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https://www.readbyqxmd.com/read/28432935/accelerometry-based-assessment-and-detection-of-early-signs-of-balance-deficits
#1
Heidi Similä, Milla Immonen, Miikka Ermes
Falls are the cause for more than half of the injury-related hospitalizations among older people. Accurate assessment of individuals' fall risk could enable targeted interventions to reduce the risk. This paper presents a novel method for using wearable accelerometers to detect early signs of deficits in balance from gait. Gait acceleration data were analyzed from 35 healthy female participants (73.86±5.40 years). The data were collected with waist-mounted accelerometer and the participants performed three supervised balance tests: Berg Balance Scale (BBS), Timed-Up-and-Go (TUG) and 4m walk...
April 13, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28431174/opportunities-for-exercise-during-pullet-rearing-part-ii-long-term-effects-on-bone-characteristics-of-adult-laying-hens-at-the-end-of-lay
#2
T M Casey-Trott, D R Korver, M T Guerin, V Sandilands, S Torrey, T M Widowski
Osteoporosis in laying hens has been a production and welfare concern for several decades. The objective of this study was to determine whether differing opportunities for exercise during pullet rearing influences long-term bone quality characteristics in end-of-lay hens. A secondary objective was to assess whether differing opportunities for exercise in adult housing systems alters bone quality characteristics in end-of-lay hens. Four flock replicates of 588 Lohmann Selected Leghorn-Lite pullets were reared in either conventional cages (Conv) or an aviary rearing system (Avi) and placed into conventional cages (CC), 30-bird furnished cages (FC-S), or 60-bird furnished cages (FC-L) for adult housing...
April 18, 2017: Poultry Science
https://www.readbyqxmd.com/read/28428846/long-term-and-widespread-changes-in-agricultural-practices-influence-ring-necked-pheasant-abundance-in-california
#3
Peter S Coates, Brianne E Brussee, Kristy B Howe, Joseph P Fleskes, Ian A Dwight, Daniel P Connelly, Matt G Meshriy, Scott C Gardner
Declines in bird populations in agricultural regions of North America and Europe have been attributed to agricultural industrialization, increases in use of agrochemical application, and increased predation related to habitat modification. Based on count data compiled from Breeding Bird Survey (BBS) from 1974 to 2012, Christmas Bird Count (CBC) collected from 1914 to 2013, and hunter data from Annual Game Take Survey (AGTS) for years 1948-2010, ring-necked pheasants (Phasianus colchicus) in California have experienced substantial declines in agricultural environments...
April 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28411364/centriolar-remodeling-underlies-basal-body-maturation-during-ciliogenesis-in-caenorhabditis-elegans
#4
Inna V Nechipurenko, Cristina Berciu, Piali Sengupta, Daniela Nicastro
The primary cilium is nucleated by the mother centriole-derived basal body (BB) via as yet poorly characterized mechanisms. BBs have been reported to degenerate following ciliogenesis in the C. elegans embryo, although neither BB architecture nor early ciliogenesis steps have been described in this organism. In a previous study (Doroquez et al., 2014), we described the three-dimensional morphologies of sensory neuron cilia in adult C. elegans hermaphrodites at high resolution. Here, we use serial section electron microscopy and tomography of staged C...
April 15, 2017: ELife
https://www.readbyqxmd.com/read/28406769/dexamethasone-effect-on-the-expression-of-transforming-growth-factor-%C3%AE-1-smads-signaling-pathway-in-benign-biliary-stricture-fibroblasts-in-rodent
#5
Ke -Yue Li, Cheng -Xian Shi, Jian -Zhao Huang, Ke -Li Tang
OBJECTIVE: To investigate the effects of dexamethasone on transforming growth factor (TGF)-β1/Smads signaling pathway in benign biliary stricture (BBS) fibroblasts. STUDY DESIGN: An experimental study. PLACE AND DURATION OF STUDY: Guizhou Medical University, Guiyang, Guizhou, China, from January to August 2016. METHODOLOGY: Fibroblasts derived from rabbit BBS model were cultured and identified, then treated by different concentration of dexamethasone (0...
March 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28396767/prenatal-diagnosis-of-bardet-biedl-syndrome-in-a-case-of-hyperechogenic-kidneys-clinical-use-of-dna-sequencing
#6
Santiago Garcia-Tizon Larroca, Vangeliya Blagoeva Atanasova, Maria Orera Clemente, Anna Aluja Mendez, Virginia Ortega Abad, Ricardo Perez Fernandez-Pacheco, Juan De León Luis, Francisco Gamez Alderete
Bardet-Biedl syndrome (BBS) is a ciliopathy that is responsible for multiple visceral abnormalities. This disorder is defined by a combination of clinical signs, many of which appear after several years of development. BBS may be suspected antenatally based on routine ultrasound findings of enlarged hyperechogenic kidneys and postaxial polydactyly.
April 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28393567/prognostic-impact-of-heart-rate-in-elderly-with-systolic-heart-failure-and-concomitant-atrial-fibrillation
#7
Salim Barywani, Max Petzold
OBJECTIVE: The present study aimed to investigate the impact of resting heart rate (HR) on 5-year all-cause mortality in patients ≥80 years with heart failure (HF) with reduced ejection fraction (HFrEF) and concomitant atrial fibrillation (AF) after optimal up-titration of beta-blockers (BBs). METHODS: Patients (n = 185) aged ≥80 years with HF and left ventricular ejection fraction ≤40% were included between January 2000 and January 2008 from two university hospitals, Sahlgrenska and Östra and retrospectively studied from January 2 to May 30, 2013...
April 10, 2017: Scandinavian Cardiovascular Journal: SCJ
https://www.readbyqxmd.com/read/28392863/efficacy-of-intravenous-administration-of-landiolol-in-patients-with-acute-heart-failure-and-supraventricular-tachyarrhythmia
#8
Shunsuke Kiuchi, Hiroto Aikawa, Shinji Hisatake, Takayuki Kabuki, Takashi Oka, Shintaro Dobashi, Takahiro Fujii, Takanori Ikeda
BACKGROUND: Patients with acute heart failure (HF) complicated by supraventricular tachyarrhythmia (SVT) often receive continuous intravenous infusion of landiolol or diltiazem for rate control. It is unclear whether the interval from initiation of infusion to commencement of oral beta-blocker (BB) therapy differs for these two drugs. METHODS: From January 2013 to July 2015, 94 consecutive patients were hospitalized for acute HF complicated by SVT. After 35 patients were excluded, the remaining 59 were divided into groups treated with diltiazem or landiolol...
May 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28392324/the-reliability-and-validity-of-the-timed-up-and-go-motor-test-for-people-with-chronic-stroke
#9
Peggy P K Chan, Joyce I F Si Tou, Mimi M Y Tse, Shamay S M Ng
OBJECTIVES: To examine: (1) the intra-rater, inter-rater and test-retest reliabilities of the timed up and go (motor) test (TUGmotor) in terms of the number of steps taken and completion time with a chronic stroke population; (2) the relationship between stroke-specific impairments and the number of steps taken in the test and the completion time; (3) the minimal detectable change in TUGmotor times; and (4) the cut-off time which best discriminates the performance of people with stroke from that of healthy older adults...
April 6, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28382812/cognitive-effects-of-weight-shifting-controlled-exergames-in-patients-with-chronic-stroke-a-pilot-randomized-comparison-trial
#10
Jen-Wen Hung, Chiung-Xia Chou, Hsueh-Feng Chang, Wen-Chi Wu, Yen-Wei Hsieh, Po-Chih Chen, Min-Yuan Yu, Chiung-Chih Chang, Jr-Rung Lin
BACKGROUND: The exergaming training involves motor as well as cognitive stimulation. Although exergame studies have been reported to have benefits in motor function, the effects of exergames on improving cognitive function remain inconclusive. Moreover, no study has been reported in stroke patients. AIM: The objective of this study was to compare the cognitive effects of 2 weight-shifting controlled exergaming systems and conventional weight- shifting training in patients with chronic stroke...
April 4, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28379533/opportunities-for-exercise-during-pullet-rearing-part-i-effect-on-the-musculoskeletal-characteristics-of-pullets
#11
T M Casey-Trott, D R Korver, M T Guerin, V Sandilands, S Torrey, T M Widowski
Increased load-bearing exercise improves bone quality characteristics in a variety of species, including laying hens. Providing increased opportunities for exercise during the pullet rearing phase, a period of substantial musculoskeletal growth, offers a proactive approach to reducing osteoporosis by improving bone composition. The main objective of this study was to determine whether differing opportunities for exercise during rearing influences pullet musculoskeletal characteristics. Two flock replicates of 588 Lohmann Selected Leghorn-Lite pullets were reared in either standard, conventional cages (Conv) or an aviary rearing system (Avi) from day-old chicks until 16 wk of age...
March 31, 2017: Poultry Science
https://www.readbyqxmd.com/read/28375093/research-on-the-influence-factors-of-the-fall-efficiency-of-the-hospitalized-geriatric-patients-with-cerebrovascular-diseases
#12
Weili Li, Ruilian Cheng
To investigate the fall efficiency and its influence factors of the hospitalized geriatric patients with cerebrovascular diseases. The Modified Fall Efficacy Scale (MFES), Morse Fall Risk Assessment Scales (MFS), Berg Balance Scale (BBS) and Tinetti Gait Analysis (TGA) were adopted and the combined ways of questionnaires and observation were utilized to investigate the 113 hospitalized geriatric patients with cerebrovascular diseases. The fall efficiency of the geriatric patients with cerebrovascular diseases were 7...
November 2016: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28371940/comparison-of-the-berg-balance-scale-and-the-mini-bestest-for-assessing-balance-in-ambulatory-people-with-spinal-cord-injury-validation-study
#13
Vivien Jørgensen, Arve Opheim, Alexandra Halvarsson, Erika Franzén, Kirsti Skavberg Roaldsen
Background.: The Berg Balance Scale (BBS) has several constraints-ceiling effect, low responsiveness, and uncertain predictability of falls-in neurological populations. The Mini-BESTest, which has not yet been validated in spinal cord injury (SCI) populations, has shown no ceiling effect, slightly better responsiveness, and could in some neurological populations predict falls. Objective.: Validate and compare psychometric performances of the BBS and Mini-BESTest in individuals with chronic SCI...
March 24, 2017: Physical Therapy
https://www.readbyqxmd.com/read/28371235/insulin-regulates-bbs4-during-adipogenesis
#14
Netta Nahum, Efrat Forti, Olga Aksanov, Ruth Birk
Bardet-Biedl syndrome (BBS) is a pleiotropic autosomal recessive disorder associated with marked obesity, increased susceptibility to insulin resistance and type 2 diabetes. However, it is unknown whether the link between BBS and diabetes is indirect or direct. Adipogenesis and adipocyte function are regulated by hormonal stimuli, with insulin and insulin growth factor (IGF) playing an important role both in normal and impaired conditions. We have previously shown augmented transcript levels of BBS genes upon induction of adipogenesis...
April 3, 2017: IUBMB Life
https://www.readbyqxmd.com/read/28363921/evidence-of-potential-bias-in-a-comparison-of-%C3%AE-blockers-and-calcium-channel-blockers-in-patients-with-chronic-obstructive-pulmonary-disease-and-acute-coronary-syndrome-results-of-a-multinational-study
#15
Yaa-Hui Dong, Matthew Alcusky, Vittorio Maio, Jun Liu, Mengdan Liu, Li-Chiu Wu, Chia-Hsuin Chang, Mei-Shu Lai, Joshua J Gagne
OBJECTIVES: A number of observational studies have reported that, in patients with chronic obstructive pulmonary disease (COPD), β blockers (BBs) decrease risk of mortality and COPD exacerbations. To address important methodological concerns of these studies, we compared the effectiveness and safety of cardioselective BBs versus non-dihydropyridine calcium channel blockers (non-DHP CCBs) in patients with COPD and acute coronary syndromes (ACS) using a propensity score (PS)-matched, active comparator, new user design...
March 31, 2017: BMJ Open
https://www.readbyqxmd.com/read/28352024/anesthetic-management-of-two-cases-of-bardet-biedl-syndrome-for-renal-transplantation
#16
Kalpana S Vora, Manisha P Modi, Bina P Butala, Veena R Shah
Bardet-Biedl syndrome (BBS) is a multisystem autosomal recessive disorder with clinical and genetic heterogeneity. It is a type of ciliopathy characterized by retinal dystrophy, central obesity, polydactyly, cognitive impairment, and gonadal and renal dysgenesis. It has been suggested that the involved proteins attach to the basal body of ciliated cells making this a disorder of ciliary dysfunction. We report two cases of typical BBS in a 17-year-old female and 29-year-old male patient, who presented for live-related renal transplant...
March 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28325523/total-management-of-chronic-obstructive-pulmonary-disease-copd-as-an-independent-risk-factor-for-cardiovascular-disease
#17
REVIEW
Katsuya Onishi
Patients with cardiovascular disease (CVD) often have multiple comorbid conditions that may interact with each other, confound the choice of treatments, and reduce mortality. Chronic obstructive pulmonary disease (COPD) is one of the most important comorbidities of CVD, which causes serious consequences in patients with ischemic heart disease, stroke, arrhythmia, and heart failure. COPD shares common risk factors such as tobacco smoking and aging with CVD, is associated with less physical activity, and produces systemic inflammation and oxidative stress...
March 18, 2017: Journal of Cardiology
https://www.readbyqxmd.com/read/28300379/the-spatial-accuracy-of-two-frameless-linear-accelerator-based-systems-for-single-isocenter-multitarget-cranial-radiosurgery
#18
Gary A Ezzell
Single-isocenter, multitarget cranial stereotactic radiosurgery (SRS) is more efficient than using an isocenter for each target, but spatial positioning uncertainties can be magnified at locations away from the isocenter. This study reports on the spatial accuracy of two frameless, linac-based SRS systems for multitarget, single-isocenter SRS as a function of distance from the isocenter. One system uses the ExacTrac platform for image guidance and the other localizes with cone beam computed tomography (CBCT)...
March 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28296306/a-novel-phantom-and-procedure-providing-submillimeter-accuracy-in-daily-qa-tests-of-accelerators-used-for-stereotactic-radiosurgery
#19
Ivan A Brezovich, Richard A Popple, Jun Duan, Sui Shen, Xingen Wu, Sidi Benhabib, Mi Huang, Rex A Cardan
Stereotactic radiosurgery (SRS) places great demands on spatial accuracy. Steel BBs used as markers in quality assurance (QA) phantoms are clearly visible in MV and planar kV images, but artifacts compromise cone-beam CT (CBCT) isocenter localization. The purpose of this work was to develop a QA phantom for measuring with sub-mm accuracy isocenter congruence of planar kV, MV, and CBCT imaging systems and to design a practical QA procedure that includes daily Winston-Lutz (WL) tests and does not require computer aid...
July 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28293482/psychometric-properties-of-brief-balance-evaluation-systems-test-brief-bestest-in-evaluating-balance-performance-in-individuals-with-chronic-stroke
#20
Meizhen Huang, Marco Y C Pang
OBJECTIVE: To examine the psychometric properties of the Brief-Balance Evaluation Systems Test (Brief-BESTest) in individuals with chronic stroke. MATERIALS AND METHODS: This was an observational study with repeated measurements involving 50 participants with chronic stroke [mean (SD) age: 59.2 (7.3) years]. Each participant with stroke was evaluated with the Brief-BESTest, Berg balance scale (BBS), Postural Assessment Scale for Stroke Patients (PASS), Fugl-Meyer Motor Assessment (FMA), Chedoke-McMaster Stroke Assessment (CMSA), Montreal Cognitive Assessment (MoCA), and Geriatric Depression Scale (GDS)...
March 2017: Brain and Behavior
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