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Bone Strength

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https://www.readbyqxmd.com/read/29149487/fabrication-of-chelate-setting-%C3%AE-tricalcium-phosphate-cement-using-sodium-citrate-and-sodium-alginate-as-mixing-solution-and-its-in-vivo-osteoconductivity
#1
Toshiisa Konishi, Poon Nian Lim, Michiyo Honda, Masaki Nagaya, Hiroshi Nagashima, Eng San Thian, Mamoru Aizawa
Moldable and injectable calcium-phosphate cements (CPCs) are material candidates for bone replacement applications. In the present study, we examined the effectiveness of sodium alginate and sodium citrate additives to the liquid phase of CPC, in improving its handling property as well as mechanical strength. The use of these additives enhanced the handling property significantly, in terms of consistency as compared to CPC without additives due to the liquefying effect caused by the adsorption of citrate ions on the cement particles...
November 17, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29149204/evaluation-of-osseous-integration-of-titanium-orthopedic-screws-with-novel-sla-treatment-in-porcine-model
#2
Tzu-Hsiang Lin, Hsin-Tai Hu, Hsueh-Chun Wang, Meng-Chian Wu, Shu-Wei Wu, Ming-Long Yeh
The success of many endosseous implants in orthopaedic and dental applications depends on the surface characteristics, as they affect osseous integration. Previous investigations indicated that a novel large-grit sand-blasted and acid-etched (SLA) titanium (denoted as SLAffinity-Ti) implant had better bone integration than that of a comparably shaped implant with a plasma-sprayed titanium surface. The purpose of the present investigation was to create a SLAffinity surface on pedicle screws and trauma screws and to compare it with the surfaces of a sand-blasted-only implant and commercial implants in terms of bone integration...
2017: PloS One
https://www.readbyqxmd.com/read/29149200/heterozygous-deletion-of-both-sclerostin-sost-and-connexin43-gja1-genes-in-mice-is-not-sufficient-to-impair-cortical-bone-modeling
#3
Susan K Grimston, Francesca Fontana, Marcus Watkins, Roberto Civitelli
Connexin43 (Cx43) is the main gap junction protein expressed in bone forming cells, where it modulates peak bone mass acquisition and cortical modeling. Genetic ablation of the Cx43 gene (Gja1) results in cortical expansion with accentuated periosteal bone formation associated with decreased expression of the Wnt inhibitor sclerostin. To determine whether sclerostin (Sost) down-regulation might contribute to periosteal expansion in Gja1 deficient bones, we took a gene interaction approach and crossed mice harboring germline null alleles for Gja1 or Sost to generate single Gja1+/-and Sost+/-and double Gja1+/-;Sost+/-heterozygous mice...
2017: PloS One
https://www.readbyqxmd.com/read/29145437/assessment-of-the-suitability-of-biodegradable-rods-for-use-in-posterior-lumbar-fusion-an-in-vitro-biomechanical-evaluation-and-finite-element-analysis
#4
Fon-Yih Tsuang, Yueh-Ying Hsieh, Yi-Jie Kuo, Chia-Hsien Chen, Feng-Huei Lin, Chen-Sheng Chen, Chang-Jung Chiang
Interbody fusion with posterior instrumentation is a common method for treating lumbar degenerative disc diseases. However, the high rigidity of the fusion construct may produce abnormal stresses at the adjacent segment and lead to adjacent segment degeneration (ASD). As such, biodegradable implants are becoming more popular for use in orthopaedic surgery. These implants offer sufficient stability for fusion but at a reduced stiffness. Tailored to degrade over a specific timeframe, biodegradable implants could potentially mitigate the drawbacks of conventional stiff constructs and reduce the loading on adjacent segments...
2017: PloS One
https://www.readbyqxmd.com/read/29145347/fingertip-winding-suture-pull-out-suture-technique-for-flexor-tendon-repair-in-zone-i
#5
Mostafa Mahmoud, Motaz Elian, Abdalah Seif Elnasr
Injuries to flexor tendons in zone I has always been challenging during repair. Over the time several techniques were developed and modified to achieve the highest repair strength and thus the best functional outcome. These techniques vary from pull-out sutures with internal and external fixation to the use of bone anchors. All techniques were accompanied with advantages and disadvantages as well as postoperative morbidities related to certain techniques. In the present technique we introduce a subperiosteal pull-out suturing technique...
December 2017: Techniques in Hand & Upper Extremity Surgery
https://www.readbyqxmd.com/read/29144022/collagen-a-review-on-its-sources-and-potential-cosmetic-applications
#6
REVIEW
María Isabela Avila Rodríguez, Laura G Rodríguez Barroso, Mirna Lorena Sánchez
Collagen is a fibrillar protein that conforms the conjunctive and connective tissues in the human body, essentially skin, joints, and bones. This molecule is one of the most abundant in many of the living organisms due to its connective role in biological structures. Due to its abundance, strength and its directly proportional relation with skin aging, collagen has gained great interest in the cosmetic industry. It has been established that the collagen fibers are damaged with the pass of time, losing thickness and strength which has been strongly related with skin aging phenomena [Colágeno para todo...
November 16, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29143443/multiscale-characterisation-of-cortical-bone-composition-microstructure-and-nanomechanical-properties-in-experimentally-induced-osteoporosis
#7
Furqan A Shah, Adrian Stoica, Carina Cardemil, Anders Palmquist
Cortical bone plays a vital role in determining overall bone strength. We investigate the structural, compositional, and nanomechanical properties of cortical bone following ovariectomy (OVX) of 12 week old Sprague Dawley rats, since this animal model is frequently employed to evaluate the performance of implantable biomaterials in compromised bone healing conditions. Morphological parameters and material properties of bone in the geometrical centre of the femoral cortex were investigated four and eight weeks post-OVX and in unoperated controls (Ctrl), using X-ray micro-computed tomography, backscattered electron scanning electron microscopy, Raman spectroscopy, and nanoindentation...
November 16, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/29143259/adsorption-reduction-of-hg-ii-and-pb-ii-from-aqueous-solutions-by-using-bone-ash-nzvi-composite-effects-of-aging-time-fe-loading-quantity-and-co-existing-ions
#8
Antonio Gil, Mohammad Javad Amiri, Jahangir Abedi-Koupai, Saeid Eslamian
In this research, a versatile and highly efficient method for the stabilization of nanoscale zerovalent iron particles (nZVI) on the surface of ostrich bone ash (OBA) was presented as a novel inorganic adsorbent (OBA/nZVI) for the removal of Hg(II) and Pb(II) ions from aqueous solutions, even after 1 year of storage under room conditions. The removal behavior of the OBA/nZVI was assessed as a function of the initial pH, contact time, initial pollutants concentration, temperature, amount of adsorbent, effect of competitive metal ions, and ionic strength...
November 15, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29143126/-spinal-orthoses-in-the-treatment-of-vertebral-fractures-with-osteoporosis-a-systematic-review-article
#9
REVIEW
M Pfeifer, M Gehlen, C Hinz
This literature search concerning the potential role of spinal orthoses for rehabilitation and treatment of atraumatic vertebral fractures between Th4 and L5 with osteoporosis and without any evidence for a secondary cause, provided no evidence for the benefits of traditional rigid thoracolumbar corsets, which only had a poor compliance. In addition, there are indications that these rigid corsets may even worsen the disease condition especially in the long-term. Wearing these corsets can result in further loss of muscle mass and strength followed by loss of bone and bone mass...
November 15, 2017: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/29141630/ct-based-analysis-of-muscle-volume-and-degeneration-of-gluteus-medius-in-patients-with-unilateral-hip-osteoarthritis
#10
Takako Momose, Yutaka Inaba, Hyonmin Choe, Naomi Kobayashi, Taro Tezuka, Tomoyuki Saito
BACKGROUND: The gluteus medius (GMED) affects hip function as an abductor. We evaluated muscle volume and degeneration of the GMED by using CT-based analysis and assessed factors that affect hip abductor strength in patients with unilateral hip osteoarthritis (OA). METHODS: We examined clinical and imaging findings associated with hip abductor strength in consecutive 50 patients with unilateral hip OA. Hip abductor muscle strength and Harris hip score (HHS) were assessed...
November 15, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29141602/association-between-sarcopenia-and-low-back-pain-in-local-residents-prospective-cohort-study-from-the-gaina-study
#11
Shinji Tanishima, Hiroshi Hagino, Hiromi Matsumoto, Chika Tanimura, Hideki Nagashima
BACKGROUND: Low back pain (LBP) is one of the most common ailments that people experience in their lifetime. On the other hands, Sarcopenia also leads to several physical symptoms and contributes to reducing the quality of life of elderly people.The purpose of this study is to investigate the association between sarcopenia and low back pain among the general population. METHODS: The subjects included 216 adults (79 men and 137 women; mean age, 73.5 years) undergoing a general medical examination in Hino, Japan...
November 15, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29140580/enhanced-biological-fixation-of-ligaments-to-bone-tissues-utilizing-chitin-fabrics
#12
Hisaya Nomata, Michiko Nakaishi, Kazuo Takakuda
In ligament reconstruction involving anterior cruciate ligament surgery, biological fixation between the transferred ligament and bone tissue is critical for achieving successful outcomes. Here, we administered chitin fabrics into the bone tunnels and evaluated their efficacy in promoting biological fixation. An animal model on the rat's patellar ligament was employed. First, bone tunnels were created in the lateral condyle of the femur. The ligament was then separated from the tibial tuberosity, and half was inserted into the tunnel and fixed with the use of end button...
November 15, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29140181/rational-design-of-a-high-strength-bone-scaffold-platform-based-on-in-situ-hybridization-of-bacterial-cellulose-nano-hydroxyapatite-framework-and-silk-fibroin-reinforcing-phase
#13
Pei Jiang, Jiabing Ran, Pan Yan, Lingyue Zheng, Xinyu Shen, Hua Tong
Bacterial cellulose/hydroxyapatite (BC/HAp) composite had favourable bioaffinity but its poor mechanical strength limited its widespread applications in bone tissue engineering (BTE). Silk fibroin, which possesses special crystalline structure, has been widely used as organic reinforcing material, and different SFs have different amino acid sequences, which exhibit different bioaffinity and mechanical properties. In this regard, bacterial cellulose-Antheraea yamamai silk fibroin/hydroxyapatite(BC-AYSF/HAp), bacterial cellulose-Bombyx mori silk fibroin/hydroxyapatite(BC-BMSF/HAp), and BC/HAp nano-composites were synthesized via a novel in situ hybridization method...
November 15, 2017: Journal of Biomaterials Science. Polymer Edition
https://www.readbyqxmd.com/read/29137893/advances-in-the-evaluation-of-bone-health-in-kidney-transplant-patients
#14
María José Pérez-Sáez, Daniel Prieto-Alhambra, Adolfo Díez-Pérez, Julio Pascual
Bone disease related to chronic kidney disease and, particularly, to kidney transplant patients is a common cause or morbidity and mortality, especially due to a higher risk of osteoporotic fractures. Despite the fact that this has been known for decades, to date, an appropriate diagnostic strategy has yet to be established. Apart from bone biopsy, which is invasive and scarcely used, no other technique is available to accurately establish the risk of fracture in kidney patients. Techniques applied to the general population, such as bone densitometry, have not been subjected to sufficient external validation and their use is not systematic...
November 11, 2017: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/29137784/surface-modified-sio2-nanoparticles-by-thiamine-and-ultrasonication-synthesis-of-pcl-sio2-vb1-ncs-morphology-thermal-mechanical-and-bioactivity-investigations
#15
Shadpour Mallakpour, Zahra Khani
The influence of silica (SiO2) nanoparticles (NPs) on the properties of polycaprolactone (PCL) was investigated. Due to the intense tendency of SiO2 NPs to aggregation and their high surface energy, the surface of SiO2 NPs was treatment via Vitamin B1 (VB1) as a biosafe coupling agent. Novel PCL/SiO2-VB1 nanocomposites (NC) films by variety of percentage of SiO2-VB1 NPs were prepared under ultrasonic irradiation as an eco-friendly and fast procedure following by casting method. Fourier transform infrared spectroscopy and energy dispersive X-ray analysis exposed the presence of SiO2 NPs into the polymer matrix...
March 2018: Ultrasonics Sonochemistry
https://www.readbyqxmd.com/read/29137724/simplified-boundary-conditions-alter-cortical-trabecular-load-sharing-at-the-distal-radius-a-multiscale-finite-element-analysis
#16
Joshua E Johnson, Karen L Troy
High-resolution peripheral quantitative computed tomography (HR-pQCT) derived micro-finite element (FE) modeling is used to evaluate mechanical behavior at the distal radius microstructure. However, these analyses typically simulate non-physiologic simplified platen-compression boundary conditions on a small section of the distal radius. Cortical and trabecular regions contribute uniquely to distal radius mechanical behavior, and various factors affect these regions distinctly. Generalized strength predictions from standardized platen-compression analyses may not adequately capture region specific responses in bone...
November 4, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/29137022/the-effect-of-whole-body-vibration-training-on-lean-mass-a-prisma-compliant-meta-analysis
#17
Hengting Chen, Jianxiong Ma, Bin Lu, Xin-Long Ma
BACKGROUND: Whole-body vibration training (WBVT) confers a continuous vibration stimuli to the body. Although some reports have discussed the effects of whole-body vibration (WBV) on bone mineral density and muscle strength, study of WBV effects on lean mass have not been determined. The purpose of the present meta-analysis was to evaluate published, randomized controlled trials (RCTs) that investigated the effects of WBVT on lean mass. METHODS: We identified only RCTs by searching databases, including Web of Science, PubMed, Scopus, Embase, and the Cochrane Library from inception to March 2017...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29135646/foot-structure-and-function-in-habitually-barefoot-and-shod-adolescents-in-kenya
#18
Herje Aibast, Paul Okutoyi, Timothy Sigei, Walter Adero, Danny Chemjor, Neford Ongaro, Noriyuki Fuku, Kenn Konstabel, Carol Clark, Daniel E Lieberman, Yannis Pitsiladis
Habitually barefoot (HB) children from the Kalenjin tribe of Kenya are known for their high physical activity levels. To date, there has been no comprehensive assessment of foot structure and function in these highly active and HB children/adolescents and link with overuse injuries. PURPOSE: The aim of this research is to assess foot structure, foot function, injury and physical activity levels in Kenyan children and adolescents who are HB compared with those who were habitually shod (HS)...
November 2017: Current Sports Medicine Reports
https://www.readbyqxmd.com/read/29134816/liquifying-pldlla-anchor-fixation-in-achilles-reconstruction-for-insertional-tendinopathy
#19
Stephanie A Boden, Allison L Boden, Danielle Mignemi, Jason T Bariteau
Insertional Achilles tendinopathy (IAT) is a frequent cause of posterior heel pain and is often associated with Haglund's deformity. Surgical correction for refractory cases of IAT has been well studied; however, the method of tendon fixation to bone in these procedures remains controversial, and to date, no standard technique has been identified for tendon fixation in these surgeries. Often, after Haglund's resection, there is large exposed cancellous surface for Achilles reattachment, which may require unique fixation to optimize outcomes...
November 1, 2017: Foot & Ankle Specialist
https://www.readbyqxmd.com/read/29134237/neuronal-cell-adhesion-molecule-1-regulates-leptin-sensitivity-and-bone-mass
#20
Xin Yan, Natalia L Kononenko, Annemarie Brüel, Jesper Skovhus Thomsen, Matthew N Poy
The central nervous system is widely known to exert control over our systemic physiology via several mechanisms including the regulation of skeletal metabolism. Neuronal circuits within the hypothalamus have been shown to impact bone mass via leptin-dependent and independent mechanisms; however, the full extent to which the brain controls bone homeostasis is not known. We previously identified cell adhesion molecule1 (Cadm1) as a regulator of body weight and energy homeostasis via its expression in multiple regions of the brain...
November 13, 2017: Calcified Tissue International
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