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https://www.readbyqxmd.com/read/28225786/female-reproductive-factors-are-associated-with-objectively-measured-physical-activity-in-middle-aged-women
#1
Eija K Laakkonen, Janne Kulmala, Pauliina Aukee, Harto Hakonen, Urho M Kujala, Dawn A Lowe, Vuokko Kovanen, Tuija Tammelin, Sarianna Sipilä
Physical activity improves health and may delay the onset of several chronic diseases. For women in particular, the rate of these diseases accelerates at middle age; therefore it is important to identify the determinants of health-enhancing physical activity during midlife in this population. In this study, we focused on determinants that are unique to the female sex, such as childbearing and menopause. The main objective was to characterize the level of physical activity and differences between active and inactive middle-aged Finnish women...
2017: PloS One
https://www.readbyqxmd.com/read/28223506/intragenic-cpg-islands-play-important-roles-in-bivalent-chromatin-assembly-of-developmental-genes
#2
Sun-Min Lee, Jungwoo Lee, Kyung-Min Noh, Won-Young Choi, Sejin Jeon, Goo Taeg Oh, Jeongsil Kim-Ha, Yoonhee Jin, Seung-Woo Cho, Young-Joon Kim
CpG, 5'-C-phosphate-G-3', islands (CGIs) have long been known for their association with enhancers, silencers, and promoters, and for their epigenetic signatures. They are maintained in embryonic stem cells (ESCs) in a poised but inactive state via the formation of bivalent chromatin containing both active and repressive marks. CGIs also occur within coding sequences, where their functional role has remained obscure. Intragenic CGIs (iCGIs) are largely absent from housekeeping genes, but they are found in all genes associated with organ development and cell lineage control...
February 21, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28219013/changes-in-smoking-drinking-overweight-and-physical-inactivity-in-young-australian-women-1996-2013
#3
Jennifer R Powers, Deborah Loxton, Amy E Anderson, Annette J Dobson, Gita D Mishra, Richard Hockey, Wendy J Brown
Issue addressed: Smoking, risky drinking, overweight and obesity, and physical inactivity are health-risk factors (HRFs) that contribute significantly to morbidity worldwide. Several initiatives have been introduced over the past two decades to reduce these HRFs. This paper examines changes in the prevalence of HRFs in young women (aged 18-23 years) between 1996 and 2013, overall and within demographic groups.Methods: Data from two cohorts of the Australian Longitudinal Study on Women's Health, born in 1973-78 (n=14247) and 1989-95 (n=17012) were weighted to provide national estimates...
February 20, 2017: Health Promotion Journal of Australia
https://www.readbyqxmd.com/read/28218985/soft-palatal-melanosis-a-simple-predictor-for-neoplasia-in-the-upper-aerodigestive-tract-in-japanese-alcoholic-men
#4
Kenro Hirata, Akira Yokoyama, Rieko Nakamura, Tai Omori, Hirofumi Kawakubo, Takeshi Mizukami, Katsuya Maruyama, Takanori Kanai, Tetsuji Yokoyama
Soft palatal melanosis can be detected by visual inspection during routine physical examination or even personally in a mirror. The aim of this study was to evaluate the association between squamous cell neoplasia in the upper aerodigestive tract (UAT) and the soft palatal melanosis. We reviewed digitalized records of high-quality endoscopic images of the soft palate of 1786 Japanese alcoholic men who underwent endoscopic screening. Soft palatal melanosis was observed in 381 (21.3%) of the subjects (distinct, 6...
February 20, 2017: Cancer Science
https://www.readbyqxmd.com/read/28218795/defensive-coping-and-essential-amino-acid-markers-as-possible-predictors-for-structural-vascular-disease-in-an-african-and-caucasian-male-cohort-the-sabpa-study
#5
Marisa Möller, Leoné Malan, Martin Magnusson, Carina M C Mels, Nico T Malan
Defensive coping (DefS), oxidative stress, inflammation, and related amino acids (phenylalanine [Phe] and tyrosine [Tyr]) have been implicated in cardiovascular disease. This study assessed whether inflammation, oxidative stress, changes in essential amino acids, and altered coping strategies are correlated with subclinical vascular changes in African (n = 82) and Caucasian (n = 100) men from the Sympathetic Activity and Ambulatory Blood Pressure in Africans (SABPA) study. The Coping Strategy Indicator questionnaire identified DefS participants...
February 20, 2017: Psychophysiology
https://www.readbyqxmd.com/read/28217584/physical-activity-correlates-of-overweight-and-obesity-in-school-going-children-of-dehradun-uttarakhand
#6
Madhavi Bhargava, S D Kandpal, Pradeep Aggarwal
BACKGROUND: Physical activity is important for prevention of overweight and obesity in growing children. OBJECTIVE: The present study aims to explore the association of overweight and obesity in school children of the district of Dehradun with physical activity, sports, and recreation at home and school. MATERIALS AND METHODS: A cross-sectional survey of 1266 schoolchildren of select private and government schools in urban and rural areas was done...
July 2016: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/28215636/sirtuin-6-prevents-matrix-degradation-through-inhibition-of-the-nf-%C3%AE%C2%BAb-pathway-in-intervertebral-disc-degeneration
#7
Liang Kang, Jia Hu, Yuxiong Weng, Jie Jia, Yukun Zhang
Intervertebral disc degeneration (IDD) is marked by imbalanced metabolism of the extracellular matrix (ECM) in the nucleus pulposus (NP) of intervertebral discs. This study aimed to determine whether sirtuin 6 (SIRT6), a member of the sirtuin family of nicotinamide adenine dinucleotide-dependent deacetylases, protects the NP from ECM degradation in IDD. Our study showed that expression of SIRT6 markedly decreased during IDD progression. Overexpression of wild-type SIRT6, but not a catalytically inactive mutant, prevented IL-1β-induced NP ECM degradation...
February 16, 2017: Experimental Cell Research
https://www.readbyqxmd.com/read/28215385/research-to-practice-implementing-physical-activity-recommendations
#8
Sally M Davis, Theresa H Cruz, Richard L Kozoll
INTRODUCTION: Dissemination and implementation science focuses on bridging the gap between research and practice. The Community Preventive Services Task Force published recommendations for increasing physical activity based on scientific review and consensus. Little research on the dissemination and implementation of these recommendations has been conducted in under-represented populations at high risk for inactivity and chronic disease. METHODS: Partnering with one rural community (beta site), the University of New Mexico Prevention Research Center studied the translation of Community Preventive Services Task Force recommendations to practice...
March 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28215247/physical-activity-smoking-and-the-incidence-of-clinically-diagnosed-insomnia
#9
Li-Jung Chen, Andrew Steptoe, Yi-Huei Chen, Po-Wen Ku, Ching-Heng Lin
OBJECTIVE: This study was designed to examine the independent and combined associations of physical activity and smoking on the incidence of doctor-diagnosed insomnia using a nationally representative sample over seven years, taking into account other relevant covariates. METHODS: Participants aged 18 years or older in the 2005 Taiwan National Health Interview Survey (NHIS) with links to National Health Insurance (NHI) claim data between 2005 and 2012 and without diagnosed insomnia before 2005, were selected into this study (n = 12,728)...
February 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28215189/socio-economic-differences-in-diet-physical-activity-and-leisure-time-screen-use-among-scottish-children-in-2006-and-2010-are-we-closing-the-gap
#10
Geraldine McNeill, Lindsey F Masson, Jennie I Macdiarmid, Leone Ca Craig, Wendy J Wills, Catherine Bromley
OBJECTIVE: To investigate socio-economic differences in children's diet, activity and inactivity and changes in these differences over 4 years during which new policies on food in schools were introduced. DESIGN: Two cross-sectional surveys in which diet was assessed by FFQ and physical activity and inactivity were assessed by interviewer-administered questionnaire. Socio-economic status was assessed by the area-based Scottish Index of Multiple Deprivation. SETTING: Scotland, 2006 and 2010...
February 20, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28214544/can-functional-magnetic-resonance-imaging-studies-help-with-the-optimization-of-health-messaging-for-lifestyle-behavior-change-a-systematic-review
#11
REVIEW
Maxine E Whelan, Paul S Morgan, Lauren B Sherar, Mark W Orme, Dale W Esliger
Unhealthy behaviors, including smoking, poor nutrition, excessive alcohol consumption, physical inactivity and sedentary lifestyles, are global risk factors for non-communicable diseases and premature death. Functional magnetic resonance imaging (fMRI) offers a unique approach to optimize health messages by examining how the brain responds to information relating to health. Our aim was to systematically review fMRI studies that have investigated variations in brain activation in response to health messages relating to (i) smoking; (ii) alcohol consumption; (iii) physical activity; (iv) diet; and (v) sedentary behavior...
February 15, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28214186/characteristics-and-prognosis-of-japanese-colorectal-cancer-patients-the-biobank-japan-project
#12
Akiko Tamakoshi, Koshi Nakamura, Shigekazu Ukawa, Emiko Okada, Makoto Hirata, Akiko Nagai, Koichi Matsuda, Yoichiro Kamatani, Kaori Muto, Yutaka Kiyohara, Zentaro Yamagata, Toshiharu Ninomiya, Michiaki Kubo, Yusuke Nakamura
BACKGROUND: Colorectal cancer is the third most common cancer worldwide, and in Japan, it is estimated that about 10% of men and 8% of women will be diagnosed with colorectal cancer during their lifetime. METHODS: We focused on 5864 participants (3699 men and 2165 women) who had colorectal cancer and were registered with BioBank Japan (BBJ) between April 2003 and March 2008. Characteristics of colon and rectal cancer patients were calculated separately. Among the enrolled patients registered in BBJ within 90 days after diagnosis, we also calculated the 5-year cumulative and relative survival rates, and estimated the effect of lifestyle factors on all-cause mortality...
February 14, 2017: Journal of Epidemiology
https://www.readbyqxmd.com/read/28213631/destroying-god-s-temple-physical-inactivity-poor-diet-obesity-and-other-sin-behaviors
#13
Mark D Faries, Megan McClendon, Eric J Jones
On average, our participants (N = 112), who self-proclaimed to be Christians, believed that physically inactive lifestyles, unhealthy eating, overeating, and being obese destroy the body, God's temple. However, these beliefs were less definitive, than those of other common "sin" behaviors, such as drug use, smoking, and excessive drinking of alcohol. In addition, destroying the body with physical inactivity or poor diet was not necessarily viewed as sinful. Subsequently, these beliefs did not relate to self-reported physical activity, dietary behavior, or body mass index...
February 17, 2017: Journal of Religion and Health
https://www.readbyqxmd.com/read/28212674/proportion-of-dementia-in-australia-explained-by-common-modifiable-risk-factors
#14
Kimberly Ashby-Mitchell, Richard Burns, Jonathan Shaw, Kaarin J Anstey
BACKGROUND: At present, dementia has no known cure. Interventions to delay onset and reduce prevalence of the disease are therefore focused on risk factor reduction. Previous population attributable risk estimates for western countries may have been underestimated as a result of the relatively low rates of midlife obesity and the lower weighting given to that variable in statistical models. METHODS: Levin's Attributable Risk which assumes independence of risk factors was used to calculate the proportion of dementia attributable to seven modifiable risk factors (midlife obesity, physical inactivity, smoking, low educational attainment, diabetes mellitus, midlife hypertension and depression) in Australia...
February 17, 2017: Alzheimer's Research & Therapy
https://www.readbyqxmd.com/read/28212346/the-relationship-between-physical-activity-and-plasma-glucose-level-amongst-ellisras-rural-young-adult-males-and-females-ellisras-longitudinal-study
#15
Moloko Matshipi, Kotsedi Daniel Monyeki, Han Kemper
Unhealthy lifestyle characteristics such as low physical activity (PA) and high plasma glucose levels (PGLs) may lead to the development of type 2 diabetes mellitus in adulthood. The aim of this study was to investigate (i) the level of physical activity; (ii) the prevalence of pre-diabetes and (iii) the relationship between PA and plasma glucose level in a rural Ellisras adult population aged 18 to 28 years. A total of 713 young adults (349 males and 364 females) who took part in the Ellisras Longitudinal Study participated in the study...
February 16, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28211549/review-of-health-and-risk-behaviours-mental-health-problems-and-suicidal-behaviours-in-young-europeans-on-the-basis-of-the-results-from-the-eu-funded-saving-and-empowering-young-lives-in-europe-seyle-study
#16
REVIEW
Danuta Wasserman
An estimated 800 000 suicide deaths occur worldwide. The global suicide rate is 11.4 per 100 000 population; 15.0/100 000 for males and 8.0/100 000 for females. Globally, suicide is the second leading cause of death in 15-29 year olds. In a collaborative effort to reduce the high rates of suicide and mental health problems among youth across Europe, the European Union 7th Framework funded the Saving and Empowering Young Lives in Europe (SEYLE) project. SEYLE is a randomized controlled trial (RCT) aimed to promote mental health and healthy lifestyles, while preventing psychopathology and suicidal behaviours among adolescents...
December 23, 2016: Psychiatria Polska
https://www.readbyqxmd.com/read/28209767/ideal-cardiovascular-health-cardiovascular-remodeling-and-heart-failure-in-blacks-the-jackson-heart-study
#17
Aferdita Spahillari, Sameera Talegawkar, Adolfo Correa, J Jeffrey Carr, James G Terry, João Lima, Jane E Freedman, Saumya Das, Robb Kociol, Sarah de Ferranti, Donya Mohebali, Stanford Mwasongwe, Katherine L Tucker, Venkatesh L Murthy, Ravi V Shah
BACKGROUND: The lifetime risk of heart failure (HF) is higher in the black population than in other racial groups in the United States. METHODS AND RESULTS: We measured the Life's Simple 7 ideal cardiovascular health metrics in 4195 blacks in the JHS (Jackson Heart Study; 2000-2004). We evaluated the association of Simple 7 metrics with incident HF and left ventricular structure and function by cardiac magnetic resonance (n=1188). Mean age at baseline was 54.4 years (65% women)...
February 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/28209386/dietary-therapy-in-heart-failure-with-preserved-ejection-fraction-and-or-left-ventricular-diastolic-dysfunction-in-patients-with-metabolic-syndrome
#18
REVIEW
Helene von Bibra, Alexander Ströhle, Martin St John Sutton, Nicolai Worm
BACKGROUND: Heart failure is an ongoing epidemic of left ventricular (LV) dilatation and/or dysfunction due to the increasing prevalence of predisposing risk factors such as age, physical inactivity, (abdominal) obesity, and type-2-diabetes. Approximately half of these patients have diastolic heart failure (HFpEF). The prognosis of HFpEF is comparable to that of systolic heart failure, but without any known effective treatment. DIASTOLIC DYSFUNCTION: A biomathematically corrected diagnostic approach is presented that quantifies diastolic dysfunction via the predominant age dependency of LV diastolic function and unmasks (metabolic) risk factors, that are independent of age and, therefore, potential targets for therapy...
January 5, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28207665/healthy-physical-activity-levels-below-recommended-thresholds-two-years-after-lumbar-spine-surgery
#19
Carol A Mancuso, Roland Duculan, Federico P Girardi
STUDY DESIGN: Prospective analysis. OBJECTIVE: To quantify physical activity after lumbar surgery and identify spine-related variables associated with not meeting recommended activity thresholds. SUMMARY OF BACKGROUND DATA: National guidelines recommend ≥150 minutes/week of moderate-intensity activity; however, only 52% of the general population meets this threshold. For patients not participating in exercise/sports, ≥1400 kcal/week of energy expenditure, including from walking, is another threshold...
February 15, 2017: Spine
https://www.readbyqxmd.com/read/28207494/causes-and-consequences-of-fatigue-in-rheumatoid-arthritis
#20
Patricia Katz
PURPOSE OF REVIEW: To review current information on the causes, treatments, and consequences of fatigue in rheumatoid arthritis. RECENT FINDINGS: Disease activity (inflammation, pain, joint symptoms) is associated with greater fatigue. However, disease activity per se accounts for only a small portion of fatigue, and rheumatoid arthritis medications that reduce disease activity have small effects on fatigue. Instead, factors outside the direct effects of rheumatoid arthritis, such as obesity, physical inactivity, sleep disturbance, and depression, explain the majority of variation in fatigue...
February 15, 2017: Current Opinion in Rheumatology
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