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https://www.readbyqxmd.com/read/29042827/use-of-a-problem-based-learning-teaching-model-for-undergraduate-medical-and-nursing-education-a-systematic-review-and-meta-analysis
#1
REVIEW
Mehdi Sayyah, Kiarash Shirbandi, Amal Saki-Malehi, Fakher Rahim
OBJECTIVES: The aim of this systematic review and meta-analysis was to evaluate the problem-based learning (PBL) method as an alternative to conventional educational methods in Iranian undergraduate medical courses. MATERIALS AND METHODS: We systematically searched international datasets banks, including PubMed, Scopus, and Embase, and internal resources of banks, including MagirIran, IranMedex, IranDoc, and Scientific Information Database (SID), using appropriate search terms, such as "PBL", "problem-based learning", "based on problems", "active learning", and" learner centered", to identify PBL studies, and these were combined with other key terms such as "medical", "undergraduate", "Iranian", "Islamic Republic of Iran", "I...
2017: Advances in Medical Education and Practice
https://www.readbyqxmd.com/read/29032293/facilitating-problem-based-learning-among-undergraduate-nursing-students-a-qualitative-systematic-review
#2
REVIEW
Jacqueline Wosinski, Anne E Belcher, Yvan Dürrenberger, Anne-Claude Allin, Coraline Stormacq, Linda Gerson
OBJECTIVES: The purpose of this study was to identify and synthesize the best available evidence on the perspective of undergraduate nursing students on facilitating elements that contribute to their success with PBL. DESIGN: a qualitative systematic review of the literature according to meta-aggregative methodology using the JBI SUMARI system was conducted. DATA SOURCES: Data was collected across CINAHL, Medline, Embase, Eric, Teacher Reference Center and reference lists...
September 8, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/29029989/the-effect-of-demographic-and-disease-variables-on-schneiderian-membrane-thickness-and-appearance
#3
Tuba Talo Yildirim, Güliz Nigar Güncü, Dincer Göksülük, Melek Didem Tözüm, Mehmet Colak, Tolga Fikret Tözüm
OBJECTIVES: The purpose of this study was to evaluate the prevalence of sinus mucosal thickening (MT) and mucosal appearance (MA) in a patient population as detected with cone beam computed tomography (CBCT) and to determine the effects of various disease and demographic factors on MT and MA. STUDY DESIGN: The retrospective study consisted of CBCT images of 1000 maxillary arches in 500 patients. The arches were divided into 3 groups (atrophic, partially atrophic, and nonatrophic) according to the type of the maxillary dental crest...
September 8, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/29029457/prognostic-relevance-of-protein-expression-clinical-factors-and-myd88-mutation-in-primary-bone-lymphoma
#4
Yong Xu, Jian Li, Jian Ouyang, Juan Li, Jingyan Xu, Qiguo Zhang, Yonggong Yang, Min Zhou, Jing Wang, Cuiling Zhang, Yueyi Xu, Ping Li, Rongfu Zhou, Bing Chen
Primary bone lymphomas (PBLs) are composed of malignant lymphoid cells presenting in osseous sites, without supra-regional lymph node or extranodal involvement. We systematically characterized the immunophenotype and the myeloid differentiation factor 88 (MYD88)-L265P gene mutation status in PBL. Clinical data from 19 patients with PBL treated at Nanjing Drum Tower Hospital between 2009 and 2015 were analyzed retrospectively. Protein expression patterns were identified immunohistochemically, and MYD88 mutation was assessed using polymerase chain reaction and direct DNA sequencing...
September 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/29019447/survival-of-patients-with-cd20-negative-variants-of-large-b-cell-lymphoma-an-analysis-of-the-national-cancer-data-base
#5
Lindor Qunaj, Jorge J Castillo, Adam J Olszewski
Using records from the National Cancer Data Base, we studied overall survival of CD20-negative variants of diffuse large B-cell lymphoma (DLBCL): primary effusion (PEL, N = 228), plasmablastic (PBL, N = 481), ALK-positive large B-cell (ALK + LBLC, N = 15), and human herpesvirus-8-positive DLBCL (HHV8 + DLBCL, N = 77). Three-year survival was 27% for PEL, 40% for PBL, 34% for ALK + LBCL, and 63% for HHV8 + DLBCL. Compared with unspecified DLBCL, and adjusting for clinical characteristics (including the HIV status), survival was significantly worse for PEL (hazard ratio [HR], 1...
October 11, 2017: Leukemia & Lymphoma
https://www.readbyqxmd.com/read/28993364/durable-complete-remission-with-combination-chemotherapy-and-bortezomib-in-hiv-associated-plasmablastic-lymphoma
#6
Nivedita Arora, Arjun Gupta, Navid Sadeghi
Plasmablastic lymphoma (PBL) is an aggressive form of non-Hodgkin's lymphoma (NHL) classically seen in patients infected with the human immunodeficiency virus, but can also be seen in other immunocompromised states such as transplant recipients, autoimmune diseases and the elderly. PBL is generally associated with a poor prognosis despite chemotherapy. There is evidence supporting the use of bortezomib in combination with standard chemotherapy to achieve durable responses in patients with PBL. We describe a patient with acquired immunodeficiency syndrome who presented with rectal pain and bright red blood per rectum...
October 9, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28974125/prevalence-of-depressive-symptoms-among-medical-students-taught-using-problem-based-learning-versus-traditional-methods
#7
José Aderval Aragão, Marianna Ribeiro de Menezes Freire, Lucas Guimarães Nolasco Farias, Sarah Santana Diniz, Felipe Matheus Sant'anna Aragão, Iapunira Catarina Sant'anna Aragão, Tarcisio Brandão Lima, Francisco Prado Reis
OBJECTIVE: To compare depressive symptoms among medical students taught using problem-based learning (PBL) and the traditional method. MATERIAL AND METHODS: Beck's Depression Inventory was applied to 215 medical students. The prevalence of depression was calculated as the number of individuals with depression divided by the total number in the sample from each course, with 95% confidence intervals. The statistical significance level used was 5% (p ≤ .05). RESULTS: Among the 215 students, 52...
October 3, 2017: International Journal of Psychiatry in Clinical Practice
https://www.readbyqxmd.com/read/28970465/exploring-a-problem-based-learning-approach-in-pharmaceutics
#8
Barbara McKenzie, Alyson Brown
OBJECTIVE: The basis of this study was to explore the impact of the initiation of a Problem-Base Learning (PBL) approach within a second-year pharmaceutics degree on a Master of Pharmacy programme, introduced as a way of improving deep learning and to foster independent learning. DESIGN: A semi-structured interview was used to seek feedback from the students, and feedback from staff was secured though a focus group. A thematic approach was used for the analysis, once data saturation had been reached...
September 20, 2017: Pharmacy (Basel, Switzerland)
https://www.readbyqxmd.com/read/28963907/bortezomib-in-plasmablastic-lymphoma-a-glimpse-of-hope-for-a-hard-to-treat-disease
#9
REVIEW
Thomas A Guerrero-Garcia, Renzo J Mogollon, Jorge J Castillo
Plasmablastic lymphoma (PBL) is a rare and hard to treat disease. With current standard chemotherapeutic regimens, PBL is associated with a median overall survival of 12-15 months. We performed a systematic review of the literature through March 31, 2017 looking for patients with a diagnosis of PBL who were treated with bortezomib, alone or in combination. We identified 21 patients, of which 11 received bortezomib in the frontline setting and 10 received bortezomib in the relapsed setting. Eleven patients were HIV-positive and 10 were HIV-negative...
September 27, 2017: Leukemia Research
https://www.readbyqxmd.com/read/28932135/effectiveness-of-two-interactive-educational-methods-to-teach-tobacco-cessation-counseling-for-senior-dental-students
#10
Mina Ahmadian, Mohammad Reza Khami, Arezoo Ebn Ahamdi, Samaneh Razeghi, Reza Yazdani
OBJECTIVE: Nowadays, one of the major health problems in many countries is tobacco use. Dental professionals are in a unique position to promote smoking cessation since they have the opportunity for regular interaction with their patients. The purpose of the present study was to compare the effectiveness of two educational methods to teach tobacco cessation counseling (TCC) in dental practice for senior dental students. MATERIALS AND METHODS: In this interventional study, 93 eligible senior dental students from two dental schools in Tehran, Iran were randomly divided into two groups...
July 2017: European Journal of Dentistry
https://www.readbyqxmd.com/read/28929004/intraocular-plasmablastic-lymphoma-in-a-hiv-patient
#11
Carolline Fontes Alves Mariano, Glauce Lunardelli Trevisan, Antonio Augusto Velasco E Cruz, Fernando Chahud
Plasmablastic lymphoma (PBL) is a rare B-cell lymphoma occurring mainly in HIV patients. The tumor frequently involves extranodal sites such as the oral cavity, nasal cavity, gastrointestinal tract, skin, and lungs. The neoplastic cells are characterized by a plasmablastic appearance and typical immunophenotype that indicates plasma cell differentiation. Herein, we report a case of intraocular involvement by plasmablastic lymphoma in a HIV patient with a long history of cytomegalovirus retinitis and loss of vision...
2017: Case Reports in Pathology
https://www.readbyqxmd.com/read/28923370/nursing-students-perceptions-of-preparation-to-engage-in-patient-education
#12
Elizabeth Richard, Teresa Evans, Bev Williams
Patient teaching is a key component of graduate nursing practice. Nurses sometimes believe that their undergraduate teaching does not prepare them to engage in effective patient teaching. In addition, nursing students often do not use teaching resources when engaging in patient teaching. The aim of this focused ethnographic study was to determine if students in a CBL/PBL based learning undergraduate nursing program engage in patient teaching when they are in the clinical area. Focus groups and shorter individual interviews were used to ensure in-depth data collection...
September 9, 2017: Nurse Education in Practice
https://www.readbyqxmd.com/read/28915427/breast-lymphoma-in-a-patient-with-b-cell-non-hodgkin-lymphoma-a-case-report-study
#13
Spyridon Marinopoulos, Panagiotis Safioleas, Lamprini Skorda, Eleni Vassilopoulou, Flora Zagouri, Maria Sotiropoulou, Peter Drakakis, Constantine Dimitrakakis
INTRODUCTION: Breast involvement in Non Hodgkin Lymphoma is a rare entity as it accounts for 2.2% of all extranodal lymphomas. PRESENTATION OF CASE: A 59-year-old woman was referred to our Breast Unit because of two nodules of the right breast newly discovered during her annual mammography. Moreover, during the physical examination, a red-brown itchy lump of the scalp was discovered. The punch biopsies of the scalp lesion and ultrasound-guided core biopsies of both nodules of the right breast, revealed the presence of diffuse large B-cell Non Hodgkin Lymphoma in all tissue specimen sites...
September 7, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28894005/varicose-and-cheerio-collaborate-with-pebble-to-mediate-semaphorin-1a-reverse-signaling-in-drosophila
#14
Sangyun Jeong, Da-Som Yang, Young Gi Hong, Sarah P Mitchell, Matthew P Brown, Alex L Kolodkin
The transmembrane semaphorin Sema-1a acts as both a ligand and a receptor to regulate axon-axon repulsion during neural development. Pebble (Pbl), a Rho guanine nucleotide exchange factor, mediates Sema-1a reverse signaling through association with the N-terminal region of the Sema-1a intracellular domain (ICD), resulting in cytoskeletal reorganization. Here, we uncover two additional Sema-1a interacting proteins, varicose (Vari) and cheerio (Cher), each with neuronal functions required for motor axon pathfinding...
September 26, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28893071/a-model-of-collaboration-for-the-implementation-of-problem-based-learning-in-nursing-education-in-south-africa
#15
Mahlasela A Rakhudu, Mashudu Davhana-Maselesele, Ushonatefe Useh
BACKGROUND: The idea of collaboration between key stakeholders in nursing education for the implementation of problem-based learning (PBL) may have far-reaching implications for the institutions and students. MAIN OBJECTIVE: To develop a model of collaboration to facilitate the implementation of PBL in nursing education. METHODOLOGY: An exploratory sequential design was used. Qualitative data were collected from purposively recruited nurse educators from three universities in South Africa offering PBL and nurse managers from all the three hospitals in North West Province where PBL students are placed for clinical learning...
August 28, 2017: Curationis
https://www.readbyqxmd.com/read/28891721/the-regions-on-the-light-chain-of-botulinum-neurotoxin-type-a-recognized-by-t-cells-from-toxin-treated-cervical-dystonia-patients-the-complete-human-t-cell-recognition-map-of-the-toxin-molecule
#16
Minako Oshima, Philip Deitiker, Joseph Jankovic, M Zouhair Atassi
We have recently mapped the in vitro proliferative responses of T cells from botulinum neurotoxin type A (BoNT/A)-treated cervical dystonia (CD) patients with overlapping peptides encompassing BoNT/A heavy chain (residues 449-1296). In the present study, we determined the recognition profiles, by peripheral blood lymphocytes (PBL) from the same set of patients, of BoNT/A light (L) chain (residues 1-453) by using 32 synthetic overlapping peptides that encompassed the entire L chain. Profiles of the T-cell responses (expressed in stimulation index, SI; Z score based on transformed SI) to the peptides varied among the patients...
September 11, 2017: Immunological Investigations
https://www.readbyqxmd.com/read/28883212/verification-of-learning-effects-by-team-based-learning
#17
Shin-Ichi Ono, Yoshihisa Ito, Kumiko Ishige, Norio Inokuchi, Yasuhiro Kosuge, Satoru Asami, Megumi Izumisawa, Hiroko Kobayashi, Hiroyuki Hayashi, Takashi Suzuki, Yukinaga Kishikawa, Harumi Hata, Eiji Kose, Kei-Ichi Tabata
It has been recommended that active learning methods, such as team-based learning (TBL) and problem-based learning (PBL), be introduced into university classes by the Central Council for Education. As such, for the past 3 years, we have implemented TBL in a medical therapeutics course for 4-year students. Based upon our experience, TBL is characterized as follows: TBL needs fewer teachers than PBL to conduct a TBL module. TBL enables both students and teachers to recognize and confirm the learning results from preparation and reviewing...
September 5, 2017: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/28878909/a-rare-case-of-epstein-barr-virus-related-plasmacytoma-involving-maxillary-sinus-mucosa
#18
Julie D Gibbs, Marino E Leon, Kenia Liu, Johnny Nguyen, Ling Zhang
Extramedullary plasmacytomas, Epstein-Bar virus (EBV) associated, are rarely encountered and usually have a fairly good clinical outcome. EBV+ plasmacytoma may cause a diagnostic dilemma as it phenotypically resembles an aggressive plasmablastic lymphoma (PBL). Herein, we report a unique case with maxillary EBV+ plasmacytoma from a 76-year-old immunocompetent individual.
September 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28862126/diffuse-large-b-cell-lymphoma-in-a-male-breast-a-rare-case-report
#19
Adelina Birceanu Corobea, Adrian Dumitru, Maria Sajin, Radu Poenaru, Ana Puşcaşu, Dragoş Chirita, Anca Evsei
Primary breast diffuse large B cell lymphoma (PBL) in male patients represents a rare clinical phenomenon and can imitate a breast carcinoma in its clinical presentation, so, therefore, the initial treatment for most patients remains surgery. Prompt diagnosis associating subsequent treatment combining chemotherapy and radiotherapy are of the utmost importance. We herein report a 56 years old male patient diagnosed with diffuse large B cell lymphoma, after clinically presenting with a visible tumor in the left breast and showing no axillary lymphadenopathy...
July 2017: Chirurgia
https://www.readbyqxmd.com/read/28860565/interleukin-6-dependent-growth-in-a-newly-established-plasmablastic-lymphoma-cell-line-and-its-therapeutic-targets
#20
Sohtaro Mine, Tsunekazu Hishima, Akihiko Suganuma, Hitomi Fukumoto, Yuko Sato, Michiyo Kataoka, Tsuyoshi Sekizuka, Makoto Kuroda, Tadaki Suzuki, Hideki Hasegawa, Masashi Fukayama, Harutaka Katano
Plasmablastic lymphoma (PBL) is a rare, highly aggressive subtype of non-Hodgkin lymphoma with plasma-cell differentiation occurring typically in immune-suppressed patients such as those with AIDS. This study reports the establishment and characterization of a new cell line, PBL-1, derived from a patient with AIDS-associated PBL. Morphological assessment of PBL-1 indicated plasma-cell differentiation with a CD20(-) CD38(+) CD138(+) immunophenotype and IgH/c-myc translocation. The cell line harbours Epstein-Barr virus, but a 52...
August 31, 2017: Scientific Reports
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