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https://www.readbyqxmd.com/read/28408806/patient-knowledge-and-pulmonary-medication-adherence-in-adult-patients-with-cystic-fibrosis
#1
Ann Hsu-An Lin, Jennifer G Kendrick, Pearce G Wilcox, Bradley S Quon
BACKGROUND AND OBJECTIVES: Patient knowledge of lung function (ie, forced expiratory volume in 1 s [FEV1]% predicted) and the intended benefits of their prescribed pulmonary medications might play an important role in medication adherence, but this relationship has not been examined previously in patients with cystic fibrosis (CF). METHODS: All patients diagnosed with CF and without prior lung transplantation were invited to complete knowledge and self-reported medication adherence questionnaires during routine outpatient visits to the Adult CF Clinic, St Paul's Hospital, Vancouver, Canada from June 2013 to August 2014...
2017: Patient Preference and Adherence
https://www.readbyqxmd.com/read/28392009/genitourinary-and-gastrointestinal-co-morbidities-in-children-the-role-of-neural-circuits-in-regulation-of-visceral-function
#2
REVIEW
A P Malykhina, K E Brodie, D T Wilcox
OBJECTIVE: Pediatric lower urinary tract dysfunction (LUTD) is a common problem in childhood. Lower urinary tract symptoms in children include overactive bladder, voiding postponement, stress incontinence, giggle incontinence, and dysfunctional voiding. Gastrointestinal co-morbidities, including constipation or fecal incontinence, are commonly associated with lower urinary tract (LUT) symptoms in children, often reaching 22-34%. This review summarized the potential mechanisms underlying functional lower urinary and gastrointestinal co-morbidities in children...
June 15, 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28373692/a-missense-mutation-in-katnal1-underlies-behavioural-neurological-and-ciliary-anomalies
#3
G Banks, G Lassi, A Hoerder-Suabedissen, F Tinarelli, M M Simon, A Wilcox, P Lau, T N Lawson, S Johnson, A Rutman, M Sweeting, J E Chesham, A R Barnard, N Horner, H Westerberg, L B Smith, Z Molnár, M H Hastings, R A Hirst, V Tucci, P M Nolan
Microtubule severing enzymes implement a diverse range of tissue-specific molecular functions throughout development and into adulthood. Although microtubule severing is fundamental to many dynamic neural processes, little is known regarding the role of the family member Katanin p60 subunit A-like 1, KATNAL1, in central nervous system (CNS) function. Recent studies reporting that microdeletions incorporating the KATNAL1 locus in humans result in intellectual disability and microcephaly suggest that KATNAL1 may play a prominent role in the CNS; however, such associations lack the functional data required to highlight potential mechanisms which link the gene to disease symptoms...
April 4, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28372560/fish-sharing-as-a-risk-factor-for-opisthorchis-viverrini-infection-evidence-from-two-villages-in-north-eastern-thailand
#4
Parichat Saenna, Cameron Hurst, Pierre Echaubard, Bruce A Wilcox, Banchob Sripa
BACKGROUND: Foodborne trematodiasis (FBT) is a significant global health problem, with the liver flukes Opisthorchis viverrini, O. felineus, and Clonorchis sinensis contributing to half of the global burden of FBT. North-eastern Thailand where O. viverrini is endemic and un-cooked fish dishes remain an integral part of the food culture has the highest reported incidence of opisthorchiasis, including associated cholangiocarcinoma. Both food sharing and eating practices are potentially important factors in FTB, suggesting an important role for the social ecology of disease transmission in these rural communities...
April 4, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28370946/asymmetric-responses-of-primary-productivity-to-precipitation-extremes-a-synthesis-of-grassland-precipitation-manipulation-experiments
#5
Kevin R Wilcox, Zheng Shi, Laureano A Gherardi, Nathan P Lemoine, Sally E Koerner, David L Hoover, Edward Bork, Kerry M Byrne, James Cahill, Scott L Collins, Sarah Evans, Anna Katarina Gilgen, Petr Holub, Lifen Jiang, Alan K Knapp, Daniel LeCain, Junyi Liang, Pablo Garcia-Palacios, Josep Peñuelas, William T Pockman, Melinda D Smith, Shanghua Sun, Shannon R White, Laura Yahdjian, Kai Zhu, Yiqi Luo
Climatic changes are altering Earth's hydrological cycle, resulting in altered precipitation amounts, increased inter-annual variability of precipitation, and more frequent extreme precipitation events. These trends will likely continue into the future, having substantial impacts on net primary productivity (NPP) and associated ecosystem services such as food production and carbon sequestration. Frequently, experimental manipulations of precipitation have linked altered precipitation regimes to changes in NPP...
April 2, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28367786/is-agree-ii-a-counsel-of-perfection-a-letter-commenting-on-lytvyn-et-al
#6
Sheldon P Stone, Mark Wilcox, Peter Hawkey
No abstract text is available yet for this article.
April 3, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/28366811/the-association-between-food-security-and-store-specific-and-overall-food-shopping-behaviors
#7
Xiaonan Ma, Angela D Liese, James Hibbert, Bethany A Bell, Sara Wilcox, Patricia A Sharpe
BACKGROUND: Food security is a severe problem in the United States. Few studies have examined its relationship with food shopping behaviors. OBJECTIVE: This study aimed to examine the association between food security and store-specific and overall food shopping among residents of low-income neighborhoods. DESIGN: We conducted a cross-sectional study. PARTICIPANTS/SETTING: Five hundred twenty-seven households were recruited from two counties in South Carolina from November 2013 to May 2014, and 474 households were included in the final analysis...
March 30, 2017: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/28351774/rifm-fragrance-ingredient-safety-assessment-methyl-jasmonate-cas-registry-number-1211-29-6
#8
A M Api, D Belsito, S Bhatia, D Botelho, D Browne, M Bruze, G A Burton, J Buschmann, P Calow, M L Dagli, M Date, W Dekant, C Deodhar, A D Fryer, K Joshi, L Kromidas, S La Cava, J F Lalko, A Lapczynski, D C Liebler, D O'Brien, R Parakhia, A Patel, T M Penning, V T Politano, G Ritacco, J Romine, D Salvito, T W Schultz, J Shen, I G Sipes, Y Thakkar, S Tsang, J Wahler, B Wall, D K Wilcox
No abstract text is available yet for this article.
March 25, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28344829/systemic-angiopoietin-1-2-dysregulation-following-cardiopulmonary-bypass-in-adults
#9
Emmanuel Charbonney, Elizabeth Wilcox, Yuexin Shan, Pablo Perez d'Empaire, Abhijit Duggal, Gordon D Rubenfeld, Conrad Liles, Claudia Dos Santos
AIM: Vascular leakage following cardiopulmonary bypass contributes to morbidity. Angiopoietin-1 and -2 are biomarkers of endothelial dysfunction. Our aim was to characterize Ang-1 and -2 association with clinical characteristics and outcomes. METHODS: Observational cohort study measuring Ang-1/-2 with a panel of cytokines in adults undergoing cardiopulmonary bypass. RESULTS: Ang-2 levels increased immediately postop whereas Ang-1 levels decreased over time...
March 2017: Future Science OA
https://www.readbyqxmd.com/read/28323905/elevated-plasma-levels-of-cardiac-troponin-i-predict-left-ventricular-systolic-dysfunction-in-patients-with-myotonic-dystrophy-type-1-a-multicentre-cohort-follow-up-study
#10
Mark J Hamilton, Yvonne Robb, Sarah Cumming, Helen Gregory, Alexis Duncan, Monika Rahman, Anne McKeown, Catherine McWilliam, John Dean, Alison Wilcox, Maria E Farrugia, Anneli Cooper, Josephine McGhie, Berit Adam, Richard Petty, Cheryl Longman, Iain Findlay, Alan Japp, Darren G Monckton, Martin A Denvir
OBJECTIVE: High sensitivity plasma cardiac troponin-I (cTnI) is emerging as a strong predictor of cardiac events in a variety of settings. We have explored its utility in patients with myotonic dystrophy type 1 (DM1). METHODS: 117 patients with DM1 were recruited from routine outpatient clinics across three health boards. A single measurement of cTnI was made using the ARCHITECT STAT Troponin I assay. Demographic, ECG, echocardiographic and other clinical data were obtained from electronic medical records...
2017: PloS One
https://www.readbyqxmd.com/read/28287095/aboriginal-australian-mitochondrial-genome-variation-an-increased-understanding-of-population-antiquity-and-diversity
#11
Nano Nagle, Mannis van Oven, Stephen Wilcox, Sheila van Holst Pellekaan, Chris Tyler-Smith, Yali Xue, Kaye N Ballantyne, Leah Wilcox, Luka Papac, Karen Cooke, Roland A H van Oorschot, Peter McAllister, Lesley Williams, Manfred Kayser, R John Mitchell
Aboriginal Australians represent one of the oldest continuous cultures outside Africa, with evidence indicating that their ancestors arrived in the ancient landmass of Sahul (present-day New Guinea and Australia) ~55 thousand years ago. Genetic studies, though limited, have demonstrated both the uniqueness and antiquity of Aboriginal Australian genomes. We have further resolved known Aboriginal Australian mitochondrial haplogroups and discovered novel indigenous lineages by sequencing the mitogenomes of 127 contemporary Aboriginal Australians...
March 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28279898/concern-about-developing-alzheimer-s-disease-or-dementia-and-intention-to-be-screened-an-analysis-of-national-survey-data
#12
Weizhou Tang, Kristie Kannaley, Daniela B Friedman, Valerie J Edwards, Sara Wilcox, Sue E Levkoff, Rebecca H Hunter, Cheryl Irmiter, Basia Belza
OBJECTIVE: Early diagnosis of Alzheimer's disease (AD) or dementia is important so that patients can express treatment preferences, subsequently allowing caregivers to make decisions consistent with their wishes. This study explored the relationship between people's concern about developing AD/dementia, likelihood to be screened/tested, if experiencing changes in cognitive status or functioning, and concerns about sharing the diagnostic information with others. METHOD: A descriptive study was conducted using Porter Novelli's SummerStyles 2013 online survey data...
March 1, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28269681/a-three-element-1h-31p-dual-tuned-array-for-magnetic-resonance-spectroscopy-at-4-7-t
#13
Matthew D Wilcox, Romina Del Bosque, Kurt Parizek, Jeremy Sia, Edwin D Eigenbrodt, Mary P McDougall
This work describes the construction and testing of a three-element, double-tuned receive array and transmit coils for 31P-1H spectroscopy and imaging. The receive coils were geometrically-decoupled, single-loop surface coils and the transmit coils were concentric saddle coils. The coils were used to examine a physiologically-modeled CNC-milled phantom. The receive coil array was able to improve SNR while also providing gross localization of the 1H and 31P signals.
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28269680/effects-of-coplanar-shielding-for-high-field-mri
#14
Joseph V Rispoli, Matthew D Wilcox, Samantha By, Steven M Wright, Mary P McDougall
This work investigates the efficacy of "coplanar shielding," in which copper shields are oriented concentric and coplanar to the RF coils rather than implemented as a full ground plane behind them. Following FDTD simulations to determine optimal shielding parameters, two coil geometries were constructed: a circular loop surface coil and a half-volume five-element receive array. Each was evaluated using bench measurements with and without coplanar shielding. Imaging, including accelerated SENSE imaging, was performed with the shielded and unshielded receive arrays on a whole-body 7T scanner...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28263866/rifm-fragrance-ingredient-safety-assessment-d-cyclocitronellene-acetate-cas-registry-number-25225-10-9
#15
A M Api, D Belsito, S Bhatia, D Botelho, D Browne, M Bruze, G A Burton, J Buschmann, P Calow, M L Dagli, M Date, W Dekant, C Deodhar, A D Fryer, L Kromidas, S La Cava, J Lalko, A Lapczynski, D C Liebler, Y Miyachi, D O'brien, R Parakhia, A Patel, T M Penning, V T Politano, G Ritacco, J Romine, D Salvito, T W Schultz, J Shen, I G Sipes, Y Thakkar, S Tsang, J Wahler, B Wall, D K Wilcox
No abstract text is available yet for this article.
March 2, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28245999/rifm-fragrance-ingredient-safety-assessment-isolongifolene-ketone-cas-registry-number-23787-90-8
#16
A M Api, D Belsito, S Bhatia, D Botelho, D Brown, M Bruze, G A Burton, J Buschmann, P Calow, M L Dagli, M Date, W Dekant, A D Fryer, L Kromidas, J Lalko, S La Cava, A Lapczynski, D C Liebler, D O'brien, R Parakhia, A Patel, T M Penning, V T Politano, G Ritacco, J Romine, D Salvito, T W Schultz, J Shen, I G Sipes, Y Thakkar, J Wahler, B Wall, D K Wilcox
No abstract text is available yet for this article.
February 25, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28244497/quality-of-life-in-chronic-pancreatitis-is-determined-by-constant-pain-disability-unemployment-current-smoking-and-associated-co-morbidities
#17
Jorge D Machicado, Stephen T Amann, Michelle A Anderson, Judah Abberbock, Stuart Sherman, Darwin L Conwell, Gregory A Cote, Vikesh K Singh, Michele D Lewis, Samer Alkaade, Bimaljit S Sandhu, Nalini M Guda, Thiruvengadam Muniraj, Gong Tang, John Baillie, Randall E Brand, Timothy B Gardner, Andres Gelrud, Christopher E Forsmark, Peter A Banks, Adam Slivka, C Mel Wilcox, David C Whitcomb, Dhiraj Yadav
OBJECTIVES: Chronic pancreatitis (CP) has a profound independent effect on quality of life (QOL). Our aim was to identify factors that impact the QOL in CP patients. METHODS: We used data on 1,024 CP patients enrolled in the three NAPS2 studies. Information on demographics, risk factors, co-morbidities, disease phenotype, and treatments was obtained from responses to structured questionnaires. Physical and mental component summary (PCS and MCS, respectively) scores generated using responses to the Short Form-12 (SF-12) survey were used to assess QOL at enrollment...
April 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28242154/systematic-review-and-meta-analysis-of-the-effect-of-internal-iliac-artery-exclusion-for-patients-undergoing-evar
#18
REVIEW
D C Bosanquet, C Wilcox, L Whitehurst, A Cox, I M Williams, C P Twine
OBJECTIVE: Endovascular abdominal aortic aneurysm repair (EVAR) sometimes requires internal iliac artery (IIA) coverage to achieve a landing zone in the external iliac artery. The aim of this study was to determine complication rates following IIA exclusion. MATERIALS AND METHODS: A systematic review of key journals was undertaken from January 1980 to April 2016. Studies detailing occlusion (using coils or plugs) or coverage of the IIA with outcome data were included...
February 24, 2017: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/28231626/default-mode-network-deactivation-to-smoking-cue-relative-to-food-cue-predicts-treatment-outcome-in-nicotine-use-disorder
#19
Claire E Wilcox, Eric D Claus, Vince D Calhoun, Srinivas Rachakonda, Rae A Littlewood, Jessica Mickey, Pamela B Arenella, Natalie Goodreau, Kent E Hutchison
Identifying predictors of treatment outcome for nicotine use disorders (NUDs) may help improve efficacy of established treatments, like varenicline. Brain reactivity to drug stimuli predicts relapse risk in nicotine and other substance use disorders in some studies. Activity in the default mode network (DMN) is affected by drug cues and other palatable cues, but its clinical significance is unclear. In this study, 143 individuals with NUD (male n = 91, ages 18-55 years) received a functional magnetic resonance imaging scan during a visual cue task during which they were presented with a series of smoking-related or food-related video clips prior to randomization to treatment with varenicline (n = 80) or placebo...
February 23, 2017: Addiction Biology
https://www.readbyqxmd.com/read/28230419/the-association-between-physical-performance-and-executive-function-in-a-sample-of-rural-older-adults-from-south-carolina-usa
#20
Ryan S Falck, Sara Wilcox, John R Best, Jessica L Chandler, Teresa Liu-Ambrose
BACKGROUND: Mobility and executive functions (EFs) decline with age, although associations between mobility and EFs are less clear. This study examined relationships between different mobility measures and EFs among rural older adults. METHODS: This cross-sectional study recruited 56 older adults (60+ years) in rural South Carolina. Mobility was assessed via gait speed, timed up-and-go, chair stand, and as a composite physical performance score (PPS). EFs was assessed via Trail Making Test, semantic fluency, and phonemic fluency...
March 2017: Experimental Aging Research
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