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Diabetic kidney nephropathy a case report

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https://www.readbyqxmd.com/read/27833523/role-of-cytogenetic-biomarkers-in-management-of-chronic-kidney-disease-patients-a-review
#1
REVIEW
Zeba Khan, Manoj Pandey, Ravindra M Samartha
Chronic kidney disease (CKD) is much more common than people recognize, and habitually goes undetected and undiagnosed until the disease is well advanced or when their kidney functions is down to 25% of normal function. Genetic and non-genetic factors contribute to cause CKD. Non-genetic factors include hypertension, High level of DNA damage due to the production of reactive oxygen species and nucleic acid oxidation has been reported in CKD patients. Main genetic factor which causes CKD is diabetic nephropathy...
October 2016: International Journal of Health Sciences
https://www.readbyqxmd.com/read/27747728/colchicine-induced-acute-neuromyopathy-in-a-patient-using-concomitant-fluconazole-case-report-and-literature-review
#2
Yi-Chia Su, Chih-Chien Wu
A 54-year-old woman presented at the emergency department after experiencing lower limb weakness and bilateral ankle pain for 2 days. She had a history of type 2 diabetes mellitus, diabetes mellitus nephropathy with chronic kidney disease, and chronic gouty arthritis. She had received 0.6 mg colchicine orally once or twice daily for 8 months. Four days prior to her emergency department visit, she was discharged from our nephrology ward, where she had been admitted because of a urinary tract infection. During hospitalization, she was treated with intravenous cefazolin for 7 days...
December 2015: Drug Safety—Case Reports
https://www.readbyqxmd.com/read/27721548/prescribing-patterns-of-medicines-in-chronic-kidney-disease-patients-on-maintenance-hemodialysis
#3
Sourav Chakraborty, Saugata Ghosh, Avishek Banerjea, Radha Raman De, Avijit Hazra, Swapan Kumar Mandal
OBJECTIVES: To study medicine prescribing pattern for chronic kidney disease (CKD) patients on maintenance hemodialysis. MATERIALS AND METHODS: This prospective observational study was conducted in hemodialysis unit of a teaching hospital with adult CKD patients on maintenance hemodialysis. Patients' clinical profile, drug-use pattern, and medication-related problem data were captured in a structured case report form and the data were analyzed descriptively. Adherence level was assessed by Morisky Medication-Taking Adherence Scale 4-item...
September 2016: Indian Journal of Pharmacology
https://www.readbyqxmd.com/read/27688084/-diabetic-nephropathy-in-a-non-diabetic-patient
#4
Olga Balafa, Georgios Liapis, Paraskevi Pavlakou, Georgios Baltatzis, Rigas Kalaitzidis, Moses Elisaf
Kimmelstiel and Wilson originally described nodular glomerulosclerosis as the pathognomonic lesion of diabetic nephropathy. Nevertheless, nodular glomerulosclerosis pattern can rarely occur in non-diabetic patients. In such cases, the differential diagnosis includes membranoproliferative glomerulonephritis, light or heavy chain deposition disease, amyloidosis, fibrillary and immunotactoid glomerulonephritis and chronic hypoxic or ischemic conditions. In cases that the above entities cannot be proven, the term idiopathic nodular glomerulosclerosis is given...
September 22, 2016: Pathology, Research and Practice
https://www.readbyqxmd.com/read/27472705/acute-thrombosis-of-a-transplanted-renal-artery-after-gastric-ulcer-bleeding-in-a-patient-with-a-long-term-well-functioning-renal-allograft-a-case-report-and-literature-review
#5
Chung-Kuan Wu, Jyh-Gang Leu, Cheng-Chun Wei, Shih-Chung Hsieh
BACKGROUND: Acute thrombosis of a transplanted renal artery is a serious vascular complication following renal allograft transplantation, which usually occurs within the first month after transplantation and often results in graft loss. It rarely occurs beyond the first month, except in a rejected kidney or in a kidney with high-grade transplant renal artery stenosis. RESULT: A 65-year-old male with a history of type 2 diabetes mellitus, hypertension, pulmonary tuberculosis, and end-stage renal disease was previously treated with hemodialysis (HD)...
July 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27469157/hiv-associated-renal-disease-an-overview
#6
Nicola Wearne, Ikechi G Okpechi
The cause of the human immunodeficiency virus (HIV) epidemic in South Africa (SA) was worsened by the denial by key political players that HIV causes acquired immunodeficiency syndrome (AIDS). South Africa continues to have the highest rate of HIV world-wide, which has had a huge impact on the development of both chronic kidney disease and acute kidney injury. Fortunately, there is now an effective antiretroviral therapy (ART) roll-out program. SA is also dealing with a collision of epidemics of HIV, tuberculosis, and non-communicable disease, particularly hypertension and diabetes...
2016: Clinical Nephrology
https://www.readbyqxmd.com/read/27436034/rare-allergic-reaction-of-the-kidney-sitagliptin-induced-acute-tubulointerstitial-nephritis
#7
Ali A Alsaad, Sarah M Dhannoon, Sally-Ann L Pantin, Ivan E Porter
A 56-year-old man with a history of diabetes mellitus type-2 and stage-2 chronic kidney disease secondary to diabetic nephropathy presented with an acute deterioration of kidney function. Non-invasive work-up failed to reveal the underlying aetiology for the acute kidney failure. Kidney biopsy revealed acute tubulointerstitial nephritis (ATIN) which was attributed to sitagliptin use. Only few case reports have shown this correlation. Our aim is to alert physicians and other providers of the potential effect of sitagliptin to cause ATIN with this biopsy-proven case...
2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27389722/efficacy-of-extracorporeal-albumin-dialysis-for-acute-kidney-injury-due-to-cholestatic-jaundice-nephrotoxicity
#8
Florence Sens, Justine Bacchetta, Maud Rabeyrin, Laurent Juillard
We report a case of a 37-year-old man with Maturity Onset Diabetes of the Youth (MODY) type 5, admitted for an episode of cholestasis and a simultaneous acute kidney injury (AKI). Chronic liver disease was due to a mutation in the transcription factor 2 (TCF2) gene, thus highlighting the need for a close liver follow-up in these patients. AKI was attributed to a cholemic nephropathy based on the following rationale: (1) alternative diagnoses were actively ruled out; (2) the onset of AKI coincided with the onset of severe hyperbilirubinaemia; (3) renal pathology showed large bile tubular casts and a marked tubular necrosis and (4) creatinine serum dramatically decreased when bilirubin levels improved after the first sessions of extracorporeal albumin dialysis (ECAD), thus suggesting its role in renal recovery...
2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27209436/incidence-mortality-and-prevalence-of-end-stage-chronic-renal-disease-in-the-bajo-lempa-region-of-el-salvador-a-ten-year-community-registry
#9
Ramón García-Trabanino, Carolina Hernández, Adrián Rosa, Jesús Domínguez Alonso
: The Bajo Lempa is an impoverished rural coastal region of El Salvador affected by the chronic kidney disease (CKD) epidemic known as Mesoamerican nephropathy. The local community organisation Fondo Social de Emergencia para la Salud (FSES) (Emergency social fund for health) is helping to fight the epidemic in 42 communities of the region (19,223 inhabitants; average age 26.7 years; 48.5% male; 40.2% <18 years). OBJECTIVES: To report annual rates of end-stage renal disease (ESRD) incidence and patient mortality in these communities during a 10-year period (2004-2013), and the prevalence of patients receiving renal replacement therapy (RRT) as of 31 December 2013...
May 18, 2016: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/27165826/an-autopsy-study-suggests-that-diabetic-nephropathy-is-underdiagnosed
#10
Celine Q F Klessens, Tess D Woutman, Kimberley A M Veraar, Malu Zandbergen, Elisabeth J J Valk, Joris I Rotmans, Ron Wolterbeek, Jan A Bruijn, Ingeborg M Bajema
The reported prevalence of diabetic nephropathy (DN) among patients with diabetes varies widely. Most studies use the presence of microalbuminuria for clinical onset of DN in the absence of a histopathologic evaluation. In this autopsy study, we collected and analyzed data from a cohort of patients with type 1 or 2 diabetes and determined the prevalence of histologically proven DN in patients with or without clinical manifestations of renal disease. We also examined the distribution among histopathologic classes with respect to clinical parameters...
July 2016: Kidney International
https://www.readbyqxmd.com/read/27069968/iga-dominant-post-infectious-glomerulonephritis-making-another-case-in-support-of-renal-biopsy-in-type-2-diabetic-nephropathy
#11
Ali Nayer, Gargi Davda, Rima Pai, Luis M Ortega
BACKGROUND: Approximately one-third of individuals with type 2 diabetes mellitus will eventually develop diabetic nephropathy (DN). Impaired renal function in type 2 diabetics may also be secondary to non-diabetic renal disease (NDRD). NDRD in type 2 diabetics may occur alone in the absence of DN or may be superimposed on DN. Renal biopsy maybe indicated to establish the correct diagnosis and to ascertain the severity of glomerular and tubulointerstitial pathology. CASE: We report a patient with type 2 diabetes mellitus and chronic renal insufficiency who developed worsening of renal function in the setting of staphylococcal infection and antibiotic use...
2016: Journal of Renal Injury Prevention
https://www.readbyqxmd.com/read/27015134/renal-pathology-in-hematopoietic-cell-transplant-recipients-a-contemporary-biopsy-nephrectomy-and-autopsy-series
#12
Brian T Brinkerhoff, Donald C Houghton, Megan L Troxell
Renal injury in hematopoietic cell transplant recipients may be related to a combination of factors including chemotherapy, radiation, infection, immunosuppressive agents, ischemia, and graft-versus-host disease, and can involve glomerular, tubulointerstitial, and vascular structures. We reviewed renal pathology from 67 patients at a single institution (2009-2014), including 14 patients with biopsy for clinical dysfunction, 6 patients with surgical kidney resection for other causes, and 47 autopsy patients...
June 2016: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/26988973/a-best-practice-position-statement-on-pregnancy-in-chronic-kidney-disease-the-italian-study-group-on-kidney-and-pregnancy
#13
REVIEW
Gianfranca Cabiddu, Santina Castellino, Giuseppe Gernone, Domenico Santoro, Gabriella Moroni, Michele Giannattasio, Gina Gregorini, Franca Giacchino, Rossella Attini, Valentina Loi, Monica Limardo, Linda Gammaro, Tullia Todros, Giorgina Barbara Piccoli
Pregnancy is increasingly undertaken in patients with chronic kidney disease (CKD) and, conversely, CKD is increasingly diagnosed in pregnancy: up to 3 % of pregnancies are estimated to be complicated by CKD. The heterogeneity of CKD (accounting for stage, hypertension and proteinuria) and the rarity of several kidney diseases make risk assessment difficult and therapeutic strategies are often based upon scattered experiences and small series. In this setting, the aim of this position statement of the Kidney and Pregnancy Study Group of the Italian Society of Nephrology is to review the literature, and discuss the experience in the clinical management of CKD in pregnancy...
June 2016: Journal of Nephrology
https://www.readbyqxmd.com/read/26894147/renal-papillary-necrosis-role-of-radiology
#14
Harsh C Sutariya, Vaidehi K Pandya
Renal Papillary Necrosis (RPN) is idefined as Ischemic necrobiosis of the papilla in the medulla of the kidneys. Variety of etiological factors are recognized which cause papillary necrosis, such as analgesic nephropathy, diabetes mellitus, urinary obstruction and sickle cell haemoglobinopathy. The early diagnosis of RPN is important to improve prognosis and reduce morbidity. Radiological Imaging offers early diagnosis and can guide prompt treatment of papillary necrosis and can minimize a decline in renal function...
January 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/26680759/star-fruit-toxicity-a-cause-of-both-acute-kidney-injury-and-chronic-kidney-disease-a-report-of-two-cases
#15
R A Abeysekera, S Wijetunge, N Nanayakkara, A W M Wazil, N V I Ratnatunga, T Jayalath, A Medagama
BACKGROUND: Star fruit (Averrhoa carambola) is commonly consumed as a herbal remedy for various ailments in tropical countries. However, the dangers associated with consumption of star fruit are not commonly known. Although star fruit induced oxalate nephrotoxicity in those with existing renal impairment is well documented, reports on its effect on those with normal renal function are infrequent. We report two unique clinical presentation patterns of star fruit nephrotoxicity following consumption of the fruit as a remedy for diabetes mellitus-the first, in a patient with normal renal function and the second case which we believe is the first reported case of chronic kidney disease (CKD) due to prolonged and excessive consumption of star fruits...
December 17, 2015: BMC Research Notes
https://www.readbyqxmd.com/read/26586063/analysis-of-histopathological-pattern-of-kidney-biopsy-specimens-in-kuwait-a-single-center-five-year-prospective-study
#16
Emad Abdallah, Bassam Al-Helal, Reem Asad, Shreeram Kannan, Wael Draz, Zeyad Abdelgawad
Glomerulonephritis (GN) varies in incidence in different geographical areas due to different socioeconomic conditions and ethnicity, genetic variability and environmental factors. Our study is aimed to determine the histopathological pattern of kidney biopsies in Kuwait over the preceding five years. In a prospective study, we analyzed the clinical and pathological data of 214 kidney biopsies that were performed during the period from November 2009 to November 2014 at the Al-Khezam Dialysis Center, Al-Adan Hospital, Kuwait...
November 2015: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/26494591/sodium-thiosulfate-is-effective-in-calcific-uremic-arteriolopathy-complicating-chronic-hemodialysis
#17
Stéphanie Malbos, Pablo Ureña-Torres, Thomas Bardin, Hang-Korng Ea
BACKGROUND: Calcific uremic arteriolopathy (CUA) or calciphylaxis is a severe complication of advanced chronic kidney disease (CKD) and dialysis. Few effective treatments are available and the mortality rate is high. We report 4 cases in which sodium thiosulfate therapy was rapidly effective. CASES: Sodium thiosulfate therapy was given to 4 Caucasian patients (3 females and 1 male aged 49 to 91 years) with CUA. The causes of end-stage CKD were nephroangiosclerosis (n=2) and diabetic nephropathy (n=2)...
January 2016: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/26319241/hepatocyte-nuclear-factor-1%C3%AE-associated-kidney-disease-more-than-renal-cysts-and-diabetes
#18
REVIEW
Jacobien C Verhave, Anneke P Bech, Jack F M Wetzels, Tom Nijenhuis
Hepatocyte nuclear factor 1β (HNF1β)-associated disease is a recently recognized clinical entity with a variable multisystem phenotype. Early reports described an association between HNF1B mutations and maturity-onset diabetes of the young. These patients often presented with renal cysts and renal function decline that preceded the diabetes, hence it was initially referred to as renal cysts and diabetes syndrome. However, it is now evident that many more symptoms occur, and diabetes and renal cysts are not always present...
February 2016: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/26240774/transplantation-of-horseshoe-kidney-from-living-genetically-unrelated-donor
#19
Kazuro Kikkawa, Takahito Wakamiya, Hiroki Kusumoto, Nagahide Matsumura, Yasuo Kohjimoto, Isao Hara
We report a case of renal transplantation using a horseshoe kidney from a living, genetically unrelated donor. The recipient was a 60-year-old man with diabetic nephropathy, and the donor was the 63-year-old wife of the recipient with a horseshoe kidney free of complications. Computed tomography showed two renal arteries and one renal vein on the left side, and the isthmus was perfused by several accessory arteries and veins. To demarcate the boundary of the isthmus, the left renal artery was ligated and cannulated for in situ perfusion...
2015: Case Reports in Transplantation
https://www.readbyqxmd.com/read/26177437/-evolution-of-contrast-nephropathy-in-patients-with-chronic-kidney-disease-undergoing-a-percutaneous-coronary-intervention
#20
Bibiana López-López, María Juana Pérez-López, Andrés García-Rincón, Benjamín Vázquez-Vega
INTRODUCTION: Current epidemiological transition from infectious to chronic-degenerative diseases is more and more demanding procedures requiring contrast medium, which turns out to be a risk factor for acute renal major damage in patients with chronic kidney disease. The aim of this article is to describe the frequency and evolution of Contrast-induced nephropathy in ambulatory patients with chronic kidney disease undergoing percutaneous coronary intervention. METHODS: We included patients with renal damage at the time of exposure to the contrast medium...
July 2015: Revista Médica del Instituto Mexicano del Seguro Social
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