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https://www.readbyqxmd.com/read/28931994/efficacy-of-ankle-control-balance-training-on-postural-balance-and-gait-ability-in-community-dwelling-older-adults-a-single-blinded-randomized-clinical-trial
#1
Kyeongjin Lee, Yong Woo Lee
[Purpose] This study was conducted to investigate the effects of ankle control balance training (ACBT) on postural balance and gait ability in community-dwelling older adults. [Subjects and Methods] Fifty-four subjects were randomly divided into two groups, with 27 subjects in the ACBT group and 27 subjects in the control group. Subjects in the ACBT group received ACBT for 60 minutes, twice per week for 4 weeks, and all subjects had undergone fall prevention education for 60 minutes, once per week for 4 weeks...
September 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28930381/intraocular-pressure-and-big-bubble-diameter-in-deep-anterior-lamellar-keratoplasty-an-ex-vivo-microscope-integrated-oct-with-heads-up-display-study
#2
Paramjit K Bhullar, Oscar M Carrasco-Zevallos, Alexandria Dandridge, Neel D Pasricha, Brenton Keller, Liangbo Shen, Joseph A Izatt, Cynthia A Toth, Anthony N Kuo
PURPOSE: To investigate the relationship between intraocular pressure (IOP) and big bubble (BB) formation in a model of deep anterior lamellar keratoplasty (DALK). DESIGN: Ex-vivo. METHODS: Corneoscleral buttons from human donors were loaded onto an artificial anterior chamber connected to a column of balanced salt solution. A surgeon-in-training learned to perform DALK via the BB technique using swept-source microscope-integrated optical coherence tomography (SS-MIOCT) with heads-up display (HUD)...
September 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/28921564/machine-specific-quality-assurance-procedure-for-stereotactic-treatments-with-dynamic-couch-rotations
#3
Byron Wilson, Ermias Gete
OBJECTIVE: We present a method in which the treatment couch's accuracy is measured using the electronic portal imaging device (EPID) and a phantom of our own construction. Using this phantom, we were able to quantify the treatment couch walkout, and the rotation angle accuracy for both static and dynamic couch treatments. These measurements were used to provide an accurate measure of the treatment couch isocentre as well as to verify the couch rotation angle recorded in the trajectory log...
September 18, 2017: Medical Physics
https://www.readbyqxmd.com/read/28915003/the-evolution-of-dna-templated-synthesis-as-a-tool-for-materials-discovery
#4
Rachel K O'Reilly, Andrew J Turberfield, Thomas R Wilks
Precise control over reactivity and molecular structure is a fundamental goal of the chemical sciences. Billions of years of evolution by natural selection have resulted in chemical systems capable of information storage, self-replication, catalysis, capture and production of light, and even cognition. In all these cases, control over molecular structure is required to achieve a particular function: without structural control, function may be impaired, unpredictable, or impossible. The search for molecules with a desired function is often achieved by synthesizing a combinatorial library, which contains many or all possible combinations of a set of chemical building blocks (BBs), and then screening this library to identify "successful" structures...
September 15, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28914343/image-guided-percutaneous-removal-of-ballistic-foreign-bodies-secondary-to-air-gun-injuries
#5
Jacob L Rothermund, Andrew J Rabe, Nicholas A Zumberge, James W Murakami, Patrick S Warren, Mark J Hogan
BACKGROUND: Ballistic injuries with retained foreign bodies from air guns is a relatively common problem, particularly in children and adolescents. If not removed in a timely fashion, the foreign bodies can result in complications, including pain and infection. Diagnostic methods to identify the presence of the foreign body run the entire gamut of radiology, particularly radiography, ultrasound (US) and computed tomography (CT). Removal of the foreign bodies can be performed by primary care, emergency, surgical, and radiologic clinicians, with or without imaging guidance...
September 15, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/28906446/a-novel-low-power-consumption-all-fiber-optic-anemometer-with-simple-system-design
#6
Yang Zhang, Fang Wang, Zhihui Duan, Zexu Liu, Zigeng Liu, Zhenlin Wu, Yiying Gu, Changsen Sun, Wei Peng
A compact and low-power consuming fiber-optic anemometer based on single-walled carbon nanotubes (SWCNTs) coated tilted fiber Bragg grating (TFBG) is presented. TFBG as a near infrared in-fiber sensing element is able to excite a number of cladding modes and radiation modes in the fiber and effectively couple light in the core to interact with the fiber surrounding mediums. It is an ideal in-fiber device used in a fiber hot-wire anemometer (HWA) as both coupling and sensing elements to simplify the sensing head structure...
September 14, 2017: Sensors
https://www.readbyqxmd.com/read/28899824/group-and-individual-level-responsiveness-of-the-3-point-berg-balance-scale-and-3-point-postural-assessment-scale-for-stroke-patients
#7
Yi-Jing Huang, Gong-Hong Lin, Shih-Chieh Lee, Yi-Miau Chen, Sheau-Ling Huang, Ching-Lin Hsieh
OBJECTIVE: To examine both group- and individual-level responsiveness of the 3-point Berg Balance Scale (BBS-3P) and 3-point Postural Assessment Scale for Stroke Patients (PASS-3P) in patients with stroke, and to compare the responsiveness of both 3-point measures versus their original measures (BBS and PASS) and their short forms (SFBBS and SFPASS) and between the BBS-3P and PASS-3P. DESIGN: The data were retrieved from a previous study wherein 212 patients were assessed at 14 and 30 days after stroke with the BBS and PASS...
September 9, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28894993/effect-of-growth-hormone-overexpression-on-gastric-evacuation-rate-in-coho-salmon
#8
Jin-Hyoung Kim, Satid Chatchaiphan, Michelle T Crown, Samantha L White, Robert H Devlin
Growth hormone (GH) transgenic (T) coho salmon consistently show remarkably enhanced growth associated with increased appetite and food consumption compared to non-transgenic wild-type (NT) coho salmon. To improve understanding of the mechanism by which GH overexpression mediates food intake and digestion in T fish, feed intake and gastric evacuation rate (over 7 days) were measured in size-matched T and NT coho salmon. T fish displayed greatly enhanced feed intake levels (~ 2.5-fold), and more than 3-fold increase in gastric evacuation rates relative to NT coho salmon...
September 11, 2017: Fish Physiology and Biochemistry
https://www.readbyqxmd.com/read/28880130/the-effects-of-semi-immersive-virtual-reality-therapy-on-standing-balance-and-upright-mobility-function-in-individuals-with-chronic-incomplete-spinal-cord-injury-a-preliminary-study
#9
Chang-Man An, Young-Hyun Park
Background Individuals with chronic incomplete spinal cord injury (iSCI) commonly face persistent balance or mobility impairments. Virtual reality (VR) therapy is a useful rehabilitation approach; however, little is known about its effects in individuals with chronic iSCI. Objective To investigate the effects of semi-immersive VR therapy on standing balance and upright mobility function in individuals with chronic iSCI. Methods Ten subjects with chronic iSCI underwent VR therapy 30 minutes a day, 3 days a week, for 6 weeks...
September 7, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28875690/use-of-fully-covered-self-expanding-metal-stents-for-benign-biliary-etiologies-a-large-multi-center-experience
#10
Abdul Haseeb, Ali Siddiqui, Linda J Taylor, Alyssa Mills, Thomas E Kowalski, David E Loren, Jessica Dahmus, Silpa Yalamanchili, Christopher Cao, Andrew Canakis, Tayebah Mumtaz, Meet Parikh, Douglas G Adler
INTRODUCTION: Fully-covered self-expandable metal stents (FCSEMS) have been used in benign biliary diseases although reported data is limited. These devices are most commonly used to treat biliary leaks, strictures, or both. The aim of this study was to evaluate effectiveness of FCSEMS in treating benign biliary disease and recognize the associated complications. METHODS: We performed a multi-center longitudinal retrospective cohort study of patients with benign biliary disease needing FCSEMS between 2011 and 2016...
September 5, 2017: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/28868293/the-kidney-in-bardet-biedl-syndrome-possible-pathogenesis-of-urine-concentrating-defect
#11
REVIEW
Miriam Zacchia, Valentina Di Iorio, Francesco Trepiccione, Marianna Caterino, Giovambattista Capasso
BACKGROUND: The ciliopathies are a growing number of disorders caused by mutations in genes involved in the function of the primary cilium. Bardet-Biedl syndrome (BBS) belongs to this group of disorders. In this setting, kidney dysfunction is highly variable, and urine concentrating defect, a common feature of multiple ciliopathies, has been described as the most frequent defect. Here we review the mechanism of urine concentration and describe the possible mechanism underling this defect in ciliopathies and especially BBS, based on the current body of literature...
July 2017: Kidney Diseases
https://www.readbyqxmd.com/read/28866428/ultrasound-imaging-transducer-motion-during-standing-postural-tasks-with-and-without-using-transducer-fixator
#12
F Ehsani, M Salavati, A M Arab, M H Dolati
BACKGROUND: Changes in the orientation of ultrasound (US) transducer relative to the body surface during dynamic standing tests can affect US measurements. OBJECTIVE: The purpose of the study was to evaluate ultrasound imaging transducer motion while measuring the lateral abdominal muscle thickness during standing tasks with and without using transducer fixator (TF). DESIGN: Cross-sectional experimental study. METHODS: A digital optical motion analysis system was used to assess the motions of US transducer during double-leg stance in different levels of platform stability of Biodex Balance System (BBS) (static, levels 6 and 3) with and without using TF in 45 healthy individuals...
August 24, 2017: Musculoskeletal Science & Practice
https://www.readbyqxmd.com/read/28859603/effects-of-constraint-induced-movement-therapy-for-lower-limbs-on-measurements-of-functional-mobility-and-postural-balance-in-subjects-with-stroke-a-randomized-controlled-trial
#13
Emília Márcia Gomes de Souza E Silva, Tatiana Souza Ribeiro, Tállyta Camyla Chaves da Silva, Mayara Fabiana Pereira Costa, Fabrícia Azevedo da Costa Cavalcanti, Ana Raquel Rodrigues Lindquist
Abstrato Background: Constraint-induced movement therapy (CIMT) is suggested to reduce functional asymmetry between the upper limbs after stroke. However, there are few studies about CIMT for lower limbs. OBJECTIVE: To examine the effects of CIMT for lower limbs on functional mobility and postural balance in subjects with stroke. METHODS: A 40-day follow-up, single-blind randomized controlled trial was performed with 38 subacute stroke patients (mean of 4.5 months post-stroke)...
August 31, 2017: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/28854348/changing-initial-glaucoma-medical-therapy-increases-healthcare-resource-utilization
#14
Matthew G J Trese, Andrew W Lewis, Taylor S Blachley, Joshua D Stein, Sayoko E Moroi
PURPOSE: To determine the frequency and economic impact of changing initial glaucoma therapy for patients with newly diagnosed open-angle glaucoma (OAG) or ocular hypertension (OHT). METHODS: This retrospective longitudinal cohort study identified individuals within a large managed care network in the United States, who were newly diagnosed with OAG or OHT from 2001 to 2012 and were prescribed either a topical beta blocker (BB) or a prostaglandin analog (PGA). Claims data were analyzed over the 12-month period following their index prescription to determine physician prescribing habits, healthcare resource utilization patterns, and sociodemographic factors which may have contributed to changing the initial treatment strategy...
August 30, 2017: Journal of Ocular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28853232/rate-control-with-beta-blockers-versus-calcium-channel-blockers-in-the-emergency-setting-predictors-of-medication-class-choice-and-associated-hospitalization
#15
Clare L Atzema, Peter C Austin
OBJECTIVES: Rate-control is an important component of the management of patients with atrial fibrillation (AF). Previous studies of emergency department (ED) rate-control have been limited by relatively small sample sizes. We examined the use of beta-blockers (BB) versus non-dihydropyridine calcium channel blockers (CCB) in ED patients from 24 sites, and the associated hospital admission rates. METHODS: In this pre-planned sub-study, we examined chart data on AF patients who visited one of 24 hospital EDs in Ontario, Canada, between April 2008 and March 2009...
August 29, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28852127/bbs4-regulates-the-expression-and-secretion-of-fstl1-a-protein-that-participates-in-ciliogenesis-and-the-differentiation-of-3t3-l1
#16
Victoria Prieto-Echagüe, Sukanya Lodh, Laura Colman, Natalia Bobba, Leonardo Santos, Nicholas Katsanis, Carlos Escande, Norann A Zaghloul, Jose L Badano
Bardet-Biedl syndrome is a model ciliopathy. Although the characterization of BBS proteins has evidenced their involvement in cilia, extraciliary functions for some of these proteins are also being recognized. Importantly, understanding both cilia and cilia-independent functions of the BBS proteins is key to fully dissect the cellular basis of the syndrome. Here we characterize a functional interaction between BBS4 and the secreted protein FSTL1, a protein linked to adipogenesis and inflammation among other functions...
August 29, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28843795/sustainable-magnet-responsive-nanomaterials-for-the-removal-of-arsenic-from-contaminated-water
#17
Roberto Nisticò, Luisella R Celi, Alessandra Bianco Prevot, Luciano Carlos, Giuliana Magnacca, Elena Zanzo, Maria Martin
In this study, chitosan and bio-based substances (BBS) obtained from composted biowaste were used as stabilizers for the synthesis of magnet-sensitive nanoparticles (NPs) via coprecipitation method. A pyrolysis treatment was carried out on both biopolymers at 550°C, and their consequent conversion into a carbon matrix was followed by means of different physicochemical characterization techniques (mainly FTIR spectroscopy and XRD), whereas magnetic properties were evaluated by magnetization curves. The prepared materials were tested in water remediation processes from arsenic (As) species (both inorganic and organic forms)...
August 18, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28826325/comparison-of-the-mini-balance-evaluations-systems-test-with-the-berg-balance-scale-in-relationship-to-walking-speed-and-motor-recovery-post-stroke
#18
Sangeetha Madhavan, Alka Bishnoi
BACKGROUND: The Mini-BESTest is a recently developed balance assessment tool that incorporates challenging dynamic balance tasks. Few studies have compared the psychometric properties of the Mini-BESTest to the commonly used Berg Balance Scale (BBS). However, the utility of these scales in relationship to post stroke walking speeds has not been explored. OBJECTIVES: The purpose of this study was to compare the sensitivity and specificity of the Mini-BESTest and BBS to evaluate walking speeds in individuals with stroke...
August 21, 2017: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/28818460/the-design-and-synthesis-of-a-novel-compound-of-berberine-and-baicalein-that-inhibits-the-efficacy-of-lipid-accumulation-in-3t3-l1-adipocytes
#19
Mengjiao Hao, Zhuoji Guan, Yan Li, Lixian Liu, Xiao Yuan, Ying Gao, Weimin Li
The combination of berberine and baicalein may have a better therapeutic effect against disease. To explore the combined effect of baicalein and berberine in the treatment of obesity, we designed and synthesized a hybrid compound, and its biological activities were evaluated in 3T3-L1 adipocytes. The structures of the berberine-baicalein (BBS) compounds were confirmed by (1)H NMR, (13)C NMR, ultraviolet spectroscopy and high resolution mass spectrometry (HRMS). The present study showed that the IC50 values of the inhibitory effects of baicalein, berberine and BBS against 3T3-L1 cells were 29...
August 9, 2017: Bioorganic & Medicinal Chemistry
https://www.readbyqxmd.com/read/28808579/a-novel-bbs10-mutation-identified-in-a-patient-with-bardet-biedl-syndrome-with-a-violent-emotional-outbreak
#20
Tatsuyuki Ohto, Takashi Enokizono, Ryuta Tanaka, Mai Tanaka, Hisato Suzuki, Aiko Sakai, Kazuo Imagawa, Hiroko Fukushima, Takashi Fukushima, Ryo Sumazaki, Tomoko Uehara, Toshiki Takenouchi, Kenjiro Kosaki
We report a 10-year-old girl with Bardet-Biedl syndrome caused by a novel mutation in the Bardet-Biedl syndrome 10 (BBS10) gene. She had multiple malformations, including a dysmorphic face, postaxial polydactyly, polycystic kidney and amblyopia. She presented with typical BBS features, including intellectual disability with emotional outbursts and mild obesity. Whole-exome sequencing identified compound heterozygous mutations with NM_024685.3:c.1677C>A [p.(Tyr559*)] and c.1974T>G [p.(Tyr658*)]. To our knowledge, the latter mutation has never been reported previously...
2017: Human Genome Variation
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