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https://www.readbyqxmd.com/read/28432506/elective-colectomy-for-diverticulitis-in-transplant-patients-is-it-worth-the-risk
#1
Janet T Lee, Steve Skube, Genevieve B Melton, Mary R Kwaan, Christine C Jensen, Robert D Madoff, Wolfgang B Gaertner
BACKGROUND: The aim of this study was to determine morbidity and mortality for transplant patients undergoing elective colectomy for diverticulitis and determine the impact of recurrent diverticulitis on postoperative complications. METHODS: We identified transplant recipients that underwent elective colectomy for diverticulitis between 2000 and 2015 at a tertiary care institution. Patient and procedure variables, postoperative complications, length of stay, 30-day readmission, and mortality were identified through retrospective chart review...
April 21, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28429952/rare-cases-imitating-acute-appendicitis-three-case-reports-and-a-review-of-literature
#2
L Kunovsky, Z Kala, L Mitas, V Can, J Dolina, E Nemcová, L Klvacova, T Gajdosova, I Penka
Acute appendicitis with its characteristic clinical course is one of the most common diagnoses that require urgent surgery. The following three case reports present patients with symptoms typical of acute appendicitis which was, however, not confirmed intraoperatively. Preoperative CT or MRI were not requested because symptoms clearly indicated acute appendicitis. The first case describes a male patient with right-sided diverticulitis, the second case report involves a pregnant woman in 33rd week of gestation with right adnexal torsion due to a dermoid cyst, and in the last report, a case of spontaneous perforation of appendiceal mucinous neoplasm is presented...
2017: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://www.readbyqxmd.com/read/28428656/what-radiologists-should-know-about-tomographic-evaluation-of-acute-diverticulitis-of-the-colon
#3
Aline de Araújo Naves, Giuseppe D'Ippolito, Luis Ronan Marquez Ferreira Souza, Sílvia Portela Borges, Glênio Moraes Fernandes
Acute diverticulitis of the colon is a common indication for computed tomography, and its diagnosis and complications are essential to determining the proper treatment and establishing the prognosis. The adaptation of the surgical classification for computed tomography has allowed the extent of intestinal inflammation to be established, the computed tomography findings correlating with the indication for treatment. In addition, computed tomography has proven able to distinguish among the main differential diagnoses of diverticulitis...
March 2017: Radiologia Brasileira
https://www.readbyqxmd.com/read/28424119/the-changing-epidemiology-of-diverticulitis-in-the-united-states
#4
Trevor Teetor, Ben Palachick, Rod Grim, Ted Bell, Jen Martin, David Blumberg, Kamran Khan, Vanita Ahuja
No abstract text is available yet for this article.
April 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28416195/pitavastatin-versus-pravastatin-in-adults-with-hiv-1-infection-and-dyslipidaemia-intrepid-12-week-and-52-week-results-of-a-phase-4-multicentre-randomised-double-blind-superiority-trial
#5
Judith A Aberg, Craig A Sponseller, Douglas J Ward, Vladimir A Kryzhanovski, Stuart E Campbell, Melanie A Thompson
BACKGROUND: People living with HIV-1 infection are at greater risk for cardiovascular disease than seronegative adults. Treatment of dyslipidaemia with statins has been challenging in people with HIV because of an increased potential for drug interactions due to competing cytochrome P450 metabolism between statins and commonly used antiretroviral agents. Neither pitavastatin nor pravastatin depend on cytochrome P450 for primary metabolism. We aimed to assess the safety and efficacy of pitavastatin versus pravastatin in adults with HIV and dyslipidaemia...
April 13, 2017: Lancet HIV
https://www.readbyqxmd.com/read/28409067/lemmel-syndrome-secondary-to-duodenal-diverticulitis-a-case-report
#6
Keyur Desai, Joshua D Wermers, Nebiyu Beteselassie
Lemmel syndrome occurs when a duodenal diverticulum causes obstructive jaundice due to a mechanical obstruction of the common bile duct. Additional pathophysiologic processes may also contribute to the development of Lemmel syndrome. These include duodenal diverticula causing dysfunction of the sphincter of Oddi as well as compression of the common bile duct by duodenal diverticula. It is uncommon for duodenal diverticulum to become inflamed. We report the case of a 25-year-old female presenting with unintentional weight loss and fatigue...
March 1, 2017: Curēus
https://www.readbyqxmd.com/read/28406778/appendicular-diverticulosis-with-appendicitis
#7
Syed Muhammad Hammad Alam
Appendicular diverticulosis is one of the very rare diseases which is also difficult to diagnose, especially clinically, due to its silent course and non-specific symptoms. It comes under the notation usually due to its complications like diverticulitis or perforation, but sometimes it also presents with acute appendicitis. This report describes a 44-year male patient who presented with the complain of right iliac fossa pain and was clinically diagnosed as acute appendicitis; but intraoperatively, it was found that the appendix also had diverticulosis along with appendicitis...
March 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28404009/when-is-elective-resection-after-acute-diverticulitis-reasonable
#8
Johannes Kurt Schultz
No abstract text is available yet for this article.
January 2017: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28404008/surgery-versus-conservative-management-for-recurrent-and-ongoing-left-sided-diverticulitis-direct-trial-an-open-label-multicentre-randomised-controlled-trial
#9
Bryan J M van de Wall, Marguerite A W Stam, Werner A Draaisma, R Stellato, Willem A Bemelman, Marja A Boermeester, Ivo A M J Broeders, Eric J Belgers, Boudewijn R Toorenvliet, Hubert A Prins, Esther C J Consten
BACKGROUND: Patients with recurrent or persisting complaints after an episode of left-sided diverticulitis are managed with either conservative measures or elective sigmoidectomy. To date, there are no data from randomised trials. We aimed to establish which treatment leads to a better quality of life for patients with diverticulitis. METHODS: We did an open-label, multicentre, randomised controlled trial (DIRECT trial) in 24 teaching and two academic hospitals in the Netherlands...
January 2017: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28403899/hepato-bronchial-fistula-secondary-to-perforated-sigmoid-diverticulitis-a-case-report
#10
Jun Sunny Yin, Shaylan Govind, Daniele Wiseman, Richard Inculet, Raymond Kao
BACKGROUND: Patients with diverticulitis are predisposed to hepatic abscesses via seeding through the portal circulation. Hepatic abscesses are well-documented sequelae of diverticulitis, however instances of progression to hepato-bronchial fistulization are rare. We present a case of diverticulitis associated with hepatic abscess leading to hepato-bronchial fistulization, which represents a novel disease course not yet reported in the literature. CASE PRESENTATION: A 61-year-old Caucasian man presented with a history of unintentional weight loss and dyspnea both at rest and with exertion...
April 13, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28401253/uncomplicated-acute-diverticulitis-identifying-risk-factors-for-severe-outcomes
#11
Rebekah Jaung, Malsha Kularatna, Jason P Robertson, Ryash Vather, David Rowbotham, Andrew D MacCormick, Ian P Bissett
BACKGROUND: The management of uncomplicated (Modified Hinchey Classification Ia) acute diverticulitis (AD) has become increasingly conservative, with a focus on symptomatic relief and supportive management. Clear criteria for patient selection are required to implement this safely. This retrospective study aimed to identify risk factors for severe clinical course in patients with uncomplicated AD. MATERIALS AND METHODS: Patients admitted to General Surgery at two New Zealand tertiary centres over a period of 18 months were included...
April 11, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28394790/laparoscopic-lavage-is-feasible-and-safe-for-the-treatment-of-perforated-diverticulitis-with-purulent-peritonitis-the-first-results-from-the-randomized-controlled-trial-dilala
#12
Cecilia Ponzano, Cristiano Germano Sigismondo Hüscher, Diletta Overi
No abstract text is available yet for this article.
May 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28393286/body-mass-index-and-physical-activity-and-the-risk-of-diverticular-disease-a-systematic-review-and-meta-analysis-of-prospective-studies
#13
REVIEW
Dagfinn Aune, Abhijit Sen, Michael F Leitzmann, Teresa Norat, Serena Tonstad, Lars J Vatten
PURPOSE: We conducted a systematic review and meta-analysis of prospective studies of the association between body mass index (BMI) and physical activity and diverticular disease risk. METHODS: PubMed and Embase databases were searched up to February 7, 2017. Summary relative risks and 95% confidence intervals (95% CIs) were calculated using a random effects model and nonlinear associations were modeled using fractional polynomial models. RESULTS: Six cohort studies of BMI and diverticular disease risk (28,915 cases, 1,636,777 participants) and five cohort studies of physical activity and diverticular disease risk (2080 cases, 147,869 participants) were included...
April 9, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28387885/retrospective-comparison-of-long-term-ten-day-month-rifaximin-or-mesalazine-in-prevention-of-relapse-in-acute-diverticulitis
#14
V Festa, S Spila Alegiani, F Chiesara, A Moretti, M Bianchi, A Dezi, G Traversa, M Koch
OBJECTIVE: Diverticular disease (DD) of the colon has an increasing burden on health services. The effectiveness of rifaximin for the treatment of DD, is not yet established. The aim of this study is to assess the impact of long-term treatment with rifaximin or mesalazine in a 10-day schedule for the prevention of recurrent diverticulitis. PATIENTS AND METHODS: This is a retrospective study. We identified all consecutive patients with DD and previous acute diverticulitis (AD) in our outpatients' database; 124 patients, were included...
March 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28383667/inactivation-of-jnk2-as-carcinogenic-factor-in-colitis-associated-and-sporadic-colorectal-carcinogenesis
#15
Wiebke Lessel, Andrew Silver, Doerthe Jechorek, Thomas Guenther, Friedrich Wilhelm Roehl, Thomas Kalinski, Albert Roessner, Angela Poehlmann-Nitsche
We recently reported that dysregulated c-Jun N-terminal kinases (JNK) activity causes defective cell cycle checkpoint control, inducing neoplastic transformation in a cellular ulcerative colitis (UC) model. In the quiescent chronic phase of UC, p-p54 JNK was down-regulated and p-p46 JNK was up-regulated. Both were up-regulated in the acute phase. Consequently, increased p21WAF1 and γ-H2AX, two JNK-regulated proteins, induced cell cycle arrest. Their down-regulation led to checkpoint override, causing increased proliferation and undetected DNA damage in quiescent chronic phase, all characteristics of tumorigenesis...
April 5, 2017: Carcinogenesis
https://www.readbyqxmd.com/read/28381939/laparoscopy-for-benign-diseases-of-the-colon
#16
REVIEW
Radhika Smith, David J Maron
Laparoscopic surgery has revolutionized the delivery of care to the surgical patient undergoing colorectal resection. Since the first laparoscopic-assisted colectomy in 1991, significant advances have been made in minimally invasive colorectal surgery. For many benign conditions, laparoscopic colectomy has been proven to be safe and effective, and in some instances superior when compared with open surgery. Complex laparoscopic resections such as those for diverticulitis and inflammatory bowel disease have also been shown to have equivalent outcomes when compared with open surgery...
April 2017: Clinics in Colon and Rectal Surgery
https://www.readbyqxmd.com/read/28378155/preservation-of-the-superior-rectal-artery-influence-of-surgical-technique-on-anastomotic-healing-and-postoperative-morbidity-in-laparoscopic-sigmoidectomy-for-diverticular-disease
#17
Maximilian Sohn, H J Schlitt, M Hornung, C Zülke, A Hochrein, C Moser, A Agha
PURPOSE: To evaluate the impact of superior rectal artery (SRA) sparing technique on anastomotic leakage in laparoscopic sigmoidectomy for diverticular disease. MATERIAL AND METHODS: A retrospective multicenter analysis of all patients undergoing laparoscopic sigmoid resection for diverticular disease between 2002 and 2015 was conducted. Data were recorded in three hospitals: University Hospital Regensburg, Marienhospital Gelsenkirchen, and Städtisches Klinikum München Bogenhausen...
April 4, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28376628/the-use-of-the-modified-neff-classification-in-the-management-of-acute-diverticulitis
#18
Laura Mora López, Roser Flores Clotet, Xavier Serra Aracil, Noemí Montes Ortega, Salvador Navarro Soto
INTRODUCTION: Acute diverticulitis (AD) is increasingly seen in Emergency services. The application of a reliable classification is vital for its safe and effective management. OBJECTIVE: To determine whether the combined use of the modified Neff radiological classification (mNeff) and clinical criteria (systemic inflammatory response syndrome [SIRS] and comorbidity) can ensure safe management of AD. MATERIAL AND METHODS: Prospective descriptive study in a population of patients diagnosed with AD by computerized tomography (CT)...
April 5, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28374561/distilling-data-from-dogma-the-management-of-diverticulitis-continues-to-evolve
#19
EDITORIAL
John P Burke
No abstract text is available yet for this article.
April 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/28371339/surgical-treatment-of-uncomplicated-diverticulitis-in-switzerland-comparison-of-population-based-data-over-two-time-periods
#20
Marco von Strauss Und Torney, Sarah Thommen, Salome Dell-Kuster, Henry Hoffmann, Rachel Rosenthal, James Young, Christoph Kettelhack
INTRODUCTION: The standard of care for acute uncomplicated diverticulitis used to be an elective colon resection after second or third episode. This practice was replaced by a more conservative and individualised approach. This study investigates current surgical practice in the treatment of acute uncomplicated diverticulitis in Switzerland. METHODS: Retrospective cross sectional analysis of all hospital admissions due to uncomplicated diverticulitis in Switzerland using prospectively collected data from the Swiss federal statistical office in two periods: 2004 to 2005 and 2010 to 2011...
March 29, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
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