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Periodic limbs movement

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https://www.readbyqxmd.com/read/29773349/robot-assisted-training-using-hybrid-assistive-limb%C3%A2-for-cerebral-palsy
#1
Mayumi Matsuda, Nobuaki Iwasaki, Yuki Mataki, Hirotaka Mutsuzaki, Kenichi Yoshikawa, Kazushi Takahashi, Keiko Enomoto, Kumiko Sano, Aoi Kubota, Tomohiro Nakayama, Junko Nakayama, Haruka Ohguro, Masafumi Mizukami, Kazuhide Tomita
PURPOSE: The Hybrid Assistive Limb® (HAL®, CYBERDYNE) is a wearable robot that provides assistance to a patient while they are walking, standing, and performing leg movements based on the wearer's intended movement. The effect of robot-assisted training using HAL® for cerebral palsy (CP) is unknown. Therefore, we assessed the effect of robot-assisted training using HAL® on patients with CP, and compared walking and gross motor abilities between pre-intervention and post-intervention...
May 14, 2018: Brain & Development
https://www.readbyqxmd.com/read/29773209/prevalence-and-risk-factors-of-type-2-diabetes-in-insomnia-sufferers-a-study-on-1311-individuals-referred-for-sleep-examinations
#2
Matthieu Hein, Jean-Pol Lanquart, Gwénolé Loas, Philippe Hubain, Paul Linkowski
BACKGROUND: Several studies have investigated the particular relationship between insomnia and type 2 diabetes. However, few studies have investigated the prevalence and risk factors for type 2 diabetes in insomnia sufferers. The aim of this study was to examine the prevalence and risk factors of type 2 diabetes in a large sample of insomnia sufferers. METHODS: Data from 1311 insomnia sufferers recruited from the research database of the Erasme Hospital sleep laboratory were analyzed...
June 2018: Sleep Medicine
https://www.readbyqxmd.com/read/29766677/sleeping-child-neuroendocrine-cell-hyperplasia-of-infancy-and-polysomnography
#3
Deborah R Liptzin, Stephen M M Hawkins, Brandie D Wagner, Robin R Deterding
OBJECTIVES: Neuroendocrine cell hyperplasia of infancy (NEHI) is a children's interstitial and diffuse lung disease of unknown etiology that presents in infancy with characteristic findings of tachypnea, retractions, crackles, and hypoxemia. At the present, the mainstay of treatment is oxygen supplementation to normalize oxygen saturations and decrease work of breathing. There are characteristic pulmonary function, radiographic, and histologic findings, but polysomnography (PSG) data has not been reported...
May 15, 2018: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29764215/myotonic-dystrophytype-1-report-of-non-24-h-sleep-wake-disorder-with-excessive-daytime-sleepiness
#4
Lucio Huebra Pimentel Filho, Ana Carolina Dias Gomes, Bruno Gonçalves, Sergio Tufik, Fernando Morgadinho Coelho
Myotonic dystrophy (MD) is a neuromuscular disease with myotonia, progressive weakness, and involvement of CNS, heart, and gastrointestinal system. Excessive daytime sleepiness (EDS) in myotonic dystrophy type 1 (MD1) is related to sleep breathing diseases, restless leg syndrome, periodic limb movements during sleep and narcoleptic-like phenotype. However, authors highlight a central dysfunction of sleep regulation. We describe a 26-year-old, female, MD1 patient with EDS. Sleep diary/actigraphy evidenced two different circadian periods with values of 1442 and 1522 min...
May 15, 2018: Chronobiology International
https://www.readbyqxmd.com/read/29755399/leg-prosthesis-with-somatosensory-feedback-reduces-phantom-limb-pain-and-increases-functionality
#5
Caroline Dietrich, Sandra Nehrdich, Sandra Seifert, Kathrin R Blume, Wolfgang H R Miltner, Gunther O Hofmann, Thomas Weiss
Phantom limb pain (PLP) develops in most patients with lower limb amputation. Changes in the peripheral and central nervous system (CNS) are hypothesized to contribute to PLP. Based on ideas to modify neural reorganization within the CNS, the aim of the study was to test, whether prostheses with somatosensory feedback might help to reduce PLP, and increase the functionality of movement with a prosthesis. We therefore equipped the prostheses of 14 lower leg amputees with a simple to use feedback system that provides electrocutaneous feedback to patients' thigh whenever the foot and toes of the prosthesis touch the ground...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29749917/a-novel-neural-prosthesis-providing-long-term-electrocorticography-recording-and-cortical-stimulation-for-epilepsy-and-brain-computer-interface
#6
Pantaleo Romanelli, Marco Piangerelli, David Ratel, Christophe Gaude, Thomas Costecalde, Cosimo Puttilli, Mauro Picciafuoco, Alim Benabid, Napoleon Torres
OBJECTIVE Wireless technology is a novel tool for the transmission of cortical signals. Wireless electrocorticography (ECoG) aims to improve the safety and diagnostic gain of procedures requiring invasive localization of seizure foci and also to provide long-term recording of brain activity for brain-computer interfaces (BCIs). However, no wireless devices aimed at these clinical applications are currently available. The authors present the application of a fully implantable and externally rechargeable neural prosthesis providing wireless ECoG recording and direct cortical stimulation (DCS)...
May 11, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29740377/muscle-activation-during-grasping-with-and-without-motor-imagery-in-healthy-volunteers-and-patients-after-stroke-or-with-parkinson-s-disease
#7
Manuela Kobelt, Brigitte Wirth, Corina Schuster-Amft
Introduction: The present study assessed whether motor imagery (MI) produces electromyographic activation in specific muscles of the upper limb during a hand grasping and arm-lifting task in healthy volunteers, patients after stroke, or with Parkinson's disease. Electromyographic (EMG) activation was compared under three conditions: MI, physical execution (PE), and rest. The task is clinically relevant unilateral executed movement using open muscle chains. Methods: In a cross-sectional study EMG activation was measured in four muscles: M...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29731671/the-level-of-observed-physical-movement-accompanying-periodic-limb-movements-measured-in-a-clinical-sleep-population
#8
Robert G Hooper
Study objectives: Periodic limb movements (PLMs) are routinely measured during polysomnogram (PSG) testing. During the early years of sleep testing, physical movements were identified and over time, consensus ultimately led to the current definitions of movement disorders including criteria used to measure PLMs on PSG testing. There has been considerable debate about the clinical importance of the PLMs measured during PSG testing. Over the last decade, the author has observed significant variations in the actual visible physical movements observed with a PLM event...
2018: Nature and Science of Sleep
https://www.readbyqxmd.com/read/29720720/gamma-aminobutyric-acid-gaba-receptors-genes-polymorphisms-and-risk-for-restless-legs-syndrome
#9
Félix Javier Jiménez-Jiménez, Gara Esguevillas, Hortensia Alonso-Navarro, Martín Zurdo, Laura Turpín-Fenoll, Jorge Millán-Pascual, Teresa Adeva-Bartolomé, Esther Cubo, Francisco Navacerrada, Gemma Amo, Ana Rojo-Sebastián, Lluisa Rubio, Mónica Díez-Fairén, Pau Pastor, Marisol Calleja, José Francisco Plaza-Nieto, Belén Pilo-de-la-Fuente, Margarita Arroyo-Solera, Esteban García-Albea, José A G Agúndez, Elena García-Martín
The possible role of gammaaminobutyric acid (GABA) in the pathophysiology of restless legs syndrome (RLS) is suggested by the symptomatic improvement achieved with GABAergic drugs. Thalamic GABA levels have shown positive correlation with periodic limb movements indices and with RLS severity. We tried to investigate the possible association between the most common single nucleotide polymorphisms (SNPs) in the GABA receptors (GABR) genes rho1, 2, and 3 (GABRR1, GABRR2, GABRR3), alpha4 (GABRA4), epsilon (GABRE), and theta (GABRQ) with the risk of developing RLS...
May 3, 2018: Pharmacogenomics Journal
https://www.readbyqxmd.com/read/29719424/heart-rate-phenotypes-and-clinical-correlates-in-a-large-cohort-of-adults-without-sleep-apnea
#10
Zhaoyang Huang, Balaji Goparaju, He Chen, Matt T Bianchi
Background: Normal sleep is associated with typical physiological changes in both the central and autonomic nervous systems. In particular, nocturnal blood pressure dipping has emerged as a strong marker of normal sleep physiology, whereas the absence of dipping or reverse dipping has been associated with cardiovascular risk. However, nocturnal blood pressure is not measured commonly in clinical practice. Heart rate (HR) dipping in sleep may be a similar important marker and is measured routinely in at-home and in-laboratory sleep testing...
2018: Nature and Science of Sleep
https://www.readbyqxmd.com/read/29718809/optogenetic-surface-stimulation-of-the-rat-cervical-spinal-cord
#11
Sarah E Mondello, Michael D Sunshine, Amanda E Fischedick, Sam J Dreyer, Gregory D Horwitz, Polina Anikeeva, Philip J Horner, Chet T Moritz
Electrical intraspinal microstimulation (ISMS) at various sites along the cervical spinal cord permits forelimb muscle activation, elicits complex limb movements, and may enhance functional recovery after spinal cord injury (SCI). Here, we explore optogenetic spinal stimulation (OSS) as a less invasive and cell-type specific alternative to ISMS. To map forelimb muscle activation by OSS in rats, adeno-associated viruses (AAV) carrying the blue-light sensitive ion channels channelrhodopsin-2 (ChR2) and Chronos were injected into the cervical spinal cord at different depths and volumes...
May 2, 2018: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29706760/brain-motor-control-assessment-post-early-intensive-hand-rehabilitation-after-spinal-cord-injury
#12
Maryam Zoghi, Mary Galea
Background: The Brain Motor Control Assessment (BMCA) is a surface electromyography (sEMG)-based measure of motor output from the central nervous system during a variety of reflex and voluntary motor tasks. Objective: The aim of this study was to assess the pattern of voluntary movements in patients with spinal cord injury (SCI) to investigate whether BMCA could add more resolution to clinical assessments and the recovery path of these patients. Method: Ten participants were recruited from the Royal Talbot Rehabilitation Centre as part of a multicenter randomized controlled trial...
2018: Topics in Spinal Cord Injury Rehabilitation
https://www.readbyqxmd.com/read/29686256/passive-limb-movement-intervals-results-in-repeated-hyperemic-responses-in-those-with-paraplegia
#13
Keith J Burns, Brandon S Pollock, Jon Stavres, Martin Kilbane, Amber Brochetti, John McDaniel
STUDY DESIGN: Repeated measures. OBJECTIVES: Reports suggest passive limb movement (PLM) could be used as a therapy to increase blood flow and tissue perfusion in the paralyzed lower limbs of those with spinal cord injuries. However, the hyperemic response to PLM appears to be transient, lasting only 30-45 s despite continued limb movement. The purpose of this investigation was to determine whether the hyperemic response is repeatable across multiple short bouts of passive limb movement...
April 23, 2018: Spinal Cord
https://www.readbyqxmd.com/read/29670152/improvement-of-cerebellar-ataxic-gait-by-injecting-cbln1-into-the-cerebellum-of-cbln1-null-mice
#14
Eri Takeuchi, Aya Ito-Ishida, Michisuke Yuzaki, Dai Yanagihara
Patients and rodents with cerebellar damage display ataxic gaits characterized by impaired coordination of limb movements. Here, gait ataxia in mice with a null mutation of the gene for the cerebellin 1 precursor protein (cbln1-null mice) was investigated by kinematic analysis of hindlimb movements during locomotion. The Cbln1 protein is predominately produced and secreted from cerebellar granule cells. The cerebellum of cbln1-null mice is characterized by an 80% reduction in the number of parallel fiber-Purkinje cell synapses compared with wild-type mice...
April 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29668694/the-efficacy-and-tolerability-of-rotigotine-on-patients-with-periodic-limb-movement-in-sleep-a-systematic-review-and-meta-analysis
#15
Meng-Ni Wu, Ping-Tao Tseng, Tien-Yu Chen, Yen-Wen Chen, Li-Min Liou, Pao-Yen Lin, Chung-Yao Hsu
OBJECTIVE: There is still no consensus on the treatment for periodic limb movement in sleep (PLMS). This study aimed to determine the efficacy and tolerability of rotigotine in patients suffering from PLMS. METHODS: Publications listed in PubMed, ScienceDirect, The Cochrane Library, and ClinicalTrials.gov were reviewed to assess the efficacy of rotigotine on PLMS. Analyses of PLMS frequency before and after rotigotine treatments (pre- and post-intervention studies) and PLMS frequency between placebo and rotigotine treatments (placebo-controlled trial studies) were included in our study...
2018: PloS One
https://www.readbyqxmd.com/read/29644903/patients-with-chronic-rhinosinusitis-and-obstructive-sleep-apnea-have-increased-paroxysmal-limb-movement
#16
Mahboobeh Mahdavinia, Jessica W Hui, Mohamed Zitun, Alejandra Lastra, James J Herdegen, Christopher D Codispoti, Rafsa J Khan, Phillip S LoSavio, Pete S Batra
BACKGROUND: Patients with chronic rhinosinusitis (CRS) frequently experience sleep disruption and are at a higher than normal risk for obstructive sleep apnea (OSA). The purpose of this study was to determine how CRS affects polysomnography findings and sleep-related breathing in OSA. METHODS: A cohort study was performed that included 107 adult patients with CRS and comorbid OSA (CRS+OSA group) and 137 patients with OSA and without CRS as the control group. An electronic medical records database was used to identify eligible subjects...
March 2018: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/29643080/periodic-limb-movements-during-sleep-in-stroke-tia-prevalence-course-and-cardiovascular-burden
#17
Mauro Manconi, Francesco Fanfulla, Raffaele Ferri, Silvia Miano, Josè Haba-Rubio, Raphael Heinzer, Thomas Horvath, Paola Proserpio, Peter Young, Giorgio Moschovitis, Andrea Seiler, Carlo Cereda, Lino Nobili, Roland Wiest, Sebastian R Ott, Claudio L Bassetti
OBJECTIVE: To define the prevalence, time course, and associated factors of periodic limb movements during sleep (PLMS) in patients with ischemic stroke or TIA. METHODS: Patients enrolled in the prospective Sleep-Disordered Breathing in Transient Ischemia Attack (TIA)/Ischemic Stroke and Continuous Positive Airway Pressure (CPAP) Treatment Efficacy (SAS-CARE) study underwent a double polysomnographic investigation in the acute and chronic phases after stroke/TIA, together with a MRI brain scan and a 24-hour blood pressure evaluation...
May 8, 2018: Neurology
https://www.readbyqxmd.com/read/29609717/sleep-disorders-and-their-management-in-children-with-ehlers-danlos-syndrome-referred-to-sleep-clinics
#18
Keren Armoni Domany, Sumalee Hantragool, David F Smith, Yuanfang Xu, Monir Hossain, Narong Simakajornboon
STUDY OBJECTIVES: The nature of sleep disorders in children with Ehlers-Danlos syndrome (EDS) is unknown. We aimed to describe the type, the management, and the short-term outcome of sleep disorders in children with EDS referred to sleep clinics. METHODS: This is a retrospective review of medical records and polysomnography tests of children with EDS younger than 18 years who were referred to the sleep clinic. Demographic information and medical history were collected, and polysomnography tests were reviewed...
March 30, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29609709/integrating-the-divided-nasal-cannula-into-routine-polysomnography-to-assess-nasal-cycle-feasibility-and-effect-on-outcomes
#19
Marcelo Scapuccin, Logan Schneider, Nur Rashid, Soroush Zaghi, Talita Rosa, Yung-An Tsuo, Stanley Liu, Paulo Lazarini, Robson Capasso, Chad Ruoff
STUDY OBJECTIVES: Patients suspected to have sleep-disordered breathing underwent an overnight polysomnography using a divided nasal cannula to gain additional information about the nasal cycle during sleep. METHODS: This was a prospective, observational cohort study replacing the undivided nasal cannula with a divided nasal cannula during routine polysomnography (n = 28). RESULTS: Integration of the divided nasal cannula pressure transducer system into routine polysomnography was easy and affordable...
March 30, 2018: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/29590559/decreased-prefrontal-oxygenation-elicited-by-stimulation-of-limb-mechanosensitive-afferents-during-cycling-exercise
#20
Ryota Asahara, Kanji Matsukawa
Our laboratory reported using near-infrared spectroscopy that feedback from limb mechanoafferents may decrease prefrontal oxygenated-hemoglobin concentration (Oxy-Hb) during the late period of voluntary and passive cycling. To test the hypothesis that the decreased Oxy-Hb of the prefrontal cortex would be augmented depending on the extent of limb mechanoafferent input, the prefrontal Oxy-Hb response was measured during motor-driven one- and two-legged passive cycling for 1 min at various revolutions of pedal movement in 19 subjects...
March 28, 2018: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
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