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https://www.readbyqxmd.com/read/28640865/association-between-suicide-related-ideations-and-affective-temperaments-in-the-japanese-general-adult-population
#1
Nobuyuki Mitsui, Yukiei Nakai, Takeshi Inoue, Niki Udo, Kan Kitagawa, Yumi Wakatsuki, Rie Kameyama, Atsuhito Toyomaki, Yoichi M Ito, Yuji Kitaichi, Shin Nakagawa, Ichiro Kusumi
BACKGROUND: Suicide rates are vastly higher in Japan than in many other countries, although the associations between affective temperaments and suicide-related ideations in the general adult population remain unclear. Therefore, we aimed to elucidate these associations in the present study. METHODS: We analyzed data from 638 Japanese volunteers who completed both the Patient Health Questionnaire (PHQ-9) and the Temperament Evaluation of the Memphis, Pisa, Paris, and San Diego Auto-questionnaire (TEMPS-A)...
2017: PloS One
https://www.readbyqxmd.com/read/28635149/underuse-of-risk-assessment-and-overuse-of-ctpa-in-patients-with-suspected-pulmonary-thromboembolism
#2
Michael Perera, Leena Aggarwal, Ian A Scott, Nicholas Cocks
INTRODUCTION: Evidence suggests potential overuse of computerised tomography pulmonary angiography (CTPA) in patients with suspected pulmonary thromboembolism (PTE) in the absence of consistent use of pre-test clinical prediction rules and D-dimer assays. METHODS: 344 consecutive patients undergoing CTPA at a tertiary hospital were studied for use of D-dimer assays and clinical prediction rules for PTE. For each patient, a modified Wells score (mWS), revised Geneva score (rGS) and PISA model were calculated retrospectively; performance characteristics for each rule for PTE were determined in reference to results of CTPA...
June 21, 2017: Internal Medicine Journal
https://www.readbyqxmd.com/read/28634872/predictive-markers-of-response-to-everolimus-and-sunitinib-in-neuroendocrine-tumors
#3
Diana Martins, Francesca Spada, Ioana Lambrescu, Manila Rubino, Chiara Cella, Bianca Gibelli, Chiara Grana, Dario Ribero, Emilio Bertani, Davide Ravizza, Guido Bonomo, Luigi Funicelli, Eleonora Pisa, Dario Zerini, Nicola Fazio
Neuroendocrine tumors (NETs) represent a large and heterogeneous group of malignancies with various biological and clinical characteristics, depending on the site of origin and the grade of tumor proliferation. In NETs, as in other cancer types, molecularly targeted therapies have radically changed the therapeutic landscape. Recently two targeted agents, the mammalian target of rapamycin inhibitor everolimus and the tyrosine kinase inhibitor sunitinib, have both demonstrated significantly prolonged progression free survival in patients with advanced pancreatic NETs...
June 21, 2017: Targeted Oncology
https://www.readbyqxmd.com/read/28629424/evaluation-of-the-international-standardized-24-h-dietary-recall-methodology-globodiet-for-potential-application-in-research-and-surveillance-within-african-settings
#4
Elom Kouassivi Aglago, Edwige Landais, Geneviève Nicolas, Barrie Margetts, Catherine Leclercq, Pauline Allemand, Olaide Aderibigbe, Victoire Damienne Agueh, Paul Amuna, George Amponsah Annor, Jalila El Ati, Jennifer Coates, Brooke Colaiezzi, Ella Compaore, Hélène Delisle, Mieke Faber, Robert Fungo, Inocent Gouado, Asmaa El Hamdouchi, Waliou Amoussa Hounkpatin, Amoin Georgette Konan, Saloua Labzizi, James Ledo, Carol Mahachi, Segametsi Ditshebo Maruapula, Nonsikelelo Mathe, Muniirah Mbabazi, Mandy Wilja Mirembe, Carmelle Mizéhoun-Adissoda, Clement Diby Nzi, Pedro Terrence Pisa, Karima El Rhazi, Francis Zotor, Nadia Slimani
BACKGROUND: Collection of reliable and comparable individual food consumption data is of primary importance to better understand, control and monitor malnutrition and its related comorbidities in low- and middle-income countries (LMICs), including in Africa. The lack of standardised dietary tools and their related research support infrastructure remains a major obstacle to implement concerted and region-specific research and action plans worldwide. Citing the magnitude and importance of this challenge, the International Agency for Research on Cancer (IARC/WHO) launched the "Global Nutrition Surveillance initiative" to pilot test the use of a standardized 24-h dietary recall research tool (GloboDiet), validated in Europe, in other regions...
June 19, 2017: Globalization and Health
https://www.readbyqxmd.com/read/28626247/time-resolved-saxs-studies-of-the-kinetics-of-thermally-triggered-release-of-encapsulated-silica-nanoparticles-from-block-copolymer-vesicles
#5
Charlotte J Mable, Matthew J Derry, Kate L Thompson, Lee A Fielding, Oleksandr O Mykhaylyk, Steven P Armes
Silica-loaded poly(glycerol monomethacrylate)-poly(2-hydroxypropyl methacrylate) diblock copolymer vesicles are prepared in the form of concentrated aqueous dispersions via polymerization-induced self-assembly (PISA). As the concentration of silica nanoparticles present during the PISA synthesis is increased up to 35% w/w, higher degrees of encapsulation of this component within the vesicles can be achieved. After centrifugal purification to remove excess non-encapsulated silica nanoparticles, SAXS, DCP, and TGA analysis indicates encapsulation of up to hundreds of silica nanoparticles per vesicle...
June 13, 2017: Macromolecules
https://www.readbyqxmd.com/read/28623760/gait-dynamics-in-pisa-syndrome-and-camptocormia-the-role-of-stride-length-and-hip-kinematics
#6
C Tramonti, S Di Martino, E Unti, D Frosini, U Bonuccelli, B Rossi, R Ceravolo, C Chisari
This is an observational cross-sectional study evaluating gait dynamics in patients with Parkinson's Disease (PD) and severe postural deformities, PD without axial deviations and healthy subjects. Ten PS individuals with Pisa syndrome (PS) and nine subjects with Camptocormia (CC) performed 3-D Gait Analysis and were evaluated with walking and balance scales. Correlations with clinical and functional scales were investigated. Spatio-temporal and kinematic data were compared to ten PD subjects without postural deformities (PP) and ten healthy matched individuals (CG)...
June 10, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28615770/the-mood-spectrum-and-temperamental-instability-in-unipolar-and-bipolar-disorder
#7
Manish Kumar, Pradeep Kumar Saha, Anwesha Mondal
BACKGROUND: The current categorical split of mood disorders in bipolar (BP) disorders and depressive disorders has recently been questioned. The presence of a significant number of manic/hypomanic symptoms in patients with recurrent unipolar depression seems to challenge the traditional dichotomy of unipolar-BP disorder. Two highly unstable personality features, i.e., the cyclothymic temperament (CT) and borderline personality disorder, have been found to be more common in BP disorder than in major depressive disorder...
May 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/28594245/chronotype-correlates-with-developmental-index-intelligence-and-academic-achievement-a-study-based-on-nationwide-indicators
#8
Christoph Randler
Chronotype or morningness-eveningness (M/E) is an individual trait with a biological basis. In this study, I analysed the relationship between M/E and nationwide available data, such as economic variables, school achievement, intelligence and conscientiousness, which is a personality trait. These variables have been chosen because, first, they are linked on the individual level with circadian preference, and, second these associations have been found based on meta-analyses, which gives these findings a high plausibility...
June 8, 2017: Chronobiology International
https://www.readbyqxmd.com/read/28579820/cannabis-and-intractable-chronic-pain-an-explorative-retrospective-analysis-of-italian-cohort-of-614-patients
#9
Guido Fanelli, Giuliano De Carolis, Claudio Leonardi, Adele Longobardi, Ennio Sarli, Massimo Allegri, Michael E Schatman
BACKGROUND: Despite growing interest in the therapeutic use of cannabis to manage chronic pain, only limited data that address these issues are available. In recent years, a number of nations have introduced specific laws to allow patients to use cannabis preparations to treat a variety of medical conditions. In 2015, the Italian government authorized the use of cannabis to treat several diseases, including chronic pain generally, spasticity in multiple sclerosis, cachexia and anorexia among AIDS and cancer patients, glaucoma, Tourette syndrome, and certain types of epilepsy...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28571268/comparison-of-serum-levels-of-endothelin-1-in-chronic-periodontitis-patients-before-and-after-treatment
#10
Waleed Khalid, Sheeja S Varghese, M Sankari, N D Jayakumar
INTRODUCTION: Endothelin-1 (ET-1) is a potent vasoconstrictive peptide with multi functional activity in various systemic diseases. Previous studies indicate the detection of ET-1 in gingival tissues and gingival crevicular fluid. AIM: The aim of this study was to estimate the serum ET-1 levels in clinically healthy subjects and subjects with chronic periodontitis, before and after treatment, and correlate it with the clinical parameters. MATERIALS AND METHODS: A total of 44 patients were included in the study...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28567260/cross-linked-cationic-diblock-copolymer-worms-are-superflocculants-for-micrometer-sized-silica-particles
#11
Nicholas J W Penfold, Yin Ning, Pierre Verstraete, Johan Smets, Steven P Armes
A series of linear cationic diblock copolymer nanoparticles are prepared by polymerization-induced self-assembly (PISA) via reversible addition-fragmentation chain transfer (RAFT) aqueous dispersion polymerization of 2-hydroxypropyl methacrylate (HPMA) using a binary mixture of non-ionic and cationic macromolecular RAFT agents, namely poly(ethylene oxide) (PEO113, Mn = 4400 g mol(-1); Mw/Mn = 1.08) and poly([2-(methacryloyloxy)ethyl]trimethylammonium chloride) (PQDMA125, Mn = 31 800 g mol(-1), Mw/Mn = 1.19)...
December 1, 2016: Chemical Science
https://www.readbyqxmd.com/read/28564492/photoinitiated-polymerization-induced-self-assembly-of-glycidyl-methacrylate-for-the-synthesis-of-epoxy-functionalized-block-copolymer-nano-objects
#12
Jianbo Tan, Dongdong Liu, Chundong Huang, Xueliang Li, Jun He, Qin Xu, Li Zhang
Herein, a novel photoinitiated polymerization-induced self-assembly formulation via photoinitiated reversible addition-fragmentation chain transfer dispersion polymerization of glycidyl methacrylate (PGMA) in ethanol-water at room temperature is reported. It is demonstrated that conducting polymerization-induced self-assembly (PISA) at low temperatures is crucial for obtaining colloidal stable PGMA-based diblock copolymer nano-objects. Good control is maintained during the photo-PISA process with a high rate of polymerization...
May 31, 2017: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/28525822/the-interplay-between-diabetes-depression-and-affective-temperaments-a-structural-equation-model
#13
Martino Belvederi Murri, Sara Mamberto, Lucia Briatore, Chiara Mazzucchelli, Mario Amore, Renzo Cordera
BACKGROUND: Diabetes and depression are reciprocally linked, but few studies modeled their interplay considering the influence of affective temperaments (AT) and demographic factors. METHODS: Participants with type 1 and type 2 diabetes (T1DM and T2DM, n=279) recruited from Diabetes Units were assessed with the Beck Depression Inventory (BDI), Temperament Evaluation of Memphis, Pisa, Paris and San Diego-autoquestionnaire version (TEMPS-A), Morisky Medication Adherence Scale (MMAS), Diabetes Distress Scale (DDS) and Cumulative Illness Rating Scales (CIRS)...
May 11, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28522980/acculturation-and-school-adjustment-of-immigrant-youth-in-six-european-countries-findings-from-the-programme-for-international-student-assessment-pisa
#14
Maja K Schachner, Jia He, Boris Heizmann, Fons J R Van de Vijver
School adjustment determines long-term adjustment in society. Yet, immigrant youth do better in some countries than in others. Drawing on acculturation research (Berry, 1997; Ward, 2001) and self-determination theory (Ryan and Deci, 2000), we investigated indirect effects of adolescent immigrants' acculturation orientations on school adjustment (school-related attitudes, truancy, and mathematics achievement) through school belonging. Analyses were based on data from the Programme for International Student Assessment from six European countries, which were combined into three clusters based on their migrant integration and multicultural policies: Those with the most supportive policies (Belgium and Finland), those with moderately supportive policies (Italy and Portugal), and those with the most unsupportive policies (Denmark and Slovenia)...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28517046/three-dimensional-proximal-flow-convergence-automatic-calculation-for-determining-mitral-valve-area-in-rheumatic-mitral-stenosis
#15
Francisco Sampaio, Ricardo Ladeiras-Lopes, João Almeida, Paulo Fonseca, Ricardo Fontes-Carvalho, José Ribeiro, Vasco Gama
PURPOSE: Management of patients with mitral stenosis (MS) depends heavily on the accurate quantification of mitral valve area (MVA) using echocardiography. All currently used two-dimensional (2D) methods have limitations. Estimation of MVA using the proximal isovelocity surface area (PISA) method with real time three-dimensional (3D) echocardiography may circumvent those limitations. We aimed to evaluate the accuracy of 3D direct measurement of PISA in the estimation of MVA. METHODS: Twenty-seven consecutive patients (median age of 63 years; 77...
May 18, 2017: Echocardiography
https://www.readbyqxmd.com/read/28505999/efficacy-of-a-combined-therapeutic-approach-in-the-management-of-pisa-syndrome
#16
Siria Di Martino, Elisa Unti, Caterina Tramonti, Sonia Mazzucchi, Ubaldo Bonuccelli, Bruno Rossi, Roberto Ceravolo, Carmelo Chisari
BACKGROUND: Pisa syndrome (PS) represents an important source of disability in Parkinson's disease (PD). Currently no consensus has been reached on its definition or diagnostic criteria, and therapeutic approaches are unspecific and often futile. Recently the role of abdominal muscles, and in particular of the external oblique (EO), in the pathogenesis of PS was hypothesized. OBJECTIVES: To evaluate the role of EO and propose a combined therapeutic approach in the management of PS...
May 11, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28502642/molecular-detection-of-tick-borne-pathogens-in-wild-red-foxes-vulpes-vulpes-from-central-italy
#17
Valentina Virginia Ebani, Guido Rocchigiani, Simona Nardoni, Fabrizio Bertelloni, Violetta Vasta, Roberto Amerigo Papini, Ranieri Verin, Alessandro Poli, Francesca Mancianti
Spleen samples from 153 red foxes, shot during regular hunting season in the province of Pisa (Central Italy), were examined to detect DNA of Anaplasma phagocytophilum, Ehrlichia canis, Coxiella burnetii, Francisella tularensis, Hepatozoon canis and Babesia sp./Theileria sp. DNA of vector-borne pathogens was detected in 120 (78.43%; 95% CI: 71.06-84.66%) foxes. Specifically, 75 (49%; 95% CI: 40.86-57.22%) animals scored PCR-positive per H. canis, 68 (44.44%; 95% CI: 36.42-52.69%) for E. canis, 35 (22.88%; 95% CI: 16...
May 11, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28497960/using-dynamic-covalent-chemistry-to-drive-morphological-transitions-controlled-release-of-encapsulated-nanoparticles-from-block-copolymer-vesicles
#18
Renhua Deng, Matthew J Derry, Charlotte J Mable, Yin Ning, Steven P Armes
Dynamic covalent chemistry is exploited to drive morphological order-order transitions to achieve the controlled release of a model payload (e.g., silica nanoparticles) encapsulated within block copolymer vesicles. More specifically, poly(glycerol monomethacrylate)-poly(2-hydroxypropyl methacrylate) (PGMA-PHPMA) diblock copolymer vesicles were prepared via aqueous polymerization-induced self-assembly in either the presence or absence of silica nanoparticles. Addition of 3-aminophenylboronic acid (APBA) to such vesicles results in specific binding of this reagent to some of the pendent cis-diol groups on the hydrophilic PGMA chains to form phenylboronate ester bonds in mildly alkaline aqueous solution (pH ∼ 10)...
June 7, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28497887/surviving-moment-to-moment-the-experience-of-living-in-a-state-of-ambivalence-for-those-with-recurrent-suicide-attempts
#19
Yvonne Bergmans, Evelyn Gordon, Rahel Eynan
OBJECTIVE: This qualitative study aimed to capture the experience of living in the ambivalent space between life and death for adults with recurrent suicide attempts (RSA). It sought to expand upon an earlier study that explored the processes involved in transitioning away from RSA among adults, which revealed that occupying this ambivalent space is a crucial part of this process. DESIGN: Interpretive phenomenological analysis (IPA) was used. This methodology was designed to explore the lived experiences and meaning making and enabled interpretation of the multidimensional subjective experiences of RSA participants...
May 12, 2017: Psychology and Psychotherapy
https://www.readbyqxmd.com/read/28496418/toward-the-identification-of-a-specific-psychopathology-of-substance-use-disorders
#20
REVIEW
Angelo G I Maremmani, Pier Paolo Pani, Luca Rovai, Silvia Bacciardi, Icro Maremmani
Addiction is a mental illness in which psychiatric conditions imply a prominent burden. Psychopathological symptoms in substance use disorder (SUD) patients are usually viewed as being assignable to the sphere of a personality trait or of comorbidity, leaving doubts about the presence of a specific psychopathology that could only be related to the toxicomanic process. Our research group at the University of Pisa has shed light on the possible definition of a specific psychopathological dimension in SUDs. In heroin use disorder patients, performing an exploratory principal component factor analysis (PCA) on all the 90 items included in the SCL-90 questionnaire led to a five-factor solution...
2017: Frontiers in Psychiatry
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