Naoual El Menyiy, Youssef Elouafy, Rania Moubachir, Rhizlan Abdnim, Taoufiq Benali, Douae Taha, Asaad Khalid, Ashraf N Abdalla, Siddiqa M A Hamza, Salma Elhadi Ibrahim, Mohamed El-Shazly, Gokhan Zengin, Abdelhakim Bouyahya
Gastrodin, a bioactive compound derived from the rhizome of the orchid Gastrodia elata, exhibits a diverse range of biological activities. With documented neuroprotective, anti-inflammatory, antioxidant, anti-apoptotic, and anti-tumor effects, gastrodin stands out as a multifaceted therapeutic agent. Notably, it has demonstrated efficacy in protecting against neuronal damage and enhancing cognitive function in animal models of Alzheimer's disease, Parkinson's disease, and cerebral ischemia. Additionally, gastrodin showcases immunomodulatory effects by mitigating inflammation and suppressing the expression of inflammatory cytokines...
April 4, 2024: Chemistry & Biodiversity