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https://www.readbyqxmd.com/read/28935698/polysomnographic-phenotypes-and-their-cardiovascular-implications-in-obstructive-sleep-apnoea
#1
Andrey V Zinchuk, Sangchoon Jeon, Brian B Koo, Xiting Yan, Dawn M Bravata, Li Qin, Bernardo J Selim, Kingman P Strohl, Nancy S Redeker, John Concato, Henry K Yaggi
BACKGROUND: Obstructive sleep apnoea (OSA) is a heterogeneous disorder, and improved understanding of physiologic phenotypes and their clinical implications is needed. We aimed to determine whether routine polysomnographic data can be used to identify OSA phenotypes (clusters) and to assess the associations between the phenotypes and cardiovascular outcomes. METHODS: Cross-sectional and longitudinal analyses of a multisite, observational US Veteran (n=1247) cohort were performed...
September 21, 2017: Thorax
https://www.readbyqxmd.com/read/28929470/-sleep-apnoea-hypopnoea-syndrome-and-narcolepsy-description-of-a-series-of-hospital-patients
#2
M J Abenza-Abildua, V Lores-Gutierrez, M T Ramirez-Prieto, A Miralles-Martinez, M Prieto-Palacio, G Cordero-Martin, C Algarra-Lucas, A Gomez-Acena, C Jimeno-Montero, G Gutierrez-Cueto, E Macon-Liquete, B Bathal-Guede, J A Garcia-De Gregorio, A Perez-Villena, M L Herreros-Fernandez, F J Arpa-Gutierrez
INTRODUCTION: Sleep disorders are highly prevalent among the general population, although very few cases of sleep apnoea-hypopnoea syndrome (SAHS) have been reported in patients with narcolepsy. This study reviews the sleep disorders found in patients with narcolepsy, the prevalence of SAHS associated with these patients and their response to the different treatments. PATIENTS AND METHODS: We conducted an observation-based retrospective descriptive analysis of 25 patients diagnosed with narcolepsy, who were treated in our centre between October 2012 and December 2016...
October 1, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28901688/poly-glycerol-sebacate-combined-with-chondroitinase-abc-promotes-spinal-cord-repair-in-rats
#3
Qi Pan, Yan Guo, Fanyong Kong
This study was to investigate the feasibility of PGS combined with ChABC for repairing the transection of spinal cords (TSC) in rats. A thoracic 10 (T10) TSC model of rats was employed. The effects of PGS with ChABC on the morphology and histological structure of the spinal cords, Basso, Beattie, Bresnahan (BBB) scores, and the expression of GAP-43 and NF-200 were comparatively studied. The BBB scores indicated that all rats with TSC were paralyzed immediately after surgery and then recovered hind limb movement gradually, but did not fully recover until the end of week 12...
September 13, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28899286/restless-legs-syndrome-related-to-hemorrhage-of-a-thoracic-spinal-cord-cavernoma
#4
Malik Hamdaoui, Elisabeth Ruppert, Henri Comtet, Ulker Kilic-Huck, Valérie Wolff, Marc Bataillard, Patrice Bourgin
CONTEXT: Restless legs syndrome (RLS) is a common neurological disorder characterized by an irresistible urge to move the lower limbs often accompanied by unpleasant sensations in the legs, worsened at rest and in the evening. Symptoms are improved by movement. Its pathophysiology remains poorly understood. Lesion-related RLS has been reported, mainly in cases of stroke-related RLS involving the brainstem and lenticulostriate nuclei. Only few data of RLS in a context of spinal cord injury have been reported...
September 12, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28895457/polysomnography-in-pediatric-otolaryngology-if-not-obstructive-sleep-apnea-what-is-it
#5
Christine H Heubi, Jareen Meinzen-Derr, Sally R Shott, David F Smith, And Stacey L Ishman
Objective To determine common polysomnographic (PSG) diagnoses for children referred by otolaryngologists. Study Design Retrospective case series with chart review. Setting Single tertiary pediatric hospital (2010-2015). Subjects and Methods Review of the medical records of 1258 patients undergoing PSG by otolaryngology referral. Patients who underwent previous otolaryngologic surgery were excluded. Data distributions were evaluated using means with standard deviations for continuous variables and frequencies with percentages for categorical variables...
September 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28895021/k-band-doppler-radar-for-contact-less-overnight-sleep-marker-assessment-a-pilot-validation-study
#6
Rakesh Vasireddy, Corinne Roth, Johannes Mathis, Josef Goette, Marcel Jacomet, Andreas Vogt
An estimated 45 million persons in Europe are annually subjected to sleep-wake disorders. State-of-the-art polysomnography provides sophisticated insights into sleep (patho)physiology. A drawback of the method, however, is the obtrusive setting dependent on a clinical-based sleep laboratory with high operational costs. A contact-less prototype was developed to monitor limb movements and vital signs during sleep. A dual channel K-band Doppler radar transceiver captured limb movements and periodic chest wall motion due to respiration and heart activity...
September 11, 2017: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/28880052/effects-of-volleyball-plyometric-intervention-program-on-vertical-jumping-ability-in-male-volleyball-players
#7
Dariusz Mroczek, Krzysztof Maćkała, Adam Kawczynski, Edward Superlak, Paweł Chmura, Tomasz Seweryniak, Jan Chmura
BACKGROUND: This study aimed to investigate the effect of a 6-week plyometric exercise training program on the development of lower limb explosive power in terms of vertical jumping ability in university level volleyball players. The study involved 9 male volleyball players from the AWF Wroclaw University Sports Club, with a minimum of 5 years of training and competition experience. The program consisted of various bounds, hops, and jumps in vertical, horizontal, and mixed directions...
September 5, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28875581/european-guideline-for-the-diagnosis-and-treatment-of-insomnia
#8
REVIEW
Dieter Riemann, Chiara Baglioni, Claudio Bassetti, Bjørn Bjorvatn, Leja Dolenc Groselj, Jason G Ellis, Colin A Espie, Diego Garcia-Borreguero, Michaela Gjerstad, Marta Gonçalves, Elisabeth Hertenstein, Markus Jansson-Fröjmark, Poul J Jennum, Damien Leger, Christoph Nissen, Liborio Parrino, Tiina Paunio, Dirk Pevernagie, Johan Verbraecken, Hans-Günter Weeß, Adam Wichniak, Irina Zavalko, Erna S Arnardottir, Oana-Claudia Deleanu, Barbara Strazisar, Marielle Zoetmulder, Kai Spiegelhalder
This European guideline for the diagnosis and treatment of insomnia was developed by a task force of the European Sleep Research Society, with the aim of providing clinical recommendations for the management of adult patients with insomnia. The guideline is based on a systematic review of relevant meta-analyses published till June 2016. The target audience for this guideline includes all clinicians involved in the management of insomnia, and the target patient population includes adults with chronic insomnia disorder...
September 5, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28870053/-domestic-external-fixator-application-in-the-treatment-of-limb-deformities-7-289-cases-application-report
#9
S H Qin, B F Guo, X J Zheng, S F Jiao, H T Xia, A M Peng, Q Pan, J C Zang, Z J Wang
Objective: To discuss the clinical application and effects of domestic external fixator in the treatment of patients with malformations of limbs. Methods: A total of 7 289 patients with malformation of limbs who had been operated in Qin Sihe orthopedic surgery team from January 1989 to June 2016 were retrospective analyzed. The patients were treated with domestic external fixator, including 4 033 males and 3 256 females, aging from 2 to 82 years with a mean age of 23.4 years. There were 2 732 patients using Ilizarov external fixator, 4 713 patients using hybrid external fixator, 57 patients using monobrachial external fixator, 232 patients using Ilizarov external fixator and hybrid external fixator...
September 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/28863296/associations-of-prolonged-standing-with-musculoskeletal-symptoms-a-systematic-review-of-laboratory-studies
#10
REVIEW
Pieter Coenen, Sharon Parry, Lisa Willenberg, Joyce W Shi, Lorena Romero, Diana M Blackwood, Genevieve N Healy, David W Dunstan, Leon M Straker
While prolonged standing has shown to be detrimentally associated with musculoskeletal symptoms, exposure limits and underlying mechanisms are not well understood. We systematically reviewed evidence from laboratory studies on musculoskeletal symptom development during prolonged (≥20min) uninterrupted standing, quantified acute dose-response associations and described underlying mechanisms. Peer-reviewed articles were systematically searched for. Data from included articles were tabulated, and dose-response associations were statistically pooled...
August 24, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28859603/effects-of-constraint-induced-movement-therapy-for-lower-limbs-on-measurements-of-functional-mobility-and-postural-balance-in-subjects-with-stroke-a-randomized-controlled-trial
#11
Emília Márcia Gomes de Souza E Silva, Tatiana Souza Ribeiro, Tállyta Camyla Chaves da Silva, Mayara Fabiana Pereira Costa, Fabrícia Azevedo da Costa Cavalcanti, Ana Raquel Rodrigues Lindquist
Abstrato Background: Constraint-induced movement therapy (CIMT) is suggested to reduce functional asymmetry between the upper limbs after stroke. However, there are few studies about CIMT for lower limbs. OBJECTIVE: To examine the effects of CIMT for lower limbs on functional mobility and postural balance in subjects with stroke. METHODS: A 40-day follow-up, single-blind randomized controlled trial was performed with 38 subacute stroke patients (mean of 4.5 months post-stroke)...
August 31, 2017: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/28853423/daytime-sleepiness-more-than-just-obstructive-sleep-apnea-osa
#12
Luigi Ferini-Strambi, Marco Sforza, Mattia Poletti, Federica Giarrusso, Andrea Galbiati
Excessive Daytime Sleepiness (EDS) is a common condition with a significant impact on quality of life and general health. A mild form of sleepiness can be associated with reduced reactivity and modest distractibility symptoms, but more severe symptomatic forms are characterized by an overwhelming and uncontrollable need to sleep, causing sudden sleep attacks, amnesia and automatic behaviors. The prevalence in the general population is between 10 and 25%. Furthermore, EDS has been considered a core symptom of obstructive sleep apnea (OSA), as well as being the main symptom of primary hypersomnias such as narcolepsy types 1 and 2, and idiopathic hypersomnia...
August 28, 2017: La Medicina del Lavoro
https://www.readbyqxmd.com/read/28851789/brain-stimulation-for-arm-recovery-after-stroke-b-stars-protocol-for-a-randomised-controlled-trial-in-subacute-stroke-patients
#13
Eline C C van Lieshout, Johanna M A Visser-Meily, Sebastiaan F W Neggers, H Bart van der Worp, Rick M Dijkhuizen
INTRODUCTION: Many patients with stroke have moderate to severe long-term sensorimotor impairments, often including inability to execute movements of the affected arm or hand. Limited recovery from stroke may be partly caused by imbalanced interaction between the cerebral hemispheres, with reduced excitability of the ipsilesional motor cortex while excitability of the contralesional motor cortex is increased. Non-invasive brain stimulation with inhibitory repetitive transcranial magnetic stimulation (rTMS) of the contralesional hemisphere may aid in relieving a post-stroke interhemispheric excitability imbalance, which could improve functional recovery...
August 28, 2017: BMJ Open
https://www.readbyqxmd.com/read/28843638/local-vibration-inhibits-h-reflex-but-does-not-compromise-manual-dexterity-and-does-not-increase-tremor
#14
Francesco Budini, Luca Laudani, Sergio Bernardini, Andrea Macaluso
The present work aimed at investigating the effects of local vibration on upper limb postural and kinetic tremor, on manual dexterity and on spinal reflex excitability. Previous studies have demonstrated a decrease in spinal reflex excitability and in force fluctuations in the lower limb but an increase in force fluctuation in the upper limbs. As hand steadiness is of vital importance in many daily-based tasks, and local vibration may also be applied in movement disorders, we decided to further explore this phenomenon...
August 24, 2017: Human Movement Science
https://www.readbyqxmd.com/read/28837991/the-role-of-iron-in-pediatric-restless-legs-syndrome-and-periodic-limb-movements-in-sleep
#15
Tiffany Munzer, Barbara Felt
No abstract text is available yet for this article.
August 2017: Seminars in Neurology
https://www.readbyqxmd.com/read/28836845/repeatability-of-gait-pattern-variables-measured-by-use-of-extremity-mounted-inertial-measurement-units-in-nonlame-horses-during-trotting
#16
Antonio M Cruz, Ugo E Maninchedda, Dominik Burger, Sabine Wanda, Beatriz Vidondo
OBJECTIVE To determine repeatability of gait variables measured by use of extremity-mounted inertial measurement units (IMUs) in nonlame horses during trotting under controlled conditions of treadmill exercise. ANIMALS 10 horses. PROCEDURES Six IMUs were strapped to the metacarpal, metatarsal, and distal tibial regions of each horse. Data were collected in a standardized manner (3 measurements/d on 3 d/wk over a 3-week period) while each horse was trotted on a treadmill. Every measurement consisted of a minimum of 20 strides from which a minimum of 10 strides was selected for analysis...
September 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28831753/pharmacological-management-of-restless-legs-syndrome-and-periodic-limb-movement-disorder-in-children
#17
Geoffrey Rulong, Thomas Dye, Narong Simakajornboon
Restless legs syndrome (RLS) and periodic limb movement disorder (PLMD) are under-recognized sleep disorders in children and adolescents. Several recent epidemiological studies have shown that RLS and PLMD are common in the pediatric population, and if left untreated, may lead to cardiovascular and neurocognitive consequences. Therefore, early diagnosis and intervention may help preventing long-term consequences. The management of RLS and PLMD in children involves both non-pharmacologic and pharmacologic approaches...
August 22, 2017: Paediatric Drugs
https://www.readbyqxmd.com/read/28822709/the-influence-of-antidepressants-on-restless-legs-syndrome-and-periodic-limb-movements-a-systematic-review
#18
REVIEW
Bhanu Prakash Kolla, Meghna P Mansukhani, J Michael Bostwick
Restless legs syndrome is commonly co-morbid with medical conditions that are treated with antidepressant medications, such as depression, anxiety, fibromyalgia, and chronic insomnia disorder. Evidence from case reports and cross-sectional studies suggests that antidepressants may induce or worsen restless legs syndrome and increase periodic limb movements. We undertook a systematic review of the literature to identify and collate all prospective studies that measured restless legs syndrome symptoms and/or periodic limb movements following the introduction of an antidepressant...
June 15, 2017: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/28822017/validation-of-a-non-contact-screening-device-for-the-combination-of-sleep-disordered-breathing-and-periodic-limb-movements-in-sleep
#19
Gerhard Weinreich, Sarah Terjung, Yi Wang, Stefanie Werther, Alberto Zaffaroni, Helmut Teschler
PURPOSE: Recent studies found that the non-contact screening device SleepMinder (ResMed Sensor Technologies, Dublin, Ireland) detects sleep-disordered breathing (SDB) with high diagnostic accuracy in cohorts suspected of this disorder. However, it was reported that in patients with periodic limb movement in sleep (PLMS), this non-contact device overestimates the apnea-hypopnea index (AHI). We aimed to overcome this limitation by introducing the novel sleep disorder index (SDI) which is sum of the AHI and the period limb movement index (PLMI)...
August 18, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28809628/-the-effect-of-activation-of-the-shoulder-girdle-muscles-on-functional-outcomes-of-rehabilitation-in-patients-with-surgically-treated-distal-radius-fractures
#20
V Jančíková, J Opavský, P Dráč, A Krobot, I Čižmář
PURPOSE OF THE STUDY The aim of the study was to assess the functional outcomes of rehabilitation in patients with surgically treated distal radius fractures in the early postoperative period. We compared the functional outcomes of patients undergoing standard rehabilitation with the group of patients whose postoperative rehabilitation was extended with shoulder girdle exercises of the affected upper limb while the wrist was immobilized. Several indices and variables were used for the assessment of the functional therapeutic outcomes of the affected wrist...
2017: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
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