keyword
https://read.qxmd.com/read/38545989/-development-and-exploration-of-the-national-first-class-undergraduate-course-in-enzyme-engineering
#1
JOURNAL ARTICLE
Hualei Wang, Weijie Gao, Meng Xu, Jinping Lin, Xuedong Wang, Dongzhi Wei
The biotechnology industry is a strategic emerging industry in our country, holding a crucial position in the national economy. The training of innovative high-quality professionals carries immense significance. As the cornerstone course in biotechnology, "Enzyme Engineering" directly impacts the students' caliber and industry development. This course aims to address pertinent issues present in the current curriculum delivery, such as inadequately optimized content, excessive dependency on textbooks, and reliance on monotonous teaching methods...
March 25, 2024: Sheng Wu Gong Cheng Xue Bao, Chinese Journal of Biotechnology
https://read.qxmd.com/read/38537834/influence-of-boundary-layer-jets-on-the-vertical-distribution-of-ozone-in-guangdong-china
#2
JOURNAL ARTICLE
Yuanping He, Shaojia Fan, Yiming Wang, Yiming Liu, Xiao Lu, Haolin Wang, Cheng He, Chuying Mai, Yu Du
The planetary boundary layer (PBL) characteristics during ozone (O3 ) episodes in China have been extensively studied; however, knowledge of the impact of boundary layer jets (BLJs) on O3 vertical distribution is limited. This study conducted a field campaign from 1 to 8 December 2020 to examine the vertical structure of the O3 concentration and wind velocity within the boundary layer at two sites (Foshan: FS, Maoming: MM) in Guangdong. Utilising lidar observations and the Weather Research and Forecasting model coupled with Chemistry (WRF-Chem), distinct spatial distribution patterns of O3 over FS and MM influenced by BLJs were identified...
March 25, 2024: Science of the Total Environment
https://read.qxmd.com/read/38535837/exploring-the-effectiveness-of-problem-based-learning-in-an-international-undergraduate-program-in-veterinary-sciences-students-satisfaction-experience-and-learning
#3
JOURNAL ARTICLE
Anna Broseghini, Miina Lõoke, Marta Brscic, Juliana Raffaghelli, Barbara Cardazzo, Antonella Lotti, Laura Cavicchioli, Lieta Marinelli
The systematic evaluation of the integration of problem-based learning (PBL) into educational programs in Italy is scarce and there are no published reports of its use in an Italian Bachelor of Veterinary Science degree program. This paper aims to assess the satisfaction of second-year students on an international Bachelor of Veterinary Science degree program after implementing two weeks of PBL with a multidisciplinary approach. Moreover, the impact of this methodological approach on the students' performance and their perceptions concerning their learning experience was investigated...
February 27, 2024: Veterinary Sciences
https://read.qxmd.com/read/38534298/multilevel-modeling-analysis-of-odontogenic-risk-factors-and-nasal-septum-deviation-associated-with-maxillary-sinus-mucosal-thickening-a-cone-beam-computed-tomography-study
#4
JOURNAL ARTICLE
Marwa Madi, Sara S Alsaad, Nada AlAssiry, Dina Attia, Mansour AlAssiry, Osama Zakaria
(1) Background: In this study, the impact of odontogenic risk factors with nasal septum deviation on maxillary sinus mucosal thickening was assessed using Cone-beam computed tomography CBCT. (2) Methods: A total of 328 maxillary sinus regions from 164 patients (85 males and 79 females) were examined. Images were interpreted by dental specialists and Otolaryngologists. Coronal and sagittal sections were examined to assess the proximity of the root tips of posterior maxillary teeth (RPMT) to the maxillary sinus...
March 13, 2024: Dentistry Journal
https://read.qxmd.com/read/38533042/enhancing-creative-cognition-through-project-based-learning-an-in-depth-scholarly-exploration
#5
REVIEW
Hao Yu
This study rigorously examines Project-Based Learning's (PBL) efficacy in augmenting creative thinking within educational frameworks. It investigates PBL's alignment with psychological tenets and cognitive processes to bolster creative capacities. Employing an extensive literature review, the research scrutinizes PBL's psychological and educational merits, project design, student engagement, cognitive growth, and the amalgamation of intellectual and affective elements. Findings reveal PBL's adaptability to cognitive rhythms, its role in amplifying information intake and motivation, and its enhancement of cognitive engagement and dynamic thought application...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38515169/factors-affecting-pharmacology-learning-in-integrated-pbl-in-diverse-medical-students-a-mixed-methods-study
#6
JOURNAL ARTICLE
S A Nicolaou, I Televantou, A Papageorgiou, A P Albert, A W Hitchings, P McCrorie, Persoulla Nicolaou
INTRODUCTION: Problem-based learning (PBL) was introduced to address passive teaching limitations. However, it is not fully characterised as a teaching modality in pharmacology. The present study investigated the factors affecting pharmacology learning in an integrated PBL-based curriculum in diverse learners. METHODS: Year 1 undergraduate medical students from two cohorts at St. George's University of London and University of Nicosia, participated. Statistical analysis of pharmacology knowledge scores, at the beginning (pre-test) and end of the academic year (post-test), investigated readiness to benefit from PBL based on diverse student characteristics (educational background, age, gender, country of origin, ethnicity, native language, PBL experience)...
March 21, 2024: BMC Medical Education
https://read.qxmd.com/read/38510403/chatgpt-based-learning-generative-artificial-intelligence-in-medical-education
#7
EDITORIAL
Brandon Stretton, Joshua Kovoor, Matthew Arnold, Stephen Bacchi
UNLABELLED: Large language models like ChatGPT are a type of machine learning model that can offer a positive paradigm shift in case-based/problem-based learning (CBL/PBL). ChatGPT may be able to augment the existing paradigm to work in conjunction with the clinical-teacher in PBL/CBL case generation. It can develop realistic patient cases that could be revised by clinical teachers to ensure accuracy and relevance. Further, it can be directed to include specific case content in order to facilitate the constructive alignment of the case with the broader learning objectives of the curriculum...
February 2024: Medical Science Educator
https://read.qxmd.com/read/38510257/type-i-and-ii-interferons-transcription-factors-and-major-histocompatibility-complexes-were-enhanced-by-knocking-down-the-prrsv-induced-transforming-growth-factor-beta-in-monocytes-co-cultured-with-peripheral-blood-lymphocytes
#8
JOURNAL ARTICLE
Dante Fabros, Wasin Charerntantanakul
The innate and adaptive immune responses elicited by porcine reproductive and respiratory syndrome virus (PRRSV) infection are known to be poor. This study investigates the impact of PRRSV-induced transforming growth factor beta 1 (TGFβ1) on the expressions of type I and II interferons (IFNs), transcription factors, major histocompatibility complexes (MHC), anti-inflammatory and pro-inflammatory cytokines in PRRSV-infected co-cultures of monocytes and peripheral blood lymphocytes (PBL). Phosphorothioate-modified antisense oligodeoxynucleotide (AS ODN) specific to the AUG region of porcine TGFβ1 mRNA was synthesized and successfully knocked down TGFβ1 mRNA expression and protein translation...
2024: Frontiers in Immunology
https://read.qxmd.com/read/38500040/comprehensive-genomic-analysis-of-bacillus-subtilis-and-bacillus-paralicheniformis-associated-with-the-pearl-millet-panicle-reveals-their-antimicrobial-potential-against-important-plant-pathogens
#9
JOURNAL ARTICLE
Mushineni Ashajyothi, Shivannegowda Mahadevakumar, Y N Venkatesh, Pullabhotla V S R N Sarma, Chalasani Danteswari, Alexander Balamurugan, Ganesan Prakash, Vikas Khandelwal, C Tarasatyavathi, Appa Rao Podile, Mysore S Kirankumar, Siddaiah Chandranayaka
BACKGROUND: Plant microbiome confers versatile functional roles to enhance survival fitness as well as productivity. In the present study two pearl millet panicle microbiome member species Bacillus subtilis PBs 12 and Bacillus paralicheniformis PBl 36 found to have beneficial traits including plant growth promotion and broad-spectrum antifungal activity towards taxonomically diverse plant pathogens. Understanding the genomes will assist in devising a bioformulation for crop protection while exploiting their beneficial functional roles...
March 18, 2024: BMC Plant Biology
https://read.qxmd.com/read/38481223/sociocultural-factors-affecting-first-year-medical-students-adjustment-to-a-pbl-program-at-an-african-medical-school
#10
JOURNAL ARTICLE
Masego B Kebaetse, Dominic Griffiths, Gaonyadiwe G Mokone, Mpho S Mogodi, Brigid G Conteh, Oathokwa Nkomazana, John Wright, Rosemary Falama, Maikutlo Kebaetse
BACKGROUND: Besides regulatory learning skills, learning also requires students to relate to their social context and negotiate it as they transition and adjust to medical training. As such, there is a need to consider and explore the role of social and cultural aspects in student learning, particularly in problem-based learning, where the learning paradigm differs from what most students have previously experienced. In this article, we report on the findings of a study exploring first-year medical students' experiences during the first semester of an undergraduate problem-based learning medical program at an African medical school...
March 13, 2024: BMC Medical Education
https://read.qxmd.com/read/38477502/high-burden-of-clonal-mast-cell-disorders-and-hereditary-%C3%AE-tryptasemia-in-patients-who-need-hymenoptera-venom-immunotherapy
#11
JOURNAL ARTICLE
Peter Korošec, Gunter J Sturm, Jonathan J Lyons, Tinkara Pirc Marolt, Manca Svetina, Mitja Košnik, Mihaela Zidarn, Mark Kačar, Nina Frelih, Nika Lalek, Ajda Demšar Luzar, Samo Zver, Matevž Škerget, Ewa Czarnobilska, Wojciech Dyga, Sanja Popović Grle, Miroslav Samarzija, Lisa Arzt-Gradwohl, Urban Čerpes, Grzegorz Porebski, Branko Pevec, Eva Schadelbauer, Peter Kopač, Julij Šelb, Matija Rijavec
BACKGROUND: In patients who require venom immunotherapy (VIT), there is a need to identify underlying mast cell (MC) disorders since these may affect the risk and severity of future sting reactions and the long-term effectiveness of VIT. METHODS: 1319 individuals with Hymenoptera venom allergy (HVA) who needed VIT from referral centers in Slovenia, Austria, Croatia, and Poland underwent examination for KIT p.D816V in peripheral blood leukocytes (PBL) using a highly sensitive PCR test and tryptase genotyping by digital droplet PCR...
March 13, 2024: Allergy
https://read.qxmd.com/read/38477492/clinical-value-of-endoscopic-ultrasound-sound-speed-in-differential-diagnosis-of-pancreatic-solid-lesion-and-prognosis-of-pancreatic-cancer
#12
JOURNAL ARTICLE
Jianing Qiu, Kangrong Li, Xiuyan Long, Xiaoyu Yu, Pan Gong, Yu Long, Xiaoyan Wang, Li Tian
BACKGROUND: Differential diagnosis of pancreatic solid lesion (PSL) and prognosis of pancreatic cancer (PC) is a clinical challenge. We aimed to explore the differential diagnostic value of sound speed (SS) obtained from endoscopic ultrasonography (EUS) in PSL and the prognostic value of SS in PC. METHODS: Patients with PSL in The Third Xiangya Hospital of Central South University from March 2019 to October 2019 were prospectively enrolled, who obtained SS from PSL...
March 2024: Cancer Medicine
https://read.qxmd.com/read/38476255/enhancing-surgical-nursing-student-performance-comparative-study-of-simulation-based-learning-and-problem-based-learning
#13
JOURNAL ARTICLE
Lihe Ma, Rui Yan, Xiang Wang, Xiaohong Gao, Na Fan, Linmei Liu, Haifen Kang
BACKGROUND: Surgical nursing is a high-risk, high-pressure, and complex field. Nurses need extensive knowledge, skills, and abilities. Problem-Based Learning (PBL) and Simulation-Based Learning (SBL) are effective student-centered methods. Which method is better for surgical nurse training? More research is needed to determine the best approach for undergraduate surgical nurse education. PURPOSE: To compare the impact of PBL and SBL on undergraduate nursing students' performance and improve learning outcomes in surgical nursing education...
2024: Journal of Multidisciplinary Healthcare
https://read.qxmd.com/read/38463801/unveiling-the-dynamics-of-self-regulated-learning-in-project-based-learning-environments
#14
JOURNAL ARTICLE
Xiu-Yi Wu
Project-based learning (PBL) has been found to exert a positive influence on learners' academic achievements, while also fostering their intrinsic motivation and playing a crucial role in nurturing sustainable learning capacities. Understanding individual differences in self-regulated learning (SRL) within project-based foreign language learning can guide language teachers in delivering personalized instruction. This study utilized a blended learning management system to collect and analyze data on SRL from 95 learners enrolled in a project-based College English course...
March 15, 2024: Heliyon
https://read.qxmd.com/read/38459551/use-of-problem-based-learning-in-orthopaedics-education-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#15
JOURNAL ARTICLE
Ting Li, Ruohong Song, Wenjie Zhong, Wenao Liao, Jiang Hu, Xilin Liu, Fei Wang
BACKGROUND: Currently, problem-based learning (PBL) has been widely used in many disciplines, but no systematic review has explored the advantages and disadvantages of PBL in orthopaedics education. METHODS: We searched the PubMed, Cochrane Library, Embase, Web of Science, Scopus, Chongqing VIP Database (VIP), Chinese National Knowledge Infrastructure (CNKI), and Wanfang databases up to April 2023 to identify for relevant studies. Relevant studies were identified by using specific eligibility criteria, and data were extracted...
March 8, 2024: BMC Medical Education
https://read.qxmd.com/read/38437978/determination-of-whole-blood-loss-from-minimally-invasive-myomectomy-using-a-standardized-formula-a-pilot-study
#16
JOURNAL ARTICLE
Marisa Gigg, Kathryn Goldrath, Alexandra Havard, Anissa V Nguyen, Lorna Kwan, Ram Parvataneni, Sukrant Mehta, Alexander Chiang, Valentina Rodriguez, Jacqueline Fahey
STUDY OBJECTIVE: To determine the median perioperative blood loss (PBL) during minimally invasive surgical (MIS) myomectomy. DESIGN: Prospective pilot study. SETTING: Large academic teaching hospital. PATIENTS: 31 patients underwent laparoscopic or robotic myomectomy and completed a postoperative complete blood count (CBC) from November 2020 to August 2022. Patients had to have at least one fibroid greater than or equal to 3 cm on preoperative imaging...
March 2, 2024: Journal of Minimally Invasive Gynecology
https://read.qxmd.com/read/38415257/plasmablastic-lymphoma-current-knowledge-and-future-directions
#17
REVIEW
Ji-Wei Li, Hong-Ling Peng, Xiao-Yan Zhou, Jing-Jing Wang
Plasmablastic lymphoma (PBL) is an aggressive non-Hodgkin lymphoma associated with HIV infection and immunodeficiency. However, PBL can also be seen immunocompetent individuals in recent studies. PBL was characterized by distinct clinical and pathological features, such as plasmablastic morphology and universal expression of plasma cell markers. The clinicopathologic features were different between HIV-negative and HIV-positive patients. Gene expression analysis identified the unique molecular feature in PBL, including frequent c- MYC rearrangement and downregulation of BCR signaling pathway...
2024: Frontiers in Immunology
https://read.qxmd.com/read/38406544/b-cell-maturation-antigen-expression-and-clinical-features-of-plasmablastic-lymphoma
#18
JOURNAL ARTICLE
Ning Dong, Hailing Zhang, Jinming Song, Jamila Mammadova, Bijal Shah, Hayder Saeed, Sameh Gaballa, Ariel Grajales-Cruz, Leidy Isenalumhe, Celeste Bello, Lubomir Sokol, Javier Pinilla, Julio Chavez
No abstract text is available yet for this article.
February 2024: EJHaem
https://read.qxmd.com/read/38397734/mulberry-leaf-polysaccharides-attenuate-oxidative-stress-injury-in-peripheral-blood-leukocytes-by-regulating-endoplasmic-reticulum-stress
#19
JOURNAL ARTICLE
Wenqiang Jiang, Yan Lin, Linjie Qian, Siyue Lu, Huaishun Shen, Xianping Ge, Linghong Miao
The present study assessed the protective effects and underlying mechanisms of mulberry leaf polysaccharides (MLPs) against hydrogen peroxide (H2 O2 )-induced oxidative stress injury in the peripheral blood leukocytes (PBLs) of Megalobrama amblycephala . Five treatment groups were established in vitro: the NC group (PBLs incubated in an RPMI-1640 complete medium for 4 h), the HP group (PBLs incubated in an RPMI-1640 complete medium for 3 h, and then stimulated with 100 μM of H2 O2 for 1 h), and the 50/100/200-MLP pre-treatment groups (PBLs were pre-treated with MLPs (50, 100, and 200 μg/mL) for 3 h, and then stimulated with 100 μM of H2 O2 for 1 h)...
January 23, 2024: Antioxidants (Basel, Switzerland)
https://read.qxmd.com/read/38395850/improving-undergraduate-education-of-occupational-health-and-occupational-medicine-appling-massive-open-online-courses-problem-based-learning
#20
JOURNAL ARTICLE
Rui Ding, Han Cheng
BACKGROUND: The learning of Occupational Health and Occupational Medicine in undergraduate college students in China has been hindered by various factors. This study aimed to explore the effects of the application of Massive Open Online Courses (MOOC) & Problem-based learning (PBL) in the learning of Occupational Health and Occupational Medicine in undergraduate college students in China. METHODS: Students enrolled in 2017 and 2018 were categorized in the control group and study group, and received PBL learning and MOOC + PBL learning, respectively...
February 23, 2024: BMC Medical Education
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