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clinical biomechanics

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https://www.readbyqxmd.com/read/28339828/single-session-of-functional-electrical-stimulation-assisted-walking-produces-corticomotor-symmetry-changes-related-to-changes-in-poststroke-walking-mechanics
#1
Jacqueline A Palmer, HaoYuan Hsiao, Tamara Wright, Stuart A Binder-Macleod
Background: Recent research demonstrated that symmetry of corticomotor drive to paretic and nonparetic plantarflexor muscles are related to the biomechanical ankle moment strategy that individuals with chronic stroke used to achieve their greatest walking speeds. Rehabilitation strategies that promote corticomotor balance could potentially improve post-stroke walking mechanics and enhance functional ambulation. Objective: To 1) test the effectiveness of a single session of gait training using functional electrical stimulation (FES) to improve plantarflexor corticomotor symmetry and plantarflexion ankle moment symmetry and 2) determine if changes in corticomotor symmetry relate to changes in ankle moment symmetry within the session...
February 23, 2017: Physical Therapy
https://www.readbyqxmd.com/read/28334406/male-and-female-cervical-spine-biomechanics-and-anatomy-implication-for-scaling-injury-criteria
#2
Narayan Yoganandan, Cameron R Bass, Liming Voo, Frank A Pintar
There is an increased need to develop female-specific injury criteria and anthropomorphic test devices (dummies) for automotive and military environments, especially as women take occupational roles traditionally reserved for men. Although some exhaustive reviews on the biomechanics and injuries of the human spine have appeared in clinical and bioengineering literatures, focus on the difference between male and female cervical spine responses and characteristics has largely been ignored. Current neck injury criteria for automotive dummies for assessing crashworthiness and occupant safety are obtained from animal and human cadaver experiments, computational modeling and human volunteer studies...
March 23, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28331887/android-application-for-determining-surgical-variables-in-brain-tumor-resection-procedures
#3
Rohan C Vijayan, Reid C Thompson, Lola B Chambless, Peter J Morone, Le He, Logan W Clements, Rebekah H Griesenauer, Hakmook Kang, Michael I Miga
The fidelity of image-guided neurosurgical procedures is often compromised due to the mechanical deformations that occur during surgery. In recent work, a framework was developed to predict the extent of this brain shift in brain-tumor resection procedures. The approach uses preoperatively determined surgical variables to predict brain shift and then subsequently corrects the patient's preoperative image volume to more closely match the intraoperative state of the patient's brain. However, a clinical workflow difficulty with the execution of this framework is the preoperative acquisition of surgical variables...
January 2017: Journal of Medical Imaging
https://www.readbyqxmd.com/read/28328629/clinical-biomechanical-and-anatomic-investigation-of-colles-fascia-and-pubic-ramus-periosteum-for-use-during-medial-thighplasty
#4
Martin J Carney, Tim Matatov, Matthew Freeman, John Miller, Rahul Vemula, Jason Schuster, Michael Dancisak, John Lindsey, Guenevere Rae
INTRODUCTION: The medial thighplasty is a procedure where patients may attain superior mobility, hygiene, and cosmesis. Most surgeons use attachment of the superficial fascial system (SFS) of the thigh flap to the Colles fascia, whereas others attach the SFS to the pubic ramus periosteum. Because of a high complication profile, we aim to elucidate the clinical, biomechanical, and anatomic qualities of the Colles fascia versus the pubic ramus periosteum. MATERIALS AND METHODS: We performed a 17-year retrospective review documenting clinical complications, a biomechanical analysis of sutures placed in different tissue layers of the thigh, and a histologic analysis surrounding the ischiopubic ramus...
March 21, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28326347/the-insufficiencies-of-risk-analysis-of-impending-pathological-fractures-in-patients-with-femoral-metastases-a-literature-review
#5
Emir Benca, Janina M Patsch, Winfried Mayr, Dieter H Pahr, Reinhard Windhager
PURPOSE: Pathologic fractures in patients with bone metastases are a common problem in clinical orthopaedic routine. On one hand recognition of metastatic lesions, which are at a high risk of fracture, is essential for timely prophylactic fixation, while on the other hand patients with a low risk of pathologic fractures should be spared from overtreatment. The purpose of this review is to identify all methods for fracture risk evaluation in patients with femoral metastases in the literature and to evaluate their predictive values in clinical applications...
December 2016: Bone Reports
https://www.readbyqxmd.com/read/28325673/lower-limb-dynamics-and-clinical-outcomes-for-habitually-shod-runners-who-transition-to-barefoot-running
#6
Rami Hashish, Sachithra D Samarawickrame, Susan Sigward, Stanley P Azen, George J Salem
OBJECTIVES: Recent investigations have revealed lower vertical loading rates and knee energy absorption amongst experienced barefoot runners relative to those who rear-foot strike (RFS). Although this has led to an adoption of barefoot running amongst many recreational shoe runners, recent investigations indicate that the experienced barefoot pattern is not immediately realized. Therefore, the purpose this investigation was to quantify changes in lower-extremity dynamics and clinical outcomes measures for habitually shod runners who perform a transition to barefoot running...
December 10, 2016: Physical Therapy in Sport
https://www.readbyqxmd.com/read/28321636/the-effect-of-cement-on-hip-stem-fixation-a-biomechanical-study
#7
Talip Çelik, İbrahim Mutlu, Arif Özkan, Yasin Kişioğlu
This study presents the numerical analysis of stem fixation in hip surgery using with/without cement methods since the use of cement is still controversial based on the clinical studies in the literature. Many different factors such as stress shielding, aseptic loosening, material properties of the stem, surgeon experiences etc. play an important role in the failure of the stem fixations. The stem fixation methods, cemented and uncemented, were evaluated in terms of mechanical failure aspects using computerized finite element method...
March 20, 2017: Australasian Physical & Engineering Sciences in Medicine
https://www.readbyqxmd.com/read/28321426/quantitative-anatomic-analysis-of-the-native-ligamentum-teres
#8
Jacob D Mikula, Erik L Slette, Jorge Chahla, Alex W Brady, Renato Locks, Christiano A C Trindade, Matthew T Rasmussen, Robert F LaPrade, Marc J Philippon
BACKGROUND: While recent studies have addressed the biomechanical function of the ligamentum teres and provided descriptions of ligamentum teres reconstruction techniques, its detailed quantitative anatomy remains relatively undocumented. Moreover, there is a lack of consensus in the literature regarding the number and morphology of the acetabular attachments of the ligamentum teres. PURPOSE: To provide a clinically relevant quantitative anatomic description of the native human ligamentum teres...
February 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28320557/study-of-light-scattering-using-c-quant-%C3%A2-in-patients-with-fuchs-endothelial-dystrophy-a-pilot-study
#9
B Castaño-Martín, J Gros-Otero, J Martínez, M Teus
OBJECTIVE: The purpose of this study was to determine the light scattering in patients with Fuchs' endothelial dystrophy without clinically significant corneal oedema, and evaluate its relationship with endothelial cell count, corneal thickness, and corneal biomechanical parameters. MATERIALS AND METHODS: The values of light scattering were measured by C-Quant(®) (Oculus Optikgeräte GmbH, Germany) in 32 eyes of 17 patients diagnosed with Fuchs' endothelial dystrophy without clinically significant corneal oedema...
March 17, 2017: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/28319902/ultra-high-sensitivity-of-the-non-immunological-affinity-of-graphene-oxide-peptide-based-surface-plasmon-resonance-biosensors-to-detect-human-chorionic-gonadotropin
#10
Nan-Fu Chiu, Chia-Tzu Kuo, Ting-Li Lin, Chia-Chen Chang, Chen-Yu Chen
Specific peptide aptamers can be used in place of expensive antibody proteins, and they are gaining increasing importance as sensing probes due to their potential in the development of non-immunological assays with high sensitivity, affinity and specificity for human chorionic gonadotropin (hCG) protein. We combined graphene oxide (GO) sheets with a specific peptide aptamer to create a novel, simple and label-free tool to detect abnormalities at an early stage of pregnancy, a GO-peptide-based surface plasmon resonance (SPR) biosensor...
March 7, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28318603/rupture-risk-in-abdominal-aortic-aneurysms-a-realistic-assessment-of-the-explicit-gpu-approach
#11
V Strbac, D M Pierce, B Rodriguez-Vila, J Vander Sloten, N Famaey
Accurate estimation of peak wall stress (PWS) is the crux of biomechanically motivated rupture risk assessment for abdominal aortic aneurysms aimed to improve clinical outcomes. Such assessments often use the finite element (FE) method to obtain PWS, albeit at a high computational cost, motivating simplifications in material or element formulations. These simplifications, while useful, come at a cost of reliability and accuracy. We achieve research-standard accuracy and maintain clinically applicable speeds by using novel computational technologies...
February 27, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28316962/wiring-techniques-for-the-fixation-of-trochanteric-fragments-during-bipolar-hemiarthroplasty-for-femoral-intertrochanteric-fracture-clinical-study-and-technical-note
#12
Joong-Myung Lee, Yongsuk Cho, Junhyun Kim, Dong-Won Kim
PURPOSE: Femoral intertrochanteric fractures are common in the elderly. Appropriate surgical fixation of trochanteric fracture fragments can restore normal anatomical structure and ambulation, and can aid in the recovery of biomechanical function of the hip. We evaluated clinical outcomes of bipolar hemiarthroplasty using a wiring technique for trochanteric fracture fragment fixation. MATERIALS AND METHODS: From September 2006 to February 2015, a total of 260 cases underwent simultaneous bipolar hemiarthroplasty and wire fixation...
March 2017: Hip & Pelvis
https://www.readbyqxmd.com/read/28315016/biomechanics-of-the-osteoporotic-spine-pain-and-principles-of-training
#13
Guido Schröder, Andreas Knauerhase, Holger S Willenberg, Guenther Kundt, Detlef Wendig, Hans-Christof Schober
INTRODUCTION: A fracture is a clinical manifestation of osteoporosis and is one of the main causes of functional limitations and chronic pain in patients with osteoporosis. Muscle and coordination training are recommended to the patients as general measures. We inquired whether sling training is better than traditional physiotherapy in relieving pain and improving abilities of daily living. METHODS: Fifty patients with osteoporosis were divided into two groups. Group A performed conventional physiotherapy, while Group B performed sling training exercises...
March 17, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28314887/mechanical-strains-passing-through-the-acetabular-labrum-modify-its-shape-during-hip-motion-an-anatomical-study
#14
Matthieu Ollivier, Thomas Le Corroller, Sebastien Parratte, Patrick Chabrand, Jean-Noël Argenson, Olivier Gagey
PURPOSE: The function of the hip labrum during hip motion remains poorly known. Our hypothesis was that acetabular labrum will deform and change its shape during adduction to abduction movement consecutively to variation of strains passing from the acetabulum to the femoral head. An ex vivo anatomical study was conducted to analyse the morphological parameters variation of the mid-portion of the labrum (length, thickness, shape, deformation) as well as femoro-labral strains during hip adduction to abduction movement...
March 17, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28314563/a-biomechanical-approach-to-the-analysis-of-methods-and-procedures-of-bariatric-surgery
#15
Emanuele Luigi Carniel, Alessandro Frigo, Chiara Giulia Fontanella, Giulia Maria De Benedictis, Alessandro Rubini, Luca Barp, Gioela Pluchino, Beatrice Sabbadini, Lino Polese
Bariatric surgery includes a variety of procedures that are performed on obese people and aim at decreasing the intake of food and calories. This goal is usually pursued by reducing stomach capacity and/or absorbing capability. Adjustable gastric banding is the most common and successful operation. In general, bariatric surgical procedures are effective, but are often associated with major complications. Surgical procedure and post-surgical conformation of the stomach are usually defined on clinical and surgical basis only...
March 4, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28306191/biomechanical-markers-and-theoretical-concepts-related-to-haemophilic-ankle-and-subtalar-joint-arthropathy-introducing-the-term-haemophilic-tarsal-pan-arthropathy
#16
REVIEW
S Lobet, A McCarthy, C Hermans, K Peerlinck, G A Matricali, F Staes, K Deschamps
BACKGROUND: Although regular factor replacement can reduce the incidence of joint bleeds and slow down the development of haemophilic arthropathy, the ankle joint remains particularly vulnerable even in children with haemophilia on primary or secondary prophylaxis and is now the primary joint affected. The heterogeneity in the pathoaetiology of haemophilic ankle arthropathy means that the functional consequences of early stage of ankle arthropathy are difficult to define as early morphological and structural changes can be observed in clinically asymptomatic ankles...
March 17, 2017: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/28301825/combined-versus-individual-effects-of-a-valgus-knee-brace-and-lateral-wedge-foot-orthotic-during-stair-use-in-patients-with-knee-osteoarthritis
#17
Rebecca Moyer, Trevor Birmingham, Colin Dombroski, Robert Walsh, J Robert Giffin
The aim of this study was to investigate the combined and individual biomechanical effects of a valgus knee brace and a lateral wedge foot orthotic during stair ascent and descent in patients with knee osteoarthritis (OA). Thirty-five patients with varus alignment and medial knee OA were prescribed a custom valgus knee brace and lateral wedge foot orthotic. Knee angles and moments in the frontal and sagittal planes were determined from 3D gait analysis completed under four randomized conditions: (1) control (no knee brace or foot orthotic), (2) knee brace, (3) foot orthotic, and (4) combined knee brace and foot orthotic...
March 1, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28300644/the-connective-tissue-phenotype-of-glaucomatous-cupping-in-the-monkey-eye-clinical-and-research-implications
#18
REVIEW
Hongli Yang, Juan Reynaud, Howard Lockwood, Galen Williams, Christy Hardin, Luke Reyes, Cheri Stowell, Stuart K Gardiner, Claude F Burgoyne
In a series of previous publications we have proposed a framework for conceptualizing the optic nerve head (ONH) as a biomechanical structure. That framework proposes important roles for intraocular pressure (IOP), IOP-related stress and strain, cerebrospinal fluid pressure (CSFp), systemic and ocular determinants of blood flow, inflammation, auto-immunity, genetics, and other non-IOP related risk factors in the physiology of ONH aging and the pathophysiology of glaucomatous damage to the ONH. The present report summarizes 20 years of technique development and study results pertinent to the characterization of ONH connective tissue deformation and remodeling in the unilateral monkey experimental glaucoma (EG) model...
March 12, 2017: Progress in Retinal and Eye Research
https://www.readbyqxmd.com/read/28300359/influence-of-different-boundary-conditions-in-finite-element-analysis-on-pelvic-biomechanical-load-transmission
#19
Pan Hu, Tao Wu, Hui-Zhi Wang, Xin-Zheng Qi, Jie Yao, Xiao-Dong Cheng, Wei Chen, Ying-Ze Zhang
OBJECTIVE: To observe the effects of boundary conditions and connect conditions on biomechanics predictions in finite element (FE) pelvic models. METHODS: Three FE pelvic models were constructed to analyze the effect of boundary conditions and connect conditions in the hip joint: an intact pelvic model assumed contact of the hip joint on both sides (Model I); and a pelvic model assumed the hip joint connecting surfaces fused together with (Model II) or without proximal femurs (Model III)...
March 16, 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28299282/extracellular-proton-concentrations-impacts-ln229-glioblastoma-tumor-cell-fate-via-differential-modulation-of-surface-lipids
#20
Sebastian John, K C Sivakumar, Rashmi Mishra
BACKGROUND: Glioblastoma multiforme (GBM) is a highly aggressive form of brain cancer with marginal survival rates. GBM extracellular acidosis can profoundly impact its cell fate heterogeneities and progression. However, the molecules and mechanisms that enable GBM tumor cells acid adaptation and consequent cell fate competencies are weakly understood. Since extracellular proton concentrations (pHe) directly intercept the tumor cell plasma membrane, surface lipids must play a crucial role in pHe-dependent tumor cell fate dynamics...
2017: Frontiers in Oncology
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