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https://www.readbyqxmd.com/read/28110494/a-systematic-review-of-cognitive-effects-of-exercise-in-depression
#1
N Brondino, M Rocchetti, L Fusar-Poli, E Codrons, L Correale, M Vandoni, C Barbui, P Politi
OBJECTIVE: The aim of the present systematic review and meta-analysis was to evaluate the impact of physical exercise on cognitive symptoms in depressed adult patients. METHODS: Systematic literature search was performed in Web of Science™ and CINAHL from inception to August 2016. Two reviewers independently selected randomized trials evaluating the effect of exercise on cognitive functions in patients with a validated diagnosis of depression. Outcome measures included global cognition and different cognitive domains (speed of processing, attention/vigilance, working memory, verbal and visual memory, and reasoning)...
January 22, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28110475/pattern-recognition-of-spectral-entropy-features-for-detection-of-alcoholic-and-control-visual-erp-s-in-multichannel-eegs
#2
T K Padma Shri, N Sriraam
This paper presents a novel ranking method to select spectral entropy (SE) features that discriminate alcoholic and control visual event-related potentials (ERP'S) in gamma sub-band (30-55 Hz) derived from a 64-channel electroencephalogram (EEG) recording. The ranking is based on a t test statistic that rejects the null hypothesis that the group means of SE values in alcoholics and controls are identical. The SE features with high ranks are indicative of maximal separation between their group means. Various sizes of top ranked feature subsets are evaluated by applying principal component analysis (PCA) and k-nearest neighbor (k-NN) classification...
January 21, 2017: Brain Informatics
https://www.readbyqxmd.com/read/28110408/gingival-recessions-of-lower-incisors-after-proclination-by-orthodontics-alone-or-in-combination-with-anterior-mandibular-alveolar-process-distraction-osteogenesis
#3
Gregory S Antonarakis, Christof Urs Joss, Albino Triaca, Anne Marie Kuijpers-Jagtman, Stavros Kiliaridis
OBJECTIVES: The aim of this study was to longitudinally compare periodontal conditions in consecutive patients who had orthodontic treatment with proclination of lower incisors either by orthodontics alone or in combination with anterior mandibular alveolar process distraction osteogenesis (DO). MATERIALS AND METHODS: Nineteen patients had orthodontic treatment with DO, 18 with extraction of lower premolars (Ex), and 18 without extractions (Nonex). Lateral cephalograms were used to evaluate lower incisor proclination, while study casts and intraoral photographs were used to evaluate labial and lingual gingival recessions before (T1) and at an average of 4...
January 21, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28110310/impact-of-an-expanded-hospital-recognition-program-for-stroke-quality-of-care
#4
Paul A Heidenreich, Xin Zhao, Adrian F Hernandez, Lee H Schwamm, Eric Smith, Mat Reeves, Eric D Peterson, Gregg C Fonarow
BACKGROUND: In 2009, the Get With The Guidelines-Stroke (GWTG-Stroke) program offered additional recognition if hospitals performed well on certain stroke quality measures. We sought to determine whether quality of care for all hospitals participating in GWTG-Stroke improved with this expanded recognition program. METHODS AND RESULTS: We examined hospital-level performance on 6 quality of care (process) measures and 1 defect-free composite quality measure for stroke following expansion of the existing performance measure recognition program...
January 21, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28110256/ethical-experiential-learning-in-medical-nursing-and-allied-health-education-a-narrative-review
#5
REVIEW
Sandra Grace, Ev Innes, Narelle Patton, Lynette Stockhausen
: Students enrolled in medical, nursing and health science programs often participate in experiential learning in their practical classes. Experiential learning includes peer physical examination and peer-assisted learning where students practise clinical skills on each other. OBJECTIVES: To identify effective strategies that enable ethical experiential learning for health students during practical classes. DESIGN: A narrative review of the literature...
January 10, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/28110243/a-biomechanical-testing-system-to-determine-micromotion-between-hip-implant-and-femur-accounting-for-deformation-of-the-hip-implant-assessment-of-the-influence-of-rigid-body-assumptions-on-micromotions-measurements
#6
Steven Leuridan, Quentin Goossens, Jorg Roosen, Leonard Pastrav, Kathleen Denis, Michiel Mulier, Wim Desmet, Jos Vander Sloten
BACKGROUND: Accurate pre-clinical evaluation of the initial stability of new cementless hip stems using in vitro micromotion measurements is an important step in the design process to assess the new stem's potential. Several measuring systems, linear variable displacement transducer-based and other, require assuming bone or implant to be rigid to obtain micromotion values or to calculate derived quantities such as relative implant tilting. METHODS: An alternative linear variable displacement transducer-based measuring system not requiring a rigid body assumption was developed in this study...
January 16, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28110208/inflammatory-pathway-genes-associated-with-inter-individual-variability-in-the-trajectories-of-morning-and-evening-fatigue-in-patients-receiving-chemotherapy
#7
Fay Wright, Marilyn Hammer, Steven M Paul, Bradley E Aouizerat, Kord M Kober, Yvette P Conley, Bruce A Cooper, Laura B Dunn, Jon D Levine, Gail DEramo Melkus, Christine Miaskowski
Fatigue, a highly prevalent and distressing symptom during chemotherapy (CTX), demonstrates diurnal and interindividual variability in severity. Little is known about the associations between variations in genes involved in inflammatory processes and morning and evening fatigue severity during CTX. The purposes of this study, in a sample of oncology patients (N=543) with breast, gastrointestinal (GI), gynecological (GYN), or lung cancer who received two cycles of CTX, were to determine whether variations in genes involved in inflammatory processes were associated with inter-individual variability in initial levels as well as in the trajectories of morning and evening fatigue...
January 19, 2017: Cytokine
https://www.readbyqxmd.com/read/28110138/contributions-to-ultrasound-monitoring-of-the-process-of-milk-curdling
#8
Antonio Jiménez, Montaña Rufo, Jesús M Paniagua, Abel T Crespo, M Patricia Guerrero, M José Riballo
Ultrasound evaluation permits the state of milk being curdled to be determined quickly and cheaply, thus satisfying the demands faced by today's dairy product producers. This paper describes the non-invasive ultrasonic method of in situ monitoring the changing physical properties of milk during the renneting process. The basic objectives of the study were, on the one hand, to confirm the usefulness of conventional non-destructive ultrasonic testing (time-of-flight and attenuation of the ultrasound waves) in monitoring the process in the case of ewe's milk, and, on the other, to include other ultrasound parameters which have not previously been considered in studies on this topic, in particular, parameters provided by the Fast Fourier Transform technique...
January 10, 2017: Ultrasonics
https://www.readbyqxmd.com/read/28110115/application-of-an-ecosystem-model-to-evaluate-the-importance-of-different-processes-and-food-web-structure-for-transfer-of-13-elements-in-a-shallow-lake
#9
L Konovalenko, C Bradshaw, E Andersson, U Kautsky
In environmental risk assessments of nuclear waste, there is need to estimate the potential risks of a large number of radionuclides over a long time period during which the environment is likely to change. Usually concentration ratios (CRs) are used to calculate the activity concentrations in organisms. However, CRs are not available for all radionuclides and they are not easily scalable to the varying environment. Here, an ecosystem transport model of elements, which estimates concentrations in organisms using carbon flows and food transfer instead of CR is presented...
January 18, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/28110099/high-dietary-intake-of-specific-fatty-acids-increases-risk-of-flares-in-patients-with-ulcerative-colitis-in-remission-during-treatment-with-aminosalicylates
#10
Edward L Barnes, Molly Nestor, Louisa Onyewadume, Punyanganie De Silva, Joshua R Korzenik
BACKGROUND & AIMS: Dietary factors may have a significant role in relapse of disease among patients with ulcerative colitis (UC). However, the relationship between diet and UC is inadequately understood. We analyzed data from the diet's role in exacerbations of mesalamine maintenance study to determine whether dietary factors affect risk of disease flares in patients with UC. METHODS: We performed a prospective, multi-center, observational study of 412 patients, from 25 sites, with UC in remission during monotherapy with an aminosalicylate...
January 18, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28109965/a-novel-acidic-ph-fluorescent-probe-based-on-a-benzothiazole-derivative
#11
Qiujuan Ma, Xian Li, Suxiang Feng, Beibei Liang, Tiqiang Zhou, Min Xu, Zhuoyi Ma
A novel acidic pH fluorescent probe 1 based on a benzothiazole derivative has been designed, synthesized and developed. The linear response range covers the acidic pH range from 3.44 to 6.46, which is valuable for pH researches in acidic environment. The evaluated pKa value of the probe 1 is 4.23. The fluorescence enhancement of the studied probe 1 with an increase in hydrogen ions concentration is based on the hindering of enhanced photo-induced electron transfer (PET) process. Moreover, the pH sensor possesses a highly selective response to H(+) in the presence of metal ions, anions and other bioactive small molecules which would be interfere with its fluorescent pH response...
January 12, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28109951/a-cognitive-approach-for-design-of-a-multimedia-informed-consent-video-and-website-in-pediatric-research
#12
Holly Antal, H Timothy Bunnell, Suzanne M McCahan, Chris Pennington, Tim Wysocki, Kathryn Blake
OBJECTIVE: Poor participant comprehension of research procedures following the conventional face-to-face consent process for biomedical research is common. We describe the development of a multimedia informed consent video and website that incorporates cognitive strategies to enhance comprehension of study related material directed to parents and adolescents. MATERIALS AND METHODS: A multidisciplinary team was assembled for development of the video and website that included human subjects professionals; psychologist researchers; institutional video and web developers; bioinformaticians and programmers; and parent and adolescent stakeholders...
January 18, 2017: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/28109907/circadian-gene-variants-and-breast-cancer
#13
Edyta Reszka, Monika Przybek, Olav Muurlink, Beata Peplonska
The endogenous and self-sustained circadian rhythm generated and maintained in suprachiasmatic nucleus and peripheral tissues can coordinate various molecular, biochemical and physiological processes in living organisms resulting in the adaptation to environmental cues, e.g. light. Multifactorial breast cancer etiology also involves circadian gene alterations, especially among individuals exposed to light at night. Indeed, shift work that causes circadian disruption has been classified by the International Agency for Research on Cancer as a probable human carcinogen, group 2A...
January 18, 2017: Cancer Letters
https://www.readbyqxmd.com/read/28109811/production-and-characterization-of-bacterial-cellulose-membranes-with-hyaluronic-acid-from-chicken-comb
#14
Sabrina Alves de Oliveira, Bruno Campos da Silva, Izabel Cristina Riegel-Vidotti, Alexandre Urbano, Paula Cristina de Sousa Faria-Tischer, Cesar Augusto Tischer
The bacterial cellulose (BC), from Gluconacetobacter hansenii, is a biofilm with a high degree of crystallinity that can be used for therapeutic purposes and as a candidate for healing wounds. Hyaluronic acid (HA) is a constitutive polysaccharide found in the extracellular matrix and is a material used in tissue engineering and scaffolding for tissue regeneration. In this study, polymeric composites were produced in presence of hyaluronic acid isolated from chicken comb on different days of fermentation, specifically on the first (BCHA-SABT0) and third day (BCHA-SABT3) of fermentation...
January 18, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28109797/evaluation-of-sleep-bruxism-with-a-novel-designed-occlusal-splint
#15
Kentaro Hirai, Tomoko Ikawa, Yuko Shigeta, Shuji Shigemoto, Takumi Ogawa
PURPOSE: This report presents our evaluation system that assesses sleep bruxism. The characteristics and fabrication process of our novel designed splint, and the analysis process of our system are presented. METHODS: The subjects were 17 volunteers. The splint was fabricated with a self-curing resin compounded with an amino-acid powder for easy wear on the semi-adjustable articulator, and adjusted for a full-balanced occlusion. An impression of the splint, located on the cast, was taken before and after it was worn...
January 18, 2017: Journal of Prosthodontic Research
https://www.readbyqxmd.com/read/28109790/discovery-of-peptidic-mir-21-processing-inhibitor-by-mirror-image-phage-display-a-novel-method-to-generate-rna-binding-d-peptides
#16
Kotaro Sakamoto, Kentaro Otake, Tadashi Umemoto
A novel method to generate RNA binding D-peptide has been developed. To achieve the screening method, phage display was applied to "Mirrored" RNA (L-enantiomer of RNA). We have selected pre-miR21 as an initial screening target to demonstrate the method. The mirrored pre-miR-21 binding peptide sequences were successfully obtained, and were chemically synthesized using D-amino acids. D-peptide is expected to have favorable properties as a drug candidate such as protease resistance and low immunogenicity. As a result of binding evaluation of the D-peptide to pre-miR-21, the EC50 value was 440nM...
January 10, 2017: Bioorganic & Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/28109561/lithium-reverses-behavioral-and-axonal-transport-related-changes-associated-with-ank3-bipolar-disorder-gene-disruption
#17
Michael G Gottschalk, Melanie P Leussis, Tillmann Ruland, Klaudio Gjeluci, Tracey L Petryshen, Sabine Bahn
Ankyrin 3 (ANK3) has been implicated as a genetic risk factor for bipolar disorder (BD), however the resulting pathophysiological and treatment implications remain elusive. In a preclinical systems biological approach, we aimed to characterize the behavioral and proteomic effects of Ank3 haploinsufficiency and chronic mood-stabilizer treatment in mice. Psychiatric-related behavior was evaluated with the novelty-suppressed feeding (NSF) paradigm, elevated plus maze (EPM) and a passive avoidance task (PAT). Tandem mass spectrometry (MS(E)) was employed for hippocampal proteome profiling...
January 18, 2017: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28109506/rat-model-of-chronic-tympanic-membrane-perforation-a-longitudinal-histological-evaluation-of-underlying-mechanisms
#18
Allen Y Wang, Lawrence J Liew, Yi Shen, Jeffrey T Wang, Magnus von Unge, Marcus D Atlas, Rodney J Dilley
OBJECTIVE: To evaluate histologically the progressive development and underlying mechanisms of chronic tympanic membrane perforation (TMP) in a rat model using a two-weeks ventilation tube (VT) treatment combined with topical application of mitomycin C/dexamethasone (VT-M/D), compared with normal tympanic membrane and acute TMPs. METHODS: Fifty male Sprague-Dawley rats were divided into three experimental groups: a normal control group (n = 5), an acute TMP group (n = 5) (i...
February 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28109488/juvenile-systemic-lupus-erythematosus-jsle-auditory-pathway-affection-in-relation-to-disease-activity
#19
M A Kotait, H H Abd Elnabi, T A Gabr
BACKGROUND: Juvenile Systemic lupus erythematosus (jSLE) is an autoimmune disease with the potential to affect a variety of organs in children or adolescents. jSLE is characterized by its severity and more widespread organ involvement specially central nervous system. OBJECTIVES: To evaluate auditory processing and cognitive functions in children and adolescents with SLE taking into consideration the disease severity. METHODS: This work included 40 normal hearing pediatric patients diagnosed as SLE (23 with active disease and 17 with inactive disease) and a control group included 30 matched healthy children...
February 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28109439/deep-profiling-of-proteome-and-phosphoproteome-by-isobaric-labeling-extensive-liquid-chromatography-and-mass-spectrometry
#20
B Bai, H Tan, V R Pagala, A A High, V P Ichhaporia, L Hendershot, J Peng
Mass spectrometry-based proteomics has experienced an unprecedented advance in comprehensive analysis of proteins and posttranslational modifications, with particular technical progress in liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) and isobaric labeling multiplexing capacity. Here, we introduce a deep proteomics profiling protocol that combines 10-plex tandem mass tag (TMT) labeling with an optimized LC-MS/MS platform to quantitate whole proteome and phosphoproteome. The major steps include protein extraction and digestion, TMT labeling, two-dimensional liquid chromatography, TiO2-mediated phosphopeptide enrichment, high-resolution mass spectrometry, and computational data processing...
2017: Methods in Enzymology
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