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https://www.readbyqxmd.com/read/29908519/dna-identification-of-human-remains-in-disaster-victim-identification-dvi-an-efficient-sampling-method-for-muscle-bone-bone-marrow-and-teeth
#1
Hans H de Boer, George J R Maat, D Aji Kadarmo, Putut T Widodo, Ate D Kloosterman, Arnoud J Kal
In disaster victim identification (DVI), DNA profiling is considered to be one of the most reliable and efficient means to identify bodies or separated body parts. This requires a post mortem DNA sample, and an ante mortem DNA sample of the presumed victim or their biological relative(s). Usually the collection of an adequate ante mortem sample is technically simple, but the acquisition of a good quality post mortem sample under unfavourable DVI circumstances is complicated due to the variable degree of preservation of the human remains and the high risk of DNA (cross) contamination...
June 4, 2018: Forensic Science International
https://www.readbyqxmd.com/read/29762919/incremental-value-of-transesophageal-echocardiography-integrated-with-transthoracic-echocardiography-in-the-assessment-of-aortic-stenosis-severity
#2
Shmuel Schwartzenberg, Mordehay Vaturi, Shirit Kazum, Daniel Monakier, Alexander Sagie, Ran Kornowski, Yaron Shapira
BACKGROUND: Transthoracic echocardiography (TTE) is the standard method for evaluating the severity of aortic stenosis (AS), while transesophageal echocardiography (TEE) is useful for morphologic characterization. The study aim was to assess the impact of complementary TEE to TTE in refining hemodynamic assessment of AS severity. METHODS: A retrospective analysis was conducted of sequential TTE and TEE studies performed in 100 patients with moderate or severe AS confirmed on prior TTE...
September 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29727214/hemodynamic-effects-of-incremental-lung-hyperinflation
#3
William Spencer Cheyne, Jinelle C M Gelinas, Neil Derek Eves
Dynamic hyperinflation (DH) is common in COPD and is associated with dyspnea and exercise intolerance. DH also has adverse cardiac effects, though the magnitude of DH and the mechanisms responsible for the hemodynamic impairment remain unclear. We hypothesized that incrementally increasing DH would systematically reduce left-ventricular (LV) end diastolic volume (LVEDV) and stroke volume (LVSV) due to direct ventricular interaction (DVI). Twenty-three healthy subjects (22{plus minus}2yrs) were exposed to varying degrees of expiratory loading to induce DH such that inspiratory capacity (IC) was decreased by 25, 50, 75 and 100%, (100% DH = IC of resting tidal volume plus inspiratory reserve volume ≈0...
May 4, 2018: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/29685300/validation-studies-in-forensic-odontology-part-1-accuracy-of-radiographic-matching
#4
Mark Page, Russell Lain, Richard Kemp, Jane Taylor
As part of a series of studies aimed at validating techniques in forensic odontology, this study aimed to validate the accuracy of ante-mortem (AM)/postmortem (PM) radiographic matching by dentists and forensic odontologists. This study used a web-based interface with 50 pairs of AM and PM radiographs from real casework, at varying degrees of difficulty. Participants were shown both radiographs as a pair and initially asked to decide if they represented the same individual using a yes/no binary choice forced-decision...
May 2018: Science & Justice: Journal of the Forensic Science Society
https://www.readbyqxmd.com/read/29666997/forensic-answers-to-the-14th-of-july-2016-terrorist-attack-in-nice
#5
Gérald Quatrehomme, Steve Toupenay, Tania Delabarde, Bernard Padovani, Véronique Alunni
The terrorist attack of July 14, 2016 in Nice (France) was a devastating event. A man voluntarily drove a truck into a crowd gathered for the fireworks display on the seaside "Promenade des Anglais," plowing pedestrians down over more than 2 km before being shot dead. At the time of this report, a total of 86 casualties and more than 1200 formal complaints for physical and psychological injuries have been recorded. The aim of this work is to describe the forensic management of this event and its immediate aftermath...
April 17, 2018: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/29501225/quantification-of-disturbed-coronary-flow-by-disturbed-vorticity-index-and-relation-with-fractional-flow-reserve
#6
Miao Chu, Clemens von Birgelen, Yingguang Li, Jelmer Westra, Junqing Yang, Niels R Holm, Johan H C Reiber, William Wijns, Shengxian Tu
BACKGROUND AND AIMS: The relation between FFR and local coronary flow patterns is incompletely understood. We aimed at developing a novel hemodynamic index to quantify disturbed coronary flow, and to investigate its relationship with lesion-associated pressure-drop, and fractional flow reserve (FFR). METHODS: Three-dimensional angiographic reconstruction and computational fluid dynamics were applied to simulate pulsatile coronary flow. Disturbed vorticity index (DVI) was derived to quantify the stenosis-induced flow disturbance...
June 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29494786/disaster-victim-identification-psychological-distress-and-posttraumatic-stress-in-dentists-after-the-2011-fukushima-disaster
#7
Jun Shigemura, Hidetoshi Someda, Shinichi Tokuno, Masanori Nagamine, Masaaki Tanichi, Yoshiyuki Araki, Shinji Nagakawa, Taku Saito, Gentaro Tsumatori, Jin Itabashi, Akihiro Kanno
OBJECTIVE: To evaluate the correlates of psychological responses in dentists who conducted disaster victim identification (DVI) in Fukushima following the 2011 earthquake/tsunami/nuclear disaster. METHOD: Self-report questionnaires were administered to 49 male dentists six to nine months after the disaster. Psychological distress and posttraumatic stress were measured using the General Health Questionnaire-30 (GHQ-30) and Impact of Event Scale-Revised (IES-R), respectively...
March 1, 2018: Psychiatry
https://www.readbyqxmd.com/read/29384746/day-to-day-issues-in-the-forensic-identification-practice-related-to-illegal-immigration-in-italy
#8
V Pinchi, M Focardi, F Pradella, R Grifoni, M Palandri, G A Norelli
The migratory flows to Europe from the African countries, Asia and Middle East, have hugely intensified in the recent years. In 2016, more than 98,000 out of a total of 260,000 migrants across the Mediterranean Sea arrived in Italy and in May 2017, the trend of arrivals is: Italy +576%; Greece -39% compared to previous years. Some migrants die before touching the sole of the European continent, during the crossing, often afforded with ships, made available by unscrupulous smugglers or criminal organizations, which are unsuitable for this type of transportation...
December 1, 2017: Journal of Forensic Odonto-stomatology
https://www.readbyqxmd.com/read/29384745/forensic-odontology-education-from-undergraduate-to-phd-a-brazilian-experience
#9
J G Dietrichkeit Pereira, T S Frontanilla Recalde, P Barreto Costa, V Jacometti, L Vigorito Magalhães, R H Alves Da Silva
BACKGROUND: Forensic Odontology is a topic present in the majority of Dental Schools in Brazil, and due to this reality, some universities develop activities related to undergraduate and graduate students, from the Dentistry course until the Ph.D. degree. AIM: To present the education experience related to Forensic Odontology at School of Dentistry of Ribeirão Preto (USP - University of São Paulo), showing the strategies and activities in the different degrees (Dental course, Forensic Odontology Specialization Program, Specific Professional Training, Master, and Ph...
December 1, 2017: Journal of Forensic Odonto-stomatology
https://www.readbyqxmd.com/read/29378163/microparticles-as-prognostic-biomarkers-in-dengue-virus-infection
#10
Rucha Patil, Smrati Bajpai, Kanjaksha Ghosh, Shrimati Shetty
Promising biomarkers which may help predict the risk of developing severe dengue virus infection (DVI) are lacking and will be helpful. Thus the main aim of this study was to analyze the role of cell-derived microparticles (MP) in DVI. Sixty patients with DVI i.e. 18: dengue with warning signs (DWS); 1: DSS and 41: dengue without warning signs (DWOS); along with 15 controls (other febrile illness) were included in the study. The following MPs were assessed: annexinV, platelet (CD41a), red blood cell (RBC) (CD235a) and activated endothelial (CD62e) MPs...
May 2018: Acta Tropica
https://www.readbyqxmd.com/read/29377377/the-haemodynamic-response-to-incremental-increases-in-negative-intrathoracic-pressure-in-healthy-humans
#11
William S Cheyne, Jinelle C Gelinas, Neil D Eves
NEW FINDINGS: What is the central question of this study? The haemodynamic response to incremental increases in negative intrathoracic pressure (nITP) during spontaneous breathing and the mechanisms of cardiac impairment at these levels of nITP remain unclear. What is the main finding and its importance? nITP of -20 cmH2 O or greater reduces stroke volume in healthy, spontaneously breathing supine humans due to direct ventricular interaction and increased left ventricular afterload. ABSTRACT: Negative intrathoracic pressure (nITP) generally augments venous return and left ventricular (LV) stroke volume (LVSV), though large increases in nITP, commonly seen in respiratory disease, attenuate LVSV...
April 1, 2018: Experimental Physiology
https://www.readbyqxmd.com/read/29291357/associations-of-hypertensive-disorders-of-pregnancy-and-outcomes-of-labor-induction-with-prostaglandin-vaginal-inserts
#12
Lili Sheibani, Kyle Raymond, Olof Rugarn, Deborah A Wing
OBJECTIVE: To evaluate the association between hypertensive (HTNsive) disorders of pregnancy and outcomes of labor induction, in two cohorts of women induced with either misoprostol vaginal insert (MVI) or dinoprostone vaginal insert (DVI). STUDY DESIGN: This investigation was a post-hoc analysis of data from three Phase II and III, multi-center, double blind, randomized controlled trials of women induced with identical efficacy endpoints. A competing risk framework investigated the association between HTNsive disorders of pregnancy and the time-to-event endpoints of onset of active labor and vaginal delivery...
February 2018: Hypertension in Pregnancy
https://www.readbyqxmd.com/read/29260650/impact-of-sickle-cell-trait-and-naturally-acquired-immunity-on-uncomplicated-malaria-after-controlled-human-malaria-infection-in-adults-in-gabon
#13
Bertrand Lell, Benjamin Mordmüller, Jean-Claude Dejon Agobe, Josiane Honkpehedji, Jeannot Zinsou, Juliana Boex Mengue, Marguerite Massinga Loembe, Ayola Akim Adegnika, Jana Held, Albert Lalremruata, The Trong Nguyen, Meral Esen, Natasha Kc, Adam J Ruben, Sumana Chakravarty, B Kim Lee Sim, Peter F Billingsley, Eric R James, Thomas L Richie, Stephen L Hoffman, Peter G Kremsner
Controlled human malaria infection (CHMI) by direct venous inoculation (DVI) with 3,200 cryopreserved Plasmodium falciparum sporozoites (PfSPZ) consistently leads to parasitemia and malaria symptoms in malaria-naive adults. We used CHMI by DVI to investigate infection rates, parasite kinetics, and malaria symptoms in lifelong malaria-exposed (semi-immune) Gabonese adults with and without sickle cell trait. Eleven semi-immune Gabonese with normal hemoglobin (IA), nine with sickle cell trait (IS), and five nonimmune European controls with normal hemoglobin (NI) received 3,200 PfSPZ by DVI and were followed 28 days for parasitemia by thick blood smear (TBS) and quantitative polymerase chain reaction (qPCR) and for malaria symptoms...
February 2018: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28894961/digital-soil-mapping-using-remote-sensing-indices-terrain-attributes-and-vegetation-features-in-the-rangelands-of-northeastern-iran
#14
Ebrahim Mahmoudabadi, Alireza Karimi, Gholam Hosain Haghnia, Adel Sepehr
Digital soil mapping has been introduced as a viable alternative to the traditional mapping methods due to being fast and cost-effective. The objective of the present study was to investigate the capability of the vegetation features and spectral indices as auxiliary variables in digital soil mapping models to predict soil properties. A region with an area of 1225 ha located in Bajgiran rangelands, Khorasan Razavi province, northeastern Iran, was chosen. A total of 137 sampling sites, each containing 3-5 plots with 10-m interval distance along a transect established based on randomized-systematic method, were investigated...
September 11, 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28892844/are-optical-indices-good-proxies-of-seasonal-changes-in-carbon-fluxes-and-stress-related-physiological-status-in-a-beech-forest
#15
E Nestola, A Scartazza, D Di Baccio, A Castagna, A Ranieri, M Cammarano, F Mazzenga, G Matteucci, C Calfapietra
This study investigates the functionality of a Mediterranean-mountain beech forest in Central Italy using simultaneous determinations of optical measurements, carbon (C) fluxes, leaf eco-physiological and biochemical traits during two growing seasons (2014-2015). Meteorological variables showed significant differences between the two growing seasons, highlighting a heat stress coupled with a reduced water availability in mid-summer 2015. As a result, a different C sink capacity of the forest was observed between the two years of study, due to the differences in stressful conditions and the related plant physiological status...
January 15, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/28858673/evaluating-the-statistical-power-of-dna-based-identification-exemplified-by-the-missing-grandchildren-of-argentina
#16
Daniel Kling, Thore Egeland, Mariana Herrera Piñero, Magnus Dehli Vigeland
Methods and implementations of DNA-based identification are well established in several forensic contexts. However, assessing the statistical power of these methods has been largely overlooked, except in the simplest cases. In this paper we outline general methods for such power evaluation, and apply them to a large set of family reunification cases, where the objective is to decide whether a person of interest (POI) is identical to the missing person (MP) in a family, based on the DNA profile of the POI and available family members...
November 2017: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/28846914/two-halves-make-a-whole-both-first-responders-and-experts-are-needed-for-the-management-and-identification-of-the-dead-in-large-disasters
#17
S Cordner, S T D Ellingham
Catastrophic natural disasters are a regular global issue claiming thousands of lives and having severe and long lasting consequences for communities. Along with the rescue and care of survivors and the provision of basic services, managing the dead in a proper and dignified manner is one of the three pillars of disaster response. Since the 2004 Indian Ocean Tsunami, progress to facilitate better coordination in the management of the dead has been made. Two guidelines contributing to this positive trend are the Interpol DVI Guide, and the "Management of the Dead after Disasters - A Field Manual for First Responders"...
October 2017: Forensic Science International
https://www.readbyqxmd.com/read/28833187/rhd-genotype-and-zygosity-analysis-in-the-chinese-southern-han-d-d-and-d-variant-donors-using-the-multiplex-ligation-dependent-probe-amplification-assay
#18
Y L Ji, H Luo, J Z Wen, L Haer-Wigman, B Veldhuisen, L Wei, Z Wang, P Ligthart, M Lodén-van Straaten, Y S Fu, C E van der Schoot, G P Luo
BACKGROUND AND OBJECTIVES: Several comprehensive genotyping platforms for determining red blood cell (RBC) antigens have been established and validated for use in the Caucasian and Black populations, but not for the Chinese. The multiplex ligation-dependent probe amplification (MLPA) assay was validated for RHD genotyping in the Chinese. MATERIALS AND METHODS: The blood samples of 200 D+, 200 D- and 62 D variant Chinese donors were collected. RhD antigen was routinely typed by serological method...
October 2017: Vox Sanguinis
https://www.readbyqxmd.com/read/28806635/oryong-501-sinking-incident-in-the-bering-sea-international-dvi-cooperation-in-the-asia-pacific
#19
Nak-Eun Chung, Anton Castilani, Wilfredo E Tierra, Philip Beh, Mohd Shah Mahmood
On December 1st, 2014, the sinking of Oryong 501 occurred in the Bering Sea off the east coast of Russia. A total of 60 crew members, including 35 Indonesians, 13 Filipinos, 11 South Koreans and 1 Russian inspector were on board out of which only seven survived. Through an international rescue operation, the dead bodies of 27 were found and the remaining 26 crew are still missing. After transferring the dead bodies to the Busan Harbor in South Korea, the operation to identify the deceased began involving DVI teams from three countries: Korea, Indonesia and the Philippines...
September 2017: Forensic Science International
https://www.readbyqxmd.com/read/28755626/the-use-of-forensic-dna-analysis-in-humanitarian-forensic-action-the-development-of-a-set-of-international-standards
#20
William H Goodwin
DNA analysis was first applied to the identification of victims of armed conflicts and other situations of violence (ACOSV) in the mid-1990s, starting in South America and the Balkans. Argentina was the first country to establish a genetic database specifically developed to identify disappeared children. Following on from these programs the early 2000s marked major programs, using a largely DNA-led approach, identifying missing persons in the Balkans and following the attack on the World Trade Center in New York...
September 2017: Forensic Science International
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