molina, Leonardo Pazarín, Margarita Cortés, Héctor R Martínez-Ramírez
BACKGROUND AND AIMS: The use of automated peritoneal dialysis (APD) is increasing compared to continuous ambulatory peritoneal dialysis (CAPD). Surprisingly, little data about health benefits and cost of APD exist, and virtually no information comparing the cost-utility between CAPD and APD is available. We undertook this study to evaluate and compare the health-related quality of life (HRQOL) and cost-utility indexes in patients on CAPD vs. APD METHODS: This was a prospective cohort of patients initiating dialysis (2008-2009)...
November 2013: Archives of Medical Research
Laura Cortés-Sanabria, Brenda E Rodríguez-Arreola, Victor R Ortiz-Juárez, Herman Soto-Molina, Leonardo Pazarín-Villaseñor, Héctor R Martínez-Ramírez, Alfonso M Cueto-Manzano
OBJECTIVE: We set out to estimate the direct medical costs (DMCs) of peritoneal dialysis (PD) and to compare the DMCs for continuous ambulatory PD (CAPD) and automated PD (APD). In addition, DMCs according to age, sex, and the presence of peritonitis were evaluated. METHODS: Our retrospective cohort analysis considered patients initiating PD, calculating 2008 costs and, for comparison, updating the results for 2010. The analysis took the perspective of the Mexican Institute of Social Security, including outpatient clinic and emergency room visits, dialysis procedures, medications, laboratory tests, hospitalizations, and surgeries...
November 2013: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
Bonnie Ching-Ha Kwan, Kai-Ming Chow, Terry King-Wing Ma, Vincent Yu, Man-Ching Law, Chi-Bon Leung, Philip Kam-Tao Li, Cheuk-Chun Szeto
AIM: To compare the clinical outcome between continuous ambulatory peritoneal dialysis (CAPD) and automated peritoneal dialysis (APD) in specific subgroups of patients. METHODS: We reviewed the clinical outcome of 90 consecutive incident APD patients and 180 CAPD patients in our centre. RESULTS: The median follow up was 21.9 months (inter-quartile range, 9.5 to 46.5 months). The APD group was younger and had a lower Charlson's score than the CAPD group...
May 2013: Nephrology
Costas Fourtounas, Periklis Dousdampanis, Andreas Hardalias, Jannis G Vlachojannis
Continuous ambulatory peritoneal dialysis (CAPD) has been considered as a more efficient modality for sodium removal than automated peritoneal dialysis (APD), due to the longer dwell times and the sodium sieving phenomenon. However, because studies regarding sodium removal in peritoneal dialysis (PD) report rather controversial results and carry various methodological flaws, it remains uncertain whether they offer enough significant information regarding PD prescription and therapy. The aim of the present observational cross-sectional study was to evaluate the impact of the optimal prescription of CAPD and APD, regarding solute clearances and daily ultrafiltrate, on daily sodium removal...
July 2013: Artificial Organs
Alessandro Domenici, Luca Scabbia, Francesca Sivo, Clorinda Falcone, Giorgio Punzo, Paolo Menè
In a comprehensive evaluation of dialysis adequacy, major attention has been recently paid to fluid and Na balance. Removal of Na has been reported to be significantly poorer with automated peritoneal dialysis (APD) than with continuous ambulatory peritoneal dialysis. Only limited data on Na removal with tidal APD have been published. We analyzed peritoneal Na mass balance in 122 separate nightly tidal APD sessions performed by 7 peritonitis-free, clinically stable, patients with negligible residual renal function (< 100 mL urine daily)...
2012: Advances in Peritoneal Dialysis
Wen-Hung Huang, Cheng-Chieh Hung, Chih-Wei Yang, Jeng-Yi Huang
Peritoneal dialysis (PD) is characterized by a slow continuous removal of solutes. Traditionally, dialysis adequacy is quantified by referring to the kinetics of urea nitrogen (UN) and creatinine (Cr) clearance. The efficacy of middle molecular substances and protein-bound solutes as markers for peritoneal dialysis adequacy is not clear. The aim of this cross-sectional study was to investigate correlations between the clearance of indoxyl sulfate (IS), p-cresyl sulfate (PCS), UN, and Cr in the peritoneum and kidneys and to compare the overall clearances of IS and PCS between non-anuric and anuric groups in PD patients...
August 2012: Therapeutic Apheresis and Dialysis
Wieneke M Michels, Marion Verduijn, Alena Parikova, Elisabeth W Boeschoten, Dirk G Struijk, Friedo W Dekker, Raymond T Krediet
BACKGROUND AND OBJECTIVES: In automated peritoneal dialysis (APD), a patient's peritoneal membrane is more intensively exposed to fresh dialysate than it is in continuous ambulatory peritoneal dialysis (CAPD). Our aim was to study, in incident peritoneal dialysis (PD) patients, the influence of APD-compared with that of CAPD-on peritoneal transport over 4 years. DESIGN, SETTING, PARTICIPANTS, AND MEASUREMENTS: Patients were included if at least 2 annual standard permeability analyses (SPAs) performed with 3...
November 2012: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
Giancarlo Marinangeli, Gianfranca Cabiddu, Loris Neri, Giusto Viglino, Roberto Russo, Ugo Teatini
BACKGROUND: To understand how peritoneal dialysis (PD) was being used in Italy in 2005 and 2008, a census of all centers was carried out. METHODS: In 2005 and 2008, data were collected from, respectively, 222 and 223 centers, with respect to 4432 and 4094 prevalent patients. RESULTS: In the two periods, the PD incidence remained stable (24.3% vs 22.9%), varying from center to center. Continuous ambulatory PD (CAPD) was the main initial method (55%), but APD was more widespread among prevalent patients (53%)...
September 2012: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
Talerngsak Kanjanabuch, Nopadol Puttipittayathorn, Asada Leelahavanichkul, Songkiat Lieusuwan, Pisut Katavetin, Nanta Mahatanan, Kanda Sriudom, Thanit Chirananthavat, Nisa Thongbor, Somchai Eiam-Ong
OBJECTIVE: Automated peritoneal dialysis (APD) becomes the first option for peritoneal dialysis, nowadays overtaking continuous ambulatory peritoneal dialysis (CAPD) in many countries. The comparison of peritoneal membrane alteration in CAPD and APD is inconclusive. The authors therefore compared the peritoneal membrane changes in patients undergoing CAPD and APD. MATERIAL AND METHOD: In naive end stage renal disease patients, the choice of PD modes (CAPD or APD) was dependent on the patient's decision...
September 2011: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
Gowrie Balasubramanian, Khadija McKitty, Stanley L-S Fan
BACKGROUND: There is a wide disparity in the use of automated peritoneal dialysis (APD) or continuous ambulatory peritoneal dialysis (CAPD) in the UK. This may be due to a perceived quality of life and technique survival advantage with APD, although evidence is lacking. METHODS: We conducted a single-centre retrospective study of incident end-stage renal disease initiating APD and CAPD with data collected prospectively over 5 years. PD modality was based on patient preference...
May 2011: Nephrology, Dialysis, Transplantation
Konstadina Griva, Andrew Davenport, Michael Harrison, Stanton Newman
OBJECTIVES: Depressive symptoms are common among patients with end-stage renal disease (ESRD). In order to better understand what factors influence these symptoms, we examined the impact of illness and treatment cognitions on emotional adjustment and the influence of dialysis modality (hospital- vs. home-based dialysis) on this relationship. METHODS: A cross-sectional sample of 145 ESRD patients on four different dialysis modalities [hospital hemodialysis (HD), n=52; home HD, n=25; continuous ambulatory peritoneal dialysis (CAPD), n=45; automated PD (APD), n=23] completed the Illness Perceptions Questionnaire, the Illness Effects Questionnaire, the Treatment Effects Questionnaire, and the Beck Depression Inventory...
October 2010: Journal of Psychosomatic Research
Yu-Jen Su, Chien-Te Lee, Feng-Rong Chuang, Chih-Hsiung Lee, Yi-Chun Wang, Ben-Chung Cheng, Kuo-Tai Hsu, Jin-Bor Chen
AIMS: To date, there is convincing evidence for the preservation of residual renal function (RRF) in peritoneal dialysis (PD) patients; however, substantially variable data exist on the incidence rate of infectious complications and the decline of RRF for automated peritoneal dialysis (APD) and continuous ambulatory peritoneal dialysis (CAPD). The purpose of our study was to investigate the relative merits or demerits of APD compared with CAPD. METHODS: From November 1998 to November 2007, we retrospectively reviewed 32 patients on APD and 140 patients on CAPD...
2010: Renal Failure
M G Garcia-Lopes, R G Agliussi, C M Avesani, S R Manfredi, A P Bazanelli, M A Kamimura, S A Draibe, L Cuppari
Our objective was to determine if automated peritoneal dialysis (APD) leads to changes in nutritional parameters of patients treated by continuous ambulatory peritoneal dialysis (CAPD). Twenty-six patients (15 males; 50.5 +/- 14.3 years) were evaluated during CAPD while training for APD and after 3 and 6 months of APD. Body fat was assessed by the sum of skinfold thickness and the other body compartments were assessed by bioelectrical impedance. During the 6-month follow-up, 12 patients gained more than 1 kg (GW group), 8 patients lost more than 1 kg (LW group), and 6 patients maintained body weight (MW group)...
December 2008: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
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