keyword
MENU ▼
Read by QxMD icon Read
search

Einspieler

keyword
https://www.readbyqxmd.com/read/29774230/early-vocal-development-in-autism-spectrum-disorder-rett-syndrome-and-fragile-x-syndrome-insights-from-studies-using-retrospective-video-analysis
#1
Laura Roche, Dajie Zhang, Katrin D Bartl-Pokorny, Florian B Pokorny, Björn W Schuller, Gianluca Esposito, Sven Bölte, Herbert Roeyers, Luise Poustka, Markus Gugatschka, Hannah Waddington, Ralf Vollmann, Christa Einspieler, Peter B Marschik
This article provides an overview of studies assessing the early vocalisations of children with autism spectrum disorder (ASD), Rett syndrome (RTT), and fragile X syndrome (FXS) using retrospective video analysis (RVA) during the first two years of life. Electronic databases were systematically searched and a total of 23 studies were selected. These studies were then categorised according to whether children were later diagnosed with ASD (13 studies), RTT (8 studies), or FXS (2 studies), and then described in terms of (a) participant characteristics, (b) control group characteristics, (c) video footage, (d) behaviours analysed, and (e) main findings...
March 2018: Advances in Neurodevelopmental Disorders
https://www.readbyqxmd.com/read/29668025/general-movements-a-behavioral-biomarker-of-later-motor-and-cognitive-dysfunction-in-nicu-graduates
#2
Colleen Peyton, Christa Einspieler
Infants who have graduated from a neonatal intensive care unit require close follow-up because they have a greater chance of experiencing later motor and cognitive difficulties; however, these difficulties are often challenging to identify at an early age. The General Movement Assessment is a low-cost and highly reliable tool that can indicate abnormal neurological development in young high-risk infants, but it has not yet been widely implemented in the United States. In this review, we discuss the literature about the use of the General Movement Assessment in high-risk infants and how to implement the tool in a clinical setting...
April 1, 2018: Pediatric Annals
https://www.readbyqxmd.com/read/29655507/response-to-name-and-its-value-for-the-early-detection-of-developmental-disorders-insights-from-autism-spectrum-disorder-rett-syndrome-and-fragile-x-syndrome-a-perspectives-paper
#3
Dajie Zhang, Laura Roche, Katrin D Bartl-Pokorny, Magdalena Krieber, Laurie McLay, Sven Bölte, Luise Poustka, Jeff Sigafoos, Markus Gugatschka, Christa Einspieler, Peter B Marschik
BACKGROUND: Responding to one's own name (RtN) has been reported as atypical in children with developmental disorders, yet comparative studies on RtN across syndromes are rare. AIMS: We aim to (a) overview the literature on RtN in different developmental disorders during the first 24 months of life, and (b) report comparative data on RtN across syndromes. METHODS AND PROCEDURES: In Part 1, a literature search, focusing on RtN in children during the first 24 months of life with developmental disorders, identified 23 relevant studies...
April 11, 2018: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29551600/typical-vs-atypical-combining-auditory-gestalt-perception-and-acoustic-analysis-of-early-vocalisations-in-rett-syndrome
#4
Florian B Pokorny, Katrin D Bartl-Pokorny, Christa Einspieler, Dajie Zhang, Ralf Vollmann, Sven Bölte, Markus Gugatschka, Björn W Schuller, Peter B Marschik
BACKGROUND: Early speech-language development of individuals with Rett syndrome (RTT) has been repeatedly characterised by a co-occurrence of apparently typical and atypical vocalisations. AIMS: To describe specific features of this intermittent character of typical versus atypical early RTT-associated vocalisations by combining auditory Gestalt perception and acoustic vocalisation analysis. METHODS AND PROCEDURES: We extracted N = 363 (pre-)linguistic vocalisations from home video recordings of an infant later diagnosed with RTT...
March 15, 2018: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29412374/the-general-movement-assessment-in-non-european-low-and-middle-income-countries
#5
REVIEW
Iris Tomantschger, Dafne Herrero, Christa Einspieler, Cristina Hamamura, Mariana Calil Voos, Peter B Marschik
Abnormal general movements are among the most reliable markers for cerebral palsy. General movements are part of the spontaneous motor repertoire and are present from early fetal life until the end of the first half year after term. In addition to its high sensitivity (98%) and specificity (91%), the assessment of general movements is non-invasive and time- and cost-efficient. It is therefore ideal for assessing the integrity of the young nervous system, most notably in lowresource settings. Studies on the general movements assessment in low- and middle-income countries such as China, India, Iran, or South Africa are still rare but increasing...
February 5, 2018: Revista de Saúde Pública
https://www.readbyqxmd.com/read/29144840/feasibility-of-using-the-general-movements-assessment-of-infants-in-the-united-states
#6
Eileen Ricci, Christa Einspieler, Alexa K Craig
AIMS: To pilot the practicality of administering the Prechtl General Movements Assessment of infants (GMA) in the Neonatal Intensive Care Unit (NICU) setting and at home to infants at risk for developing cerebral palsy (CP). Additional aims included assessing inter-rater reliability and comparing GMA predictions to AIMS motor assessment at 12 months. METHODS: 12 "at risk" infants were recruited by convenience sample. Video recordings were obtained in the NICU and provided by parents after discharge...
August 2018: Physical & Occupational Therapy in Pediatrics
https://www.readbyqxmd.com/read/28715518/early-accurate-diagnosis-and-early-intervention-in-cerebral-palsy-advances-in-diagnosis-and-treatment
#7
REVIEW
Iona Novak, Cathy Morgan, Lars Adde, James Blackman, Roslyn N Boyd, Janice Brunstrom-Hernandez, Giovanni Cioni, Diane Damiano, Johanna Darrah, Ann-Christin Eliasson, Linda S de Vries, Christa Einspieler, Michael Fahey, Darcy Fehlings, Donna M Ferriero, Linda Fetters, Simona Fiori, Hans Forssberg, Andrew M Gordon, Susan Greaves, Andrea Guzzetta, Mijna Hadders-Algra, Regina Harbourne, Angelina Kakooza-Mwesige, Petra Karlsson, Lena Krumlinde-Sundholm, Beatrice Latal, Alison Loughran-Fowlds, Nathalie Maitre, Sarah McIntyre, Garey Noritz, Lindsay Pennington, Domenico M Romeo, Roberta Shepherd, Alicia J Spittle, Marelle Thornton, Jane Valentine, Karen Walker, Robert White, Nadia Badawi
Importance: Cerebral palsy describes the most common physical disability in childhood and occurs in 1 in 500 live births. Historically, the diagnosis has been made between age 12 and 24 months but now can be made before 6 months' corrected age. Objectives: To systematically review best available evidence for early, accurate diagnosis of cerebral palsy and to summarize best available evidence about cerebral palsy-specific early intervention that should follow early diagnosis to optimize neuroplasticity and function...
September 1, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28638739/ewing-sarcoma-partial-regression-without-gvhd-by-chondromodulin-i-hla-a-02-01-specific-allorestricted-t-cell-receptor-transgenic-t-cells
#8
Uwe Thiel, Sebastian J Schober, Ingo Einspieler, Andreas Kirschner, Melanie Thiede, David Schirmer, Katja Gall, Franziska Blaeschke, Oxana Schmidt, Susanne Jabar, Andreas Ranft, Rebeca Alba Rubío, Uta Dirksen, Thomas G P Grunewald, Poul H Sorensen, Günther H S Richter, Irene Teichert von Lüttichau, Dirk H Busch, Stefan E G Burdach
Background: Chondromodulin-I (CHM1) sustains malignancy in Ewing sarcoma (ES). Refractory ES carries a dismal prognosis and patients with bone marrow (BM) metastases do not survive irrespective of therapy. We assessed HLA-A*02:01/CHM1-specific allorestricted T cell receptor (TCR) wild-type and transgenic cytotoxic (CD8(+)) T cells against ES. Patients and Methods: Three refractory HLA-A2(+) ES patients were treated with HLA-A*02:01/peptide-specific allorepertoire-derived (i.e., allorestricted) CD8(+) T cells...
2017: Oncoimmunology
https://www.readbyqxmd.com/read/28586709/the-motor-repertoire-in-3-to-5-month-old-infants-with-down-syndrome
#9
Dafne Herrero, Christa Einspieler, Carolina Y Panvequio Aizawa, Akmer Mutlu, Hong Yang, Alice Nogolová, Jasmin Pansy, Karin Nielsen-Saines, Peter B Marschik
BACKGROUND: Even though Down syndrome is the most common chromosomal cause of intellectual disability, studies on early development are scarce. AIM: To describe movements and postures in 3- to 5-month-old infants with Down syndrome and assess the relation between pre- and perinatal risk factors and the eventual motor performance. METHODS AND PROCEDURES: Exploratory study; 47 infants with Down syndrome (26 males, 27 infants born preterm, 22 infants with congenital heart disease) were videoed at 10-19 weeks post-term (median=14 weeks)...
August 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/28549271/the-association-between-the-early-motor-repertoire-and-language-development-in-term-children-born-after-normal-pregnancy
#10
Sahar Salavati, Christa Einspieler, Giulia Vagelli, Dajie Zhang, Jasmin Pansy, Johannes G M Burgerhof, Peter B Marschik, Arend F Bos
BACKGROUND: The assessment of the early motor repertoire is a widely used method for assessing the infant's neurological status. AIM: To determine the association between the early motor repertoire and language development. STUDY DESIGN: Prospective cohort study. SUBJECTS: 22 term children born after normal pregnancy; video recorded for the assessment of the early motor repertoire including their motor optimality score (MOS), according to Prechtl, at 3 and 5months post term...
August 2017: Early Human Development
https://www.readbyqxmd.com/read/28534656/early-development-in-rett-syndrome-the-benefits-and-difficulties-of-a-birth-cohort-approach
#11
Peter B Marschik, Sanne Lemcke, Christa Einspieler, Dajie Zhang, Sven Bölte, Gillian S Townend, Marlene B Lauritsen
PURPOSES: Typically, early (pre-diagnostic) development in individuals later diagnosed with Rett syndrome (RTT) has been investigated retrospectively using parent reports, medical records and analysis of home videos. In recent years, prospective research designs have been increasingly applied to the investigation of early development in individuals with late phenotypical onset disorders, for example, autism spectrum disorder. METHODS: In this study, data collected by the Danish National Birth Cohort lent itself to prospective exploration of the early development of RTT, in particular early motor-, speech-language, and socio-communicative behaviors, mood, and sleep...
January 2018: Developmental Neurorehabilitation
https://www.readbyqxmd.com/read/28390033/a-novel-way-to-measure-and-predict-development-a-heuristic-approach-to-facilitate-the-early-detection-of-neurodevelopmental-disorders
#12
REVIEW
Peter B Marschik, Florian B Pokorny, Robert Peharz, Dajie Zhang, Jonathan O'Muircheartaigh, Herbert Roeyers, Sven Bölte, Alicia J Spittle, Berndt Urlesberger, Björn Schuller, Luise Poustka, Sally Ozonoff, Franz Pernkopf, Thomas Pock, Kristiina Tammimies, Christian Enzinger, Magdalena Krieber, Iris Tomantschger, Katrin D Bartl-Pokorny, Jeff Sigafoos, Laura Roche, Gianluca Esposito, Markus Gugatschka, Karin Nielsen-Saines, Christa Einspieler, Walter E Kaufmann
PURPOSE OF REVIEW: Substantial research exists focusing on the various aspects and domains of early human development. However, there is a clear blind spot in early postnatal development when dealing with neurodevelopmental disorders, especially those that manifest themselves clinically only in late infancy or even in childhood. RECENT FINDINGS: This early developmental period may represent an important timeframe to study these disorders but has historically received far less research attention...
May 2017: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/28209912/detection-efficacy-of-hybrid-68-ga-psma-ligand-pet-ct-in-prostate-cancer-patients-with-biochemical-recurrence-after-primary-radiation-therapy-defined-by-phoenix-criteria
#13
Ingo Einspieler, Isabel Rauscher, Charlotte Düwel, Markus Krönke, Christoph Rischpler, Gregor Habl, Sabrina Dewes, Armin Ott, Hans-Jürgen Wester, Markus Schwaiger, Tobias Maurer, Matthias Eiber
The aim of this retrospective study was to evaluate the detection rate of Glu-NH-CO-NH-Lys-(Ahx)-[68 Ga(HBED-CC)] (68 Ga-PSMA ligand; PSMA is prostate-specific membrane antigen) PET/CT in patients with biochemical recurrent prostate cancer defined by Phoenix criteria after external-beam radiotherapy or brachytherapy as primary treatment. Methods: One hundred eighteen patients with a median prostate-specific antigen (PSA) of 6.4 ng/mL (range, 2.2-158.4 ng/mL; interquartile range, 4.2-10.2 ng/mL) were finally eligible for this retrospective analysis...
July 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28151950/eye-movements-during-silent-and-oral-reading-in-a-regular-orthography-basic-characteristics-and-correlations-with-childhood-cognitive-abilities-and-adolescent-reading-skills
#14
Magdalena Krieber, Katrin D Bartl-Pokorny, Florian B Pokorny, Dajie Zhang, Karin Landerl, Christof Körner, Franz Pernkopf, Thomas Pock, Christa Einspieler, Peter B Marschik
The present study aimed to define differences between silent and oral reading with respect to spatial and temporal eye movement parameters. Eye movements of 22 German-speaking adolescents (14 females; mean age = 13;6 years;months) were recorded while reading an age-appropriate text silently and orally. Preschool cognitive abilities were assessed at the participants' age of 5;7 (years;months) using the Kaufman Assessment Battery for Children. The participants' reading speed and reading comprehension at the age of 13;6 (years;months) were determined using a standardized inventory to evaluate silent reading skills in German readers (Lesegeschwindigkeits- und -verständnistest für Klassen 6-12)...
2017: PloS One
https://www.readbyqxmd.com/read/27974103/disease-activity-and-vascular-involvement-in-retroperitoneal-fibrosis-first-experience-with-fully-integrated-18f-fluorodeoxyglucose-positron-emission-tomography-magnetic-resonance-imaging-compared-to-clinical-and-laboratory-parameters
#15
COMPARATIVE STUDY
Klaus Thuermel, Ingo Einspieler, Sabine Wolfram, Philipp Moog, Reinhard Meier, Markus Schwaiger, Uwe Heemann
OBJECTIVES: The aim of this study was to evaluate the value of fully integrated [18F]-FDG PET/MRI in the assessment of retroperitoneal fibrosis with regard to disease activity, extent and vascular involvement compared to clinical and laboratory parameters. METHODS: Seventeen [18F]-FDG PET/MRI examinations were performed in fourteen patients. Qualitative (visual 4-point scale) and quantitative PET parameters (maximum standardised uptake value, SUVmax; target-background ratio, TBR) as well as RF thickness and volume were correlated to clinical and inflammatory parameters and compared between therapy-naïve patients and patients under immunosuppression...
March 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/27863327/autism-spectrum-disorder-and-early-motor-abnormalities-connected-or-coincidental-companions
#16
REVIEW
Peipei Setoh, Peter B Marschik, Christa Einspieler, Gianluca Esposito
Research in the past decade has produced a growing body of evidence showing that motor abnormalities in individuals with autism spectrum disorder (ASD) are the rule rather than the exception. The paper by Chinello and colleagues furthers our understanding of the importance of studying motor functions in ASD by testing a non-clinical population of parents-infant triads. Chinello and colleagues' findings seem to suggest that subclinical motor impairments may exist in the typical population with inherited non-clinical ASD traits...
January 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/27825041/the-ontogeny-of-fidgety-movements-from-4-to-20weeks-post-term-age-in-healthy-full-term-infants
#17
Fabrizio Ferrari, Rossella Frassoldati, Alberto Berardi, Francesca Di Palma, Luca Ori, Laura Lucaccioni, Natascia Bertoncelli, Christa Einspieler
BACKGROUND: Fidgety movements (FMs) are an early accurate marker for normal development. AIM: The study assessed the ontogeny of normal FMs from 4 to 20weeks post-term age (PTA). STUDY DESIGN: Longitudinal prospective study of healthy full-term infants video recorded every second week from birth to 20weeks PTA. SUBJECTS: 21 full-term newborns were enrolled. OUTCOME MEASURES: Temporal organization, amplitude, character, predominance in proximal and/or distal parts of the body and the presence of FMs in fingers and wrists were independently scored by three observers...
December 2016: Early Human Development
https://www.readbyqxmd.com/read/27789448/white-matter-injury-and-general-movements-in-high-risk-preterm-infants
#18
C Peyton, E Yang, M E Msall, L Adde, R Støen, T Fjørtoft, A F Bos, C Einspieler, Y Zhou, M D Schreiber, J D Marks, A Drobyshevsky
BACKGROUND AND PURPOSE: Very preterm infants (birth weight, <1500 g) are at increased risk of cognitive and motor impairment, including cerebral palsy. These adverse neurodevelopmental outcomes are associated with white matter abnormalities on MR imaging at term-equivalent age. Cerebral palsy has been predicted by analysis of spontaneous movements in the infant termed "General Movement Assessment." The goal of this study was to determine the utility of General Movement Assessment in predicting adverse cognitive, language, and motor outcomes in very preterm infants and to identify brain imaging markers associated with both adverse outcomes and aberrant general movements...
January 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/27697883/the-baby-moves-prospective-cohort-study-protocol-using-a-smartphone-application-with-the-general-movements-assessment-to-predict-neurodevelopmental-outcomes-at-age-2-years-for-extremely-preterm-or-extremely-low-birthweight-infants
#19
A J Spittle, J Olsen, A Kwong, L W Doyle, P B Marschik, C Einspieler, Jly Cheong
INTRODUCTION: Infants born extremely preterm (EP; <28 weeks' gestation) and/or with extremely low birth weight (ELBW; <1000 g birth weight) are at increased risk for adverse neurodevelopmental outcomes. However, it is challenging to predict those EP/ELBW infants destined to have long-term neurodevelopmental impairments in order to target early intervention to those in most need. The General Movements Assessment (GMA) in early infancy has high predictive validity for neurodevelopmental outcomes in preterm infants...
October 3, 2016: BMJ Open
https://www.readbyqxmd.com/read/27514944/behavioural-biomarkers-of-typical-rett-syndrome-moving-towards-early-identification
#20
Christa Einspieler, Michael Freilinger, Peter B Marschik
The dynamic course of Rett syndrome (RTT) is still said to begin with a period of apparently normal development although there is mounting evidence that individuals with RTT show behavioural peculiarities and abnormalities during their infancy. Their spontaneous general movements are abnormal from birth onwards. Normal cooing vocalisation and canonical babbling (if at all required) are interspersed with abnormalities such as proto-vowel and proto-consonant alternations produced on ingressive airstream, breathy voice characteristics, and pressed or high-pitched vocalisations...
September 2016: Wiener Medizinische Wochenschrift
keyword
keyword
58418
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"