keyword
MENU ▼
Read by QxMD icon Read
search

Wachter

keyword
https://www.readbyqxmd.com/read/27911540/two-color-coherent-control-of-femtosecond-above-threshold-photoemission-from-a-tungsten-nanotip
#1
Michael Förster, Timo Paschen, Michael Krüger, Christoph Lemell, Georg Wachter, Florian Libisch, Thomas Madlener, Joachim Burgdörfer, Peter Hommelhoff
We demonstrate coherent control of multiphoton and above-threshold photoemission from a single solid-state nanoemitter driven by a fundamental and a weak second harmonic laser pulse. Depending on the relative phase of the two pulses, electron emission is modulated with a contrast of the oscillating current signal of up to 94%. Electron spectra reveal that all observed photon orders are affected simultaneously and similarly. We confirm that photoemission takes place within 10 fs. Accompanying simulations indicate that the current modulation with its large contrast results from two interfering quantum pathways leading to electron emission...
November 18, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/27881833/apixaban-for-treatment-of-embolic-stroke-of-undetermined-source-atticus-randomized-trial-rationale-and-study-design
#2
Tobias Geisler, Sven Poli, Christoph Meisner, Juergen Schreieck, Christine S Zuern, Thomas Nägele, Johannes Brachmann, Werner Jung, Georg Gahn, Elisabeth Schmid, Hansjörg Bäezner, Timea Keller, Gabor C Petzold, Jan-Wilko Schrickel, Jan Liman, Rolf Wachter, Frauke Schön, Martin Schabet, Alfred Lindner, Albert C Ludolph, Hubert Kimmig, Sebastian Jander, Uwe Schlegel, Meinrad Gawaz, Ulf Ziemann
RATIONALE: Optimal secondary prevention of embolic stroke of undetermined source is not established. The current standard in these patients is acetylsalicylic acid, despite high prevalence of yet undetected paroxysmal atrial fibrillation. AIM: The ATTICUS randomized trial is designed to determine whether the factor Xa inhibitor apixaban administered within 7 days after embolic stroke of undetermined source, is superior to acetylsalicylic acid for prevention of new ischemic lesions documented by brain magnetic resonance imaging within 12 months after index stroke...
November 23, 2016: International Journal of Stroke: Official Journal of the International Stroke Society
https://www.readbyqxmd.com/read/27879032/altered-expression-of-brg1-and-histone-demethylases-and-aberrant-h3k4-methylation-in-less-developmentally-competent-embryos-at-the-time-of-embryonic-genome-activation
#3
W G Glanzner, A Wachter, A R S Coutinho, M S Albornoz, R Duggavathi, P B D Gonçalves, V Bordignon
Epigenetics is a fundamental regulator underlying many biological functions, such as development and cell differentiation. Epigenetic modifications affect key chromatin regulation, including transcription and DNA repair, which are critical for normal embryo development. In this study, we profiled the expression of epigenetic modifiers and patterns of epigenetic changes in porcine embryos around the period of embryonic genome activation (EGA). We observed that Brahma-related gene 1 (BRG1) and Lysine demethylase 1A (KDM1A), which can alter the methylation status of lysine 4 in histone 3 (H3K4), localize to the nucleus at Days 3-4 of development...
November 23, 2016: Molecular Reproduction and Development
https://www.readbyqxmd.com/read/27877025/medication-knowledge-of-patients-hospitalized-for-heart-failure-at-admission-and-after-discharge
#4
Florian Custodis, Franziska Rohlehr, Angelika Wachter, Michael Böhm, Martin Schulz, Ulrich Laufs
BACKGROUND: A substantial aspect of health literacy is the knowledge of prescribed medication. In chronic heart failure, incomplete intake of prescribed drugs (medication non-adherence) is inversely associated with clinical prognosis. Therefore, we assessed medication knowledge in a cohort of patients with decompensated heart failure at hospital admission and after discharge in a prospective, cross-sectional study. METHODS: One hundred and eleven patients presenting at the emergency department with acute decompensated heart failure were included (mean age 78...
2016: Patient Preference and Adherence
https://www.readbyqxmd.com/read/27876229/temporal-trends-of-chlorinated-paraffins-and-polychlorinated-biphenyls-in-swiss-soils
#5
Christian Bogdal, Nadja Niggeler, Juliane Glüge, Pascal S Diefenbacher, Daniel Wächter, Konrad Hungerbühler
Persistent organic pollutants (POPs), such as polychlorinated biphenyls (PCBs), are ubiquitous environmental contaminants that have been targeted by national regulations since the 1970-1980s, followed in 2004 by the worldwide regulation under the Stockholm Convention on POPs. However, concerns are growing regarding the emergence of additional POP-like substances, such as chlorinated paraffins (CPs), which have particularly large production volumes. Whereas short-chain CPs (SCCPs) have recently been restricted in Europe and are currently under evaluation for inclusion into the Stockholm Convention, medium-chain CPs (MCCPs) have received little attention...
November 18, 2016: Environmental Pollution
https://www.readbyqxmd.com/read/27875777/does-pelvic-floor-muscle-contraction-early-after-delivery-cause-perineal-pain-in-postpartum-women
#6
Hedwig Neels, Stefan De Wachter, Jean-Jacques Wyndaele, Michel Wyndaele, Alexandra Vermandel
OBJECTIVE: Pelvic floor muscle training is effective and necessary in the prevention and treatment of pelvic floor dysfunction during pregnancy and after childbirth. But because of the high prevalence of perineal pain observed in women after childbirth, many women and caregivers fear to start pelvic floor muscle training immediately after childbirth. However, it is unknown whether pelvic floor muscle contractions (PFMC) provoke perineal pain in women shortly after childbirth. Therefore, the main objective is to study whether PFMC performed immediately after childbirth is painful or not...
November 11, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27869312/the-effect-of-emg-biofeedback-assisted-pelvic-floor-muscle-therapy-on-symptoms-of-the-overactive-bladder-syndrome-in-women-a-randomized-controlled-trial
#7
Jeroen C Voorham, Stefan De Wachter, Tine W L Van den Bos, Hein Putter, Guus A Lycklama À Nijeholt, Petra J Voorham-van der Zalm
AIMS: The overactive bladder syndrome (OAB) is defined as urinary urgency, usually accompanied by frequency and nocturia, with or without urgency urinary incontinence. Biofeedback-assisted pelvic muscle therapy (BAPFMT) is a first-line treatment option for OAB. The aims of this study were to determine the efficacy and effectiveness of BAPFMT on symptoms of OAB after 9 weeks of treatment and to detect changes EMG activity of individual pelvic floor muscles (PFM) with the MAPLe. METHODS: Patients were randomly divided into an intervention group that received BAPFMT with the MAPLe or into a control group which received only toilet behavior and lifestyle instructions...
November 21, 2016: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/27845720/a-novel-application-for-low-frequency-electrochemical-impedance-spectroscopy-as-an-online-process-monitoring-tool-for-viable-cell-concentrations
#8
Christoph Slouka, David J Wurm, Georg Brunauer, Andreas Welzl-Wachter, Oliver Spadiut, Jürgen Fleig, Christoph Herwig
New approaches in process monitoring during industrial fermentations are not only limited to classical pH, dO₂ and offgas analysis, but use different in situ and online sensors based on different physical principles to determine biomass, product quality, lysis and far more. One of the very important approaches is the in situ accessibility of viable cell concentration (VCC). This knowledge provides increased efficiency in monitoring and controlling strategies during cultivations. Electrochemical impedance spectroscopy-EIS-is used to monitor biomass in a fermentation of E...
November 11, 2016: Sensors
https://www.readbyqxmd.com/read/27803310/alternative-splicing-substantially-diversifies-the-transcriptome-during-early-photomorphogenesis-and-correlates-with-the-energy-availability-in-arabidopsis
#9
Lisa Hartmann, Philipp Drewe-Boß, Theresa Wießner, Gabriele Wagner, Sascha Geue, Hsin-Chieh Lee, Dominik M Obermüller, Andre Kahles, Jonas Behr, Fabian H Sinz, Gunnar Rätsch, Andreas Wachter
Plants use light as source of energy and information to detect diurnal rhythms and seasonal changes. Sensing changing light conditions is critical to adjust plant metabolism and to initiate developmental transitions. Here we analyzed transcriptome-wide alterations in gene expression and alternative splicing (AS) of etiolated seedlings undergoing photomorphogenesis upon exposure to blue, red, or white light. Our analysis revealed massive transcriptome reprograming as reflected by differential expression of ~20% of all genes and changes in several hundred AS events...
November 1, 2016: Plant Cell
https://www.readbyqxmd.com/read/27798226/development-of-a-high-value-care-culture-survey-a-modified-delphi-process-and-psychometric-evaluation
#10
Reshma Gupta, Christopher Moriates, James D Harrison, Victoria Valencia, Michael Ong, Robin Clarke, Neil Steers, Ron D Hays, Clarence H Braddock, Robert Wachter
BACKGROUND: Organisational culture affects physician behaviours. Patient safety culture surveys have previously been used to drive care improvements, but no comparable survey of high-value care culture currently exists. We aimed to develop a High-Value Care Culture Survey (HVCCS) for use by healthcare leaders and training programmes to target future improvements in value-based care. METHODS: We conducted a two-phase national modified Delphi process among 28 physicians and nurse experts with diverse backgrounds...
October 26, 2016: BMJ Quality & Safety
https://www.readbyqxmd.com/read/27773630/distribution-and-sub-types-of-afferent-fibre-in-the-mouse-urinary-bladder
#11
M S Rahnama'i, B T Biallosterski, Ph E V Van Kerrebroeck, G A van Koeveringe, J I Gillespie, S G de Wachter
AIM: Increased afferent fibre activity contributes to pathological conditions such as the overactive bladder syndrome. Nerve fibres running near the urothelium are considered to be afferent as no efferent system has yet been described. The aim of this study was to identify sub-types of afferent nerve fibres in the mouse bladder wall based on morphological criteria and analyse regional differences. MATERIALS AND METHODS: 27 bladders of six month old C57BL/6 mice were removed and tissues were processed for immunohistochemistry...
October 20, 2016: Journal of Chemical Neuroanatomy
https://www.readbyqxmd.com/read/27760450/-pulmonary-hypertension-associated-with-left-heart-disease-recommendations-of-the-cologne-consensus-conference-2016
#12
S Rosenkranz, I M Lang, R Blindt, D Bonderman, L Bruch, G P Diller, R Felgendreher, C Gerges, W Hohenforst-Schmidt, S Holt, C Jung, I Kindermann, T Kramer, W M Kübler, V Mitrovic, A Riedel, A Rieth, A Schmeisser, R Wachter, J Weil, C Opitz
The 2015 European Guidelines on Diagnosis and Treatment of Pulmonary Hypertension are also valid for Germany. While the guidelines contain detailed recommendations regarding pulmonary arterial hypertension (PAH), they contain only a relatively short paragraph on other, much more common forms of PH such as PH due to left heart disease. Despite the lack of data, targeted PAH treatments are increasingly being used for PH associated with left heart disease. This development is of concern because of limited ressources and the need to base treatments on scientific evidence...
October 2016: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/27756729/rethinking-medical-ward-quality
#13
Samuel Pannick, Robert M Wachter, Charles Vincent, Nick Sevdalis
No abstract text is available yet for this article.
October 18, 2016: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/27737697/loss-of-cerebellar-neurons-in-the-progression-of-lentiviral-disease-effects-of-cns-permeant-antiretroviral-therapy
#14
Christian Wächter, Lee E Eiden, Nedye Naumann, Candan Depboylu, Eberhard Weihe
BACKGROUND: The majority of investigations on HIV-associated neurocognitive disorders (HAND) neglect the cerebellum in spite of emerging evidence for its role in higher cognitive functions and dysfunctions in common neurodegenerative diseases. METHODS: We systematically investigated the molecular and cellular responses of the cerebellum as contributors to lentiviral infection-induced neurodegeneration, in the simian immunodeficiency virus (SIV)-infected rhesus macaque model for HIV infection and HAND...
October 14, 2016: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/27721413/mechanistic-validation-of-a-clinical-lead-stapled-peptide-that-reactivates-p53-by-dual-hdm2-and-hdmx-targeting
#15
F Wachter, A M Morgan, M Godes, R Mourtada, G H Bird, L D Walensky
Hydrocarbon-stapled peptides that display key residues of the p53 transactivation domain have emerged as bona fide clinical candidates for reactivating the tumor suppression function of p53 in cancer by dual targeting of the negative regulators HDM2 and HDMX. A recent study questioned the mechanistic specificity of such stapled peptides based on interrogating their capacity to disrupt p53/HDM2 and p53/HDMX complexes in living cells using a new recombinase enhanced bimolecular luciferase complementation platform (ReBiL)...
October 10, 2016: Oncogene
https://www.readbyqxmd.com/read/27681896/in-silico-analysis-of-a-novel-plasmid-from-the-coral-pathogen-vibrio-coralliilyticus-reveals-two-potential-ecological-islands
#16
Jenny Wachter, Stuart A Hill
As virulence often correlates with the presence of plasmid replicons in several Vibrio spp., this study investigated whether non-chromosomal DNA could be found in the coral pathogen, Vibrio coralliilyticus BAA-450. A circular plasmid, 26,631 bp in size, was identified. DNA sequence analysis indicated that the plasmid contained 30 open reading frames, six tRNA genes, 12 inverted repeats, three direct repeats and presented no continuous sequence identity to other replicons within the database. Consequently, these findings indicate that this is a novel, previously unidentified, plasmid...
January 4, 2016: Microorganisms
https://www.readbyqxmd.com/read/27669533/neuroendocrine-tumor-of-the-pancreas-with-cystic-appearance-mimicking-a-progressive-intraductal-papillary-mucinous-neoplasm-pitfall-in-medical-imaging
#17
Francesco Vitali, Deike Strobel, Lukas Pfeifer, Marc Heinrich, David Wachter, Markus F Neurath, Dane Wildner
No abstract text is available yet for this article.
January 2016: Endoscopy
https://www.readbyqxmd.com/read/27662843/qtl-mapping-of-fusarium-head-blight-resistance-in-three-related-durum-wheat-populations
#18
Noemie Prat, Camille Guilbert, Ursa Prah, Elisabeth Wachter, Barbara Steiner, Thierry Langin, Olivier Robert, Hermann Buerstmayr
The QTL Fhb1 was successfully introgressed and validated in three durum wheat populations. The novel germplasm and the QTL detected will support improvement of Fusarium resistance in durum wheat. Durum wheat (Triticum durum Desf.) is particularly susceptible to Fusarium head blight (FHB) and breeding for resistance is hampered by limited genetic variation within this species. To date, resistant sources are mainly available in a few wild relative tetraploid wheat accessions. In this study, the effect of the well-known hexaploid wheat (Triticum aestivum L...
September 23, 2016: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
https://www.readbyqxmd.com/read/27659399/adrenergic-signaling-elements-in-the-bladder-wall-of-the-adult-rat
#19
Sara Persyn, Jane Eastham, Stefan De Wachter, James Gillespie
A growing body of work is describing the absence of a significant sympathetic innervation of the detrusor implying little sympathetic regulation of bladder contractility. However, low doses of adrenergic agonists are capable of relaxing the bladder smooth muscle. If these effects underpin a physiological response then the cellular nature and operation of this system are currently unknown. The present immunohistochemistry study was done to explore the existence of alternative adrenergic signaling elements in the rat bladder wall...
September 10, 2016: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/27638528/-new-prognostic-and-predictive-markers-for-breast-cancer
#20
D L Wachter
Breast cancer can be divided into four molecular subtypes with different prognoses using immunohistochemical markers in the routine clinicopathological work-up. The protein Ki-67 is of central importance in this context, in particular to distinguish between luminal A and luminal B carcinomas. Determination of the Ki-67 index of a carcinoma also allows a prediction of the likelihood of the response to chemotherapy. Additionally, the expression of certain cytokeratins in tumor cells is associated with a poor response to chemotherapy...
November 2016: Der Pathologe
keyword
keyword
58539
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"