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cardiothoracic anesthesia pediatric pain control

D A Rosen, J L Morris, K R Rosen, E R Nelson, R J Steelman, R A Gustafson, J A Wilhelm, C T Chang, J W Thackara, R F Frye
STUDY OBJECTIVE: To determine the pharmacokinetics and preliminary efficacy of nalmefene in children in preventing epidural-induced narcotic side effects. DESIGN: Double-blind, placebo-controlled study. SETTING: University-affiliated children's hospital. PATIENTS: Thirty-four children (aged 2-12 yrs) undergoing cardiothoracic surgery with epidural anesthesia. INTERVENTIONS: Patients were randomized to receive intravenous bolus nalmefene 1 microg/kg or placebo...
July 2000: Pharmacotherapy
K L Peterson, W M DeCampli, N A Pike, R C Robbins, B A Reitz
The use of regional anesthesia (ie, epidural, spinal, or caudal) has been reported in a few small series of children undergoing cardiac surgery, but not in larger studies. In this retrospective, descriptive study, we report the results of the use of regional anesthesia in 220 pediatric cardiac operations. We reviewed the records of children receiving a regional anesthetic for cardiothoracic surgery at Stanford Medical Center between January 1993 and February 1997. All patients were targeted for early tracheal extubation...
May 2000: Anesthesia and Analgesia
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