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Common bile duct exploration

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https://www.readbyqxmd.com/read/29438852/transcriptome-analysis-to-assess-the-cholestatic-hepatotoxicity-induced-by-polygoni-multiflori-radix-up-regulation-of-key-enzymes-of-cholesterol-and-bile-acid-biosynthesis
#1
Li-Long Jiang, Dong-Sheng Zhao, Ya-Xi Fan, Qiong Yu, Yi-Sheng Lai, Ping Li, Hui-Jun Li
Polygoni Multiflori Radix (PMR) has been commonly used as a tonic in China for centuries. However, PMR-associated hepatotoxicity is becoming a safety issue. Cholestasis often occurs in PMR-induced hepatotoxicity in clinical medicine, but the exact mechanism is not completely understood. An RNA-Seq method was employed, in the present study, to explore the molecular mechanism of cholestatic liver injury induced by PMR, characterized by the hepatic transcriptional response in rats exposed to 1 and 20 g/kg PMR for 90 days...
February 10, 2018: Journal of Proteomics
https://www.readbyqxmd.com/read/29362661/laparoscopy-assisted-micropercutaneous-choledocholithotripsy-with-holmium-laser-in-a-cholecystectomized-patient-an-initial-report
#2
Kaan Gökçen, Mustafa Atabey, Pınar Gökçen, Gökhan Gökçe
We present a novel minimally invasive technique, laparoscopy-assisted micropercutaneous choledocholithotripsy, for choledocholithiasis that cannot be treated with other endoscopic techniques. This technique includes standard laparoscopic exploration of the common bile duct, combined with an all-seeing needle and holmium laser lithotripsy. As is known, an all-seeing needle is used in micropercutaneous nephrolithotomy for middle-sized renal stones. In this technique, an all-seeing needle was inserted into the dilatated common bile duct under laparoscopic vision and then a lithotripsy procedure was performed with a holmium laser behind the biliary stent...
December 2017: Wideochirurgia i Inne Techniki Mało Inwazyjne, Videosurgery and Other Miniinvasive Techniques
https://www.readbyqxmd.com/read/29345755/expression-of-hepatic-progenitor-cell-markers-in-acute-cellular-rejection-of-liver-allografts-an-immunohistochemical-study
#3
Regina Cheuk-Lam Lo, Kristy Kwan-Shuen Chan, Carmen Oi-Ning Leung, Irene Oi-Lin Ng
BACKGROUND: Hepatic progenitor cells (HPC) are induced following liver injury to facilitate regeneration. Acute cellular rejection (ACR) is a common complication after liver transplantation as a result of immune-mediated liver injury. In this study, we characterized HPC phenotype in liver allograft biopsy with ACR. We also explored the correlation between expression HPC immunophenotype and clinicopathological parameters. METHODS: Forty-four liver allograft biopsies performed between 2008 and 2016 in a single center with histologically proven ACR were examined for immunohistochemical expression of HPC markers CK19 and Sox9...
January 18, 2018: Clinical Transplantation
https://www.readbyqxmd.com/read/29336751/laparoscopic-exploration-can-salvage-recurrent-common-bile-duct-stone-after-cholecystectomy
#4
Wen-Song Liu, Yan Zou, Bo Yang, Yong Jiang, Dong-Lin Sun
Conventionally, patients suffered from recurrent common bile duct (CBD) stone after cholecystectomy are suggested to be treated with endoscopic retrograde cholangiopancreaticography. This study was designed to explore the feasibility of laparoscopic common bile duct exploration (LCBDE) as a salvage procedure for recurrent CBD calculi after cholecystectomy. A retrospective review was conducted of data from 65 patients who underwent LCBDE for recurrent CBD calculi after cholecystectomy from January 2011 to July 2015...
December 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/29336749/heroic-measures-for-an-american-hero-attempting-to-save-the-life-of-general-douglas-macarthur
#5
Theodore N Pappas
General Douglas MacArthur was a towering public figure on an international stage for the first half of the 20th century. He was healthy throughout his life but developed a series of medical problems when he entered his 80s. This article reviews the General's medical care during two separate life-threatening medical crises that required surgical intervention. The first episode occurred in 1960 when MacArthur presented with renal failure due to an obstructed prostate. Four years later after his 84th birthday, MacArthur developed bile duct obstruction from common duct stones...
December 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/29273878/laparoscopic-common-bile-duct-exploration
#6
Marc Zerey, Stephen Haggerty, William Richardson, Byron Santos, Robert Fanelli, L Michael Brunt, Dimitrios Stefanidis
No abstract text is available yet for this article.
December 22, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29245291/delayed-diagnosis-of-abdominal-pain-in-patient-with-situs-inversus-totalis-in-emergency-department-a-case-report
#7
Ying Liu, Lile Wu, Yanhong Chen, Dongze Li, Jun Jiang, Wu Zhong, Yu Cao
RATIONALE: Abdominal pain is one of the most common complaints for patients in emergency department. It's difficult to make an accurate diagnosis by emergency physician in time, especially in patients with situs inversus totalis. PATIENT CONCERNS: A patient with acute exacerbation of chronic left upper quadrant abdominal pain.DIAGNOSES:: cholangiolithiasis with situs inversus totalis. INTERVENTIONS: laparoscopic cholecystectomy and laparoscopic exploration of common bile duct...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29191675/single-stage-laparoscopic-management-of-choledocholithiasis-an-analysis-after-implementation-of-a-mastery-learning-resident-curriculum
#8
Ben Schwab, Ezra N Teitelbaum, Jeffrey H Barsuk, Nathaniel J Soper, Eric S Hungness
BACKGROUND: Laparoscopic common bile duct exploration is an underutilized treatment for choledocholithiasis. We sought to evaluate the impact of a simulation-based mastery-learning curriculum for surgical residents on laparoscopic common bile duct exploration utilization and to compare outcomes for patients treated with laparoscopic common bile duct exploration versus endoscopic retrograde cholangiopancreatography (ERCP). METHODS: The number of laparoscopic common bile duct explorations performed before and after curriculum implementation was reviewed and outcomes were compared between patients with choledocholithiasis managed with laparoscopic common bile duct exploration and endoscopic retrograde cholangiopancreatography...
November 27, 2017: Surgery
https://www.readbyqxmd.com/read/29137249/endoscopic-retrograde-cholangiopancreatography-versus-laparoscopic-exploration-for-common-bile-duct-stones-in-post-cholecystectomy-patients-a-retrospective-study
#9
Xiaohong Wang, Chenguang Dai, Zhonghua Jiang, Lili Zhao, Min Wang, Limei Ma, Xueming Tan, Li Liu, Xiang Wang, Zhining Fan
Background and Objective: Common bile duct (CBD) stones are common in patients even after cholecystectomy. Besides endoscopic retrograde cholangiography (ERCP), laparoscopic common bile duct exploration (LCBDE) is also applied. This study aims to compare clinical indications, therapeutic benefits and complications for these two managements. Methods: From October 2012 to February 2015, 1072 consecutive patients were diagnosed as choledocholithiasis in our single hospital...
October 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/29133895/the-safety-and-feasibility-of-laparoscopic-common-bile-duct-exploration-for-treatment-patients-with-previous-abdominal-surgery
#10
Yong Huang, Qian Feng, Kai Wang, Xiaoli Xiong, Shubing Zou
The purpose of this study was to evaluate the safety and feasibility of laparoscopic common bile duct exploration (LCBDE) in patients with previous abdominal surgery (PAS). The outcomes were compared in 139 patients (103 upper and 36 lower abdominal surgeries) with PAS and 361 without PAS who underwent LCBDE. The operative time, hospital stay, rate of open conversion, postoperative complications, duct clearance, and blood loss were compared. Patients with PAS had longer operative times (P = 0.006), higher hospital costs (P = 0...
November 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29100711/a-predictive-nomogram-to-identify-factors-influencing-the-success-of-a-concomitant-laparoscopic-cholecystectomy-with-common-bile-duct-exploration-for-choledocholithiasis
#11
Koy Min Chue, Jun Wei Bryan Aw, Sin Hui Melissa Chua, Zhaojin Chen, Shridhar Ganpathi Iyer, Krishnakumar Madhavan, Alfred Wei Chieh Kow
BACKGROUND: Single-staged laparoscopic common bile duct exploration (LCBDE) offers clear benefits in terms of cost and shorter hospitalization stays. However, a failed LCBDE requiring conversion to open surgery is associated with increased morbidity. This study reviewed the factors determining success of LCBDE, and created a predictive nomogram to stratify patients for the procedure. METHODS: A retrospective analysis of 109 patients who underwent LCBDE was performed...
October 31, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29062580/hem-o-lok-clips-migration-an-easily-neglected-complication-after-laparoscopic-biliary-surgery
#12
Jun-Wen Qu, Gui-Yang Wang, Zhi-Qing Yuan, Ke-Wei Li
Clip migration into the common bile duct (CBD) is a rare but well-established phenomenon of laparoscopic biliary surgery. The mechanism and exact incidence of clip migration are both poorly understood. Clip migration into the common bile duct can cause recurrent cholangitis and serve as a nidus for stone formation. We present a case, a 54-year-old woman, of clip-induced cholangitis resulting from surgical clip migration 12 months after laparoscopic cholecystectomy and laparoscopic common bile duct exploration (LC+LCBDE) with primary closure...
2017: Case Reports in Surgery
https://www.readbyqxmd.com/read/29054446/laparoscopic-common-bile-duct-exploration-versus-endoscopic-retrograde-cholangiopancreatography-for-choledocholithiasis-found-at-time-of-laparoscopic-cholecystectomy-analysis-of-a-large-integrated-health-care-system-database
#13
Mohammed H Al-Temimi, Edwin G Kim, Bindupriya Chandrasekaran, Vanessa Franz, Charles N Trujillo, Asrai Mousa, Deron J Tessier, Samir D Johna, David A Santos
No abstract text is available yet for this article.
October 5, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/29046958/laparoscopic-choledochoduodenostomy-as-a-reliable-rescue-procedure-for-complicated-bile-duct-stones
#14
Palanisamy Senthilnathan, Dhawal Sharma, Sandeep C Sabnis, S Srivatsan Gurumurthy, E Senthil Anand, V P Nalankilli, Natesan Anand Vijai, Palanivelu Praveen Raj, Ramakrishnan Parthasarathy, Subbaiah Rajapandian, Chinnusamy Palanivelu
BACKGROUND: Endoscopic retrograde cholangiopancreatography (ERCP) with stone extraction is generally accepted as first line management for common bile duct (CBD) stones. CBD exploration, either by open or laparoscopic approach nowadays, is usually reserved for ERCP failures, complicated stone locations, along with altered anatomical situations. The aim of this study was to highlight the increasing role of laparoscopic choledochoduodenostomy which is not only a reliable but also as a rescue procedure for those failed ERCP cases due to complicated bile duct stones...
October 18, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29031685/comparison-of-the-composition-of-bile-acids-in-bile-of-patients-with-adenocarcinoma-of-the-pancreas-and-benign-disease
#15
COMPARATIVE STUDY
David O Rees, Peter J Crick, Gareth J Jenkins, Yuqin Wang, William J Griffiths, Tim H Brown, Bilal Al-Sarireh
Bile acids have been implicated in the development of gastrointestinal malignancies. Both the specific nature of individual bile acids and their concentration appear key factors in the carcinogenic potency of bile. Using liquid chromatography mass spectrometry (LC-MS) we performed quantitative profiling of bile extracted directly from the common bile duct in 30 patients (15 patients with pancreatic cancer and 15 patients with benign disease). Separation and detection of bile acids was performed using a 1.7μm particle size reversed-phase C18 LC column at a flow rate of 200μL/min with negative electrospray ionization MS...
November 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29023332/should-t-tube-drainage-be-performed-for-choledocholithiasis-after-laparoscopic-common-bile-duct-exploration-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#16
Woods Zhang, Ge Li, Yan-Ling Chen
BACKGROUND: Laparoscopic common bile duct exploration (LCBDE) has been verified to be a comparatively effective treatment approach for uncomplicated choledocholithiasis, and it has been previously proposed that the primary duct closure (PDC) technique, in which the bile duct can directly be sutured in only 1 step compared with the T-tube drainage (TTD), can be deemed a choice after LCBDE; however, the conventional TTD performance is controversial in the minimally invasive surgery era...
October 11, 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/28989998/mirizzi-syndrome-necessity-for-safe-approach-in-dealing-with-diagnostic-and-treatment-challenges
#17
Bader Hamza Shirah, Hamza Asaad Shirah, Khalid B Albeladi
BACKGROUNDS/AIMS: The challenging dilemma of Mirizzi syndrome for operating surgeons arises from the difficulty to diagnose it preoperatively, and approximately 50% of cases are diagnosed intraoperatively. In this study, we analysed the effectiveness of diagnostic modalities and treatment options in our series of Mirizzi syndrome. METHODS: Patients had a preoperative or intraoperative diagnosis of Mirizzi syndrome, and were classified into three groups: Group 1: Incidental finding of Mirizzi syndrome intraoperatively (n=34)...
August 2017: Annals of Hepato-Biliary-Pancreatic Surgery
https://www.readbyqxmd.com/read/28976804/comparative-study-of-three-bile-duct-closure-methods-following-laparoscopic-common-bile-duct-exploration-for-choledocholithiasis
#18
Pablo Parra-Membrives, Darío Martínez-Baena, José Lorente-Herce, Granada Jiménez-Riera
BACKGROUND: There are three choledochotomy closure methods available following laparoscopic common bile duct exploration: T-tube insertion, antegrade stenting, and primary choledochorrhaphy. We reviewed the experience of 12 years at our center searching for the optimal closure technique. METHODS: We analyzed retrospectively 146 patients that underwent one of the three closure methods from February 2004 to March 2016. Hospital stay, need for readmission, incidence of early and long-term complications, and biliary leakage development and their clinical impact were determined for each technique...
October 4, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28948425/endoscopic-therapy-of-biliary-injury-after-cholecystectomy
#19
Mia Rainio, Outi Lindström, Marianne Udd, Carola Haapamäki, Arno Nordin, Leena Kylänpää
BACKGROUND: Iatrogenic bile duct injury (BDI) is a common complication after cholecystectomy. Patients are mainly treated endoscopically, but the optimal treatment method has remained unclear. AIMS: The aim was to analyze endoscopic treatment in BDI after cholecystectomy and to explore endoscopic sphincterotomy (ES), with or without stenting, as the primary treatment for an Amsterdam type A bile leak. METHODS: All patients referred to Helsinki University Hospital endoscopy unit due to a suspected BDI between the years 2004 and 2014 were included in this retrospective study...
September 25, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28939251/laparoscopic-common-bile-duct-exploration-versus-endoscopic-retrograde-cholangiopancreatography-for-choledocholithiasis-found-at-time-of-laparoscopic-cholecystectomy-analysis-of-a-large-integrated-health-care-system-database
#20
COMPARATIVE STUDY
Mohammed H Al-Temimi, Edwin G Kim, Bindupriya Chandrasekaran, Vanessa Franz, Charles N Trujillo, Asrai Mousa, Deron J Tessier, Samir D Johna, David A Santos
BACKGROUND: We compared endoscopic retrograde cholangiopancreatography (ERCP) and laparoscopic common bile duct exploration (LCBDE) for managing choledocholithiasis found at time of cholecystectomy. METHODS: One hundred and five LCBDE (2005-2015) were compared to 195 LC/ERCP (2014-2015) from the Southern California Kaiser Permanente database. RESULTS: LC/ERCP was more effective at clearing the CBD (98% vs. 88.6%, p = 0.01); but required more procedures per patient (mean ± standard deviation, 1...
December 2017: American Journal of Surgery
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