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https://www.readbyqxmd.com/read/29667094/worldwide-experience-with-erosion-of-the-magnetic-sphincter-augmentation-device
#1
Evan T Alicuben, Reginald C W Bell, Blair A Jobe, F P Buckley, C Daniel Smith, Casey J Graybeal, John C Lipham
BACKGROUND: The magnetic sphincter augmentation device continues to become a more common antireflux surgical option with low complication rates. Erosion into the esophagus is an important complication to recognize and is reported to occur at very low incidences (0.1-0.15%). Characterization of this complication remains limited. We aim to describe the worldwide experience with erosion of the magnetic sphincter augmentation device including presentation, techniques for removal, and possible risk factors...
April 17, 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29606884/proton-pump-inhibitor-refractory-gastroesophageal-reflux-disease-challenges-and-solutions
#2
REVIEW
Joseph Mermelstein, Alanna Chait Mermelstein, Maxwell M Chait
A significant percentage of patients with gastroesophageal reflux disease (GERD) will not respond to proton pump inhibitor (PPI) therapy. The causes of PPI-refractory GERD are numerous and diverse, and include adherence, persistent acid, functional disorders, nonacid reflux, and PPI bioavailability. The evaluation should start with a symptom assessment and may progress to imaging, endoscopy, and monitoring of esophageal pH, impedance, and bilirubin. There are a variety of pharmacologic and procedural interventions that should be selected based on the underlying mechanism of PPI failure...
2018: Clinical and Experimental Gastroenterology
https://www.readbyqxmd.com/read/29572021/a-novel-tissue-treatment-to-reduce-mineralization-of-bovine-pericardial-heart-valves
#3
Bart Meuris, Herbert De Praetere, Marina Strasly, Piero Trabucco, John C Lai, Peter Verbrugghe, Paul Herijgers
OBJECTIVE: With the increasing use of bioprostheses worldwide, continuous efforts have been made to improve tissue durability. We introduce a new treatment for bovine pericardium combining octanediol-ethanol based phospholipid removal with taurine-based glutaraldehyde neutralization and storage in an aldehyde-free solution (FREE). METHODS: Treated tissues were evaluated by mechanical and biochemical characterization, phospholipid content, aldehyde levels, cell cultures on pericardial samples (L929 fibroblasts and human umbilical vein endothelial cells), rat subcutaneous implantations, and long-term juvenile sheep mitral valve implantations (n = 3)...
February 21, 2018: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29509533/new-minimally-invasive-endoscopic-and-surgical-therapies-for-gastroesophageal-reflux-disease-gerd
#4
Alexandru Eugen Nicolau, Adrian Lobonţiu, Silviu Constantinoiu
GERD has become one of the most frequent pathology of the upper GI tract. It is a spectrum disease and is a progressive disease as well. Serious and severe complications are possible. The mainstream therapy in most of the patients is the medical therapy with PPI's. The most severe cases with an impaired LES (Lower Esophageal Sphincter) function as well as important anatomical disruptions are of surgical indication, the gold standard being laparoscopic fundoplication, an elective therapy with long term follow up outcomes at the expense of de novo symptoms associated with fundoplications in general...
January 2018: Chirurgia
https://www.readbyqxmd.com/read/29471155/early-results-of-magnetic-sphincter-augmentation-versus-fundoplication-for-gastroesophageal-reflux-disease-systematic-review-and-meta-analysis
#5
REVIEW
Alberto Aiolfi, Emanuele Asti, Daniele Bernardi, Gianluca Bonitta, Emanuele Rausa, Stefano Siboni, Luigi Bonavina
BACKGROUND: Laparoscopic Nissen and Toupet fundoplication (LF) are currently considered gold-standard surgical treatment for Gastroesophageal Reflux Disease (GERD). Magnetic Sphincter Augmentation (MSA) is an innovative surgical procedure that has been showed to be effective to control GERD symptoms and to reduce esophageal acid exposure. The aim of this systematic review and meta-analysis was to compare early outcomes of LF and MSA. MATERIALS AND METHODS: PubMed, MEDLINE, Embase, and Cochrane databases were consulted matching the terms "Gastroesophageal reflux or heartburn", "LINX or magnetic sphincter augmentation" and "fundoplication"...
February 20, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29371601/streamlined-asymmetric-%C3%AE-difunctionalization-of-ynones
#6
Siyu Peng, Zhaofeng Wang, Linxing Zhang, Xinhao Zhang, Yong Huang
Ynones are a unique class of structural motifs that show remarkable chemical versatility. Chiral ynones, particularly those possessing an α-stereogenic center, are highly attractive templates for structural diversification. So far, only very limited examples have been reported for asymmetric α-functionalization of ynones. Asymmetric double α-functionalization of ynones remains elusive. Here we describe a streamlined strategy for asymmetric α-difunctionalization of ynones. We developed a gold-catalyzed multicomponent condensation reaction from a simple ynone, an amine, and an electrophilic alkynylating reagent to generate a 1,2-dialkynyl enamine, a key stable and isolable intermediate...
January 25, 2018: Nature Communications
https://www.readbyqxmd.com/read/28936790/favorable-results-from-a-prospective-evaluation-of-200-patients-with-large-hiatal-hernias-undergoing-linx-magnetic-sphincter-augmentation
#7
F P Buckley, Reginald C W Bell, Kate Freeman, Stephanie Doggett, Rachel Heidrick
INTRODUCTION: Magnetic sphincter augmentation (MSA) of the lower esophageal sphincter restores the antireflux barrier in patients with hiatal hernias ≤3 cm. We performed a prospective study in patients undergoing MSA with the LINX device during repair of paraesophageal and hernias over 3 cm axial component. METHODS AND PROCEDURES: Multicenter, prospective study of consecutive patients treated with MSA at the time of repair of hiatal hernias >3 cm. RESULTS: 200 patients (110 female) were treated between March 2014 and February 2017 via laparoscopic hernia repair and MSA...
April 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/28842765/sages-technology-and-value-assessment-committee-tavac-safety-and-effectiveness-analysis-linx-%C3%A2-reflux-management-system
#8
Dana A Telem, Andrew S Wright, Paresh C Shah, Matthew M Hutter
No abstract text is available yet for this article.
October 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28671205/pbtio-3-based-perovskite-ferroelectric-and-multiferroic-thin-films
#9
Yilin Wang, Hanqing Zhao, Linxing Zhang, Jun Chen, Xianran Xing
Ferroelectric thin films, especially PbTiO3 -based perovskite thin films which possess robust spontaneous electrical polarization, are widely investigated and applied in various devices. With the advances in synthesis, characterization and calculation techniques, diverse phenomena and properties are uncovered in ferroelectric thin films. Herein some typical PbTiO3 -based perovskite thin films through composition control are introduced, which gives more choices with various ferroelectric or other properties...
July 21, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28623447/new-approaches-to-gastroesophageal-reflux-disease
#10
William Kethman, Mary Hawn
BACKGROUND: Gastroesophageal reflux disease (GERD) is the most common gastrointestinal disorder of the esophagus. It is a chronic, progressive disorder that presents most typically with heartburn and regurgitation and atypically with chest pain, dysphagia, chronic cough, globus, or sore throat. The mainstay for diagnosis and characterization of the disorder is esophagoduodenoscopy (EGD), high-resolution esophageal manometry, and symptom-associated ambulatory esophageal pH impedance monitoring...
September 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28581727/density-functional-theory-study-of-the-reaction-between-d-0-tungsten-alkylidyne-complexes-and-h-2-o-addition-versus-hydrolysis
#11
Ping Chen, Linxing Zhang, Zi-Ling Xue, Yun-Dong Wu, Xinhao Zhang
The reactions of early-transition-metal complexes with H2 O have been investigated. An understanding of these elementary steps promotes the design of precursors for the preparation of metal oxide materials or supported heterogeneous catalysts. Density functional theory (DFT) calculations have been conducted to investigate two elementary steps of the reactions between tungsten alkylidyne complexes and H2 O, i.e., the addition of H2 O to the W≡C bond and ligand hydrolysis. Four tungsten alkylidyne complexes, W(≡CSiMe3 )(CH2 SiMe3 )3 (A-1), W(≡CSiMe3 )(CH2 t Bu)3 (B-1), W(≡Ct Bu)(CH2 t Bu)3 (C-1), and W(≡Ct Bu)(Ot Bu)3 (D-1), have been compared...
June 19, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28488920/two-stage-explantation-of-a-magnetic-lower-esophageal-sphincter-augmentation-device-due-to-esophageal-erosion
#12
Abhishek D Parmar, Robert A Tessler, Howard Y Chang, Jonathan D Svahn
INTRODUCTION: Implanting a magnetic lower esophageal sphincter augmentation device (LINX, Torax Medical) has become an increasingly common option in the surgical management of gastroesophageal reflux disease. As the enthusiasm for placing this device increases, experience in the management of device-related complications-including erosion-is necessary. METHODS: We report a staged approach to LINX removal in a 64-year-old female with symptoms of odynophagia secondary to partial erosion of a LINX device into the esophagus...
August 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28428706/gastroesophageal-reflux-disease-and-morbid-obesity-to-sleeve-or-not-to-sleeve
#13
EDITORIAL
Fabrizio Rebecchi, Marco E Allaix, Marco G Patti, Francisco Schlottmann, Mario Morino
Laparoscopic sleeve gastrectomy (LSG) has reached wide popularity during the last 15 years, due to the limited morbidity and mortality rates, and the very good weight loss results and effects on comorbid conditions. However, there are concerns regarding the effects of LSG on gastroesophageal reflux disease (GERD). The interpretation of the current evidence is challenged by the fact that the LSG technique is not standardized, and most studies investigate the presence of GERD by assessing symptoms and the use of acid reducing medications only...
April 7, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28420936/linx-reflux-management-system-is-it-a-permanent-solution-for-gerd
#14
Shirin Siddiqi, Saad Ullah, Najwa Pervin
No abstract text is available yet for this article.
April 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28351472/-the-missing-linx-for-gastroesophageal-reflux-disease-operative-techniques-video-for-the-linx-magnetic-sphincter-augmentation-procedure
#15
John P Kuckelman, Morgan R Barron, Matthew J Martin
In 2012 the FDA approved a magnetic sphincter augmentation (MSA) device (LINX, Torax Medical, Inc) for placement around the lower esophageal sphincter as an alternative approach to fundoplication for gastroesophageal reflux disease (GERD). This is a relatively new procedure and there is not widespread familiarization with the standard indications and techniques of device placement. We present two operative videos to highlight the standard surgical technique and technical points needed for successful LINX placement...
May 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28237427/three-dimensional-eye-shape-myopic-maculopathy-and-visual-acuity-the-zhongshan-ophthalmic-center-brien-holden-vision-institute-high-myopia-cohort-study
#16
Xinxing Guo, Ou Xiao, Yanxian Chen, Huawang Wu, Linxing Chen, Ian G Morgan, Mingguang He
PURPOSE: To investigate the relationship among eye shape, myopic maculopathy, and visual acuity in highly myopic eyes using 3-dimensional (3D) magnetic resonance imaging (MRI). DESIGN: Observational case series. PARTICIPANTS: The study included 190 eyes of 95 participants with bilateral high myopia from the Zhongshan Ophthalmic Center-Brien Holden Vision Institute High Myopia Cohort Study, with spherical power ≤-6.00 diopters (D) in both eyes...
May 2017: Ophthalmology
https://www.readbyqxmd.com/read/28207241/zero-thermal-expansion-and-semiconducting-properties-in-pbtio-3-bi-co-ti-o-3-ferroelectric-solid-solutions
#17
Zhao Pan, Jun Chen, Xingxing Jiang, Zheshuai Lin, Linxing Zhang, Longlong Fan, Yangchun Rong, Lei Hu, Hui Liu, Yang Ren, Xiaojun Kuang, Xianran Xing
Zero thermal expansion (ZTE) behavior is rare but important for both fundamental studies and practical applications of functional materials. Until now, most available ZTE materials are either electrical insulating oxides or conductive metallic compounds. Very few ZTE materials exhibit the semiconductor feature. Here we report a ZTE in a semiconducting ferroelectric of 0.6PbTiO3 -0.4Bi(Co0.55 Ti0.45 )O3-δ . Its unit cell volume exhibits a negligible change over a broad temperature range from room temperature to 500 °C...
March 6, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28180974/-surgical-and-interventional-procedures-for-reflux-therapy-endoscopic-or-laparoscopic
#18
K U Asche, A Kaindlstorfer, R Pointner
An optimal functioning of the gastroesophageal antireflux barrier depends on an anatomical overlapping of the lower esophageal sphincter and the crural diaphragm. Restoration of this situation is currently only possible by antireflux interventions combined with hiatoplasty and necessitates a laparoscopic approach. Newer alternative techniques to the generally accepted fundoplication are laparoscopic implantation of the LINX® device or the EndoStim® system and various endoscopic antireflux procedures, such as radiofrequency energy treatment, plication and implantation techniques aimed at augmentation of the gastroesophageal valve...
March 2017: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/28149546/localization-of-in-stent-neoatherosclerosis-in-relation-to-curvatures-and-bifurcations-after-stenting
#19
Yongpeng Zou, Xingtao Huang, Linxing Feng, Jingbo Hou, Lei Xing, Bo Yu
BACKGROUND: In-stent neoatherosclerosis (ISNA) is a final common pathway of late-stent failure. However, distribution of ISNA has been little reported. This study was to evaluate the localization of ISNA in relation to curvatures and bifurcations after stent implantation using optical coherence tomography (OCT). METHODS: We retrospectively selected patients who underwent OCT examination ≥12 months after stent (sirolimus-eluting stents, SES) implantation. A stent curvature was defined if the angulation of the stent segment was >29°...
December 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28012332/laparoscopic-management-of-severe-reflux-after-sleeve-gastrectomy-using-the-linx-%C3%A2-system-technique-and-one-year-follow-up-case-report
#20
Abdelkader Hawasli, Mark Tarakji, Moayad Tarboush
INTRODUCTION: Management of severe reflux after sleeve gastrectomy (SG) usually requires converting to Roux-en-y gastric bypass (RYGB). We present a case of managing this problem using the LINX® system. PRESENTATION OF CASE: In February 2015, we performed a laparoscopic placement of LINX® system to treat severe reflux after sleeve gastrectomy on a 25-year-old female. The operative time was 47min. There were no intra or postoperative complications. The hospital stay was one day...
2017: International Journal of Surgery Case Reports
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