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Coping Mechanism

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https://www.readbyqxmd.com/read/28432893/optimism-and-benefit-finding-in-parents-of-children-with-developmental-disabilities-the-role-of-positive-reappraisal-and-social-support
#1
Éadaoin Slattery, Jennifer McMahon, Stephen Gallagher
BACKGROUND: Researchers have consistently documented the relationship between optimism and benefit finding; however, there is a dearth of research on the psychological mechanisms mediating their association. AIM: This cross-sectional study sought to elucidate the mediating role of positive reappraisal and social support in the optimism-benefit finding relationship in parents caring for children with developmental disabilities by testing a parallel multiple mediation model...
April 19, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28432314/the-effect-of-acute-social-stress-on-the-recognition-of-facial-expression-of-emotions
#2
Camille Daudelin-Peltier, Hélène Forget, Caroline Blais, Andréa Deschênes, Daniel Fiset
This study investigates the effect of acute social stress on the recognition of facial expression of emotions in healthy young men. Participants underwent both a standardized psychosocial laboratory stressor (TSST-G) and a control condition. Then, they performed a homemade version of the facial expressions megamix. All six basic emotions were included in the task. First, our results show a systematic increase in the intensity threshold for disgust following stress, meaning that the participants' performance with this emotion was impaired...
April 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28431977/transcriptome-comparison-reveals-insights-into-muscle-response-to-hypoxia-in-blunt-snout-bream-megalobrama-amblycephala
#3
Bo-Xiang Chen, Shao-Kui Yi, Wei-Feng Wang, Yan He, Yan Huang, Ze-Xia Gao, Hong Liu, Wei-Min Wang, Huan-Ling Wang
The economic and biological significance of blunt snout bream (Megalobrama amblycephala) makes this species important to explore the underlying molecular mechanism of hypoxia response. In the present study, we compared the transcriptional responses to serious hypoxia in skeletal muscle among hypoxia tolerant (MT), sensitive (MS) and control (without hypoxia treatment, MC) M. amblycephala obtained according to the time difference of losing balance after hypoxia treatment. A total of 88,200,889 clean reads were generated and assembled into 44,493 unigenes...
April 18, 2017: Gene
https://www.readbyqxmd.com/read/28427825/molecular-mechanisms-of-the-yeast-adaptive-response-and-tolerance-to-stresses-encountered-during-ethanol-fermentation
#4
REVIEW
Choowong Auesukaree
During ethanol fermentation, yeast cells encounter various stresses including sugar substrates-induced high osmolarity, increased ethanol concentration, oxygen metabolism-derived reactive oxygen species (ROS), and elevated temperature. To cope with these fermentation-associated stresses, appropriate adaptive responses are required to prevent stress-induced cellular dysfunctions and to acquire stress tolerances. This review will focus on the cellular effects of these stresses, molecular basis of the adaptive response to each stress, and the cellular mechanisms contributing to stress tolerance...
April 17, 2017: Journal of Bioscience and Bioengineering
https://www.readbyqxmd.com/read/28426395/compassion-fatigue-and-compassion-satisfaction-in-hospice-social-work
#5
Sally B Pelon
As part of the interprofessional team of hospice caregivers, social workers are exposed to multiple stressors, both in their work with dying patients and their families and in functioning as professionals within rapidly changing health care organizations. Ongoing exposure to such stressors prompts concern about the emotional and psychological effect working with people who are dying may have on those who do it. Further, an understanding is needed regarding how hospice social workers interpret the costs and benefits of their work and how they cope with the dying and loss that pervade their everyday work lives...
April 20, 2017: Journal of Social Work in End-of-life & Palliative Care
https://www.readbyqxmd.com/read/28425747/early-change-in-coping-strategies-in-responsive-treatments-for-borderline-personality-disorder-a-mediation-analysis
#6
Ueli Kramer, Sabine Keller, Franz Caspar, Yves de Roten, Jean-Nicolas Despland, Stéphane Kolly
BACKGROUND: Difficulty in emotion regulation is a hallmark feature of patients with borderline personality disorder (BPD). Therefore, change in the frequency of certain patients' coping strategies-aiming at emotion regulation-are among the most promising mechanisms of change in treatments for BPD. In parallel, it was highlighted that therapist responsiveness significantly contributed to outcome across treatment approaches (Stiles, 2009). Based on a randomized controlled trial (Kramer et al...
May 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/28425584/changes-in-ciap2-survivin-and-bimel-expression-characterize-the-switch-from-autophagy-to-apoptosis-in-prolonged-starvation
#7
A Hay-Koren, S Bialik, V Levin-Salomon, A Kimchi
BACKGROUND: Autophagy is a catabolic process involving the engulfment of cytoplasmic content within autophagosomes followed by their delivery to lysosomes. This process is a survival mechanism, enabling cells to cope with nutrient deprivation by degradation and recycling of macromolecules. Yet during continued stress such as prolonged starvation, a switch from autophagy to apoptosis is often detected. OBJECTIVE: In this work, we characterized the temporal dynamics of the transition from autophagy towards apoptosis with the aim of elucidating the molecular mechanism regulating the switch from survival autophagy to apoptotic cell death...
May 2017: Journal of Internal Medicine
https://www.readbyqxmd.com/read/28419473/translating-the-cognitive-model-of-ptsd-to-the-treatment-of-very-young-children-a-single-case-study-of-an-8-year-old-motor-vehicle-accident-survivor
#8
Benjamin Goodall, Isobel Chadwick, Anna McKinnon, Aliza Werner-Seidler, Richard Meiser-Stedman, Patrick Smith, Tim Dalgleish
Posttraumatic stress disorder (PTSD) is a clinical condition that occurs after a discrete traumatic event, such as an accident or assault. Research into PTSD has primarily been adult-focused; however, there is a growing body of evidence evaluating the theory and treatment of PTSD in young children. Consequently, cognitive behavior therapy (CBT) interventions for PTSD in youth have been developed that focus on 3 core components of the cognitive model-a disorganized memory of the trauma, maladaptive appraisals of the trauma and its effects (meanings), and dysfunctional coping mechanisms (management)...
May 2017: Journal of Clinical Psychology
https://www.readbyqxmd.com/read/28419152/the-disadvantages-of-being-a-hybrid-during-drought-a-combined-analysis-of-plant-morphology-physiology-and-leaf-proteome-in-maize
#9
Dana Holá, Monika Benešová, Lukáš Fischer, Daniel Haisel, František Hnilička, Helena Hniličková, Petr L Jedelský, Marie Kočová, Dagmar Procházková, Olga Rothová, Lenka Tůmová, Naďa Wilhelmová
A comparative analysis of various parameters that characterize plant morphology, growth, water status, photosynthesis, cell damage, and antioxidative and osmoprotective systems together with an iTRAQ analysis of the leaf proteome was performed in two inbred lines of maize (Zea mays L.) differing in drought susceptibility and their reciprocal F1 hybrids. The aim of this study was to dissect the parent-hybrid relationships to better understand the mechanisms of the heterotic effect and its potential association with the stress response...
2017: PloS One
https://www.readbyqxmd.com/read/28418818/-it-is-not-the-diet-it-is-the-mental-part-we-need-help-with-a-multilevel-analysis-of-psychological-emotional-and-social-well-being-in-obesity
#10
Kathryn Rand, Michael Vallis, Megan Aston, Sheri Price, Helena Piccinini-Vallis, Laurene Rehman, Sara F L Kirk
In this research, we explored the psychological, emotional, and social experiences of individuals living with obesity, and perceptions of health care providers. We conducted a theoretical thematic analysis using two theoretical frameworks applied to transcripts from a previous qualitative study. Themes from a mental well-being framework were subsequently categorized under five environmental levels of the Social-Ecological Model (SEM). Key mental well-being themes appeared across all levels of the SEM, except the policy level...
December 2017: International Journal of Qualitative Studies on Health and Well-being
https://www.readbyqxmd.com/read/28415683/suppression-of-pkc-causes-oncogenic-stress-for-triggering-apoptosis-in-cancer-cells
#11
Suthakar Ganapathy, Bo Peng, Ling Shen, Tianqi Yu, Jean Lafontant, Ping Li, Rui Xiong, Alexandros Makriyannis, Changyan Chen
Gain of functional mutations in ras occurs in more than 30% of human malignancies and in particular 90% of pancreatic cancer. Mutant ras, via activating multiple effector pathways, not only promote cell growth or survival, but also apoptosis, depending upon cell types or circumstances. In order to further study the mechanisms of apoptosis induced by oncogenic ras, we employed the ras loop mutant genes and demonstrated that Akt functioned downstream of Ras in human pancreatic cancer or HPNE cells ectopically expressing mutated K-ras for the induction of apoptosis after the concurrent suppression of PKC α and β...
March 9, 2017: Oncotarget
https://www.readbyqxmd.com/read/28414507/the-distinction-between-exclusivity-and-comorbidity-within-nssi
#12
Shira Goldberg, Moshe Israelashvili
Based on notions posited by problem behavior theory, the primary goal of the current study was to examine the possibility that adolescents who engage in NSSI are not a homogeneous group but are rather divided into 2 subgroups: (a) adolescents who exclusively engage in NSSI, and (b) adolescents who are involved in NSSI alongside other problem behaviors (e.g., drug abuse, unprotected sexual intercourse). Participants were a school sample of 436 adolescents from 6 high schools across Israel, who completed self-report questionnaires during school hours on engagement in NSSI and other problem behaviors, self-esteem, self-criticism, ego clarity, coping strategies, self-efficacy to regulate affect, and sociodemographic information...
April 17, 2017: School Psychology Quarterly
https://www.readbyqxmd.com/read/28414264/the-rice-transcription-factors-osice-confer-enhanced-cold-tolerance-in-transgenic-arabidopsis
#13
Cuiyun Deng, Haiyan Ye, Meng Fan, Tongliang Pu, Jianbin Yan
Cold stress is one of the major constraints for crop yield. Plants have in turn evolved highly sophisticated mechanisms involving altered physiological and biochemical processes to cope with the cold stress. Previous studies have revealed that the INDUCER OF CBF EXPRESSION 1 (ICE1), a basic helix-loop-helix (bHLH) transcription factor, directly binds and activates the expression of C-Repeat Binding Factor/Dehydration-Responsive-Element-Binding protein (CBF/DREB1) to regulate the cold-response pathway in Arabidopsis thaliana...
April 17, 2017: Plant Signaling & Behavior
https://www.readbyqxmd.com/read/28414184/mouse-cytomegalovirus-encoded-immunoevasins-and-evolution-of-ly49-receptors-sidekicks-or-enemies
#14
REVIEW
Jelena Zeleznjak, Branka Popovic, Astrid Krmpotic, Stipan Jonjic, Vanda Juranic Lisnic
Cytomegaloviruses (CMVs) have dedicated a large portion of their genome towards immune evasion targeting many aspects of the host immune system, particularly NK cells. However, the host managed to cope with the infection by developing multiple mechanisms to recognize viral threat and counterattack it, thus illustrating never-ending evolutionary interplay between CMV and its host. In this review, we will focus on several mechanisms of NK cell evasion by mouse CMV (MCMV), the role of host inhibitory and activating Ly49 receptors involved in the virus control and acquisition of adaptive features by NK cells as a consequence of MCMV infection...
April 13, 2017: Immunology Letters
https://www.readbyqxmd.com/read/28410266/2-3-5-4-tetrahydroxystilbene-2-o-%C3%AE-d-glucoside-prevention-of-lipopolysaccharide-induced-depressive-like-behaviors-in-mice-involves-neuroinflammation-and-oxido-nitrosative-stress-inhibition
#15
Zhuo Chen, Chao Huang, Haiyan He, Wenbin Ding
Although numerous hypotheses have been raised in recent years, the exact mechanisms that promote the development of major depression are largely unknown. Recently, strategies targeting the process of neuroinflammation and oxidative stress in depression have been attracting greater attention. 2, 3, 5, 4'-Tetrahydroxystilbene-2-O-β-D-glucoside (TSG), a compound purified from a traditional Chinese herbal medicine polygonummultiflorum, has been widely reported to inhibit neuroinflammation and oxidative stress...
April 13, 2017: Behavioural Pharmacology
https://www.readbyqxmd.com/read/28409382/yeast-response-and-tolerance-to-benzoic-acid-involves-the-gcn4-and-stp1-regulated-multidrug-multixenobiotic-resistance-transporter-tpo1
#16
Cláudia P Godinho, Nuno P Mira, Tânia R Cabrito, Miguel C Teixeira, Kaur Alasoo, Joana F Guerreiro, Isabel Sá-Correia
The action of benzoic acid in the food and beverage industries is compromised by the ability of spoilage yeasts to cope with this food preservative. Benzoic acid occurs naturally in many plants and is an intermediate compound in the biosynthesis of many secondary metabolites. The understanding of the mechanisms underlying the response and resistance to benzoic acid stress in the eukaryotic model yeast is thus crucial to design more suitable strategies to deal with this toxic lipophilic weak acid. In this study, the Saccharomyces cerevisiae multidrug transporter Tpo1 was demonstrated to confer resistance to benzoic acid...
April 13, 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28409360/voices-from-flint-community-perceptions-of-the-flint-water-crisis
#17
Nia Jeneé Heard-Garris, Jessica Roche, Patrick Carter, Mahshid Abir, Maureen Walton, Marc Zimmerman, Rebecca Cunningham
We describe the self-reported socioeconomic and health impacts, as well as the coping mechanisms employed by a drug-using cohort of adults during the Flint water crisis (FWC) in Flint, Michigan. Participants from an ongoing longitudinal Emergency Department study were contacted between April 2016 and July 2016 and completed a survey focusing on exposure, consequences, and coping strategies. One hundred thirty-three participants (mean age = 26, 65% African-American, 61% public assistance) completed the survey (37...
April 13, 2017: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/28408661/multiomics-of-tomato-glandular-trichomes-reveals-distinct-features-of-central-carbon-metabolism-supporting-high-productivity-of-specialized-metabolites
#18
Gerd Balcke, Stefan Bennewitz, Nick Bergau, Benedikt Athmer, Anja Henning, Petra Majovsky, José M Jiménez-Gómez, Wolfgang Hoehenwarter, Alain F Tissier
Glandular trichomes are metabolic cell factories with the capacity to produce large quantities of secondary metabolites. Little is known about the connection between central carbon metabolism and metabolic productivity for secondary metabolites in glandular trichomes. To address this gap in our knowledge, we performed comparative metabolomics, transcriptomics, proteomics and 13C-labeling of type VI glandular trichomes and leaves from a cultivated (Solanum lycopersicum LA4024) and a wild (Solanum habrochaites LA1777) tomato accession...
April 13, 2017: Plant Cell
https://www.readbyqxmd.com/read/28403510/-new-to-me-changing-patient-understanding-of-psoriasis-and-identifying-mechanisms-of-change-the-pso-well-%C3%A2-patient-materials-mixed-methods-feasibility-study
#19
P A Nelson, K Kane, C J Pearce, C Bundy, A Chisholm, R Hilton, R Thorneloe, H Young, C E M Griffiths, L Cordingley
BACKGROUND: Psoriasis is an inflammatory, long-term condition (LTC) involving co-morbidities, unhealthy lifestyle and significant life impact. Patients' understanding of psoriasis is limited and support lacking. The Common-Sense Self-Regulatory Model emphasises the role of illness/treatment beliefs on coping/self-management. New 'Pso Well(®) ' patient materials informed by the model addressed: psoriasis as a LTC; medications management; and lifestyle behaviours. OBJECTIVES: To investigate whether Pso Well(®) materials: 1) broaden understanding of psoriasis without increasing anxiety; 2) are acceptable and; 3) comprise features that appear to effect change...
April 12, 2017: British Journal of Dermatology
https://www.readbyqxmd.com/read/28400733/optimization-of-huang-lian-jie-du-decoction-for-ischemic-stroke-treatment-and-mechanistic-study-by-metabolomic-profiling-and-network-analysis
#20
Qian Zhang, Junsong Wang, Shanting Liao, Pei Li, Dingqiao Xu, Yan Lv, Minghua Yang, Lingyi Kong
Optimal drug proportions and mechanism deciphering of multicomponent drugs are critical for developing novel therapies to cope with complex diseases, such as stroke. In the present study, orthogonal experimental design was applied to explore the optimal proportion of the four component herbs in Huang-Lian-Jie-Du-Decoction (HLJDD) on the treatment of ischemic stroke. The treatment efficacies and mechanisms were assessed using global and amino acids (AAs) targeted metabolomics, as well as correlation network analysis...
2017: Frontiers in Pharmacology
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