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Neuromuscular control

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https://www.readbyqxmd.com/read/29793126/effect-of-manual-therapy-versus-proprioceptive-neuromuscular-facilitation-in-dynamic-balance-mobility-and-flexibility-in-field-hockey-players-a-randomized-controlled-trial
#1
Gemma V Espí-López, Susana López-Martínez, Marta Inglés, Pilar Serra-Añó, Marta Aguilar-Rodríguez
OBJECTIVES: To compare the effectiveness of a specific Manual Therapy (MT) protocol applied to field hockey players (FHP), versus a Proprioceptive Neuromuscular Facilitation (PNF) protocol, in the improvement of dynamic balance, active range of movement and lumbar flexibility one-week and four-weeks after the treatment. DESIGN: Randomized controlled trial. Participants were assigned to 2 groups: MT and PNF. 30 min' sessions were performed once a week for three weeks...
April 22, 2018: Physical Therapy in Sport
https://www.readbyqxmd.com/read/29792554/effect-of-acetazolamide-and-methazolamide-on-diaphragm-and-dorsiflexor-fatigue-a-randomized-controlled-trial
#2
Paolo B Dominelli, Chris J McNeil, Tyler Dennis Vermeulen, Troy J R Stuckless, Courtney V Brown, Giulio S Dominelli, Erik Richard Swenson, Lucas J Teppema, Glen Edward Foster
Acetazolamide, a carbonic anhydrase (CA) inhibitor used clinically and to prevent acute mountain sickness, worsens skeletal muscle fatigue in animals and humans. In animals, methazolamide, a methylated analogue of acetazolamide and an equally potent CA inhibitor, reportedly exacerbates fatigue less than acetazolamide. Accordingly, we sought to determine, in humans, if methazolamide would attenuate diaphragm and dorsiflexor fatigue compared to acetazolamide. Healthy men (dorsiflexor: n=12; diaphragm: n=7) performed fatiguing exercise on three occasions, after ingesting acetazolamide (250 mg three times a day) and then in random order, methazolamide (100 mg twice a day) or placebo for 48 h...
May 24, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29791704/use-of-neuromuscular-electrical-stimulation-during-physical-therapy-may-reduce-the-incidence-of-arthrofibrosis-after-total-knee-arthroplasty
#3
Chukwuweike U Gwam, Tanner McGinnis, Jennifer I Etcheson, Nicole E George, Assem A Sultan, Ronald E Delanois, Anil Bhave, Steven F Harwin, Michael A Mont
INTRODUCTION: Arthrofibrosis remains a major complication following total knee arthroplasty (TKA) that negatively impacts patient outcomes and exhausts healthcare resources. The use of neuromuscular electrical stimulation (NMES) has demonstrated the ability to facilitate quadriceps muscle recovery and reduce pain. Therefore, the purpose of this study was to compare TKA patients who received physical therapy (PT) and adjuvant NMES therapy versus physical therapy alone in terms of: 1) rates of manipulation under anesthesia (MUA) to treat arthrofibrosis; and 2) post-therapy range of motion (ROM)...
June 1, 2018: Surgical Technology International
https://www.readbyqxmd.com/read/29790207/the-repeated-bout-effect-can-occur-without-mechanical-and-neuromuscular-changes-after-a-bout-of-eccentric-exercise
#4
Patricio A Pincheira, Ben W Hoffman, Andrew G Cresswell, Timothy J Carroll, Nicholas A T Brown, Glen A Lichtwark
Changes in muscle fascicle mechanics have been postulated to underpin the repeated bout effect (RBE) observed following exercise-induced muscle damage (EIMD). However, in the medial gastrocnemius (MG), mixed evidence exists on whether fascicle stretch amplitude influences the level of EIMD, thus questioning whether changes in fascicle mechanics underpin the RBE. An alternative hypothesis is that neural adaptations contribute to the RBE in this muscle. The aim of this study was to investigate neuromechanical adaptations during and after repeated bouts of a highly controlled muscle lengthening exercise that aimed to maximise EIMD in MG...
May 23, 2018: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29788511/training-effects-of-alternated-and-pulsed-currents-on-the-quadriceps-muscles-of-athletes
#5
Pedro Oliveira, Karenina Arrais Guida Modesto, Martim Bottaro, Nicolas Babault, João Luiz Quagliotti Durigan
The aim of the study was to evaluate the effects of 6 weeks training with different neuromuscular electrical stimulation (NMES) currents (medium alternated and low-frequency pulsed current) on muscle architecture and neuromuscular performance of competitive athletes. A double-blind controlled and randomized experimental study was carried out with 33 athletes (22.2±2.6 yrs, 74.7±9.8 kg, 176.8±6.0 cm), divided into 3 groups: mid-frequency current (MF, n=12), pulsed current (PC, n=11) and the control group (CG, n=10)...
May 22, 2018: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/29787475/isometric-versus-dynamic-measurements-of-fatigue-does-age-matter-a-meta-analysis
#6
Renata L Krüger, Saied Jalal Aboodarda, Pierre Samozino, Charles L Rice, Guillaume Y Millet
PURPOSE: The assessment of power changes after fatiguing exercise provides important additional information about neuromuscular function compared to traditional isometric measurements, especially when exploring age-related changes in fatigability. Therefore, the aim of this review was to explore the effects of age on neuromuscular fatigue (NMF) when measured in isometric compared with dynamic contractions. The importance of central and peripheral mechanisms contributing to age-related NMF were discussed...
May 22, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29779590/pathophysiology-of-neuromuscular-respiratory-diseases
#7
REVIEW
Joshua O Benditt
Gas exchange between the atmosphere and the human body depends on the lungs and the function of the respiratory pump. The respiratory pump consists of the respiratory control center located in the brain, bony rib cage, diaphragm, and intercostal, accessory, and abdominal muscles. A variety of muscles serve to fine-tune adjustments of ventilation to metabolic demands. Appropriate evaluation and interventions can prevent respiratory complications and prolong life in individuals with neuromuscular diseases. This article discusses normal function of the respiratory pump, general pathophysiologic issues, and abnormalities in more common neuromuscular diseases...
June 2018: Clinics in Chest Medicine
https://www.readbyqxmd.com/read/29779423/cognitive-performance-and-locomotor-adaptation-in-persons-with-anterior-cruciate-ligament-reconstruction
#8
Amanda E Stone, Jaimie A Roper, Daniel C Herman, Chris J Hass
BACKGROUND: Persons with anterior cruciate ligament reconstruction (ACLR) show deficits in gait and neuromuscular control following rehabilitation. This altered behavior extends to locomotor adaptation and learning, however the contributing factors to this observed behavior have yet to be investigated. OBJECTIVE: The purpose of this study was to assess differences in locomotor adaptation and learning between ACLR and controls, and identify underlying contributors to motor adaptation in these individuals...
May 1, 2018: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29779178/organophosphate-pesticides-alter-blue-crab-callinectes-sapidus-behavior-in-single-and-consecutive-exposures
#9
Kelly M Correia, Delbert L Smee
Insecticide effects on nontarget organisms most commonly involve measuring mortality after single exposures. We examined sublethal effects of consecutive exposures of malathion, an organophosphate insecticide used for mosquito abatement, on the behavior of blue crabs (Callinectes sapidus). We measured righting time (i.e., time to return upright when placed upside down), eyestalk reflexes, foraging ability, and response to predation risk in three malathion treatments of 50 µg/L that varied in duration: (1) static exposure for 96 h followed by a second exposure for 96 h, (2) static exposure for 96 h followed by transfer to pesticide-free water for 96 h, (3) control without malathion for 192 h...
May 19, 2018: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/29777980/trunk-postural-adjustments-medium-term-reliability-and-correlation-with-changes-of-clinical-outcomes-following-an-8-week-lumbar-stabilization-exercise-program
#10
Jean-Alexandre Boucher, Richard Preuss, Sharon M Henry, Marilee Nugent, Christian Larivière
BACKGROUND: Low back pain (LBP) has been previously associated with delayed anticipatory postural adjustments (APAs) determined by trunk muscle activation. Lumbar stabilization exercise programs (LSEP) for patients with LBP may restore the trunk neuromuscular control of the lumbar spine, and normalize APAs. This exploratory study aimed at testing the reliability of EMG and kinematics-based postural adjustment measures over an 8-week interval, assessing their sensitivity to LBP status and treatment and examining their relationship with clinical outcomes...
April 22, 2018: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/29777714/efficiency-of-neuromuscular-electrical-stimulation-and-transcutaneous-nerve-stimulation-on-hemiplegic-shoulder-pain-a-prospective-randomized-controlled-trial
#11
Meimei Zhou, Fang Li, Weibo Lu, Junfa Wu, Song Pei
OBJECTIVE: To compare the efficacy of neuromuscular electrical stimulation (NMES) and transcutaneous nerve stimulation (TENS) on hemiplegic shoulder pain (HSP). DESIGN: This is a prospective randomized controlled trial (RCT). SETTING: A total of 184 HSP patients, aged 18-80 years, were recruited in the Rehabilitation Hospital from February 2014 to July 2016. The Ethics approval was obtained from the Institutional Review Board of the Hospital...
May 16, 2018: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/29777332/influence-of-tetanic-stimulation-on-the-staircase-phenomenon-and-the-acceleromyographic-time-course-of-neuromuscular-block-a-randomized-controlled-trial
#12
Guido Mazzinari, Carlos L Errando, Oscar Díaz-Cambronero, Manuel Martin-Flores
During neuromuscular monitoring, repeated electrical stimulation evokes muscle responses of increasing magnitude ('staircase phenomenon', SP). We aimed to evaluate whether SP affects time course and twitches' values of an acceleromyographic assessed neuromuscular block with or without previous tetanic stimulation. Fifty adult patients were randomized to receive a 50 Hz tetanic stimulus (S group) or not (C group) before monitor calibration. After 20 min of TOF ratio (TOFr) stimulation rocuronium was administered...
May 18, 2018: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/29775909/sensorimotor-control-and-neuromuscular-activity-of-the-shoulder-in-adolescent-competitive-swimmers-with-generalized-joint-hypermobility
#13
Thomas Frydendal, Henrik Eshøj, Behnam Liaghat, Pascal Edouard, Karen Søgaard, Birgit Juul-Kristensen
INTRODUCTION: Shoulder pain is highly prevalent in competitive swimmers, and generalized joint hypermobility (GJH) is considered a risk factor. Sensorimotor control deficiencies and altered neuromuscular activation of the shoulder may represent underlying factors. RESEARCH QUESTION: To investigate whether competitive swimmers with GJH including shoulder hypermobility (GJHS) differ in shoulder sensorimotor control and muscle activity from those without GJH and no shoulder hypermobility (NGJH)...
May 5, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29770120/multiparametric-analysis-of-sniff-nasal-inspiratory-pressure-test-in-middle-stage-amyotrophic-lateral-sclerosis
#14
Antonio Sarmento, Andrea Aliverti, Layana Marques, Francesca Pennati, Mario Emílio Dourado-Júnior, Guilherme Fregonezi, Vanessa Resqueti
The relaxation rates and contractile properties of inspiratory muscles are altered with inspiratory muscle weakness and fatigue. This fact plays an important role in neuromuscular disorders patients and had never been extensively studied in amyotrophic lateral sclerosis (ALS). In this cross-sectional study, these parameters were investigated non-invasively through nasal inspiratory sniff pressure test (SNIP) in 39 middle stage spinal onset ALS subjects and compared with 39 healthy controls. ALS patients were also divided into three subgroups according to a decline in their percentage of predicted forced vital capacity (FVC%pred ) as well as a decline in the ALS functional rating scale score and its respiratory subscore (R-subscore) in order to determine the best parameter linked to early respiratory muscle weakness...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29769834/continuous-knee-cooling-affects-functional-hop-performance-a-randomized-controlled-trial
#15
Bruno Tassignon, Ben Serrien, Kevin De Pauw, Jean-Pierre Baeyens, Romain Meeusen
Cryotherapy is widely used in sports and rehabilitation to aid recovery and injury management. The purpose was to examine if a low temperature computer controlled continuous knee cooling protocol (10°C) for one hour and a moderate continuous knee cooling protocol (18°C) for one hour affected neuromuscular activity and functional performance tests. We used a randomized controlled study design. Twenty healthy male subjects (age = 24 ± 3 years) were included and randomized into 2 groups (10°C and 18°C). On day one, participants performed a maximal voluntary contraction of the quadriceps (MVC), single leg hop for distance (SLHD), and crossover hop for time (COHT) with both legs before and after cooling of their right leg...
June 2018: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/29768404/tissue-specific-activities-of-the-fat1-cadherin-cooperate-to-control-neuromuscular-morphogenesis
#16
Françoise Helmbacher
Muscle morphogenesis is tightly coupled with that of motor neurons (MNs). Both MNs and muscle progenitors simultaneously explore the surrounding tissues while exchanging reciprocal signals to tune their behaviors. We previously identified the Fat1 cadherin as a regulator of muscle morphogenesis and showed that it is required in the myogenic lineage to control the polarity of progenitor migration. To expand our knowledge on how Fat1 exerts its tissue-morphogenesis regulator activity, we dissected its functions by tissue-specific genetic ablation...
May 16, 2018: PLoS Biology
https://www.readbyqxmd.com/read/29766505/esophageal-multimodal-stimulation-and-sensation
#17
REVIEW
Dag Arne Lihaug Hoff, Barry McMahon, Hans Gregersen
Esophageal mechanosensation describes the relationship between a mechanical stimulation of the esophageal wall, such as bag distension, and the reaction to the stimulation perceived or unperceived. When studying mechanosensation in esophageal disease, it is important to recognize that symptoms might be due to alterations at different levels of the neuromuscular system, such as alterations at the mechanoreceptor level or in the afferent mechanosensory pathways, or irregularities in the homeostatic state. One might ask if it is possible to provoke, record, and describe the multidimensional responses behind a mechanosensory experience? It is a complex system and, at a minimum, a multidisciplinary approach is needed to avoid erroneous conclusions...
May 16, 2018: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29764981/mice-with-endogenous-tdp-43-mutations-exhibit-gain-of-splicing-function-and-characteristics-of-amyotrophic-lateral-sclerosis
#18
Pietro Fratta, Prasanth Sivakumar, Jack Humphrey, Kitty Lo, Thomas Ricketts, Hugo Oliveira, Jose M Brito-Armas, Bernadett Kalmar, Agnieszka Ule, Yichao Yu, Nicol Birsa, Cristian Bodo, Toby Collins, Alexander E Conicella, Alan Mejia Maza, Alessandro Marrero-Gagliardi, Michelle Stewart, Joffrey Mianne, Silvia Corrochano, Warren Emmett, Gemma Codner, Michael Groves, Ryutaro Fukumura, Yoichi Gondo, Mark Lythgoe, Erwin Pauws, Emma Peskett, Philip Stanier, Lydia Teboul, Martina Hallegger, Andrea Calvo, Adriano Chiò, Adrian M Isaacs, Nicolas L Fawzi, Eric Wang, David E Housman, Francisco Baralle, Linda Greensmith, Emanuele Buratti, Vincent Plagnol, Elizabeth Mc Fisher, Abraham Acevedo-Arozena
TDP-43 (encoded by the gene TARDBP ) is an RNA binding protein central to the pathogenesis of amyotrophic lateral sclerosis (ALS). However, how TARDBP mutations trigger pathogenesis remains unknown. Here, we use novel mouse mutants carrying point mutations in endogenous Tardbp to dissect TDP-43 function at physiological levels both in vitro and in vivo Interestingly, we find that mutations within the C-terminal domain of TDP-43 lead to a gain of splicing function. Using two different strains, we are able to separate TDP-43 loss- and gain-of-function effects...
May 15, 2018: EMBO Journal
https://www.readbyqxmd.com/read/29763710/diabetes-mellitus-in-friedreich-ataxia-a-case-series-of-19-patients-from-the-german-austrian-diabetes-mellitus-registry
#19
Angeliki Pappa, Martin G Häusler, Andreas Veigel, Konstantina Tzamouranis, Martin W Pfeifer, Andreas Schmidt, Martin Bökamp, Holger Haberland, Siegfried Wagner, Joachim Brückel, Gideon de Sousa, Lukas Hackl, Esther Bollow, Reinhard W Holl
Friedreich ataxia (FRDA) is a multisystem autosomal recessive disease with progressive clinical course involving the neuromuscular and endocrine system. Diabetes mellitus (DM) is one typical non-neurological manifestation, caused by beta cell failure and insulin resistance. Because of its rarity, knowledge on DM in FRDA is limited. Based on data from 200 301 patients with DM of the German-Austrian diabetes registry (DPV) and two exemplary patient reports, characteristics of patients with DM and FRDA are compared with classical type 1 or type 2 diabetes...
May 12, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29761274/lower-intra-abdominal-pressure-has-no-cardiopulmonary-benefits-during-laparoscopic-colorectal-surgery-a-double-blind-randomized-controlled-trial
#20
Youn Joung Cho, Hyesun Paik, Seung-Yong Jeong, Ji Won Park, Woo Young Jo, Yunseok Jeon, Kook Hyun Lee, Jeong-Hwa Seo
BACKGROUND: Higher intra-abdominal pressure may impair cardiopulmonary functions during laparoscopic surgery. While 12-15 mmHg is generally recommended as a standard pressure, the benefits of lower intra-abdominal pressure are unclear. We thus studied whether the low intra-abdominal pressure compared with the standard pressure improves cardiopulmonary dynamics during laparoscopic surgery. METHODS: Patients were randomized according to the intra-abdominal pressure and neuromuscular blocking levels during laparoscopic colorectal surgery: low pressure (8 mmHg) with deep-block (post-tetanic count 1-2), standard pressure (12 mmHg) with deep-block, and standard pressure with moderate-block (train-of-four count 1-2) groups...
May 14, 2018: Surgical Endoscopy
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