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https://www.readbyqxmd.com/read/28922325/metacarpal-like-hand-classification-and-treatment-guidelines-for-microsurgical-reconstruction-with-toe-transplantation
#1
Fu-Chan Wei, Nidal F Al Deek, Yu-Te Lin, Chung-Chen Hsu, Cheng-Hung Lin
The metacarpal-like hand is a severe hand injury, never addressed before. It describes a hand that lost a significant degree of prehension through a wide array of amputations, involving all digits proximal to the functional length except in one finger or in two digits, including the thumb.Thumb condition can be used to differentiate between two types.In type I, the thumb is intact or amputated at/or distal to the interphalangeal joint (functional length); and therefore, the reconstruction is focused on fingers mainly...
September 14, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28922241/a-shift-in-the-orbit-immediate-endoscopic-reconstruction-after-transnasal-orbital-tumors-resection
#2
Giacomo Colletti, Alberto M Saibene, Federico Pessina, Marco Duvina, Fabiana Allevi, Giovanni Felisati, Federico Biglioli
Endoscopic endonasal resection of orbital lesions is a safe and common approach. Nevertheless, medial orbital wall defects following the procedure are not routinely addressed, potentially leading to diplopia and enophthalmos. In this article, the authors propose a new technique for purely endoscopic endonasal reconstruction of orbital wall defects following endoscopic endonasal resection of orbital lesions.The patient, a 43-year-old male, suffering from right exophthalmos and diplopia due to a venous malformation of the right orbit underwent endoscopic endonasal resection of the mass...
September 15, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28921755/homozygous-mutation-in-the-nphp3-gene-causing-foetal-nephronophthisis
#3
Uzma Abdullah, Muhammad Farooq, Ambrin Fatima, Wasima Tauseef, Yasra Sarwar, Mmh Nuri, Niels Tommerup, Shahid M Baig
We present a case of a foetal sonographic finding of hyper-echogenic kidneys, which led to a strategic series of genetic tests and identified a homozygous mutation (c.424C > T, p. R142*) in the NPHP3 gene. Our study provides a rare presentation of NPHP3-related ciliopathy and adds to the mutation spectrum of the gene, being the first one from Pakistani population. With a thorough literature review, it also advocates for molecular assessment of ciliopathies to improve risk estimate for future pregnancies, and identify predisposed asymptomatic carriers...
October 2017: Nephrology
https://www.readbyqxmd.com/read/28921609/biomarkers-for-equine-joint-injury-and-osteoarthritis
#4
REVIEW
C Wayne McIlwraith, Christopher E Kawcak, David D Frisbie, Christopher B Little, Peter D Clegg, Mandy J Peffers, Morten A Karsdal, Stina Ekman, Sheila Laverty, Richard A Slayden, Linda J Sandell, L Stefan Lohmander, Virginia B Kraus
We report the results of a symposium aimed at identifying validated biomarkers that can be used to complement clinical observations for diagnosis and prognosis of joint injury leading to equine osteoarthritis (OA). Biomarkers might also predict pre-fracture change that could lead to catastrophic bone failure in equine athletes. The workshop was attended by leading scientists in the fields of equine and human musculoskeletal biomarkers to enable cross-disciplinary exchange and improve knowledge in both. Detailed proceedings with strategic planning was written, added to, edited and referenced to develop this manuscript...
September 16, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28920624/directed-nucleophilic-addition-of-phenoxides-to-cyclopropenes
#5
Pavel Yamanushkin, Michael Lu-Diaz, Andrew Edwards, Nicolai A Aksenov, Marina Rubina, Michael Rubin
The alkali metal-templated addition of aryloxides across the double bond of non-conjugated cyclopropenes is described. High cis-selectivity is achieved through a directing effect of a strategically positioned carboxamide functionality.
September 18, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/28920521/implementing-evidence-based-smoking-cessation-treatment-in-psychosocial-care-units-caps-in-brazil
#6
João Mauricio Castaldelli-Maia, Nilson R da Silva, Marta Rd Campos, Helena F Moura, Gustavo Zabert, Beatriz M Champagne, Katherine E Kemper, J Taylor Hays
BACKGROUND: The prevalence of smoking among mental health and addiction (MHA) patients is 3 times higher than it is in the general population, yet this patient population has received little help to combat smoking. Considering this, psychosocial care centers (CAPS - Centros de Atenção Psicossocial) are strategic locations for integrating tobacco dependence treatment (TDT) into existing treatment activities. METHODS: Our team provided an 8-hour training package to the staff of CAPS that have not been providing specialized TDT for smokers...
September 1, 2017: International Journal of Social Psychiatry
https://www.readbyqxmd.com/read/28919844/practical-nutritional-recovery-strategies-for-elite-soccer-players-when-limited-time-separates-repeated-matches
#7
REVIEW
Mayur Krachna Ranchordas, Joel T Dawson, Mark Russell
Specific guidelines that aim to facilitate the recovery of soccer players from the demands of training and a congested fixture schedule are lacking; especially in relation to evidence-based nutritional recommendations. The importance of repeated high level performance and injury avoidance while addressing the challenges of fixture scheduling, travel to away venues, and training commitments requires a strategic and practically feasible method of implementing specific nutritional strategies. Here we present evidence-based guidelines regarding nutritional recovery strategies within the context of soccer...
2017: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/28917696/brain-mapping-in-multiple-sclerosis-lessons-learned-about-the-human-brain
#8
REVIEW
Massimo Filippi, Paolo Preziosa, Maria A Rocca
The application of structural and functional magnetic resonance imaging (MRI) techniques in patients with multiple sclerosis (MS) has certainly helped to improve our understanding of the mechanisms responsible for clinical disability and cognitive impairment in this condition. The numerous studies performed in MS patients have also provided many lessons on the structure-function relationships in the human brain, which could be applied to healthy subjects and to patients affected by other neurological conditions...
September 13, 2017: NeuroImage
https://www.readbyqxmd.com/read/28917129/residential-road-traffic-noise-and-general-mental-health-in-youth-the-role-of-noise-annoyance-neighborhood-restorative-quality-physical-activity-and-social-cohesion-as-potential-mediators
#9
Angel Dzhambov, Boris Tilov, Iana Markevych, Donka Dimitrova
Given the ubiquitous nature of both noise pollution and mental disorders, their alleged association has not escaped the spotlight of public health research. The effect of traffic noise on mental health is probably mediated by other factors, which have not been elucidated sufficiently. Herein, we aimed to disentangle the pathways linking road traffic noise to general mental health in Bulgarian youth, with a focus on several candidate mediators - noise annoyance, perceived restorative quality of the living environment, physical activity, and neighborhood social cohesion...
September 13, 2017: Environment International
https://www.readbyqxmd.com/read/28916512/strategic-programming-for-implantable-cardioverter-defibrillator-shock-reduction-following-the-greatest-happiness-principle
#10
EDITORIAL
Felix Krainski, Ulrika Birgersdotter-Green
No abstract text is available yet for this article.
September 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/28916511/failure-to-treat-life-threatening-ventricular-tachyarrhythmias-in-contemporary-implantable-cardioverter-defibrillators-implications-for-strategic-programming
#11
Anna Margrethe Thøgersen, Jacob Moesgaard Larsen, Jens Brock Johansen, Moeen Abedin, Charles D Swerdlow
BACKGROUND: In clinical trials, manufacturer-specific, strategic programming of implantable cardioverter-defibrillators (ICDs), including faster detection rates, reduces unnecessary therapy but permits therapy for ventricular tachycardia/ventricular fibrillation (VF). Present consensus recommends a generic rate threshold between 185 and 200 beats per minute, which exceeds the rate tested in clinical trials for some manufacturers. In a case series, we sought to determine the relationship between programmed parameters and failure of modern ICDs to treat VF...
September 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/28916496/designer-bacteria-as-intratumoural-enzyme-biofactories
#12
Panos Lehouritis, Glenn Hogan, Mark Tangney
Bacterial-directed enzyme prodrug therapy (BDEPT) is an emerging form of treatment for cancer. It is a biphasic variant of gene therapy in which a bacterium, armed with an enzyme that can convert an inert prodrug into a cytotoxic compound, induces tumour cell death following tumour-specific prodrug activation. BDEPT combines the innate ability of bacteria to selectively proliferate in tumours, with the capacity of prodrugs to undergo contained, compartmentalised conversion into active metabolites in vivo. Although BDEPT has undergone clinical testing, it has received limited clinical exposure, and has yet to achieve regulatory approval...
September 12, 2017: Advanced Drug Delivery Reviews
https://www.readbyqxmd.com/read/28916005/massachusetts-child-psychiatry-access-project-2-0-a-case-study-in-child-psychiatry-access-program-redesign
#13
REVIEW
Barry D Sarvet, Marcy Ravech, John H Straus
The Massachusetts Child Psychiatry Access Program is a statewide public mental health initiative designed to provide consultation, care navigation, and education to assist pediatric primary care providers in addressing mental health problems for children and families. To improve program performance, adapt to changes in the environment of pediatric primary care services, and ensure the program's long-term sustainability, program leadership in consultation with the Massachusetts Department of Mental Health embarked on a process of redesign...
October 2017: Child and Adolescent Psychiatric Clinics of North America
https://www.readbyqxmd.com/read/28915463/freshwater-vulnerability-under-high-end-climate-change-a-pan-european-assessment
#14
A G Koutroulis, L V Papadimitriou, M G Grillakis, I K Tsanis, K Wyser, R A Betts
As freshwater availability is crucial for securing a sustainable, lower‑carbon future, there is a critical connection between water management and climate policies. Under a rapidly changing climate, it is more important than ever to estimate the degree of future water security. This is a challenging task as it depends on many different variables: the degree of warming and its consequent effects on hydrological resources, the water demand by different sectors, and the possible ameliorations or deteriorations of the effects due to climate change adaptation and mitigation strategies...
September 12, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28915164/organizational-and-environmental-factors-influencing-hospital-community-orientation
#15
JʼAime C Jennings, Amy Y Landry, Larry R Hearld, Robert Weech-Maldonado, Scott W Snyder, Patricia A Patrician
BACKGROUND: Community orientation refers to hospitals' efforts to assess and meet the health needs of the local population. Variations in the number of community orientation-related activities offered by hospitals may be attributed to differences in organizational and environmental characteristics. Therefore, hospitals have to strategically respond to these internal and external constraints to improve community health. Understanding the facilitators and barriers of hospital community orientation is important to health care managers facing pressure from the external environment to meet the expectations of the community as well as Affordable Care Act guidelines...
September 15, 2017: Health Care Management Review
https://www.readbyqxmd.com/read/28914163/truth-or-punishment-secrecy-and-punishing-the-self
#16
Michael L Slepian, Brock Bastian
We live in a world that values justice; when a crime is committed, just punishment is expected to follow. Keeping one's misdeed secret therefore appears to be a strategic way to avoid (just) consequences. Yet, people may engage in self-punishment to right their own wrongs to balance their personal sense of justice. Thus, those who seek an escape from justice by keeping secrets may in fact end up serving that same justice on themselves (through self-punishment). Six studies demonstrate that thinking about secret (vs...
July 1, 2017: Personality & Social Psychology Bulletin
https://www.readbyqxmd.com/read/28913530/why-microfluidics-merits-and-trends-in-chemical-synthesis
#17
REVIEW
Yong Liu, Xingyu Jiang
The intrinsic limitations of conventional batch synthesis have hindered its applications in both solving classical problems and exploiting new frontiers. Microfluidic technology offers a new platform for chemical synthesis toward either molecules or materials, which has promoted the progress of diverse fields such as organic chemistry, materials science, and biomedicine. In this review, we focus on the improved performance of microreactors in handling various situations, and outline the trend of microfluidic synthesis (microsynthesis, μSyn) from simple microreactors to integrated microsystems...
September 15, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28912534/multisegmented-nanowires-a-step-towards-the-control-of-the-domain-wall-configuration
#18
E Berganza, M Jaafar, C Bran, J A Fernández-Roldán, O Chubykalo-Fesenko, M Vázquez, A Asenjo
Cylindrical nanowires synthesized by controlled electrodeposition constitute excellent strategic candidates to engineer magnetic domain configurations. In this work, multisegmented CoNi/Ni nanowires are synthesized for tailoring a periodic magnetic structure determined by the balance between magnetocrystalline and magnetostatic energies. High-resolution Transmission Electron Microscopy confirms the segmented growth and the sharp transition between layers. Although both CoNi and Ni segments have similar fcc cubic crystal symmetry, their magnetic configuration is quite different as experimentally revealed by Magnetic Force Microscopy (MFM) imaging...
September 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28911985/moving-forward-in-carcinogenicity-assessment-report-of-an-eurl-ecvam-estiv-workshop
#19
Raffaella Corvi, Federica Madia, Kathryn Z Guyton, Peter Kasper, Ruthann Rudel, Annamaria Colacci, Jos Kleinjans, Paul Jennings
There is an increased need to develop novel alternative approaches to the two-year rodent bioassay for the carcinogenicity assessment of substances where the rodent bioassay is still a basic requirement, as well as for those substances where animal use is banned or limited or where information gaps are identified within legislation. The current progress in this area was addressed in a EURL ECVAM- ESTIV workshop held in October 2016, in Juan les Pins. A number of initiatives were presented and discussed, including data-driven, technology-driven and pathway-driven approaches...
September 11, 2017: Toxicology in Vitro: An International Journal Published in Association with BIBRA
https://www.readbyqxmd.com/read/28911346/strategic-partnerships-towards-tuberculosis-elimination
#20
Justin T Denholm
No abstract text is available yet for this article.
October 1, 2017: International Journal of Tuberculosis and Lung Disease
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