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Treatment postpartum depression

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https://www.readbyqxmd.com/read/29790850/-the-practical-considerations-of-antidepressant-use-during-pregnancy-and-breastfeeding
#1
Peter Dome, Gabor Faludi
Main indications of antidepressants (ADs) as major depressive disorder (MDD) and different kinds of anxiety disorders are quite prevalent during pregnancy and the postpartum period. Due to the possible hazards of in utero and breast milk exposition of ADs, both psychiatrists and mothers frequently have concerns about the use of ADs during the periods of pregnancy and breastfeeding. However, we should also bear in mind that affective disorders left untreated during these periods are also associated with health risks for the mother and the baby as well...
March 2018: Neuropsychopharmacologia Hungarica
https://www.readbyqxmd.com/read/29767687/hormone-responsive-genes-in-the-shh-and-wnt-%C3%AE-catenin-signaling-pathways-influence-urethral-closure-and-phallus-growth
#2
Yu Chen, Hongshi Yu, Andrew J Pask, Asao Fujiyama, Yutaka Suzuki, Sumio Sugano, Geoff Shaw, Marilyn B Renfree
Environmental endocrine disruptors (EEDs) that affect androgen or estrogen activity may disrupt gene regulation during normal phallus development to cause hypospadias or a masculinized clitoris. We treated developing male tammar wallabies with estrogen and females with androgen from day 20-40 postpartum (pp) during the established androgen imprinting window. Administration of estrogen to males inhibited phallus elongation but had no effect on urethral closure and did not significantly depress testicular androgen synthesis...
May 14, 2018: Biology of Reproduction
https://www.readbyqxmd.com/read/29758402/lactation-related-changes-in-tissue-expression-of-pedf-in-dairy-cows
#3
H Sadri, B Saremi, S Dänicke, J Rehage, M Mielenz, A Hosseini, H Sauerwein
Pigment epithelium-derived factor (PEDF) is evolving as metabolic regulatory protein. Albeit mostly considered in only pathological conditions related to excess energy intake resulting in obesity and insulin resistance, PEDF is likely to be involved in other physiological processes such as the homeorhetic adaptation of metabolism to lactation. We aimed to characterize the expression of PEDF and its association to the concomitant mobilization of body reserves during lactation in nonobese subjects. This mobilization is particularly distinct in dairy cows, and we therefore assessed the mRNA expression of PEDF and its putative receptors in different tissues in 2 trials with dairy cows fed with or without conjugated linoleic acids (CLAs)...
April 17, 2018: Domestic Animal Endocrinology
https://www.readbyqxmd.com/read/29757074/differences-in-screening-and-treatment-for-antepartum-versus-postpartum-patients-are-providers-implementing-the-guidelines-of-care-for-perinatal-depression
#4
Gina L Fedock, Carmen Alvarez
BACKGROUND: National guidelines recommend universal depression screening for perinatal patients and provide treatment recommendations to prevent adverse maternal/child health outcomes. However, providers rarely screen all patients, and most women with perinatal depression remain undertreated. This study investigated predictors of universal screening and guideline-congruent care for perinatal depression by obstetrician-gynecologists and examined differences in practices with pregnant and postpartum patients...
May 14, 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29752621/correlates-of-suicidal-ideation-during-pregnancy-and-postpartum-among-women-living-with-hiv-in-rural-south-africa
#5
Violeta J Rodriguez, Lissa N Mandell, Suat Babayigit, Rhea R Manohar, Stephen M Weiss, Deborah L Jones
In developing countries, up to 20% of maternal deaths during pregnancy are due to suicide, and being HIV-infected confers additional risk. This manuscript sought to identify perinatal correlates of suicidal ideation among women living with HIV (WLHIV) in rural South Africa. Pregnant WLHIV (N = 681) were recruited and re-assessed at 12-months postpartum. Mean age was 28.3 (SD = 5.7) years and 68% were below the poverty line. Prenatal suicidal ideation was 39%; suicidal ideation continued for 7% at 12 months, 13% experienced incident suicidal ideation, and for 19% suicidal ideation had stopped postnatally...
May 11, 2018: AIDS and Behavior
https://www.readbyqxmd.com/read/29716471/-treatment-satisfaction-of-mothers-with-postpartum-depression-concerning-circle-of-security-intervention
#6
Sarah Luisa Moschner, Sandra Achtergarde, Brigitte Ramsauer
Treatment Satisfaction of Mothers with Postpartum Depression Concerning Circle of Security Intervention Treatment satisfaction of mothers with postpartum depression who undergo mother-infant treatment is rarely examined, albeit seen as one aspect of treatment success. This study deals with maternal treatment satisfaction concerning the Circle of Security (COS) group intervention, compared to standard-mother-infant treatment (TAU), within a RCT trial. Treatment satisfaction was captured by the Fragebogen zur Beurteilung der Behandlung (FBB-E) of 52 mothers assigned to COS or TAU at children's age between 16 to 18 months...
May 2018: Praxis der Kinderpsychologie und Kinderpsychiatrie
https://www.readbyqxmd.com/read/29709411/-we-don-t-want-to-be-judged-perceptions-about-professional-help-and-attitudes-towards-help-seeking-among-pregnant-and-postpartum-mexican-american-adolescents
#7
Pamela Recto, Jane Dimmitt Champion
PURPOSE: The purpose of this qualitative study is to understand how depression is recognized, as well as perceptions of professional help and attitudes concerning perinatal depression among pregnant and postpartum (perinatal) Mexican-American adolescents. DESIGN AND METHODS: This qualitative descriptive study used deductive and inductive content analysis to analyze data. Categories and subcategories describing the mental health literacy of perinatal Mexican-American adolescents concerning perinatal depression are presented...
April 27, 2018: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/29695824/postpartum-psychiatric-disorders
#8
REVIEW
Samantha Meltzer-Brody, Louise M Howard, Veerle Bergink, Simone Vigod, Ian Jones, Trine Munk-Olsen, Simone Honikman, Jeannette Milgrom
Pregnancy is a complex and vulnerable period that presents a number of challenges to women, including the development of postpartum psychiatric disorders (PPDs). These disorders can include postpartum depression and anxiety, which are relatively common, and the rare but more severe postpartum psychosis. In addition, other PPDs can include obsessive-compulsive disorder, post-traumatic stress disorder and eating disorders. The aetiology of PPDs is a complex interaction of psychological, social and biological factors, in addition to genetic and environmental factors...
April 26, 2018: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/29684795/screening-for-postpartum-anxiety-a-quality-improvement-project-to-promote-the-screening-of-women-suffering-in-silence
#9
Sarah Toler, Susan Stapleton, Kim Kertsburg, Tiffany J Callahan, Marie Hastings-Tolsma
BACKGROUND: Postpartum anxiety is a mental health problem that has largely been ignored by maternity care providers despite an estimated incidence as high as 28.9%. Though postpartum anxiety may or may not be accompanied by depression, and while screening for postpartum depression has become more common place, postpartum anxiety is often not assessed or addressed. PURPOSE: The purpose of this pilot quality improvement project was to implement a screening, treatment and referral program for postpartum anxiety in the birth centre environment...
April 3, 2018: Midwifery
https://www.readbyqxmd.com/read/29683308/maternity-care-update-postpartum-care
#10
Andrew Smith, Wendy B Barr, Erin Bassett-Novoa, Nicholas LeFevre
Family physicians are uniquely situated to play a major role in postpartum care. Postpartum issues that should be monitored and addressed include reproductive and contraceptive planning, breastfeeding counseling and support, and maternal mental health. All women should be screened for postpartum depression using a validated tool at the postpartum visit and/or at well-child visits. Patients with positive screening results should be offered support and treatment. Women are more likely to breastfeed if they are provided with breastfeeding support and counseling routinely during the prenatal and postpartum periods...
April 2018: FP Essentials
https://www.readbyqxmd.com/read/29675280/what-can-happen-when-postpartum-anxiety-progresses-to-psychosis-a-case-study
#11
Vesna Pirec
This case report describes a primipara without documented psychiatric history prior to complicated delivery. Onset of severe insomnia and anxiety was right after childbirth but not treated. Obsessive thinking pattern became more prominent. The patient became depressed and sought psychiatric help four months after delivery. Insomnia was then treated pharmacologically. Anxiety and depression persisted, suicidal ideation emerged, and the patient became confused, indecisive, overwhelmed, and delusional regarding her child's health...
2018: Case Reports in Psychiatry
https://www.readbyqxmd.com/read/29669175/antidepressants-for-preventing-postnatal-depression
#12
REVIEW
Emma Molyneaux, Laurence A Telesia, Carol Henshaw, Elizabeth Boath, Eleanor Bradley, Louise M Howard
BACKGROUND: Depression is common in the postnatal period and can lead to adverse effects on the infant and wider family, in addition to the morbidity for the mother. It is not clear whether antidepressants are effective for the prevention of postnatal depression and little is known about possible adverse effects for the mother and infant, particularly during breastfeeding. This is an update of a Cochrane Review last published in 2005. OBJECTIVES: To assess the effectiveness of antidepressant medication for the prevention of postnatal depression, in comparison with any other treatment, placebo or standard care...
April 18, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29660641/improvement-of-postpartum-depression-and-psychosis-after-electroconvulsive-therapy-a-population-based-study-with-a-matched-comparison-group
#13
Sara Rundgren, Ole Brus, Ullvi Båve, Mikael Landén, Johan Lundberg, Pia Nordanskog, Axel Nordenskjöld
INTRODUCTION: Electroconvulsive therapy (ECT) is used to treat postpartum depression and psychosis based on clinical experience and small observational studies. AIMS: The primary aim was to test the hypothesis that the response rate to ECT for depression and psychosis is higher during the postpartum period than outside this period. The secondary aim was to identify predictors of a response to ECT during the postpartum period. MATERIALS AND METHODS: Cases with postpartum depression and/or psychosis received ECT within 6 months of delivery...
April 9, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29659372/consequences-of-antepartum-depression
#14
Jonathan Schaffir
To counsel women about risks and benefits of depression treatment during pregnancy, clinicians must appreciate the potential consequences of untreated depression on the mother and her unborn child. Many studies have demonstrated associations between untreated depression during pregnancy and a range of adverse outcomes, including low birth weight, preterm delivery, preeclampsia, emergent operative delivery, postpartum depression, and both cognitive and behavioral deficits in the child. Although most of these associations are marked by low odds ratios and a host of potential confounding issues, they collectively provide considerable rationale for identifying depression in pregnancy and offering treatment for mothers at risk...
April 13, 2018: Clinical Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29653295/feasibility-of-a-mindfulness-based-cognitive-therapy-group-intervention-as-an-adjunctive-treatment-for-postpartum-depression-and-anxiety
#15
Barbara Shulman, Royce Dueck, Deirdre Ryan, Genevieve Breau, Isabel Sadowski, Shaila Misri
BACKGROUND: Many women experience moderate-to-severe depression and anxiety in the postpartum period for which pharmacotherapy is often the first-line treatment. Many breastfeeding mothers are reticent to increase their dose or consider additional medication, despite incomplete response, due to potential adverse effects on their newborn. These mothers are amenable to non-pharmacological intervention for complete symptom remission. The current study evaluated the feasibility of an eight-week mindfulness-based cognitive therapy (MBCT) intervention as an adjunctive treatment for postpartum depression and anxiety...
January 2, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29652937/trajectories-of-maternal-depressive-symptoms-during-pregnancy-and-the-first-12-months-postpartum-and-child-externalizing-and-internalizing-behavior-at-three-years
#16
Dawn Kingston, Heather Kehler, Marie-Paule Austin, Muhammad Kashif Mughal, Abdul Wajid, Lydia Vermeyden, Karen Benzies, Stephanie Brown, Scott Stuart, Rebecca Giallo
BACKGROUND: Most evidence of the association between maternal depression and children's development is limited by being cross-sectional. To date, few studies have modelled trajectories of maternal depressive symptoms from pregnancy through the early postpartum years and examined their association with social emotional and behavior functioning in preschool children. The objectives of this study were to: 1) identify distinct groups of women defined by their trajectories of depressive symptoms across four time points from mid-pregnancy to one year postpartum; and 2) examine the associations between these trajectories and child internalizing and externalizing behaviors...
2018: PloS One
https://www.readbyqxmd.com/read/29619936/intravenous-iron-treatment-in-the-puerperium
#17
Charlotte Holm
Iron deficiency and anaemia in the puerperium are associated with several important clinical consequences, most prominently physical fatigue. Current treatment practice with oral iron supplementation is associated with gastrointestinal side-effects and subsequent poor compliance. Red blood cell transfusion is also widely used to treat severe postpartum anaemia, though accumulating evidence questions its risk-benefit ratio. Intravenous iron has in previous studies been associated with fast improvement of haemoglobin and iron biochemical markers in the treatment of postpartum anaemia, but there is a lack of studies on patient reported outcomes...
April 2018: Danish Medical Journal
https://www.readbyqxmd.com/read/29616334/effectiveness-of-self-help-psychological-interventions-for-treating-and-preventing-postpartum-depression-a-meta-analysis
#18
REVIEW
Ping-Zhen Lin, Jiao-Mei Xue, Bei Yang, Meng Li, Feng-Lin Cao
Previous studies have reported different effect sizes for self-help interventions designed to reduce postpartum depression symptoms; therefore, a comprehensive quantitative review of the research was required. A meta-analysis was conducted to examine the effectiveness of self-help interventions designed to treat and prevent postpartum depression, and identified nine relevant randomized controlled trials. Differences in depressive symptoms between self-help interventions and control conditions, changes in depressive symptoms following self-help interventions, and differences in postintervention recovery and improvement rates between self-help interventions and control conditions were assessed in separate analyses...
April 4, 2018: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/29603017/an-open-label-pilot-study-of-a-home-wearable-light-therapy-device-for-postpartum-depression
#19
Leslie M Swanson, Helen J Burgess, Jennifer Zollars, J Todd Arnedt
We sought to establish the feasibility and preliminary effects of home-wearable light therapy for postpartum depression, and its effects on circadian measures. Eight women within 6 months postpartum were prescribed 60 min of daily morning light therapy for 5 weeks. The device was well tolerated. Significant improvements were observed in self-report and clinician-rated depression symptoms, with little change in objective circadian measures. Home-wearable light therapy is feasible for postpartum women and may be a promising treatment for postpartum depression...
March 30, 2018: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/29579632/maternal-exercise-increases-but-concurrent-maternal-fluoxetine-prevents-the-increase-in-hippocampal-neurogenesis-of-adult-offspring
#20
Aarthi R Gobinath, Sarah Wong, Carmen Chow, Stephanie E Lieblich, Alasdair M Barr, Liisa A M Galea
Treating postpartum depression (PPD) with pharmacological antidepressants like fluoxetine (FLX) is complicated because these drugs can remain active in breast milk and potentially affect infant development. Alternatively, non-pharmacological treatments such as exercise are associated with beneficial effects on infant development but its potential ability to counter the effects of PPD are largely unknown. To investigate this, we treated dams with corticosterone (CORT) or vehicle (sesame oil) from postpartum days 2-25 to model PPD...
May 2018: Psychoneuroendocrinology
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