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Coping Mechanism

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https://www.readbyqxmd.com/read/29776999/stumbling-corrective-reaction-elicited-by-mechanical-and-electrical-stimulation-of-the-saphenous-nerve-in-walking-mice
#1
William Paganini Mayer, Turgay Akay
The ability to walk around in a natural environment requires the capacity to cope with unexpected obstacles that may disrupt locomotion. One such mechanism is called the stumbling corrective reaction (SCR) that enables animals to step over obstacles that would otherwise disturb the progression of swing movement. Here we use in vivo motion analysis and physiological recording techniques to describe the SCR in mice. We show that SCR can be elicited consistently in mice during locomotion by inserting an obstacle along the path of leg movement during swing phase...
May 18, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29775984/static-postural-stability-in-chronic-ankle-instability-an-ankle-sprain-and-healthy-ankles
#2
Yong Ung Kwon
To identify the single leg balance (SLB) test that discriminates among healthy, coper, and chronic ankle instability (CAI) groups and to determine effects of ankle muscles on the balance error scoring system (BESS) among the three populations. 60 subjects (20 per group) performed the SLB test with eyes open (EO) and eyes closed (EC). Normalized mean amplitude (NMA) of the tibia anterior (TA), fibularis longus (FL), and medial gastrocnemius (MG) muscles and BESS were measured while performing the SLB test. The coper group had a lower error score than the CAI group in the EC...
May 18, 2018: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/29774649/end-of-life-trajectory-of-coping-and-self-care-of-patients-with-idiopathic-pulmonary-fibrosis-a-meta-synthesis-using-meta-ethnography
#3
Yasuko Igai
AIM: This study aimed to extract patient narratives regarding the end-of-life trajectory of their self-care and coping experiences as patients with idiopathic pulmonary fibrosis and to use meta-ethnography to discover common metaphors of their experience in order to inform the development of nursing interventions. METHODS: A comprehensive search of qualitative research using electronic databases, in English and Japanese, regarding patients with IPF, identified four articles...
May 17, 2018: Japan Journal of Nursing Science: JJNS
https://www.readbyqxmd.com/read/29774000/does-despotic-leadership-harm-employee-family-life-exploring-the-effects-of-emotional-exhaustion-and-anxiety
#4
Shazia Nauman, Tasneem Fatima, Inam Ul Haq
Research has not focused on the negative effects of despotic leadership on subordinates' life satisfaction and the interface between work and family. Drawing on the Conservation of Resources theory, this research investigates the mediating effect of emotional exhaustion through which despotic leadership transcends from the workplace to subordinates' personal lives, resulting in work-family conflict and decreased life satisfaction. The research also examines the moderating effect of subordinates' anxiety on the relationship of their perceptions of despotic leadership with work-family conflict and life satisfaction...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29772843/the-role-of-trp-channels-in-the-metastatic-cascade
#5
REVIEW
Benedikt Fels, Etmar Bulk, Zoltán Pethő, Albrecht Schwab
A dysregulated cellular Ca2+ homeostasis is involved in multiple pathologies including cancer. Changes in Ca2+ signaling caused by altered fluxes through ion channels and transporters (the transportome) are involved in all steps of the metastatic cascade. Cancer cells thereby "re-program" and "misuse" the cellular transportome to regulate proliferation, apoptosis, metabolism, growth factor signaling, migration and invasion. Cancer cells use their transportome to cope with diverse environmental challenges during the metastatic cascade, like hypoxic, acidic and mechanical cues...
May 17, 2018: Pharmaceuticals
https://www.readbyqxmd.com/read/29771207/the-stopit-programme-to-reduce-bullying-and-undermining-behaviour-in-hospitals
#6
Graham Benmore, Steven Henderson, Joanna Mountfield, Brian Wink
Purpose The impact of bullying and undermining behaviours on the National Health Service on costs, patient safety and retention of staff was well understood even before the Illing report, published in 2013, that reviewed the efficacy of training interventions designed to reduce bullying and harassment in the outputs. The purpose of this paper is to provide an example of a good programme well evaluated. Design/methodology/approach The methodology follows a broad realist approach, by specifying the underlying programme assumptions and intention of the designers...
May 21, 2018: Journal of Health Organization and Management
https://www.readbyqxmd.com/read/29769404/dna-activates-the-nse2-mms21-sumo-e3-ligase-in-the-smc5-6-complex
#7
Nathalia Varejão, Eva Ibars, Jara Lascorz, Neus Colomina, Jordi Torres-Rosell, David Reverter
Modification of chromosomal proteins by conjugation to SUMO is a key step to cope with DNA damage and to maintain the integrity of the genome. The recruitment of SUMO E3 ligases to chromatin may represent one layer of control on protein sumoylation. However, we currently do not understand how cells upregulate the activity of E3 ligases on chromatin. Here we show that the Nse2 SUMO E3 in the Smc5/6 complex, a critical player during recombinational DNA repair, is directly stimulated by binding to DNA Activation of sumoylation requires the electrostatic interaction between DNA and a positively charged patch in the ARM domain of Smc5, which acts as a DNA sensor that subsequently promotes a stimulatory activation of the E3 activity in Nse2...
May 16, 2018: EMBO Journal
https://www.readbyqxmd.com/read/29768430/a-qualitative-study-of-implementation-and-adaptations-to-progressive-tinnitus-management-ptm-delivery
#8
Anaïs Tuepker, Christine Elnitsky, Summer Newell, Tara Zaugg, James A Henry
BACKGROUND: Tinnitus is a common condition, especially prevalent among military Veterans. Progressive Tinnitus Management (PTM) is an interdisciplinary, structured, stepped-care approach to providing clinical services, including teaching coping skills, to people bothered by tinnitus. PTM has been shown to be effective at reducing functional distress, but implementation of the intervention outside of a research setting has not been studied, even though dissemination is underway within the Veterans Health Administration (VHA) system in the United States...
2018: PloS One
https://www.readbyqxmd.com/read/29768205/c-elegans-blastomeres-clear-the-corpse-of-the-second-polar-body-by-lc3-associated-phagocytosis
#9
Gholamreza Fazeli, Maurice Stetter, Jaime N Lisack, Ann M Wehman
To understand how undifferentiated pluripotent cells cope with cell corpses, we examined the clearance of polar bodies born during female meiosis. We found that polar bodies lose membrane integrity and expose phosphatidylserine in Caenorhabditis elegans. Polar body signaling recruits engulfment receptors to the plasma membrane of embryonic blastomeres using the PI3K VPS-34, RAB-5 GTPase and the sorting nexin SNX-6. The second polar body is then phagocytosed using receptor-mediated engulfment pathways dependent on the Rac1 ortholog CED-10 but undergoes non-apoptotic programmed cell death independent of engulfment...
May 15, 2018: Cell Reports
https://www.readbyqxmd.com/read/29763646/genetic-parameter-and-breeding-value-estimation-of-donkeys-problem-focused-coping-styles
#10
Francisco Javier Navas González, Jordi Jordana Vidal, José Manuel León Jurado, Ander Arando Arbulu, Amy Katherine McLean, Juan Vicente Delgado Bermejo
Donkeys are recognized therapy or leisure-riding animals. Anecdotal evidence has suggested that more reactive donkeys or those more easily engaging flight mechanisms tend to be easier to train compared to those displaying the natural donkey behaviour of fight. This context brings together the need to quantify such traits and to genetically select donkeys displaying a neutral reaction during training, because of its implication with handler/rider safety and trainability. We analysed the scores for coping style traits from 300 Andalusian donkeys from 2013 to 2015...
May 12, 2018: Behavioural Processes
https://www.readbyqxmd.com/read/29758498/accumulation-elimination-and-neuro-oxidative-damage-under-lanthanum-exposure-in-glass-eels-anguilla-anguilla
#11
Cátia Figueiredo, Tiago F Grilo, Clara Lopes, Pedro Brito, Mário Diniz, Miguel Caetano, Rui Rosa, Joana Raimundo
Rare earth elements (REEs) comprise elements from lanthanum to lutetium that together with yttrium and scandium are emergent contaminants of critical importance for numerous groundbreaking environmental technologies. Transfer to aquatic ecosystems is expected to increase, however, little information is known about their potential impacts in marine biota. Considering the endangered conservation status of the European eel (Anguilla anguilla) and the vulnerability of early fish life stages to contaminants, we exposed glass eels, through water, to an environmentally relevant concentration (120 ng...
May 7, 2018: Chemosphere
https://www.readbyqxmd.com/read/29758493/spirituality-religiousness-and-coping-in-patients-with-schizophrenia-a-cross-sectional-study-in-a-tertiary-care-hospital
#12
Soumitra Das, Varghese Panickasseril Punnoose, Nimisha Doval, Vijayakrishnan Yathindran Nair
Religion is a form of coping that helps individuals to deal with a wide variety of difficult life situations. But most of the research in this field has been in acute patients of schizophrenia. Also, most of the research on religion and schizophrenia has focused on religion and spirituality as coping mechanisms, and research evaluating the relationship between spirituality/religiousness and repertoire of other coping skills is sparse. Our objective was to evaluate the association between spirituality, religiousness and coping skills in patients with schizophrenia in remission...
April 24, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29758419/seasonal-ionomic-and-metabolic-changes-in-aleppo-pines-growing-on-mine-tailings-under-mediterranean-semi-arid-climate
#13
Antonio López-Orenes, María C Bueso, Héctor Conesa, Antonio A Calderón, María A Ferrer
Aleppo pine is the most abundant conifer species in Mediterranean basin. Knowledge of adaptive mechanisms to cope with different environmental stresses simultaneously is necessary to improve its resilience to the predicted climatic changes and anthropogenic stressors, such as heavy metal/metal(loid)s (HMMs) pollution. Here, one year-old needles and rhizosphere soil samples from five mining and non-mining (NM) populations of Aleppo pines grown spontaneously in SE Spain were sampled in two consecutive years during spring and summer...
May 11, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29758225/trpv6-protects-er-stress-induced-apoptosis-via-atf6%C3%AE-trpv6-jnk-pathway-in-human-embryonic-stem-cell-derived-cardiomyocytes
#14
Zhichao Li, Zhaoyue Meng, Jun Lu, Francis M Chen, Wing-Tak Wong, Gary Tse, Changbo Zheng, Wendy Keung, Kennis Tse, Ronald A Li, Liwen Jiang, Xiaoqiang Yao
Human pluripotent stem cell-derived cardiomyocytes have potential applications in disease modeling and drug screening. Therefore, it is important to understand the mechanisms and signaling pathways underlying the survival and death of these cells. Endoplasmic reticulum (ER) stress is triggered by various cellular stresses that disturb protein folding in the ER. Cells cope with ER stress by activating the unfolded protein response (UPR), a homeostatic signaling network that orchestrates the recovery of ER function...
May 11, 2018: Journal of Molecular and Cellular Cardiology
https://www.readbyqxmd.com/read/29758022/determinants-of-hardship-financing-in-coping-with-out-of-pocket-payment-for-care-seeking-of-under-five-children-in-selected-rural-areas-of-bangladesh
#15
Tazeen Tahsina, Nazia Binte Ali, Md Abu Bakkar Siddique, Sameen Ahmed, Mubashshira Rahman, Sajia Islam, Md Mezanur Rahman, Bushra Amena, D M Emdadul Hoque, Tanvir M Huda, Shams El Arifeen
BACKGROUND: Around 63% of total health care expenditure in Bangladesh is mitigated through out of pocket payment (OOP). Heavy reliance on OOP at the time of care seeking poses great threat for financial impoverishment of the households. Households employ different strategies to cope with the associated financial hardship. OBJECTIVE: The aim of this paper is to understand the determinants of hardship financing in coping with OOP adopted for health care seeking of under five childhood illnesses in rural setting of Bangladesh...
2018: PloS One
https://www.readbyqxmd.com/read/29753694/physiological-adaptation-of-the-growth-restricted-fetus
#16
REVIEW
Karel Maršál
The growth-restricted fetus in utero is exposed to a hostile environment and suffers undernutrition and hypoxia. To cope with the stress, the fetus changes its physiological functions. These adaptive changes aid intrauterine survival; however, they can lead to permanent functional and structural changes that can contribute to the development of serious chronic diseases later in life. Epigenetic mechanisms are an important part of the pathophysiological processes behind this "developmental origin of adult diseases...
February 24, 2018: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29753136/the-allelochemical-trans-cinnamic-acid-stimulates-salicylic-acid-production-and-galactose-pathway-in-maize-leaves-a-potential-mechanism-of-stress-tolerance
#17
Fabrizio Araniti, Antonio Lupini, Antonio Mauceri, Antonino Zumbo, Francesco Sunseri, Maria Rosa Abenavoli
In this study, the effects (5 days) of the secondary metabolite trans-cinnamic acid on maize leaves (Zea mays L.), through a physiological and an untargeted metabolomic approach, were evaluated. A reduction in leaf growth and development accompanied by a decrease in protein content was observed in treated seedlings. Besides, trans-cinnamic acid stimulated the photosynthetic machinery with a significant increment in pigment content (chlorophyll a, b and carotenoids), a stimulation of the light adapted PSII efficiency (ɸII ) as well as the chlorophyll a fluorescence (YNO ), the apparent electron transport rate, and the regulated dissipation of the energy (YNPQ )...
May 5, 2018: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/29748546/nutrient-depletion-induced-production-of-tri-acylated-glycerophospholipids-in-acinetobacter-radioresistens
#18
Yu Luo, Muhammad Afzal Javed, Harry Deneer, Xialu Chen
Bacteria inhabit a vast range of biological niches and have evolved diverse mechanisms to cope with environmental stressors. The genus Acinetobacter comprises a complex group of Gram-negative bacteria. Some of these bacteria such as A. baumannii are nosocomial pathogens. They are often resistant to multiple antibiotics and are associated with epidemic outbreaks. A. radioresistens is generally considered to be a commensal bacterium on human skin or an opportunistic pathogen. Interestingly, this species has exceptional resistance to a range of environmental challenges which contributes to its persistence in clinical environment and on human skin...
May 10, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29746664/translational-control-plays-an-important-role-in-the-adaptive-heat-shock-response-of-streptomyces-coelicolor
#19
Giselda Bucca, Radhika Pothi, Andrew Hesketh, Carla Möller-Levet, David A Hodgson, Emma E Laing, Graham R Stewart, Colin P Smith
Stress-induced adaptations require multiple levels of regulation in all organisms to repair cellular damage. In the present study we evaluated the genome-wide transcriptional and translational changes following heat stress exposure in the soil-dwelling model actinomycete bacterium, Streptomyces coelicolor. The combined analysis revealed an unprecedented level of translational control of gene expression, deduced through polysome profiling, in addition to transcriptional changes. Our data show little correlation between the transcriptome and 'translatome'; while an obvious downward trend in genome wide transcription was observed, polysome associated transcripts following heat-shock showed an opposite upward trend...
May 9, 2018: Nucleic Acids Research
https://www.readbyqxmd.com/read/29746216/digital-ethnography-of-zoophilia-a-multinational-mixed-methods-study
#20
Damian Jacob Sendler, Michal Lew-Starowicz
INTRODUCTION: This study investigates people who have sex with animals (PSA) by describing their living situation, sexual activity, beliefs, and attitudes toward stigmatization. These data are highly applicable to the work of psychiatric and forensic professionals investigating paraphilias. METHODS: We apply mixed-methods approach, using qualitative and quantitative analyses. RESULTS: The findings come from anonymous forum postings of 953 participants; of which 345 agreed to complete a survey upon advertising the study...
May 10, 2018: Journal of Sex & Marital Therapy
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