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https://www.readbyqxmd.com/read/28723915/key-findings-from-a-prospective-trauma-registry-at-a-regional-hospital-in-southwest-cameroon
#1
Alain Chichom-Mefire, Obieze C Nwanna-Nzewunwa, Vincent Verla Siysi, Isabelle Feldhaus, Rochelle Dicker, Catherine Juillard
INTRODUCTION: Trauma is a leading cause of morbidity and mortality worldwide. Data characterizing the burden of trauma in Cameroon is limited. Regular, prospective injury surveillance can address the shortcomings of existing hospital administrative logs and medical records. This study aims to characterize trauma as seen at the emergency department (ED) of Limbe Regional Hospital (LRH) and assess the completeness of data obtained by a trauma registry. METHODS AND FINDINGS: From January 2008 to October 2013, we prospectively captured data on injured patients using a strategically designed, context-relevant trauma registry instrument...
2017: PloS One
https://www.readbyqxmd.com/read/28688977/prevalence-of-drug-resistance-among-hiv-1-treatment-naive-patients-in-greece-during-2003-2015-transmitted-drug-resistance-is-due-to-onward-transmissions
#2
D Paraskevis, E Kostaki, G Magiorkinis, P Gargalianos, G Xylomenos, E Magiorkinis, M Lazanas, M Chini, G Nikolopoulos, A Skoutelis, V Papastamopoulos, A Antoniadou, A Papadopoulos, M Psichogiou, G L Daikos, M Oikonomopoulou, A Zavitsanou, G Chrysos, V Paparizos, S Kourkounti, H Sambatakou, N V Sipsas, M Lada, P Panagopoulos, E Maltezos, S Drimis, A Hatzakis
BACKGROUND: The prevalence of HIV-1 drug resistance among treatment-naïve patients ranges between 8.3% and 15% in Europe and North America. Previous studies showed that subtypes A and B were the most prevalent in the Greek HIV-1 epidemic. Our aim was to estimate the prevalence of resistance among drug naïve patients in Greece and to investigate the levels of transmission networking among those carrying resistant strains. METHODS: HIV-1 sequences were determined from 3428 drug naïve HIV-1 patients, in Greece sampled during 01/01/2003-30/6/2015...
July 5, 2017: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/28685902/can-pay-for-performance-to-primary-care-providers-stimulate-appropriate-use-of-antibiotics
#3
Lina Maria Ellegård, Jens Dietrichson, Anders Anell
Antibiotic resistance is a major threat to public health worldwide. As the healthcare sector's use of antibiotics is an important contributor to the development of resistance, it is crucial that physicians only prescribe antibiotics when needed and that they choose narrow-spectrum antibiotics, which act on fewer bacteria types, when possible. Inappropriate use of antibiotics is nonetheless widespread, not least for respiratory tract infections (RTI), a common reason for antibiotics prescriptions. We examine if pay-for-performance (P4P) presents a way to influence primary care physicians' choice of antibiotics...
July 7, 2017: Health Economics
https://www.readbyqxmd.com/read/28682290/prolonged-allograft-survival-in-a-patient-with-chronic-immunosuppression-a-case-report-and-systematic-review
#4
Krishna S Vyas, Chase Burns, Dylan T Ryan, Lesley Wong
A 41-year-old man with past medical history of kidney-liver transplantation requiring chronic immunosuppression presented 2 years posttransplant with a necrotizing soft tissue infection of his right thigh. Serial debridement to remove necrotic tissue was performed, and a Matrix HD Allograft Fenestrated (RTI Surgical, Alachua, FL) was applied. At 5-months post grafting, the patient demonstrated fully vascularized and intact skin. Under normal circumstances, a cadaveric allograft sloughs over several weeks and is not usually considered a permanent solution for wound closure...
June 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/28670621/changes-in-dti-diffusivity-and-fmri-connectivity-cluster-coefficients-for-students-with-and-without-specific-learning-disabilities-in-written-language-brain-s-response-to-writing-instruction
#5
Todd L Richards, Virginia W Berninger, Kevin J Yagle, Robert D Abbott, Daniel J Peterson
Before and after computerized writing instruction, participants completed assessment with normed measures and DTI and fMRI connectivity scanning. Evidence-based differential diagnosis was used at time 1 to assign them to diagnostic groups: typical oral and written language (n=6), dysgraphia (impaired handwriting, n=10), dyslexia (impaired word spelling and reading, n=20), and OWL LD (impaired syntax construction, n=6). The instruction was aimed at subword letter writing, word spelling, and syntax composing...
April 2017: Journal of Nature and Science
https://www.readbyqxmd.com/read/28670102/agreement-among-traditional-and-rti-based-definitions-of-reading-related-learning-disability-with-preschool-children
#6
Trelani F Milburn, Christopher J Lonigan, Darcey M Allan, Beth M Phillips
To investigate approaches for identifying young children who may be at risk for later reading-related learning disabilities, this study compared the use of four contemporary methods of indexing learning disability (LD) with older children (i.e., IQ-achievement discrepancy, low achievement, low growth, and dual-discrepancy) to determine risk status with a large sample of 1,011 preschoolers. These children were classified as at risk or not using each method across three early-literacy skills (i.e., language, phonological awareness, print knowledge) and at three levels of severity (i...
April 2017: Learning and Individual Differences
https://www.readbyqxmd.com/read/28668993/trauma-related-admissions-to-the-picu-at-chris-hani-baragwanath-academic-hospital-johannesburg
#7
Nirav Patel, I Khofi-Phiri, L R Mathiva, A Grieve, J Loveland, G D Nethathe
BACKGROUND: Paediatric trauma is a major cause of morbidity and mortality in low and middle income countries. Data from these regions are scant. We aimed to describe the demographic and injury profile, treatment modality and outcome of trauma admissions to the paediatric intensive care unit at Chris Hani Baragwanath Academic Hospital (CHBAH). METHODS: A retrospective record review of trauma cases admitted to the PICU at CHBAH from 2011 to 2013 was performed. RESULTS: One-fifth of admissions were due to trauma...
July 1, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28665684/maturation-of-the-infant-respiratory-microbiota-environmental-drivers-and-health-consequences-a-prospective-cohort-study
#8
Astrid A T M Bosch, Wouter A A de Steenhuijsen Piters, Marlies A van Houten, Mei Ling J N Chu, Giske Biesbroek, Jolanda Kool, Paula Pernet, Pieter-Kees C M de Groot, Marinus J C Eijkemans, Bart J F Keijser, Elisabeth A M Sanders, Debby Bogaert
RATIONALE: Perinatal and postnatal influences are presumed important drivers of the early-life respiratory microbiome composition. We hypothesized that the respiratory microbiome composition and development in infancy is affecting microbiome stability and thereby resilience against respiratory tract infections (RTIs) over time. OBJECTIVES: To investigate common environmental drivers, including birth mode, feeding type, antibiotic exposure and crowding conditions, in relation to respiratory tract microbiota maturation and stability, and consecutive risk of RTIs over the first year of life...
June 30, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28641707/analysis-of-transmitted-hiv-drug-resistance-from-2005-to-2015-in-victoria-australia-a-comparison-of-the-old-and-the-new
#9
Jodie D'Costa, Megan Gooey, Nicole Richards, Rizmina Sameer, Elaine Lee, Doris Chibo
Background: Baseline genotyping is part of standard-of-care treatment. It reveals that transmitted drug resistance (TDR) continues to be important for the management of HIV infection. Attention is typically focused on determining whether resistance to the protease inhibitors (PI) and reverse transcriptase inhibitors (RTI) occurs. However, the increasing use of integrase inhibitors (INIs) raises a concern that TDR to this class of antiretroviral drug may also occur. Methods: PI and RTI drug resistance genotyping was performed on blood samples collected between 2005 and 2015 from 772 treatment-naïve Victorian patients infected with HIV within the previous 12 months...
June 23, 2017: Sexual Health
https://www.readbyqxmd.com/read/28632037/construct-and-concurrent-validity-of-the-cambridge-neuropsychological-automated-tests-in-portuguese-older-adults-without-neuropsychiatric-diagnoses-and-with-alzheimer-s-disease-dementia
#10
Marta Matos Gonçalves, Maria Salomé Pinho, Mário R Simões
We aimed to analyze the construct and concurrent validity of the Rapid Visual Information Processing (RVP), Paired Associates Learning (PAL), Reaction Time (RTI), and Spatial Working Memory (SWM) tests from the Cambridge Neuropsychological Test Automated Battery (CANTAB®). Inclusion criteria were checked in a first session. The CANTAB and additional pencil-and-paper tests were administered within 1 week. The participants (aged 69-96 years) were 137 Portuguese adults without neuropsychiatric diagnoses and 37 adults with mild-to-moderate Alzheimer's disease dementia...
February 28, 2017: Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition
https://www.readbyqxmd.com/read/28625640/association-between-intensity-modulated-radiotherapy-and-survival-in-patients-with-stage-iii-non-small-cell-lung-cancer-treated-with-chemoradiotherapy
#11
Matthew Koshy, Renuka Malik, Michael Spiotto, Usama Mahmood, Chad G Rusthoven, David J Sher
PURPOSE: To determine the effect of radiotherapy (RT) technique on treatment compliance and overall survival (OS) in patients with stage III non-small lung cancer (NSCLC) treated with definitive chemoradiotherapy (CRT). METHODS AND MATERIALS: This study included patients with stage III NSCLC in the National Cancer Database treated between 2003 and 2011 with definitive CRT to 60-63 Gray (Gy). Radiation treatment interruption (RTI) was defined as a break of ≥4 days...
June 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/28611111/the-impact-of-interventions-to-improve-the-quality-of-prescribing-and-use-of-antibiotics-in-primary-care-patients-with-respiratory-tract-infections-a-systematic-review-protocol
#12
Nahara Anani Martínez-González, Samuel Coenen, Andreas Plate, Annelies Colliers, Thomas Rosemann, Oliver Senn, Stefan Neuner-Jehle
INTRODUCTION: Respiratory tract infections (RTIs) are the most common reason for primary care (PC) consultations and for antibiotic prescribing and use. The majority of RTIs have a viral aetiology however, and antibiotic consumption is ineffective and unnecessary. Inappropriate antibiotic use contributes greatly to antibiotic resistance (ABR) leading to complications, increased adverse events, reconsultations and costs. Improving antibiotic consumption is thus crucial to containing ABR, which has become an urgent priority worldwide...
June 13, 2017: BMJ Open
https://www.readbyqxmd.com/read/28610802/herbal-medicine-in-children-with-respiratory-tract-infection-systematic-review-and-meta-analysis
#13
REVIEW
Dennis Anheyer, Holger Cramer, Romy Lauche, Felix Joyonto Saha, Gustav Dobos
BACKGROUND: Herbal medicines are particularly regarded as an alternative or complement to conventional pharmaceuticals in the treatment and prevention of respiratory tract infections (RTI). OBJECTIVE: Therefore the purpose of this review was to identify evidence for herbal therapy in the treatment of RTI concerning effectiveness and safety. DATA SOURCES: Medline/PubMed, Scopus and the Cochrane Library were searched through 12 February 2015...
June 10, 2017: Academic Pediatrics
https://www.readbyqxmd.com/read/28588177/antibiotic-susceptibility-pattern-of-bacteria-isolated-from-various-specimens-of-patients-with-hematological-malignancy
#14
J Roy, D C Nag
Infection is a life threatening complication in patients with hematological malignancy. So, proper treatment of infection with suitable antibiotic is very important in these patients. The aim of this study was to determine the antibiotic susceptibility of bacteria isolated from various specimens of patients with hematological malignancy, so that, an appropriate regimen of empiric antibiotic treatment can be established for these patients. This observational study was done in the Department of Microbiology and Immunology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from March 2012 to August 2012...
April 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/28560198/exploring-measures-to-control-road-traffic-injuries-in-iran-key-informants-points-of-view
#15
Hedayat Salari, Seyed Abbas Motevalian, Mohammad Arab, Atefeh Esfandiari, Ali Akbari Sari
BACKGROUND: Injuries and fatalities from road traffic Injuries are global public health concerns, and a major problem in the Iran. This study aimed to explore strategies to control road traffic Injuries (RTI) in Iran. METHODS: We conducted a qualitative study to explore possible ways to reduce the occurrence of road traffic Injuries in Iran in 2016. Interviewees were purposively sampled from various sectors due to multidisciplinary nature of RTIs. Participants were mainly representatives from the police, Ministry of Road, Municipal, emergency services and Ministry of Health...
May 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28555484/spatial-analysis-of-the-regional-variation-of-reproductive-tract-infections-and-spousal-migration-correlates-in-nepal
#16
Derek C Johnson, Pema Lhaki, Charlotte Buehler Cherry, Mirjam-Colette Kempf, Eric Chamot, Sten H Vermund, Sadeep Shrestha
Nepal has a diverse geographic landscape that could potentially create clustered subpopulations with regional socio-cultures that could result in differential health outcomes. With an alarming rise in married male populations migrating for work, it is possible that these migrants are engaged in risky sexual behaviour, putting their wives at risk for infectious disease outcomes, including reproductive tract infections (RTI), when they return home. The prevalence of male migration varies by geographic region in Nepal and this variation could potentially contribute to different RTI rates...
May 30, 2017: Geospatial Health
https://www.readbyqxmd.com/read/28536303/implementing-a-fee-for-service-cervical-cancer-screening-and-treatment-program-in-cameroon-challenges-and-opportunities
#17
Geneva DeGregorio, Simon Manga, Edith Kiyang, Florence Manjuh, Leslie Bradford, Preetam Cholli, Richard Wamai, Rebecca Ogembo, Zacharie Sando, Yuxin Liu, Lisa Kennedy Sheldon, Kathleen Nulah, Thomas Welty, Edith Welty, Javier Gordon Ogembo
BACKGROUND: Cervical cancer screening is one of the most effective cancer prevention strategies, but most women in Africa have never been screened. In 2007, the Cameroon Baptist Convention Health Services, a large faith-based health care system in Cameroon, initiated the Women's Health Program (WHP) to address this disparity. The WHP provides fee-for-service cervical cancer screening using visual inspection with acetic acid enhanced by digital cervicography (VIA-DC), prioritizing care for women living with HIV/AIDS...
July 2017: Oncologist
https://www.readbyqxmd.com/read/28529012/the-epidemiology-and-hotspots-of-road-traffic-injuries-in-moshi-tanzania-an-observational-study
#18
Joseph M Reardon, Luciano Andrade, Julian Hertz, George Kiwango, Anneth Teu, Msafiri Pesambili, Deena El-Gabri, Michael Hocker, Mark Mvungi, João Ricardo N Vissoci, Catherine A Staton
Road traffic injuries (RTIs) continue to increase with the proliferation of motor vehicles, especially in low-income countries where safe road infrastructure is lacking. Knowing where and why RTIs occur would allow for increased safety and prevention planning. In this study, police records of 300 motor vehicle collisions which occurred between February 2013 and January 2014 in Moshi, Tanzania were reviewed. Analysis of variables including victim age, gender, type of collision, conditions, and use of safety equipment were analyzed...
July 2017: Injury
https://www.readbyqxmd.com/read/28518183/preclinical-evaluation-of-a-crown-splinted-custom-root-shaped-implant
#19
Elias D Kontogiorgos, Poorva Gharpure, Eberechukwu O Iheanacho, Christopher J Gonzales, Lynne A Opperman
OBJECTIVE: To test whether a Maryland bridge-type splint provides adequate stability for a custom root-shaped implant to osseointegrate in a manner substantially equivalent to that of a threaded implant. METHODS: Six beagle dogs were subjected to intraoral impressions and cone beam scans that were used to fabricate custom root-shaped implants (RTIs) and crowns. Premolars in the mandible (P4) and in the maxilla (P3) were extracted, and 24 RTIs were immediately placed in extraction sockets...
May 18, 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28500864/identification-of-human-bocavirus-type-4-in-a-child-asymptomatic-for-respiratory-tract-infection-and-acute-gastroenteritis-goi%C3%A3-nia-goi%C3%A3-s-brazil
#20
Teresinha Teixeira de Sousa, Tâmera Nunes Vieira Almeida, Fabíola Souza Fiaccadori, Menira Souza, Kareem Rady Badr, Divina das Dôres de Paula Cardoso
Human Bocavirus (HBoV) has been identified from feces and respiratory samples from cases of both acute gastroenteritis and respiratory illness as well as in asymptomatic individuals. The aim of this study was to detect and characterize HBoV from fecal samples collected from hospitalized children aged less than five years old with no symptoms of respiratory tract infection (RTI) or acute gastroenteritis (AGE). The study involved 119 children and one fecal sample was collected from each participant between 2014 and 2015...
May 10, 2017: Brazilian Journal of Infectious Diseases
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