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https://www.readbyqxmd.com/read/28078789/-breastfeeding-without-baby-a-longitudinal-qualitative-investigation-of-how-mothers-perceive-feel-about-and-practice-human-milk-expression
#1
Julia P Felice, Sheela R Geraghty, Caroline W Quaglieri, Rei Yamada, Adriana J Wong, Kathleen M Rasmussen
Most American mothers who produce human milk (HM) now pump in place of some or all feeding at the breast, and most American infants are now fed pumped HM. We aimed to investigate mothers' perceptions of, attitudes toward, and practices for pumping and providing pumped HM. Results related to pumping are reported here. We conducted in-depth, semi-structured interviews among a diverse sample of 20 mothers who pumped, following each from pregnancy through infant HM-feeding cessation up to 1 year postpartum. Data were analyzed using thematic analysis with Atlas...
January 12, 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/28061033/breastfeeding-infants-with-ankyloglossia-insight-into-mothers-experiences
#2
Kevin Wong, Punam Patel, Michael B Cohen, Jessica R Levi
INTRODUCTION: Breastfeeding difficulty from ankyloglossia can affect both the mother and baby in a breastfeeding dyad. With renewed emphasis in today's culture on breast milk, mothers may feel increasing pressure to breastfeed, and the inability for some to do so may cause significant distress. Recently, online parenting forums have seen exponential growth; these forums allow mothers to connect with peers undergoing similar life transitions. The purpose of this study was to review online discussions regarding ankyloglossia to understand mothers' experiences with breastfeeding...
January 6, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/28049520/perceptions-and-experiences-of-using-a-nipple-shield-among-parents-and-staff-an-ethnographic-study-in-neonatal-units
#3
Renée Flacking, Fiona Dykes
BACKGROUND: Preterm infants have an immature sucking behavior and the capacity to be exclusively breastfed may be reduced for a period of weeks or months, depending on gestational age. Nipple shields have been used, not only as a device to help mothers with sore nipples, but also to facilitate the infant's latch on to the breast. However, the benefits of using nipple shields have been debated. The aim of this study was to explore perceptions and experiences of using a nipple shield among parents and staff in neonatal units in Sweden and England...
January 3, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28034726/comparison-of-linear-spatial-filters-for-identifying-oscillatory-activity-in-multichannel-data
#4
REVIEW
Michael X Cohen
BACKGROUND: Large-scale synchronous neural activity produces electrical fields that can be measured by electrodes outside the head, and volume conduction ensures that neural sources can be measured by many electrodes. However, most data analyses in M/EEG research are univariate, meaning each electrode is considered as a separate measurement. Several multivariate linear spatial filtering techniques have been introduced to the cognitive electrophysiology literature, but these techniques are not commonly used; comparisons across filters would be beneficial to the field...
December 27, 2016: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/28027445/efficacy-of-an-osteopathic-treatment-coupled-with-lactation-consultations-for-infants-biomechanical-sucking-difficulties
#5
Juliette Herzhaft-Le Roy, Marianne Xhignesse, Isabelle Gaboury
BACKGROUND: Despite well-known recommendations from national and international bodies including the World Health Organization, few mothers achieve the goal of breastfeeding exclusively for 6 months. Half of mothers stop breastfeeding due to biomechanical issues in the first month, despite increasing support from lactation consultants. Osteopaths worldwide work with these babies, but there is little empirical evidence for this type of treatment. Research aim: This study aimed to determine the efficacy of an osteopathic treatment coupled with usual lactation consultations on infants' ability to latch...
December 1, 2016: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/28024377/kinetics-of-t3-dna-ligase-catalyzed-phosphodiester-bond-formation-measured-using-the-%C3%AE-hemolysin-nanopore
#6
Cherie S Tan, Jan Riedl, Aaron M Fleming, Cynthia J Burrows, Henry S White
The latch region of the wild-type α-hemolysin (α-HL) protein channel can be used to distinguish single base modifications in double-stranded DNA (dsDNA) via ion channel measurements upon electrophoretic capture of dsDNA in the vestibule of α-HL. Herein, we investigated the use of the latch region to detect a nick in the phosphodiester DNA backbone. The presence of a nick in the phosphodiester backbone of one strand of the duplex results in a significant increase in both the blockade current and noise level relative to the intact duplex...
December 27, 2016: ACS Nano
https://www.readbyqxmd.com/read/27942650/qsars-for-phenols-and-phenolates-oxidation-potential-as-a-predictor-of-reaction-rate-constants-with-photochemically-produced-oxidants
#7
William A Arnold, Yan Oueis, Meghan O'Connor, Johanna E Rinaman, Miranda G Taggart, Rachel E McCarthy, Kimberley A Foster, Douglas E Latch
Quantitative structure-activity relationships (QSARs) for prediction of the reaction rate constants of phenols and phenolates with three photochemically produced oxidants, singlet oxygen, carbonate radical, and triplet excited state sensitizers/organic matter, are developed. The predictive variable is the one-electron oxidation potential (E1), which is calculated for each species using density functional theory. The reaction rate constants are obtained from the literature, and for singlet oxygen, are augmented with new experimental data...
December 12, 2016: Environmental Science. Processes & Impacts
https://www.readbyqxmd.com/read/27917833/crystal-structure-of-the-toxin-msmeg_6760-the-structural-homolog-of-mycobacterium-tuberculosis-rv2035-a-novel-type-ii-toxin-involved-in-the-hypoxic-response
#8
R Alexandra Bajaj, Mark A Arbing, Annie Shin, Duilio Cascio, Linda Miallau
The structure of Msmeg_6760, a protein of unknown function, has been determined. Biochemical and bioinformatics analyses determined that Msmeg_6760 interacts with a protein encoded in the same operon, Msmeg_6762, and predicted that the operon is a toxin-antitoxin (TA) system. Structural comparison of Msmeg_6760 with proteins of known function suggests that Msmeg_6760 binds a hydrophobic ligand in a buried cavity lined by large hydrophobic residues. Access to this cavity could be controlled by a gate-latch mechanism...
December 1, 2016: Acta Crystallographica. Section F, Structural Biology Communications
https://www.readbyqxmd.com/read/27898210/the-role-of-early-maternal-support-in-balancing-full-time-work-and-infant-exclusive-breastfeeding-a-qualitative-study
#9
Lea Pounds, Christopher M Fisher, Debora Barnes-Josiah, Jason D Coleman, R Craig Lefebvre
INTRODUCTION: Support of others is a key factor for mothers who choose to breastfeed their infants, including those who balance work outside the home and breastfeeding. However, little research has been done to understand how maternal support during the postpartum period impacts mothers' ability to later balance work and breastfeeding, in particular full-time work and exclusive breastfeeding. The results of this qualitative study indicate that the timing of support plays a key role in mothers' ability to successfully overcome barriers during the early postpartum period, thus building maternal self-efficacy in addressing problems encountered when they return to work...
November 29, 2016: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/27862522/high-gene-flow-in-the-american-badger-overrides-habitat-preferences-and-limits-broadscale-genetic-structure
#10
E M Kierepka, E K Latch
Habitat associations are a function of habitat preferences and dispersal capabilities, both of which can influence how species responded to Quaternary climatic changes and contemporary habitat heterogeneity. Predicting resultant genetic structure is not always straightforward, especially in species where high dispersal potential and habitat preferences yield opposing predictions. The American badger has high dispersal capabilities that predict widespread panmixia, but avoids closed-canopy forests and clay soils, which could restrict gene flow and create ecologically based population genetic structure...
December 2016: Molecular Ecology
https://www.readbyqxmd.com/read/27843833/effect-of-mother-infant-pair-s-latch-on-position-on-child-s-health-a-lesson-for-nursing-care
#11
Harshdeep Joshi, Pushpendra Magon, Sunil Raina
BACKGROUND: Effective breastfeeding is a function of the proper positioning of mother and baby and attachment of child to the mother's breast. Positioning of the baby's body is important for good attachment and successful breastfeeding. The study was planned to assess mother-infant pair latch on position and its impact on health status of the child. MATERIALS AND METHODS: It was community-based cross-sectional study conducted among 1267 children between age group of 0-24 months in the urban and rural field practice areas of the Department of Community Medicine, Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, Ambala, Haryana...
April 2016: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/27828726/early-breast-milk-pumping-intentions-among-postpartum-women
#12
Yiska Loewenberg Weisband, Sarah A Keim, Lisa M Keder, Sheela R Geraghty, Maria F Gallo
INTRODUCTION: Milk expression has become common, but little is known about women's intentions and motivations for pumping. Our objectives were to measure, among newly postpartum women, intentions related to breast milk feeding and pumping, reasons for intending to pump, and timing of pumping initiation. METHODS: We conducted a cross-sectional study at a large university hospital in 2015 using a convenience sample of 100 women before their discharge following delivery, who intended to feed their infant breast milk for at least 6 months...
November 9, 2016: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/27806276/the-ph-dependent-trigger-in-diphtheria-toxin-t-domain-comes-with-a-safety-latch
#13
Mykola V Rodnin, Jing Li, Michael L Gross, Alexey S Ladokhin
Protein-side-chain protonation, coupled to conformational rearrangements, is one way of regulating physiological function caused by changes in protein environment. Specifically, protonation of histidine residues has been implicated in pH-dependent conformational switching in several systems, including the diphtheria toxin translocation (T) domain, which is responsible for the toxin's cellular entry via the endosomal pathway. Our previous studies a) identified protonation of H257 as a major component of the T domain's conformational switch and b) suggested the possibility of a neighboring H223 acting as a modulator, affecting the protonation of H257 and preventing premature conformational changes outside the endosome...
November 1, 2016: Biophysical Journal
https://www.readbyqxmd.com/read/27759411/tongue-tie-assessment-clinical-aspects-and-a-new-diode-laser-technique-for-its-management
#14
R Crippa, M Paglia, F Ferrante, A Ottonello, F Angiero
: BACKGROUND Often breastfeeding problems experienced by mothers and their babies may be attributed to the abnormal attachment of the infant's tongue (ankyloglossia) and/or maxillary lip-tie. Proper breastfeeding depends upon an infant's ability to correctly latch onto its mother's breast. If born with oral soft tissue abnormalities such as tongue-tie or lip-tie, it may be almost impossible for the infant to breastfeed. During the oral evaluation of an infant presenting with breastfeeding problems, one factor that is often overlooked and undiagnosed - and thus untreated - is the attachment of the upper lip to the maxillary gingival tissue...
September 2016: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/27754572/effects-of-pacifier-use-on-transition-to-full-breastfeeding-and-sucking-skills-in-preterm-infants-a-randomised-controlled-trial
#15
Vildan Kaya, Aynur Aytekin
AIMS AND OBJECTIVES: To determine the effects of pacifier use on transition to full breastfeeding and sucking skills in preterm infants. BACKGROUND: Feeding problems in preterm infants cause delays in hospital discharge, extend mother-infant reunification, and increase medical cost. Nutritive sucking skills of preterm infants may develop by improving non-nutritive sucking skills and increasing sucking experiences. DESIGN: A prospective, randomised controlled trial conducted in the Eastern Turkey...
October 18, 2016: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/27729058/unmanned-aerial-vehicles-drones-in-out-of-hospital-cardiac-arrest
#16
A Claesson, D Fredman, L Svensson, M Ringh, J Hollenberg, P Nordberg, M Rosenqvist, T Djarv, S Österberg, J Lennartsson, Y Ban
BACKGROUND: The use of an automated external defibrillator (AED) prior to EMS arrival can increase 30-day survival in out-of-hospital cardiac arrest (OHCA) significantly. Drones or unmanned aerial vehicles (UAV) can fly with high velocity and potentially transport devices such as AEDs to the site of OHCAs. The aim of this explorative study was to investigate the feasibility of a drone system in decreasing response time and delivering an AED. METHODS: Data of Global Positioning System (GPS) coordinates from historical OHCA in Stockholm County was used in a model using a Geographic Information System (GIS) to find suitable placements and visualize response times for the use of an AED equipped drone...
October 12, 2016: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://www.readbyqxmd.com/read/27714007/multiple-actuation-microvalves-in-wax-microfluidics
#17
María Díaz-González, César Fernández-Sánchez, Antonio Baldi
Microvalves are an essential component of microfluidic devices. In this work, a low-consumption (<35 mJ), fast-response (<0.3 s), small footprint (<0.5 mm(2)) wax microvalve capable of multiple actuation is described. This phase-change microvalve is electrically controlled, simple to operate and can be easily fabricated as a fully integrated element of wax microfluidic devices through a special decal-transfer microlithographic process. The valve is inherently latched and leak-proof to at least 100 kPa...
October 5, 2016: Lab on a Chip
https://www.readbyqxmd.com/read/27711888/energetics-of-base-flipping-at-a-dna-mismatch-site-confined-at-the-latch-constriction-of-%C3%AE-hemolysin
#18
Robert P Johnson, Rukshan T Perera, Aaron M Fleming, Cynthia J Burrows, Henry S White
Unique, two-state modulating current signatures are observed when a cytosine-cytosine mismatch pair is confined at the 2.4 nm latch constriction of the α-hemolysin (αHL) nanopore. We have previously speculated that the modulation is due to base flipping at the mismatch site. Base flipping is a biologically significant mechanism in which a single base is rotated out of the DNA helical stack by 180°. It is the mechanism by which enzymes are able to access bases for repair operations without disturbing the global structure of the helix...
December 12, 2016: Faraday Discussions
https://www.readbyqxmd.com/read/27698146/a-competing-hydrophobic-tug-on-l596-to-the-membrane-core-unlatches-s4-s5-linker-elbow-from-trp-helix-and-allows-trpv4-channel-to-open
#19
Jinfeng Teng, Stephen H Loukin, Andriy Anishkin, Ching Kung
We have some generalized physical understanding of how ion channels interact with surrounding lipids but few detailed descriptions on how interactions of particular amino acids with contacting lipids may regulate gating. Here we discovered a structure-specific interaction between an amino acid and inner-leaflet lipid that governs the gating transformations of TRPV4 (transient receptor potential vanilloid type 4). Many cation channels use a S4-S5 linker to transmit stimuli to the gate. At the start of TRPV4's linker helix is leucine 596...
October 18, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27685101/radiation-leakage-dose-from-elekta-electron-collimation-system
#20
Garrett M Pitcher, Kenneth R Hogstrom, Robert L Carver
This study provided baseline data required for a greater project, whose objective was to design a new Elekta electron collimation system having significantly lighter electron applicators with equally low out-of field leakage dose. Specifically, off-axis dose profiles for the electron collimation system of our uniquely configured Elekta Infinity accelerator with the MLCi2 treatment head were measured and calculated for two primary purposes: 1) to evaluate and document the out-of-field leakage dose in the patient plane and 2) to validate the dose distributions calculated using a BEAMnrc Monte Carlo (MC) model for out-of-field dose profiles...
September 8, 2016: Journal of Applied Clinical Medical Physics
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