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Virupakshi Jalihal, Rohit Shankar, William Henley, Mary Parrett, Phil Tittensor, Brendan N McLean, Ammad Ahmed, Josemir W Sander
BACKGROUND: Psychiatric and behavioral side effects (PBSEs) are a major cause of antiepileptic drug (AED) withdrawal. Levetiracetam (LEV) is a recognized first-line AED with good seizure outcomes but recognized with PBSEs. Eslicarbazepine (ESL) is considered to function similarly to an active metabolite of the commonly used carbamazepine (CBZ). Carbamazepine is used as psychotropic medication to assist in various psychiatric illnesses such as mood disorders, aggression, and anxiety. AIM: The aim was to evaluate the psychiatric profile of ESL in people who had LEV withdrawn due to PBSEs in routine clinical practice to see if ESL can be used as a possible alternative to LEV...
March 2018: Epilepsy & Behavior: E&B
Baibing Chen, Hyunmi Choi, Lawrence J Hirsch, Austen Katz, Alexander Legge, Richard Buchsbaum, Kamil Detyniecki
PURPOSE: Psychiatric and behavioral side effects (PBSEs) are common, undesirable effects associated with antiepileptic drug (AED) use. The objective of the study was to compare the PBSE profiles of older and newer AEDs in a large specialty practice-based sample of patients diagnosed with epilepsy. METHODS: As part of the Columbia and Yale AED Database Project, we reviewed patient records including demographics, medical history, AED use, and side effects for 4085 adult patients (age: 18 years) newly started on an AED regimen...
November 2017: Epilepsy & Behavior: E&B
B Chen, K Detyniecki, H Choi, L Hirsch, A Katz, A Legge, R Wong, A Jiang, R Buchsbaum, P Farooque
PURPOSE: The objective of the study was to compare the psychiatric and behavioral side effect (PBSE) profiles of both older and newer antiepileptic drugs (AEDs) in children and adolescent patients with epilepsy. METHOD: We used logistic regression analysis to test the correlation between 83 non-AED/patient related potential predictor variables and the rate of PBSE. We then compared for each AED the rate of PBSEs and the rate of PBSEs that led to intolerability (IPBSE) while controlling for non-AED predictors of PBSEs...
May 2017: European Journal of Paediatric Neurology: EJPN
Rosa María Piñeiro-Albero, Juan Diego Ramos-Pichardo, Antonio Oliver-Roig, Antonio Velandrino-Nicolás, Miguel Richart-Martínez, Ricardo García-de-León-González, Kristen J Wells
BACKGROUND: Only a minority of infants are exclusively breastfed for the recommended 6 months postpartum. Breast-feeding self-efficacy is a mother's confidence in her ability to breastfeed and is predictive of breastfeeding behaviors. The Prenatal Breast-feeding Self-efficacy Scale (PBSES) was developed among English-speaking mothers to measure breastfeeding self-efficacy before delivery. OBJECTIVES: To translate the PBSES into Spanish and assess its psychometric properties...
October 2013: International Journal of Nursing Studies
Wim Van der Elst, Renske Wassenberg, Celeste Meijs, Petra Hurks, Martin Van Boxtel, Jelle Jolles
If the pathological left-handedness theory is valid, left-handed people who also experienced pregnancy and birth stress events (PBSEs) would especially be expected to deviate from the cognitive norm (rather than left-handers in general). This hypothesis was tested in a large sample of healthy children (aged 6.6-15.9 years). Multiple cognitive abilities were assessed, including verbal fluency and working memory. Children with a left lateral preference who also experienced a PBSE did not deviate from the cognitive norm...
June 2011: Journal of Clinical and Experimental Neuropsychology
Wim Van der Elst, Petra P M Hurks, Renske Wassenberg, Celeste J C Meijs, Martin P J Van Boxtel, Jelle Jolles
The pathological left-handedness theory claims that pregnancy and birth stress events (PBSEs) are important risk factors for sinistrality, but previous studies yielded inconclusive results. The aim of the present study was to further evaluate the effect of PBSEs on multiple indicators of lateral preference (i.e., hand, foot, eye, and ear preferences), strength of lateral preferences, and overall lateral consistency in a large nonclinical sample of school-aged children. Results showed that PBSEs occurred in about one third of the sample (mainly forceps use, cesarean section, and preterm birth)...
January 2011: Journal of Clinical and Experimental Neuropsychology
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